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    Smart micro/nano-robotic systems for gene delivery

    , Article Current Gene Therapy ; Volume 17, Issue 2 , 2017 , Pages 73-79 ; 15665232 (ISSN) Pedram, A ; Nejat Pishkenari, H ; Sharif University of Technology
    Bentham Science Publishers B.V  2017
    Abstract
    Background: Small scale robotics have attracted growing attention for the prospect of targeting and accessing cell-sized sites, necessary for high precision biomedical applications and drug/gene delivery. The loss of controlled gene therapy, inducing systemic side effects and reduced therapeutic efficiency, can be settled utilizing these intelligent carriers. Methods: Newly proposed solutions for the main challenges of control, power supplying, gene release and final carrier extraction/degradation have shifted these smart miniature robots to the point of being employed for practical applications of transferring oligonucleotides (pDNA, siRNA, mRNA, etc.) in near future. Conclusion: In this... 

    The Status of Scientific-Technological Instruments from the Point of View of Scientific Anti-Realism

    , M.Sc. Thesis Sharif University of Technology Pedram, Ali (Author) ; Akbari, Javad (Supervisor)
    Abstract
    One of the main arguments between scientific realists and scientific anti-realists is about observability. As a prominent anti-realist, van Fraassen and his theory of constructive empiricism and his views on observability and the use of scientific instruments, have been the subject of many debates. He believes that observation is the sole path to knowledge and observation is only possible through unaided human eye, so seeing through scientific instruments like microscopes does not count as observation, therefore the information gained from these procedures are not necessarily true.This thesis not only examines van Fraassen’s outlooks on the matter, but also examines his opponents’ view and... 

    A Fabrication Method of Neutrally-buoyant Magnetic Micro-robot to Improve Its Motion Control

    , M.Sc. Thesis Sharif University of Technology Pedram, Alireza (Author) ; Nejat Pishkenari, Hossein (Supervisor)
    Abstract
    Micro-robotics is one of the currently emerging technologies which has attracted attentions for its probable applications in different fields including biotechnology, diagnosis and treatment in medical engineering as well as general studies in micro-scale science and engineering. Magnetic micro-robotics is considered as the most promising group, primarily due to the biocompatibility of magnetic fields and advances in electronic circuits to produce and control such fields. One critical point in utilizing these robots is their high density in comparison with the working fluid and their tendency to sink. In this thesis, a method to fabricate buoyant magnetic robots has been proposed based on... 

    Optimal controller design for 3D manipulation of buoyant magnetic microrobots via constrained linear quadratic regulation approach

    , Article Journal of Micro-Bio Robotics ; Volume 15, Issue 2 , 2019 , Pages 105-117 ; 21946418 (ISSN) Pedram, A ; Nejat Pishkenari, H ; Sitti, M ; Sharif University of Technology
    Springer  2019
    Abstract
    We consider magnetic actuation and control of a spherical neutrally buoyant magnetic microrobot via magnetic coil setups and seek to design an optimal controller to reduce the required energy and coils’ currents. We showed that in currently employed setups, where the actuation frequency is few tens of Hertz, the nonlinear dynamics of the system can be well approximated by a set of linear constrained ones. The approximated model is obtained by consciously overlooking the rotational dynamics and the inertia terms in translational dynamics. We acquired the linear quadratic regulation (LQR) controller for the approximated model which is a constrained time-varying system. Finally, 3D manipulation... 

    A physicochemical evaluation of modified HZSM-5 catalyst utilized for production of dimethyl ether from methanol

    , Article Petroleum Science and Technology ; Vol. 32, issue. 8 , Feb , 2014 , pp. 904-911 ; ISSN: 10916466 Pedram, M. Z ; Kazemeini, M ; Fattahi, M ; Amjadian, A ; Sharif University of Technology
    2014
    Abstract
    A number of HZSM-5 catalysts modified with 5 wt% Mg, Na, Zr, and Al as well as others modified with 5-60 wt% Zn prepared by wet impregnation. These materials were characterized by the NH3-TPD, XRF, and XRD analyses and tested in a slurry reactor to determine their activities in dehydration of methanol solution in kerosene. Reactions were carried out at 230°C and 19 bar for 4 h of residence time in the reactor. Results showed that in the first series, the catalyst modified with Zr and in the second series, the one modified with 10 wt% Zn led to the highest methanol conversion. It was deduced that elimination of strong acid sites and partial replacement of active cations in the HZSM-5 zeolite... 

