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    Real-time simulation of the nonlinear visco-elastic deformations of soft tissues

    , Article International Journal of Computer Assisted Radiology and Surgery ; Volume 6, Issue 3 , 2011 , Pages 297-307 ; 18616410 (ISSN) Basafa, E ; Farahmand, F ; Sharif University of Technology
    Purpose: Mass-spring-damper (MSD) models are often used for real-time surgery simulation due to their fast response and fairly realistic deformation replication. An improved real time simulation model of soft tissue deformation due to a laparoscopic surgical indenter was developed and tested. Method: The mechanical realization of conventional MSD models was improved using nonlinear springs and nodal dampers, while their high computational efficiency was maintained using an adapted implicit integration algorithm. New practical algorithms for model parameter tuning, collision detection, and simulation were incorporated. Results: The model was able to replicate complex biological soft tissue... 

    A non-linear mass-spring model for more realistic and efficient simulation of soft tissues surgery

    , Article Medicine Meets Virtual Reality 16 - Parallel, Combinatorial, Convergent: NextMed by Design, MMVR 2008, Long Beach, CA, 30 January 2008 through 1 February 2008 ; Volume 132 , 2008 , Pages 23-25 ; 09269630 (ISSN); 9781586038229 (ISBN) Basafa, E ; Farahmand, F ; Vossoughi, G ; Sharif University of Technology
    IOS Press  2008
    An extension to the classical mass-spring model for more realistic simulation of soft tissues for surgery simulation was proposed. The conventional equations of mass-spring model were generalized for non-linear springs, and model parameters were tuned using experimental data. Results show that the proposed model is fast and interactive, and also demonstrate the typical nonlinear and visco-elastic behaviors of soft tissues well. © 2008 The authors. All rights reserved  

    Membrane Preparation For Organic Compounds Dehydration

    , M.Sc. Thesis Sharif University of Technology Basafa, Elahe (Author) ; Musavi, Abbas (Supervisor) ; Ramazani, Ahmad (Co-Advisor)
    Isopropanol purifying denotes dehydration of it to utilize in industries become important these days. Conventional process like distillation could not produce this product in high purity. Using membrane-based process, pervaporation, to dehydrate Isopropanol and other organic compound has been noticed in the last years. Among all type of membranes to dehydrate alcohols, poly (vinyl alcohol) is more effective due to its high hydrophilic characteristic. But it swallows in aqueous solutions and decrease its selectivity. To enhance structural and separation properties Chitosan, TiO2 and glurataldehyde added to polymeric membranes. Nine membranes have been made in this study that can be grouped in... 

    Design and implementation of series elastic actuators for a haptic laparoscopic device

    , Article Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009, 2 September 2009 through 6 September 2009, Minneapolis, MN ; 2009 , Pages 6054-6057 ; 9781424432967 (ISBN) Basafa, E ; Sheikholeslami, M ; Mirbagheri, A ; Farahmand, F ; Vossoughi, G. R ; Sharif University of Technology
    The design of a laparoscopic haptic device based on a 4-DOFs mechanism and Series Elastic Actuators (SEA) is described and the results of the theoretical and experimental examinations are presented. With a sufficient bandwidth and low impedance, the system provided a stable interaction with soft tissues, e.g., human liver, in virtual environments. ©2009 IEEE  

    Dose-dependent effects of nanoscale graphene oxide on reproduction capability of mammals

    , Article Carbon ; Volume 95 , December , 2015 , Pages 309-317 ; 00086223 (ISSN) Akhavan, O ; Ghaderi, E ; Hashemi, E ; Akbari, E ; Sharif University of Technology
    Elsevier Ltd  2015
    In vivo dose-dependent effects of nanoscale graphene oxide (NGO) sheets on reproduction capability of Balb/C mice were investigated. Biodistribution study of the NGO sheets (intravenously injected into male mice at dose of ∼2000 μg/mL or 4 mg/kg of body weight) showed a high graphene uptake in testis. Hence, in vivo effects of the NGO sheets on important characteristics of spermatozoa (including their viability, morphology, kinetics, DNA damage and chromosomal aberration) were evaluated. Significant in vivo effects was found at the injected concentrations ≥200 μg/mL after (e.g., ∼45% reduction in sperm viability and motility at 2000 μg/mL). Observation of remarkable DNA fragmentations and... 

