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Removal of Pharmaceuticals from Polluted Water Using Carbon Nanotube-based Membranes Coated with Enzyme
, M.Sc. Thesis Sharif University of Technology ; Borghei, Mehdi (Supervisor) ; Ghobadi Nejad, Zahra (Co-Supervisor)
Abstract
Today, presence of micropollutants, including pharmaceutical compounds, in aquatic systems has turned into a major environmental challenge threatening the health of humans and many aquatic and terrestrial organisms. In the recent years, biodegradation of pharmaceuticals using enzymes, such as laccase, has been presented as a green method for eliminating these types of pollutants. Furthermore, regarding the improved stability and reusability of immobilized enzymes, these types of biocatalysts are suitable for industrial applications. Enzymatic membrane reactor is a promising method of enzymatic treatment and fabrication of a high-efficiency enzymatic membrane is a major step to begin this...
Synthesis and characterization of an antibacterial nanocomposite derived from two metal-organic frameworks for dye adsorption and antibacterial activity applications
, Article Chemical Engineering Research and Design ; Volume 198 , 2023 , Pages 34-45 ; 02638762 (ISSN) ; Ghobadi Nejad, Z ; Borghei, M ; Yaghmaei, S ; Sharif University of Technology
Institution of Chemical Engineers
2023
Abstract
In recent years, humans have been forced to create effective water treatment methods because of the increasing water contamination caused by various industrial activities. This study focuses on synthesizing a nanocomposite consisting of two metal-organic frameworks based on ZIF-8 with effective antibacterial characteristics and water-stable, highly porous UiO-66-NH2. After characterizing the synthesized nanocomposite, its application as (i) an adsorbent for methylene blue (MB) removal from a polluted aqueous environment and (ii) an antibacterial agent; was considered. The impact of different factors on the uptake of MB, including dye concentration, adsorption temperature, and the initial pH...
Pharmaceutical Active Compounds Removal by Immobilized Laccase on the Membrane
, M.Sc. Thesis Sharif University of Technology ; Borghei, Mehdi (Supervisor) ; Ghobadi Nejad, Zahra (Co-Supervisor)
Abstract
Pharmaceutical active compounds existence in the water would cause serious ecological risks and human health-related adverse effects which turn to environmental concern, therefore several studies have done to remove pharmaceutical active compounds efficiently. Carbamazepine (CBZ), a widely used psychiatric drug, is one of the most frequently detected compounds in the surface water and groundwater which is studies in the current study. Recently, biocatalytic degradation using ligninolytic enzymes such as laccase provides a promising approach for their removal from water and wastewater. In this work, carbamazepine removal by immobilized laccase on modified membrane by multi wall carbon nanotube...
Developing a Biomechanical Model of Lumbar Spine in Order to Evaluating the Behavior of Spine under Physiological and in Vitro Loading Conditions
, M.Sc. Thesis Sharif University of Technology ; Firozbakhsh, Keikhosrow (Supervisor) ; Parnianpour, Mohammad (Co-Advisor)
Abstract
In present study we are going to introduce a biomechanical model of lumbar spine with using finite element method and use it for evaluating the behavior of spine under different loading conditions.Spine as the main part of muskloskeletal system of human body is tolerating various forces during daily activities.So it's important to know about different approaches for studing the loading conditions wich is using for evaluating the behavior of lumbar implants. In other words in order to obtain correct outputs we need to simulate the real condition in the experiments. We can use biomechanical models in order to comparison the different approaches
Studying of Laccase Immobilization on Nanoparticles for Bisphenol A Removal
, M.Sc. Thesis Sharif University of Technology ; Borghei, Mehdi (Supervisor) ; Ghobadi Nejad, Zahra (Co-Supervisor)
Abstract
Bisphenol A is one of Endocrine Disturbing Chemicals. Enzymatic removal of bisphenol A is an interesting and green method. However, application of enzymes has been hampered due to lower operational stability and lots of difficulties in recovery and recycling. Enzyme immobilization can ba an innovative approach to circumvent these drawbacks. Laccase from Trametes hirsuta used for Bisphenol A removal. Firstly, magnetic nanoparticles were synthesized by coprecipitation method and aminofunctionalized by (3-aminopropyl)-mmethoxysilane. Subsequently, laccase was precipitated with i-propanol in the presence of aminofunctionalized nanoparticles and followed by addition of glutaraldehyde to the final...
