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This paper reviews the applications of experimental design to optimize some analytical chemistry techniques such as extraction, chromatography separation, capillary electrophoresis, spectroscopy, and electroanalytical methods  

This paper reviews the main concepts of experimental design applicable to the optimization of analytical chemistry techniques. The critical steps and tools for screening, including Plackett-Burman, factorial and fractional factorial designs, and response surface methodology such as central composite, Box-Behnken, and Doehlert designs, are discussed. Some useful routines are also presented for performing the procedures  

Volatile components of saffron from different regions of Iran were extracted by ultrasonic-assisted solvent extraction (USE) and were analyzed by gas chromatography-mass spectrometry (GC-MS). Self-modeling curve resolution (SMCR) was proposed for resolving the co-eluted GC-MS peak clusters into pure chromatograms and mass spectra. Multivariate curve resolution-objective function minimization (MCR-FMIN) and multivariate curve resolution-alternating least square (MCR-ALS) were successfully used for this purpose. The accuracy of the qualitative and quantitative results was improved considerably using SMCR techniques. Comparison of the results of saffron from different regions of Iran showed... 

The volatile components of Iranian saffron were extracted using ultrasonic solvent extraction (USE) technique and then were separated and detected by gas chromatography-mass spectrometry (GC-MS). Variables affecting the extraction procedure were screened by using a 25-1 fractional factorial design and among them; sample amount, solvent volume, solvent ratio and extraction time were optimized by applying a rotatable central composite design (CCD). The optimum values of factors were: 2.38 g sample, 29.04 mL solvent, 69.23% MeOH solvent ratio and 71.8 min for the extraction time. Forty constituents were identified for Iranian saffron by GC-MS representing 90% of the total peak area. The major... 

The properties of metallic nanorods vary due to changes in their composition, size and shape, which all depend on the aspect ratio of the nanorods. This work focuses on the optimization of the aspect ratio of silver nanorods using response surface methodology (RSM). Seed-mediated approach, which is the newest method with less difficulty, has been used for the synthesis of silver nanorods. First, silver ions were reduced with sodium borohydride in the presence of sodium citrate dehydrate, as stabilizer. Then, the prepared seeds were added to a solution containing more metal salts, a weak reducing agent (ascorbic acid) and a rod-like micellar template (cetyltrimethylammonium bromide, CTAB).... 

The current study presents an application of near infrared spectroscopy for identification and quantification of the fraudulent addition of barley in roasted and ground coffee samples. Nine different types of coffee including pure Arabica, Robusta and mixtures of them at different roasting degrees were blended with four types of barley. The blending degrees were between 2 and 20 wt% of barley. D-optimal design was applied to select 100 and 30 experiments to be used as calibration and test set, respectively. Partial least squares regression (PLS) was employed to build the models aimed at predicting the amounts of barley in coffee samples. In order to obtain simplified models, taking into... 

An analytic expression for energy and angular dependence of a secondary charged lepton in the decay of a polarized top quark with anomalous tWb couplings in the presence of all anomalous couplings are derived. The angular distribution of the b-quark is derived as well. It is presented that the charged lepton spin correlation coefficient is not very sensitive to the anomalous couplings. However, the b-quark spin correlation coefficient is sensitive to anomalous couplings and could be used as a powerful tool in the search for non-SM coupling. © 2007 IOP Publishing Ltd  

In this paper we study the noncommutative effects to the lepton spectrum from the decay of a polarized top quark. It is shown that the lowest contribution comes from the quadratic terms of the noncommutative parameter. The deviations from the standard model are significant for small values of the noncommutative characteristic scale. However, the charged lepton spin correlation coefficient has a remarkable deviation from the standard model from very low values of the noncommutative characteristic scale to 1 TeV. © 2006 The American Physical Society  

In this article, two adaptive model predictive controllers (AMPC) are applied to regulate the blood glucose in type 1 diabetic patients. The first controller is constructed based on a linear model, while the second one is designed by using a nonlinear Hammerstein model. The adaptive version of these control schemes is considered to make them more robust against model mismatches and external disturbances. The least squares method with forgetting factor is used to update the model parameters. For simulation study, two well-known mathematical models namely, Puckett and Hovorka which describe the dynamical behavior of patient's body have been selected. The performances and robustness of the... 