    Accelerated differentiation of neural stem cells into neurons on ginseng-reduced graphene oxide sheets

    , Article Carbon ; Volume 66 , January , 2014 , Pages 395-406 Akhavan, O ; Ghaderi, E ; Abouei, E ; Hatamie, S ; Ghasemi, E ; Sharif University of Technology
    Asian red ginseng was used for green reduction of chemically exfoliated graphene oxide (GO) into reduced graphene oxide (rGO). The reduction level and electrical conductivity of the ginseng-rGO sheets were comparable to those of hydrazine-rGO ones. Reduction by ginseng resulted in repairing the sp 2 graphitic structure of the rGO, while hydrazine-rGO showed more defects and/or smaller aromatic domains. The ginseng-rGO sheets presented a better stability against aggregation than the hydrazine-rGO ones in an aqueous suspension. Whilst the hydrophobic hydrazine-rGO films exhibited no toxicity against human neural stem cells (hNSCs), the hydrophilic GO and ginseng-rGO films (as more... 

    Contested framings and policy controversies: Analysing biosafety policy-making in Iran

    , Article Science and Public Policy ; Volume 40, Issue 5 , 2013 , Pages 616-627 ; 03023427 (ISSN) Kashani, E. S ; Millstone, E ; Sharif University of Technology
    Vigorous debates have taken place within and between many countries about regulatory policy regimes covering the assessment and approval of genetically modified (GM) crops. In Iran, a very vigorous and hotly contested policy debate concerning legislation covering GM crops occurred between 2004 and 2009, but it was confined within government circles with almost no public discussion. This paper analyses the Iranian policy-making process in the period 2006-9. It explains how and why a stalemate arose in disputes between ministries and departments. The chosen analytical framework draws mainly on the regulation of technological risks and the analysis of public policy-making. It deploys the... 

    On the possible volumes of μ-way latin trades

    , Article Aequationes Mathematicae ; Volume 63, Issue 3 , 2002 , Pages 303-320 ; 00019054 (ISSN) Adams, P ; Billington, E. J ; Bryant, D. E ; Mahmoodian, E. S ; Sharif University of Technology
    Birkhauser Verlag Basel  2002
    A μ-way latin trade of volume s is a set of μ partial latin rectangles (of inconsequential size) containing exactly the same s filled cells, such that if cell (i, j) is filled, it contains a different entry in each of the μ partial latin rectangles, and such that row i in each of the μ partial latin rectangles contains, set-wise, the same symbols and column j, likewise. In this paper we show that all μ-way latin trades with sufficiently large volumes exist, and state some theorems on the non-existence of μ-way latin trades of certain volumes. We also find the set of possible volumes (that is, the volume spectrum) of μ-way latin trades for μ = 4 and 5. (The case μ = 2 was dealt with by Fu,... 

    The three-way intersection problem for latin squares

    , Article Discrete Mathematics ; Volume 243, Issue 1-3 , 2002 , Pages 1-19 ; 0012365X (ISSN) Adams, P ; Billington, E. J ; Bryant, D. E ; Mahmoodian, E. S ; Sharif University of Technology
    The set of integers k for which there exist three latin squares of order n having precisely k cells identical, with their remaining n2 -k cells different in all three latin squares, denoted by I3[n], is determined here for all orders n. In particular, it is shown that I3[n] = {0,.,n2 -15}U [n2 - 12,n2-9,n2], for n ≫8. ©2002 Eisevier Science B.V. All rights reserved  

    Integration of spatial fuzzy clustering with level set for segmentation of 2-D angiogram

    , Article IECBES 2014, Conference Proceedings - 2014 IEEE Conference on Biomedical Engineering and Sciences: "Miri, Where Engineering in Medicine and Biology and Humanity Meet", 8 December 2014 through 10 December 2014 ; December , 2015 , Pages 309-314 ; 9781479940844 (ISBN) Ghalehnovi, M ; Zahedi, E ; Fatemizadeh, E ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2015
    Coronary angiography is a vital instrument to detect the prevailing of vascular diseases, and accurate vascular segmentation acts a crucial role for proper quantitative analysis of the vascular tree morphological features. Level set methods are popular for segmenting the coronary arteries, but their performance is related to suitable start-up and optimum setting of regulating parameters, essentially done manually. This research presents a novel fuzzy level set procedure with the objective of segmentation of the coronary artery tree in 2-D X-ray angiography as automatically. It is clever to clearly develop from the early segmentation with spatial fuzzy grouping. The adjusting parameters of... 