Removal of bisphenol A in aqueous solution using magnetic cross-linked laccase aggregates from Trametes hirsuta
, Article Bioresource Technology ; Volume 306 , 2020 ; Ghobadi Nejad, Z ; Ghasemi, S ; Khafaji, M ; Borghei, S. M ; Sharif University of Technology
Elsevier Ltd
2020
Abstract
Enzymatic removal of Bisphenol A (BPA), acknowledged as an environmentally friendly approach, is a promising method to deal with hard degradable contaminants. However, the application of “enzymatic treatment” has been limited due to lower operational stability and practical difficulties associated with recovery and recycling. Enzyme immobilization is an innovative approach which circumvents these drawbacks. In this study, laccase from Trametes hirsuta was used for BPA removal. Amino-functionalized magnetic Fe3O4 nanoparticles were synthesized via the co-precipitation method followed by surface modification with (3-aminopropyl)trimethoxysilane (APTMS). The as-prepared nanoparticles were...
Pharmaceuticals removal by immobilized laccase on polyvinylidene fluoride nanocomposite with multi-walled carbon nanotubes
, Article Chemosphere ; Volume 263 , 2021 ; 00456535 (ISSN) ; Golgoli, M ; Ghobadi Nejad, Z ; Sadeghzadeh, S ; Borghei, S. M ; Sharif University of Technology
Elsevier Ltd
2021
Abstract
The presence of pharmaceutical micropollutants in water and wastewater is considered a serious environmental issue. To eliminate these pollutants, biodegradation of pharmaceuticals using enzymes such as laccase, is proposed as a green method. In this study, immobilized laccase was used for the removal of two model pharmaceutical compounds, carbamazepine and diclofenac. Polyvinylidene fluoride (PVDF) membrane modified with multi-walled carbon nanotubes (MWCNTs) were synthesized as a tailor-made support for enzyme immobilization. Covalently immobilized laccase from Trametes hirsuta exhibited remarkable activity and activity recovery of 4.47 U/cm2 and 38.31%, respectively. The results also...
Investigating the Biodegradability of Bioplastics Based on Polypropylene and Starch
, M.Sc. Thesis Sharif University of Technology ; Yaghmaei, Soheila (Supervisor) ; Ghobadi Nejad, Zahra (Supervisor) ; Borghei, Mehdi (Co-Supervisor)
Abstract
Due to the environmental crisis caused by the accumulation of plastics and disposable containers in nature, along with the significant challenges associated with their waste management, finding effective solutions to reduce plastic-related pollution was considered essential. One potential approach to address this issue is the use of indigenous microorganisms capable of plastic biodegradation, as well as the replacement of conventional plastics with biodegradable bioplastics that, owing to their degradable structures, reduced the environmental pollution load. In this study, the biodegradability of bio-based disposable containers was investigated through the isolation and purification of...
Synthesis, Characterization and Applications of Antibacterial Metal-Organic Framework Nanocomposites for Water Remediation
, M.Sc. Thesis Sharif University of Technology ; Borghei, Mehdi (Supervisor) ; Yaghmaei, Soheila (Supervisor) ; Ghobadi Nejad, Zahra (Co-Supervisor)
Abstract
Contaminants in drinking water, including microbial contaminants, have a great impact on the health of people in the community and can seriously threaten public health. In recent years, diseases caused by pathogenic bacteria due to the consumption of contaminated water have led to many deaths. As a result, water treatment has been one of the most important human concerns. Among the new water treatment technologies, metal-organic(MOF) frameworks are a new generation of porous materials that have properties such as high surface area, water stability and functionality due to their dual structure. As a result, they are widely used today in various scientific fields, including water purification....
