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baradaran-jafari--navid
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Mitigating DDoS Using BOTNET Analysis with Flow Anomaly Detection
, M.Sc. Thesis Sharif University of Technology ; Jafari, Mahdi (Supervisor) ; Endicott-Popovsky, Barbara (Co-Advisor)
Abstract
Internet is the largest multi-purpose, self-reliant, complex and distributed computer network across the globe. The nodes of this network are placed in every place like homes, offices, military camps, schools and all other locations by utilizing many different communication protocols, media and capacities. Furthermore, by rapid technology development, there are many newly born applications utilizing internet in new ways such as Internet of Things systems. The explosive growth of technology causing accelerated addition of new nodes to the internet, and any new single node may have several new unpatched vulnerabilities. This is a serious issue for managing this vast chaotic configuration and...
Recent clinical findings on the role of kinase inhibitors in COVID-19 management
, Article Life Sciences ; Volume 306 , 2022 ; 00243205 (ISSN) ; Baghbanzadeh, A ; Nakhlband, A ; Baradaran, B ; Jafari, S ; Bagheri, Y ; Raei, F ; Montazersaheb, S ; Farahzadi, R ; Sharif University of Technology
Elsevier Inc
2022
Abstract
The highly pathogenic, novel coronavirus disease (COVID-19) outbreak has emerged as a once-in-a-century pandemic with poor consequences, urgently calling for new therapeutics, cures, and supportive interventions. It has already affected over 250 million people worldwide; thereby, there is a need for novel therapies to alleviate the related complications. There is a paradigm shift in developing drugs and clinical practices to combat COVID-19. Several clinical trials have been performed or are testing diverse pharmacological interventions to alleviate viral load and complications such as cytokine release storm (CRS). Kinase-inhibitors have appeared as potential antiviral agents for COVID-19...
Utilizing Gaussian Processes to Learn Dynamics of Unknown Torques Acting on a Spacecraft
, M.Sc. Thesis Sharif University of Technology ; Kiani, Maryam (Supervisor)
Abstract
Accurate and fast attitude estimation of a rigid body plays an essential role in the performance of a vehicle’s control system, especially aerospace vehicles. Ample works have been done to increase the accuracy and speed of the attitude estimation process, but all have been developed according to a model-based approach. This approach assumes that the torques acting on the body have a known dynamical model that is used for the attitude estimation. The purpose of the present research is to estimate the attitude via a model-free approach, i. e. dynamics of the torques acting on the body are no longer assumed to be known, and its learning is the next step. Thus, the problem formulation of this...
Fuzzy system design for automatic irrigation of agricultural fields
, Article Expert Systems with Applications ; Volume 210 , 2022 ; 09574174 (ISSN) ; Tavazoei, M. S ; Sharif University of Technology
Elsevier Ltd
2022
Abstract
One of the main challenges in arid and semi-arid regions is the lack of water for various purposes such as industrial and agricultural applications. The problem is even more significant in traditional agriculture. The geographical location, climatic conditions, average annual rainfall, vegetation, air pollution and turbidity, and canopy of plants are important and lead to different water consumption in plants. Therefore, proper water consumption in agriculture in most countries leads to food security and a better supply of crops. In this research, we propose a fuzzy system that has eight inputs and seven outputs. Inputs include soil moisture, relative humidity, air temperature, wind speed,...
Proposing a Combined BTB and Data Cache Architecture for Modern Processors
, M.Sc. Thesis Sharif University of Technology ; Sarbazi Azad, Hamid (Supervisor)
Abstract
Modern pipelined processors use a memory array named Branch Target Buffer (BTB) to reduce the performance penalty due to conditional braches by predicting path of the branch and keeping useful history-based information for future accesses. Today BTB is a fixed size and small memory array located near the processor. By the way, BTB, in the best case, should be large enough to accommodate all conditional branches throughout the running program. Moreover, small size BTB presents much fast access and is practical on-chip storage for a system with limited power budget.
Considering role in the memory hierarchy, on the other hand, the system performance is highly correlated to the L1 data cache...
