Sharif Digital Repository

Scheduling models are one of the main parts of computer-aided process design research in recent years. One of the novel applications of scheduling models is their usage for in-site utility management of a process plant. It is very common for huge process plants to provide their utility by themselves; therefore, they shall make decision on utility supply and demand simultaneously. This approach can be extended to other similar systems such as distributed generation networks. In fact, it is possible to consider a DG unit as an autonomous system which is responsible for its energy (heat and power) supply and demand. Of course, for achieving its reliability and dispatchability goals, it would... 

During the last decade, the importance of process development has persuaded researchers to propose a great number of optimization models on "production planning" and "production scheduling" for different productive processes. Although many scheduling and planning models are proposed in the past decade, there are few models that handle various applicable goals. In this paper the main objective is developing and extending the traditional scheduling formulations to accommodate optimization of utility (especially energy barriers) demands and supplies. In the context of optimization, the final formulation takes the form of a mixed-integer programming. For this purpose a mathematical model is... 

As the semiconductor industry advances to the deep sub-micron and nano technology points, the on-chip components are more prone to the defects during manufacturing and faults during system operation. Consequently, fault tolerant techniques are essential to improve the yield of modern complex chips. We propose a fault-tolerant routing algorithm that keeps the negative effect of faulty components on the NoC power and performance as low as possible. Targeting intermittent faults, we achieve fault tolerance by employing a simple and fast mechanism composed of two processes: NoC monitoring and route adaption. Experimental results show the effectiveness of the proposed technique, in that it offers... 

Since physiological and pathological processes occur at nano-environments, nanotechnology has considered as an efficient tool for designing of next generation specific biomolecules with enhanced pharmacodynamic and pharmacodynamic properties. In the current investigation, by control of the size and hydrodynamic volume at the nanoscale, for the first time, physicochemical and pharmacokinetic properties of an anti-VEGFA nanobody was remarkably improved by attachment of a Proline-Alanine-Serine (PAS) rich sequence. The results elucidated unexpected impressive effects of PAS sequence on physicochemical properties especially on size, hydrodynamics radius, and even solubility of nanobody. CD... 

Since physiological and pathological processes occur at nano-environments, nanotechnology has considered as an efficient tool for designing of next generation specific biomolecules with enhanced pharmacodynamic and pharmacodynamic properties. In the current investigation, by control of the size and hydrodynamic volume at the nanoscale, for the first time, physicochemical and pharmacokinetic properties of an anti-VEGFA nanobody was remarkably improved by attachment of a Proline-Alanine-Serine (PAS) rich sequence. The results elucidated unexpected impressive effects of PAS sequence on physicochemical properties especially on size, hydrodynamics radius, and even solubility of nanobody. CD...