Kinetics of organic removal in fixed-bed aerobic biological reactor
, Article Bioresource Technology ; Volume 99, Issue 5 , 2008 , Pages 1118-1124 ; 09608524 (ISSN) ; Sharbatmaleki, M ; Pourrezaie, P ; Borghei, G ; Sharif University of Technology
2008
Abstract
The process kinetics of a lab-scale upflow aerobic immobilized biomass (UAIB) reactor using simulated sugar-manufacturing wastewater as feed was investigated. The experimental unit consisted of a 22 l reactor filled with high porosity pumice stone. The UAIB reactor was tested under different organic loads and different hydraulic retention times (HRT) and the substrate loading removal rate was compared with prediction of Stover-Kincannon model, second-order model and the first order substrate removal model. After obtaining steady-state conditions, organic loading rate was increased from 750 to 4500 g COD/m3 day to resemble wastewater from sugar production lines, and hydraulic retention time...
A Counting Formula for the Kervaire Semi-Characteristic
, M.Sc. Thesis Sharif University of Technology ; Esfahani Zadeh, Mustafa (Supervisor)
Abstract
Similar to the classical Poincare-Hopf index formula for the Euler characteristic, Zhang gave a counting formula for the Kervaire semi-characteristic of a 4q+1 manifold. We first study Witten deformation techniques in the proof of the Poincare-Hopf formula. Then we will represent Zhang’s formula which uses similar analysis. Both these formulas establish a connection between topological and geometrical data on a manifold. Both proofs will be analytical. Index theory will play the ’bridge’ between the topology and analysis. We begin with an analytic interpretation of the topologically defined quantities as indices of differential operators. We deform the operators with respect to appropriate...
Load Shedding in Microgrids to preserve System Stability In The Islanded Operation Mode
, M.Sc. Thesis Sharif University of Technology ; Parniani, Mustafa (Supervisor)
Abstract
In the near future, it is expected that the microgrids become widespreed due to issues such as reliability, increased penetration of renewable energy sources and distributed generation, environmental concerns and shortage of fossil fuels. Different control methods have been suggested to regulate the frequency and voltage of the system so that these quantities remain in their permissible range upon islanding and in the islanded operation mode. However, in emergency conditions, such as shortage of generated power compared to the load of microgrid, frequency or voltage reduction occures due to imbalance. In this situation, it is invitable to shed extra load to maintain the stability and...
Improving self-care and health literacy in hemodialysis patients: Using software engineering
, Article Proceedings - 2012 7th International Conference on Computing and Convergence Technology (ICCIT, ICEI and ICACT), ICCCT 2012, 3 December 2012 through 5 December 2012 ; December , 2012 , Pages 317-320 ; 9788994364216 (ISBN) ; Edalat-Nejad, M ; Edalat-Nejad, N ; Sharif University of Technology
2012
Abstract
The use of Computer Science in order to categorize and store information, improve diagnostic and therapeutic procedures, patient education and the training of a skilled labor force, has taken important steps and there are constantly new developments in this area
The Correlation between Science & Abrahamic Religions (Emphasizing on Evolutionary Biology & Islam)
, Ph.D. Dissertation Sharif University of Technology ; Tagavi, Mustafa (Supervisor) ; Miandari, Hassan (Supervisor)
Abstract
While the science–religion debate on human creation has been widely explored in the Muslim world، Iranian Muslim opinions have been missed in the mainstream literature. To see whether they follow the lead of the majority of Muslim thinkers or not، here is an overview of the Qur’anic Perspective of Iranian Muslim Scholars. After reviewing the previously categorized approaches of Muslims encountering evolution mentioned in the literature، this thesis will survey the Qur’anic verses related to the biological creation of man with the “scientific-lexical” method of all possible states. Afterward، the views of the most-cited Iranian scholars، such as Saḥābī، Ṭabāṭabā’ī، Muṭahharī، and Jawādī، will...
Introduction of clinical, simulation-based software for medical sciences teachings
, Article Procedia Engineering ; Volume 29 , 2012 , Pages 43-47 ; 18777058 (ISSN) ; Edalat-Nejad, M ; Edalat Nejad, N ; Edalatnejad, M ; Sharif University of Technology
2012
Abstract
Simulation is the gold standard for training in aviation and trauma medicine. Now it is available for diseases diagnosis and treatment. With simulation, clinicians can practice their art in a realistic, consequence free environment, combining both theory and practice in a comprehensive program. Method and materials - In the virtual clinical environment of "VPsoft mentor" software, the practitioner reviews a patient's history, orders laboratory tests and procedures, interprets findings, renders diagnoses, and prescribes medication. Every diagnostic or treatment decision the clinician makes for the patient is analyzed by E-mentor, providing instant feedback.Results - This software have been...