Considering role in the memory hierarchy, on the other hand, the system performance is highly correlated to the L1 data cache...
, M.Sc. Thesis Sharif University of Technology ; Dolati, Abolghasem (Supervisor)
Abstract
Electrodeposition of composite coatings containing nano particles is very important because this technique is simple and economic. In this research, in order to produce a coating with high hardness and wear resistance, Ni-Co/WC nano composite was co-deposited. Watt’s based bath containing cobalt and tungsten carbide was used and parameters such as preparation of solution, concentration of ingredients and current density were controlled and adjusted. Surface morphology, microstructure and mechanical properties of coatings were studied by SEM and AFM microscopes. Mechanism of electrodeposition was investigated by cyclic voltametry, cronoamperometry and cronopotentiometry techniques and...
Lumbopelvic Rhythm during Forward and Backward Sagittal Trunk Rotations; in vivo Measurements Using Inertial Sensors
, M.Sc. Thesis Sharif University of Technology ; Arjmand, Navid (Supervisor)
Abstract
Direct in vivo measurements of spinal loads and muscle forces are invasive. Investigators have thus used musculoskeletal biomechanical models that require kinematic data including trunk and pelvis angular movements as their inputs. . Novel devices measure anglular movements using both inertial sensors (such as gyroscopes and accelerometers) and miniature magnetometers. Relative low cost, portability, and accuracy are among specific characteristics of inertial tracking devices. The main objective of the present study was set to measure spinal kinematics including the lumbopelvic rhythm as the ratio of total lumbar rotation over pelvic rotation during trunk sagittal movement which is essential...
Evaluation of 1991 NIOSH Lifting Equation in Controlling the Biomechanical Loads of the Human Spine
, M.Sc. Thesis Sharif University of Technology ; Arjmand, Navid (Supervisor)
Abstract
The 1991 NIOSH Lifting Equation (NLE) is widely used to assess risk of injury to the spine by providing estimates of the recommended weight limit (RWL) in hands. The present study uses two biomechanical models of the spine to verify whether the RWL generates L5-S1 loads within the limits (e.g., 3400 N for compression recommended by NIOSH and 1000 N for shear recommended in some studies).Severallifting activities are simulated here to evaluate the RWL by the NLE and the L5-S1 loads by the models. In lifting activities involving moderate to large forward trunk flexion, the estimated RWL generates L5-S1 spine loads exceeding the recommended limits. The NIOSH vertical multiplier is the likely...
Sagittal Range of Motion of the Thoracic Spine Using Inertial Tracking Device and Effect of Measurement Errors on Model Predictions
, M.Sc. Thesis Sharif University of Technology ; Arjmand, Navid (Supervisor)
Abstract
Range of motion (ROM) of the thoracic spine has implications in patient discrimination for diagnostic purposes and in biomechanical models for predictions of spinal loads. Few previous studies have reported quite different thoracic ROMs. Total (T1-T12), lower (T5-T12) and upper (T1-T5) thoracic, lumbar (T12-S1), pelvis, and entire trunk (T1) ROMs were measured using an inertial tracking device as asymptomatic subjects flexed forward from their neutral upright position to full forward flexion. Correlations between body height and the ROMs were conducted. Effect of measurement errors of the trunk flexion (T1) on the model-predicted spinal loads was investigated. Mean of peak voluntary total...
A Detailed Finite Element Model of the Lumbar Spine under Muscle Forces
, M.Sc. Thesis Sharif University of Technology ; Arjmand, Navid (Supervisor)
Abstract
Etiological studies proves the fact that Low Back Pain (LBP) is one of the most expensive and prevalent desease all over the world. This fact illustrates the reqiurment of the special effort in ordet to reducing the pain due to this problem. Finite element modeling of human spine is one the suitable methods to simulate the behavior of human spine in different loading conditions. These conditions could be different daily occupational tasks. There is two general viewpoint toward finite element modeling of human spine. The fisrt method focuses on the detailed geometry and mechanical properties of spine, while the other complexities such as detailed muscle forces are overlooked. The latter...
