Sharif Digital Repository

In this study, aqueous two-phase systems (ATPS) containing Tween 20 as a biocompatible nonionic surfactant and three different salts (NH4HPO4, NH4CH3COO and Mg(CH3COO)2 ) were prepared and their extractive potential for Lysozyme enzyme was evaluated. These systems have surfactant-rich top phase and salt-rich bottom phase. Phase equilibrium diagrams at 23 ° C were obtained by using the cloud point method and the results were successfully fitted to the Merchuk correlation and their trends were correlated with the effective excluded volume (EEV) parameter. Afterward, the partitioning behavior of the lysozyme and its extraction efficiency in the systems of Tween 20/diammonium hydrogen phosphate,... 

Metal-organic frameworks (MOFs) are a new class of biocompatible nanomaterials with high specific surface area, which provide the possibility of loading various therapeutic agents. Considering the few studies on the use of MOFs in melanoma cancer treatment, the main goal of this research is to investigate the loading and controlling the release of dacarbazine (DTIC) and also the interaction of DTIC and MOF structure in aqueous environments. Based on this, this study was done in three main parts. In the first part, several types of well-known and often used structures in the drug delivery field, including ZIF-8 (based on zinc), MIL-101-NH2(Fe), and MIL-100(Fe) (both based on iron), were... 

Membrane bioreactors (MBRs) which are commonly understood as the combination of membrane filtration and biological treatment using activated sludge have several advantages, but membrane fouling reduces the membrane efficiency, permeability and lifetime. An alternative is replacing a moving bed biofilm reactor (MBBR) with the activated sludge system which may reduce the effect of membrane fouling. The sludge produced in MBBRs has poor settling characteristics, therefore, their efficiency is limited by the sedimentation tank performance and they require a larger settling surface. The combination of moving bed biofilm reactors and membrane bioreactors can compensate for the drawbacks of both of... 

Value at risk of an asset, is the asset’s expected maximum loss for a certain period of time and at a specified confidence level. Value-at-Risk can be calculated in the bank with its inter-nal method or standardized method. when a method have more violation number then bank need to keep more daily capital requirements. under the Basel 2 agreement if the violation of method more than 10 times in year, the Bank uses the standardized method.
There are trade off Between daily capital charge and violations. Therefore, existing methods for calculating the value at risk, usually lead to much daily capital charge or many violations. Studies show with combination of different methods to calculate... 

Journals and conferences in computer science are the major venue for publishing new achievement in the field. It is an expert opinion that a number of top conferences in computer science are even more important than journals. In this work we aim at studying this in terms of citation analysis. To this end, we took 100 top journals and 63 top conferences and extracted their citation graph through Scopus dataset. We then constructed the citation graph in which the nodes were the journals and conferences and the links corresponded to the citations of the papers. We used various measures to rank the nodes in the graph. The ranking methods included Prestige, PageRank, Eigenfactor, HITS and SALSA.... 

The long term evolution (LTE) standard is introduced and developed by the 3rd generation partnership project (3GPP) based on orthogonal frequency division multiplexing (OFDM). OFDM systems, in spite of having many advantages such high performance in bandwidth usage, are very sensitive to inter carrier interference (ICI) as a drawback. In order to prevent ICI, the frequency offset, mainly caused by the miss-match between oscillators' frequency and also between the sampling frequency of the transmitter and the receiver, should be estimated and compensated. Frequency synchronization is a part of the tasks of a synchronizer. In this thesis, main tasks of a synchronizer are illustrated and... 

Value-at-Risk (VaR) is the most commontool for risk management. This tool is used to measure market risk and also used as a basis in determining financial standards for international financial institutions. VaR is the maximum loss of the asset portfolio at the specified confidence level and certain time horizon. Many parametric, nonparametric and semi parametric methods have been invented for VaR estimation. Each one of these methods has its advantages and disadvantages and different methods may perform better in differnet situations.When estimating VaR, we can choose one of these methods or we can combine the VaRs estimated by different methods. There are few researches conducted on VaR... 

Complex networks science have received tremendous attention in recent years and the brain is one of the systems to which graph theoretical tools have been applied. Alzheimer’s disease (AD) is a neurodegenerative disease affecting many of elderly population. AD changes the anatomy of the brain, which subsequently results in changes in its functions. These changes have been frequently reported in signals recorded from the brain (such as MEG, fMRI and EEG). Among these neuroimaging techniques EEG is one of the most aproprate methods for extracting functional connectivites according to high temporal resolution. In this thesis, we aimed at analyzing the properties of EEG-based functional networks... 

In the recent years, the problem of modeling a cognitive task using phase oscillators has been receiving a significant attention. In this view, single neurons are no longer elementary computational units. Rather, coherent oscillating groups of neurons are seen as nodes of networks performing cognitive tasks. From this assumption, we develop a model of stimulus-response learning and recognition. The most significant part of our work is defining learning methods for natural frequencies and coupling weights in a coupled phase oscillator network under Kuramoto conditions. In this thesis, we improved the previous models by not only emphasizing on the frequency of the oscillators but also taking... 

Value at risk (VaR) is the maximum loss of the asset portfolio at the specified confidence level and certain time horizon. This tool is used to measure market risk and also used as a basis in determining financial standards for international financial instituation. Conditional Autoregressive Value at Risk models or CAViaR models introduced by Engle and Manganelli (2004). This models calculate VaR base on quantile regession approach and show some promising performance properties.
In order to propose a more accurate model for calcutating VaR , we develop CAViaR models by incorporating them with intraday information then we calculate VaR with this kind of models and CAViaR... 

Frequency scarcity has emerged the necessity of opportunistic utilization of frequency bands, which can be realized through a cognitive radio system. During an agile communication between unlicensed users, a cognitive radio system must avoid collision with licensed users. Hence it should continuously observe the band of interest and report the presence of licensed user signals. This task is fulfilled by a vital part of a cognitive radio system, called the spectrum sensing core. Recently several techniques have been proposed for the spectrum sensing in literature. Some of them like matched filtering, cyclostationarity based detection are based on primary user signal features. However energy... 

Long Term Evolution (LTE) aims the peak data rates in excess of 300 Mb/s, which may appear to be challenging to achieve due to the existence of some blocks such as the turbo decoder. One efficient approach to achieve this throughput is by parallelizing the Log Maximum a Posteriori (MAP) algorithm in the turbo decoder. In fact, the interleaver is known to be a major challenging part of the turbo decoder due to its need to the parallel interleaved memory access. LTE uses Quadratic Permutation Polynomial (QPP) interleaver, which makes it suitable for the parallel decoding. In this thesis, first, we propose an efficient architecture for the QPP interleaver, called the Add-Compare-Select (ACS)...