    Deep relative attributes

    , Article 13th Asian Conference on Computer Vision, ACCV 2016, 20 November 2016 through 24 November 2016 ; Volume 10115 LNCS , 2017 , Pages 118-133 ; 03029743 (ISSN); 9783319541921 (ISBN) Souri, Y ; Noury, E ; Adeli, E ; Sharif University of Technology
    Springer Verlag  2017
    Visual attributes are great means of describing images or scenes, in a way both humans and computers understand. In order to establish a correspondence between images and to be able to compare the strength of each property between images, relative attributes were introduced. However, since their introduction, hand-crafted and engineered features were used to learn increasingly complex models for the problem of relative attributes. This limits the applicability of those methods for more realistic cases. We introduce a deep neural network architecture for the task of relative attribute prediction. A convolutional neural network (ConvNet) is adopted to learn the features by including an... 

    A public code for astrometric microlensing with contour integration

    , Article Monthly Notices of the Royal Astronomical Society ; Volume 505, Issue 1 , 2021 , Pages 126-135 ; 00358711 (ISSN) Bozza, V ; Khalouei, E ; Bachelet, E ; Sharif University of Technology
    Oxford University Press  2021
    We present the first public code for the calculation of the astrometric centroid shift occurring during microlensing events. The computation is based on the contour integration scheme and covers single and binary lensing of finite sources with arbitrary limb darkening profiles. This allows for general detailed investigations of the impact of finite source size in astrometric binary microlensing. The new code is embedded in version 3.0 of vbbinarylensing, which offers a powerful computational tool for extensive studies of microlensing data from current surveys and future space missions. © 2021 The Author(s) Published by Oxford University Press on behalf of Royal Astronomical Society  

    Toward electrically tunable, lithography-free, ultra-thin color filters covering the whole visible spectrum

    , Article Scientific Reports ; Volume 8, Issue 1 , 2018 ; 20452322 (ISSN) Aalizadeh, M ; Serebryannikov, A. E ; Khavasi, A ; Vandenbosch, G. A. E ; Ozbay, E ; Sharif University of Technology
    Nature Publishing Group  2018
    The possibility of real-time tuning of optical devices has attracted a lot of interest over the last decade. At the same time, coming up with simple lithography-free structures has always been a challenge in the design of large-area compatible devices. In this work, we present the concept and the sample design of an electrically tunable, lithography-free, ultra-thin transmission-mode color filter, the spectrum of which continuously covers the whole visible region. A simple Metal-Insulator-Metal (MIM) cavity configuration is used. It is shown that using the electro-optic dielectric material of 4-dimethyl-amino-N-methyl-4-stilbazoliumtosylate (DAST) as the dielectric layer in this... 

    A novel method for modeling the magnetizing yoke

    , Article Electromagnetics ; Volume 30, Issue 3 , 2010 , Pages 297-308 ; 02726343 (ISSN) Ravanbod, H ; Norouzi, E
    Magnetic flux leakage is the most widely used method for oil and gas pipeline non destructive testing. The saturation level of the sample under test has a significant effect on its efficiency; therefore, the magnetizing yoke requires an elaborate design. The finite element method is the conventional approach used for this purpose, but it is very time consuming. In this article, a neuro-fuzzy method is presented to model the behavior of the magnetizing yoke. Modeling a few different designs with the finite element method and using the results for training the neuro-fuzzy model eradicates the necessity of modeling a huge number of designs with the finite element method. The acquired... 

    On decomposing complete tripartite graphs into 5-cycles

    , Article Australasian Journal of Combinatorics ; Volume 54, Issue 2 , 2012 , Pages 289-301 ; 10344942 (ISSN) Alipour, S ; Mahmoodian, E. S ; Mollaahmadi, E ; Sharif University of Technology
    AJC  2012
    The problem of finding necessary and sufficient conditions to decompose a complete tripartite graph K(r, s, t) into 5-cycles was first considered by Mahmoodian and Mirzakhani (1995). They stated some necessary conditions and conjectured that these conditions are also sufficient. Since then, many cases of the problem have been solved by various authors; however the case when the partite sets r ≤ s ≤ t have odd and distinct sizes remains open. A necessary condition is t ≤ 3r. Billington and Cavenagh (2011) have shown that when r, s, and t are all odd and r ≤ s ≤ t ≤ κr, where κ ≈ 1.0806, then the conjectured necessary conditions for decomposing are also sufficient. We extend this result... 