A Hyrid EMG-optimization Based Model of the Lumbar Spine to Estimate Muscle Forces in Different Tasks
, M.Sc. Thesis Sharif University of Technology ; Arjmand, Navid (Supervisor)
Abstract
Low back pains (LBP) are prevalent and costly. One of the important factors causing LBP is excessive axial compression and shear forces that are applied on the intervertebral discs during different activities. Due to lack of direct in vivo measurement methods for estimating these loads, musculoskeletal biomechanical models have been emerged as indispensable tools under various activities. Different biomechanical models have been suggested to estimate muscle forces and spinal loads base on optimization, EMG and hybrid (EMG assisted optimization, EMGAO) methods. Although there have been a number of studies on the differences between various optimization and EMG-based methods, there has been no...
Effect of Iatrogenic Muscle Injuries on Spine Biomechanics During Posterior Lumbar Surgeries Using a Biomechanical Model for Design of Rehabilitation Exercises
, M.Sc. Thesis Sharif University of Technology ; Arjmand, Navid (Supervisor)
Abstract
Posterior lumbar surgery is often associated with extensive injuries to back muscles. In this thesis, the effect of such iatrogenic injuries in some patients was examined. For this purpose, the CSA of back muscles in 6 patients were measured using MR scan. To examine any natural change in CSAs of healthy people or instrument errors, same measurement were carried out on 10 healthy volunteers. In addition, a detailed anatomical model of an intact human spine was developed. With the aim of experimental studies and intact model, the post-operative model of patients was also developed. These two models were used to quantizing the change in activity of back muscles during some symmetric, normal...
3D Measurements of the Thoracic and Lumbar Spine Range of Motions Using Inertial Sensors
, M.Sc. Thesis Sharif University of Technology ; Arjmand, Navid (Supervisor)
Abstract
Musculoskeletal abnormalities affect joints and change their range of motion (RoM). Correcting these abnormalities thoroughly depends on the information related to the normal spine movement. Therefore, spine motion analysis can be used as an important tool to distinguish between healthy and patient individuals as well as to determine the intensity of such diseases. Additionally, existing biomechanical models need kinematics data in order to analyze spinal forces. The present study hence aims to measure 3D range of motion of thoracic and lumbar spine using inertial sensors. Their small size, portability, low weight, and relatively low cost make inertial sensors as indispensable tools in...
A Novel Stability-based EMG-assisted Model of the Lumbar Spine to Estimate Trunk Muscle Forces and Spinal Loads in Various Static Activities
, M.Sc. Thesis Sharif University of Technology ; Arjmand, Navid (Supervisor)
Abstract
The spine like every other mechanical pillar, is exposed to buckling and loss of stability. While existing biomechanical models emphasize the pressure force on the disk as the main cause of injury, there is also a possibility of local buckling phenomenon in vertebral discs. Because of the prevalence and high cost of lower back pain, it is essential to evaluate the forces carried by disks and lumbar muscles during occupational activities more accurately. In this regard, hybrid EMG-assisted optimization (EMGAO) approaches are most common methods for estimation of spinal loads. These models, not only use EMG data to be physiologically creditable, but also satisfy equilibrium requirements at all...
Pull-out Strength Test Simulation and Stability Study of a Patient-Specific Drill Guide Template of Thoracic Pedicle Screw Placement for Patients with Spinal Deformity Using Finite Element Analysis
, M.Sc. Thesis Sharif University of Technology ; Arjmand, Navid (Supervisor)
Abstract
We have recently designed/fabricated novel bilateral vertebra- and patient-specific drill guides for pedicle screw (PS) placements and tested their accuracy for both nondeformed and deformed thoracic spines. PS placement deviations from their preplanned positions significantly reduced when guide template were used; the success rate improved from ~72% (freehand placements) to 94% (guided placements). In the present study, we aim to use finite element (FE) analyses to evaluate the pull-out strength of these PSs inserted via either the freehand technique or our drill-guide templates. Two 3D-printed T1-T12 thoracic models of a severe scoliosis patient with a 47° thoracic dextro-scoliotic curve...