    Analysis and fast estimation of energy consumption in template based QDI asynchronous circuits

    , Article 2007 International Symposium on Integrated Circuits, ISIC, Singapore, 26 September 2007 through 28 September 2007 ; 2007 , Pages 445-448 ; 1424407974 (ISBN); 9781424407972 (ISBN) Ghavami, B ; Mirza Aghatabar, M ; Pedram, H ; Hessabi, S ; Sharif University of Technology
    2007
    Abstract
    In this paper we analyses the energy consumption of well known family of asynchronous circuits and present a new methodology for energy estimation of these circuits at intermediate-level of abstraction. Energy estimation is performed by simulating the intermediate format of the design. The number of Read and Write accesses on the ports of the concurrent processes are counted by analyzing the conditional and computational portion during the simulation which is the base of our estimation methodology. Our proposed power estimation scheme is faster than usual post-synthesis power estimation by an order of 9, while the estimated power resides in a boundary of 11% total imprecision. © 2007 IEEE  

    An empirical investigation of mesh and torus NoC topologies under different routing algorithms and traffic models

    , Article 10th Euromicro Conference on Digital System Design Architectures, Methods and Tools, DSD 2007, Lubeck, 29 August 2007 through 31 August 2007 ; October , 2007 , Pages 19-26 ; 076952978X (ISBN); 9780769529783 (ISBN) Mirza Aghatabar, M ; Koohi, S ; Hessabi, S ; Pedram, M ; Sharif University of Technology
    2007
    Abstract
    NoC is an efficient on-chip communication architecture for SoC architectures. It enables integration of a large number of computational and storage blocks on a single chip. NoCs have tackled the SoCs disadvantages and are scalable. In this paper, we compare two popular NoC topologies, i.e., mesh and torus, in terms of different figures of merit e.g., latency, power consumption, and power/throughput ratio under different routing algorithms and two common traffic models, uniform and hotspot. To the best of our knowledge, this is the first effort in comparing mesh and torus topologies under different routing algorithms and traffic models with respect to their performance and power consumption.... 

    Comparison of several sparse recovery methods for low rank matrices with random samples

    , Article 2016 8th International Symposium on Telecommunications, IST 2016, 27 September 2016 through 29 September 2016 ; 2017 , Pages 191-195 ; 9781509034345 (ISBN) Esmaeili, A ; Marvasti, F ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2017
    Abstract
    In this paper, we will investigate the efficacy of IMAT (Iterative Method of Adaptive Thresholding) in recovering the sparse signal (parameters) for linear models with random missing data. Sparse recovery rises in compressed sensing and machine learning problems and has various applications necessitating viable reconstruction methods specifically when we work with big data. This paper will mainly focus on comparing the power of Iterative Method of Adaptive Thresholding (IMAT) in reconstruction of the desired sparse signal with that of LASSO. Additionally, we will assume the model has random missing information. Missing data has been recently of interest in big data and machine learning... 

    A novel approach to quantized matrix completion using huber loss measure

    , Article IEEE Signal Processing Letters ; Volume 26, Issue 2 , 2019 , Pages 337-341 ; 10709908 (ISSN) Esmaeili, A ; Marvasti, F ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2019
    Abstract
    In this paper, we introduce a novel and robust approach to quantized matrix completion. First, we propose a rank minimization problem with constraints induced by quantization bounds. Next, we form an unconstrained optimization problem by regularizing the rank function with Huber loss. Huber loss is leveraged to control the violation from quantization bounds due to two properties: first, it is differentiable; and second, it is less sensitive to outliers than the quadratic loss. A smooth rank approximation is utilized to endorse lower rank on the genuine data matrix. Thus, an unconstrained optimization problem with differentiable objective function is obtained allowing us to advantage from... 