    Ultra-sensitive detection of leukemia by graphene

    , Article Nanoscale ; Vol. 6, issue. 24 , Dec , 2014 , p. 14810-14819 Akhavan, O ; Ghaderi, E ; Hashemi, E ; Rahighi, R ; Sharif Universit of Technology
    Graphene oxide nanoplatelets (GONPs) with extremely sharp edges (lateral dimensions ∼20-200 nm and thicknesses <2 nm) were applied in extraction of the overexpressed guanine synthesized in the cytoplasm of leukemia cells. The blood serums containing the extracted guanine were used in differential pulse voltammetry (DPV) with reduced graphene oxide nanowall (rGONW) electrodes to develop fast and ultra-sensitive electrochemical detection of leukemia cells at leukemia fractions (LFs) of ∼10-11 (as the lower detection limit). The stability of the DPV signals obtained by oxidation of the extracted guanine on the rGONWs was studied after 20 cycles. Without the guanine extraction, the DPV peaks... 

    Specific picomolar detection of a breast cancer biomarker her-2/neu protein in serum: electrocatalytically amplified electroanalysis by the aptamer/peg-modified electrode

    , Article ChemElectroChem ; Volume 4, Issue 4 , 2017 , Pages 872-879 ; 21960216 (ISSN) Salimian, R ; Kékedy Nagy, L ; Ferapontova, E. E ; Sharif University of Technology
    Wiley-VCH Verlag  2017
    Specific and sensitive electroanalysis of blood-circulating protein cancer biomarkers is often complicated by interference from serum proteins nonspecifically adsorbing at the biosensing interface and masking specific reactions of interest. Here, we have developed an electrocatalytically amplified assay for specific and sensitive analysis of human epidermal growth factor receptor-2 (HER-2/neu, a protein cancer biomarker over-expressed in breast cancers) that allows us to avoid both the interference from bovine serum albumin (BSA) and electrocatalytic amplification of the signal stemming from the specific aptamer−HER-2/neu binding. A HER-2/neu-specific thiolated aptamer sequence was... 

    A two layer texture modeling based on curvelet transform and spiculated lesion filters for recognizing architectural distortion in mammograms

    , Article Middle East Conference on Biomedical Engineering, MECBME ; 17 - 20 February , 2014 , pp. 21-24 Khoubani, S ; Nadjar, H. S ; Fatemizadeh, E ; Mohammadi, E ; Sharif University of Technology
    This paper presents a two layer texture modeling method to recognize architectural distortion in mammograms. We propose a method that models a Gaussian mixture on the Curvelet coefficients and the outputs of Spiculated Lesion Filters. The Curvelet transform and the Spiculated Lesion Filters have been applied to extract textural features of mammograms in literature. However the key difference between this study and the previous ones is that in our approach, a Gaussian mixture models the textural features extracted by the Curvelet transform and the Spiculated Lesion Filters. The results of the current study are shown in the form of accuracy and the area under the receiver operating... 

    CFD-aided simulation of frost growth inside a narrow duct with uniform wall temperature variation

    , Article ASME 2014 12th International Conference on Nanochannels, Microchannels, and Minichannels, ICNMM 2014, Collocated with the ASME 2014 4th Joint US-European Fluids Engineering Division Summer Meeting ; 2014 ; ISBN: 9780791846278 Darbandi, M ; Asgari, E ; Hajikaram, M ; Schneider, G. E ; Sharif University of Technology
    In this paper, we study the frost formation and growth at the walls of a duct with uniform wall temperature variation. The simulation is performed for laminar flow regime considering suitable semi-empirical models incorporated with computational fluid dynamics (CFD) method. The frost growth is considered to be normal to the duct surface. Since the duct aspect ratio is high, we perform our simulations in two-dimensional zones. To simulate the frost layer properly, we solve both the energy and mass balance equations implementing some semi-empirical correlations on the frost side. At this stage, we suitably predict the required heat flux value at the solid boundary and the heat transfer... 

    Using the direct simulation Monte Carlo method to study the effect of wall temperature variation on gas mixing evolution through micro T-mixers

    , Article 11th International Energy Conversion Engineering Conference ; 2013 Darbandi, M ; Sabouri, M ; Lekzian, E ; Schneider, G. E ; Sharif University of Technology
    In this work, we study the gas mixing behavior in a micro T-mixer using the direct simulation Monte Carlo (DSMC) method. The gas mixing process is monitored through a T-mixer, which is fed by two different CO and N2 gases; flowing into the T-mixer through the upper and lower inlets. We investigate the effects of axial and lateral wall temperature gradients on the mixing evolution at different rarefaction levels. The achieved results show that any temperature difference between the channel walls would result in an increase in mixing length for the chosen wall temperature gradient ranges and the studies pressure cases. Our observations show that a positive temperature gradient toward the...