Biomechanical Evaluation of the Niosh Equation in Stoop Versus Squat Load-Handling Activities Using a Full-Body Musculoskeletal Model
, M.Sc. Thesis Sharif University of Technology ; Arjmand, Navid (Supervisor)
Abstract
Objective: To assess adequacy of the National Institute for Occupational Safety and Health (NIOSH) Lifting Equation (NLE) in controlling lumbar spine loads below their recommended action limits during load-handling activities in the stoop and squat using a detailed musculoskeletal model,that is, the AnyBody Modeling System.Background: The NIOSH committee employed simplistic biomechanical models for the calculation of the spine compressive loads with no estimates of the shear loads. In addition, NLE does not include the posture of the knee during manual material handling. It is therefore unknown whether the NLE would adequately control lumbar compression and shear loads below their...
Human Whole-Body Static 3D Posture Prediction in One- and Two-Handed Lifting Tasks from Different Load Positions using Machine Learning
, M.Sc. Thesis Sharif University of Technology ; Arjmand, Navid (Supervisor)
Abstract
Biomechanical models require body posture to evaluate the risk of musculoskeletal injuries during daily/occupational activities like manual material handling (MMH). The procedure to measure body posture via motion-analysis techniques is complex, time-consuming, and limited to equipped laboratories. This study aims to develop an easy-to-use yet accurate model that predict human whole-body static posture (3D body coordinates and anatomical joint angles) during different MMH activities. Twenty healthy male right-handed individuals with body mass index between 18 and 26 performed 204 symmetric and asymmetric MMH activities. Each person reached (i.e., without any load in hands) the destinations...
Simulations of Dynamic Hand-Loading Activities by Using Musculoskeletal Modeling Based on Experimental Versus Full-Body Posture Prediction Neural Network Data
, M.Sc. Thesis Sharif University of Technology ; Arjmand, Navid (Supervisor)
Abstract
Body posture is an essential input of musculoskeletal models that evaluate spinal loads in occupational activities. Posture is either measured in vivo via video-camera motion capture systems or predicted via artificial neural networks (ANNs) [1]. As video-camera measurements are impractical for use in real workstations, we have recently developed an ANN that predicts full-body posture during one- and two-handed static load-handling activities. This ANN, trained based on the posture data of 20 subjects each performing 204 static load-handling activities, uses 3D coordinates of the hand-load, body weight, and body height of the worker to predict 3D coordinates of 41 full-body skin markers. The...
Effect of Lumbar Spine Lordosis on Intervertebral Joint Load Sharing Using Musculoskeletal and Finite Element Modeling
, M.Sc. Thesis Sharif University of Technology ; Arjmand, Navid (Supervisor)
Abstract
There is a large, at times contradictory body of investigations relating low back pain and spinal curvature in sagittal plane. The previous studies have not been subject-specified, and they have not considered the active tissues in the models. The mechanical load has a significant impact on the prevalence of low back pain and the geometry of lumbar spine in the sagittal plane is one of the most important characteristics in determining the load sharing of the spine. Thus, it is essential to know how the geometry load affects the load sharing of the lumbar spine. As a matter of fact, the purpose of this project is to know how the geometry of the lumbar spine affects the load sharing. Thus,...
Investigation and Management of the Risk of Musculoskeletal Injury in Workers of Irankhodro Assembly Line by Using Qualitative and Quantitative Tools in Occupational Biomechanics
, M.Sc. Thesis Sharif University of Technology ; Arjmand, Navid (Supervisor)
Abstract
According to epidemiological studies, low back pain is the most prevalent musculoskeletal disease thus indicating the important role of biomechanical engineers to manage risk of injury. Different quantitative (i.e., biomechanical models) and qualitative (empirical) assessment tools are used to evaluate risk of musculoskeletal injuries. The present study uses various quantitative and qualitative risk assessment tools to investigate the risk of injury among workers in Iran Khodro Automaker company (IKCO) assembly hall No. 3 (Pars Peugeot car assembly). Moreover, different engineering and administrative interventions are suggested to manage risk of musculoskeletal injuries when needed. The...