Jet impact geometry and plunge pool dimensions effects on dynamic pressures at pool sidewalls
, Article Canadian Journal of Civil Engineering ; Volume 35, Issue 4 , 2008 , Pages 408-417 ; 03151468 (ISSN) ; Zarnani, P ; Sharif University of Technology
2008
Abstract
A plunge pool is one of the energy dissipater structures for high head dams, which ensures stability of the dam under extreme hydrodynamic pressure, due to falling jet impacts. The excess energy of the jet is dissipated, together with significant impact pressure exerted on the floor and pool walls. Thus, appropriate assessment of jet dynamic characteristics in the plunge pool is essential. This research presents experimental results focusing on. the distribution of mean and extreme pressure fluctuations on the sidewalls, due to circular and rectangular plunging jets, and the effects of pool dimension, especially in narrow valleys. The experimental variables are discharge, geometry of jet,...
Ground Water Denitrification by Packed Bed Bioreactor With KMT Packing
, M.Sc. Thesis Sharif University of Technology ; Borghei, Mehdi (Supervisor)
Abstract
In this study biological denitrification method by moving bed biofilm reactor is investigated. The main advantage of MBBR reactor is due to their capacity for high removal rates and low operational problems such as clogging. Two MBBRs in series with 3 liter volume each, were designed in experimental set up and used in this research. Nitrification reactor worked under aerobic conditions and denitrification reactor operated under anaerobic conditions. Methanol was used as carbon source in the reactors throughout the study. Fifty percent of each reactor volume was occupied with KMT1 packing. To finding the optimum nitrate loading rate, the concentration of ammonium and nitrate were changed from...
Controlling Local Scour Due to Hydraulic Jump Using Oblique Buried Plates
,
M.Sc. Thesis
Sharif University of Technology
;
Borghei, Mahmood
(Supervisor)
Abstract
Local scouring at the downstream of sluice gates in the erosive beds is one of the main concerns of hydraulic engineers because of the significant damage that it can cause to the hydraulic structures. It is important to control the local scour depth at downstream of hydraulic structures to ensure safety operation of these systems. Many researchers have conducted various studies to predict the maximum depth and diameter of scour hole and develop new methods in order to control this phenomenon. One way to overcome this problem is the use of apron, or non-erosive bed. In order to shorten the apron length or decrease the effect of the...
Optimization of Oily and Biological Sludge Digestion and Dewatering Process for Arak Refinery Wastewater Treatment Plant
, M.Sc. Thesis Sharif University of Technology ; Borghei, Mehdi (Supervisor)
Abstract
Different strategies for the treatment and disposal of petroleum and biological sludge found in the treatment and reuse unit of Arak Petroleum Refinery have been studied in the present study. To this end, the resources found in the literature corresponding to the different fields of sludge treatment were studied and a summary of them which was required by this research was mentioned in the thesis. Considering the problems bound to the wastewater treatment unit of this refinery plant and the previous studies, two completely separate strategies were devised. The first one concerns petroleum and biological sludge being produced continuously. The method of aerobic fixation of petroleum sludge by...
Biological Removal of Nutrients in MBBR Reactors, Using Bardenpho Process Principle
, M.Sc. Thesis Sharif University of Technology ; Borghei, Mehdi (Supervisor)
Abstract
Given that the most polluting industries in the country there. A suitable treatment system for degradation of these compounds is necessary unless unexpected effect on environment will occur.Moving Bed Biofilm Reactor (MBBR) was developed to adopt the best features of the activated sludge process as well as those of the biofilter processes. MBBR has biomass growth on carriers that move freely in the water volume of the reactor. High surface area of carriers make a good condition for biomass attached growth. This system has had good operation in the urban and some industrial wastewaters.In this study, four reactor volume of approximately 16 litr and 6, respectively, in the aerobic, anoxic...