The anomalous top quark interactions with gluon (tug, tcg) allow the production of single top quarks at the Large Hadron Collider (LHC). Using the angular distribution of the charged lepton from the W boson in the top decay, we show that with the data of 10 fb-1 of integrated luminosity and in the collisions with the center of mass energy of 14TeV, the anomalous up and charm quarks coupling parameters κu,c/Λ can be measured down to 0.005 and 0.007 TeV-1, respectively  

In this study, a novel type of passive energy dissipation device called a Telescopic Lead Yielding Damper (TLYD) is proposed and analyzed. This device comprises co-axial steel cylinders and lead rings, such that these rings act as shear locks between the steel cylinders. TLYDs dissipate energy through the plastic shear deformation of lead metal. The telescopic mechanism used in TLYDs allows these small-sized dampers to tolerate large axial displacements with low fatigue. For each telescopic level, a yield plateau is added to the hysteresis behavior of TLYD devices. Each yield plateau resists a different performance level, namely design-based and maximum credible earthquakes. Seven... 

This work introduces a new gradient fiber coating for microextraction of chlorobenzenes. Nanoclusters of organoclay-Cu(II) on a copper wire were fabricated by wireless electrofunctionalization. The resultant gradient coatings are more robust, and thermally and mechanically stable. Wireless electrofunctionalization was carried out in a bipolar cell under a constant deposition potential and using an ethanolic electrolyte solution containing stearic acid and montmorillonite. Stearic acid acts as an inexpensive and green coating while montmorillonite acts as a modifier to impart thermal stability. The gradient morphology of the nanoclusters was investigated by scanning electron microscopy,... 

Microalgae have been remarkably taken into account due to their wide applications in the biopharmaceutical, nutraceutical and bio-energy fields. However, contamination of microalgae with bacteria still appears to be a concern, adversely impacting products’ quality and process efficiency. Microalgae decontamination with conventional techniques is usually expensive and time-consuming. Moreover, damage to microalgae cells is highly possible. Asymmetric contraction-expansion microchannels (Asym-CEMCs) are promising passive microfluidic devices that can overcome conventional techniques' drawbacks with their standing-out features. However, the flexibility of Asym-CEMCs performance arising from... 

Switched Reluctance Motors (SRMs) are widely used in high-speed and low voltage applications because of their attractive features such as robustness and simplicity. No winding on the rotor of this type of motors allows reaching high speed which is desired for many applications. Drive circuits of SRMs also play an important role in their performance and operation. In this paper, a new bifilar drive circuit for this type of motors has been proposed. This novel configuration has been tested and investigated by PSIM software. Results show that the new bifilar drive circuit highly reduces the voltage stresses on semiconductor switches, and also considerably reduces the switching losses which are... 

The gas chromatography retention indices of 100 different components of essential oils, on three columns with stationary phases of different polarities, were used to develop robust quantitative structure-retention relationship (QSRR) models. Two linear models with only one variable, i.e. solvation entropy, were developed, which explain 95 and 94% of variances of the test set for dimethyl silicone and dimethyl silicone with 5% phenyl group columns, respectively. These models are extremely simple and easy to interpret, but they show higher errors compared with more robust models such as partial least square (PLS) and ridge regressions. For the third column (polyethylene glycol (PEG)), 24... 

This contribution focuses on the use of ladder particle swarm optimisation (LPSO) on modelling of oxadiazole- and triazolesubstituted naphthyridines as human immunodeficiency virus-1 integrase inhibitors. Artificial neural network (ANN) and Monte Carlo cross-validation techniques were combined with LPSO to develop a quantitative structure-activity relationship model. The techniques of LPSO, ANN and sample set partitioning based on joint x-y distances were applied as feature selection, mapping and model evaluation, respectively. The variables selected by LPSO were used as inputs of Bayesian regularisation ANN. The statistical parameters of correlation of deterministic, R2, and... 

In this paper, an analytical performance model for adaptive wormhole routing in the hypercube-based optical transpose interconnection system (OTIS-hypercube) is proposed and validated. Using this model, the performance merits of the OTIS-hypercube are discussed. We also compare the performance of the OTIS-hypercube with that of equivalent hypercube network under different implementation constraints. Compared to pure simulation results, the presented model can serve as a more appropriate and compact method to display the performance characteristics of OTIS-hypercube networks. © 2007 Elsevier Inc. All rights reserved  

Regarding the increasing number of electrical devices in the smart homes that leads to increase in total electricity consumption and cost, it is essential to use energy management methods to reduce the electricity cost. However, this can cause resident's dissatisfaction. Hence, it is important to define a method in which cost and dissatisfaction be optimized simultaneously. Among different services, an electric vehicle is the one that can be used as an energy storage system, so it can reduce the daily cost despite of increasing the total energy consumption. In this paper, we study the effect of the EV on the cost and dissatisfaction in our proposed method. © 2018 IEEE