    Robust & nonlinear control of an ultra-supercritical coal fired once-through boiler-turbine unit in order to optimize the uncertain problem

    , Article Energy ; Volume 282 , 2023 ; 03605442 (ISSN) Esmaeili, M ; Moradi, H ; Sharif University of Technology
    Elsevier Ltd  2023
    Abstract
    The ultra-supercritical once-through boiler (OTB) unit is an advanced power generation technology with high plant efficiency and low emissions. However, it is difficult to realize a coordinate control for the ultra-supercritical OTB unit to achieve the fast and stable dynamic response during the load tracking and grid frequency disturbances and in the presence of unavoidable uncertainties. In this paper, an accurate grey box multivariable coupled nonlinear model of an ultra-supercritical boiler-turbine unit is considered. Steam pressure at throttle valve, specific enthalpy in separator and active power are adjusted at desired values by manipulation of the fuel rate command, feedwater rate... 

    Achievable Rates in CDMA and OFDM Based Optical Networks

    , M.Sc. Thesis Sharif University of Technology Esmaeili, Hossein (Author) ; Salehi, Jawad (Supervisor)
    Abstract
    Regarding the increasing trend of network costumers and services, requirement of high-speed and high quality seems to be inevitable. Therefor much effort has been put to issue the problem properly in recent years. Optical fiber networks are attending more attention and optical fiber channels are dominating the world of networking and data. Applying new methods such as CDMA and OFDM raise the issue of maximum achievable rate and quality of these systems.These include the main concentration of this project. First, optical channels are modeled.Then, applying OFDM and CDMA methods, lower and upper bound of channel capacity will be determined  

    Fabrication and Optical Response Characterization of High-Tc Superconductor Josephson Junction

    , M.Sc. Thesis Sharif University of Technology Esmaeili, Mohaddeseh (Author) ; Fardmanesh, Mehdi (Supervisor)
    Abstract
    Design of superconducting material based wide band radiation detectors has recently been attractive. Interesting features of detectors, which are based on Josephson Junctions such as high sensitivity in a wide range of frequencies and low power consumption, potentially have many advantages over other semiconductor-based photo-detectors. According to variety of applications of high-Tc superconductors, particularly YBCO, and significant progress in manufacturing of thin films and Josephson junctions, this thesis mainly focuses on investigation of radiation effects on I-V characteristics of high-Tc step-edge Josephson junctions experimentally. The current-voltage characteristics of fabricated... 

    Defining Sets in Total and Edge Coloring of Graphs

    , M.Sc. Thesis Sharif University of Technology Esmaeili, Mehdi (Author) ; Mahmoodian, Ebadollah (Supervisor)
    Abstract
    Critical sets and defining sets in combinatorics have been attended by mathematics fans. These subjects have been debated since 1997 and a lot of researches have been done about them and a lot of articles have been published. But number of unsolved questions might be more than answered questions. In these years critical sets for Latin square and defining sets for vertex coloring have been attended and also enough researches about issues related to defining sets for edge coloring and total coloring have not been done. For these reasons we focus on these issues in this thesis. Issues like defining sets for edge coloring and total coloring in complete graphs, generalized Petersen graphs and also... 

    Wear Behavior of the Nanostructured A356 Aluminum Alloy Induced by Severe Shot Peening

    , M.Sc. Thesis Sharif University of Technology Esmaeili, Mohammadamin (Author) ; Farrahi, Gholamhossein (Supervisor)
    Abstract
    Wear is the most important cause of surface damage occurs by direct contact of surfaces. Increasing the quality and strength of surface against different kinds of destructive phenomena is significant in manufacturing of mechanical parts. Surface nanocrystallisation can improve the surface protection against wear and can be done by lazer beam and shot peening. In this investigation by sever shot peening process the surface of A356 Aluminium alloy transforms to nanocrystal structure. The dry sliding wear and friction behaviors of A356 Aluminum were evaluated using a pin-on-disk apparatus at ambient conditions. The stationary diameter of 5mm stainless steel pin produced a wear track (scar) on... 

    Feasibility Study of Services of Metal 3D Printer in Iran's Industry

    , M.Sc. Thesis Sharif University of Technology Esmaeili, Ali (Author) ; Mostafavi, Mostafa (Supervisor)
    Abstract
    One of the best ways to overcome the weaknesses of technology services in different industries is right technology transfer with feasibility in the country. 3D painters have been recently widely used industrially in different countries. The 3D printer is one of the new emerging technologies, enabling the production of every 3D objects with any complexity. 3D printing has provided the possibility of producing, in fastest, more economics and regardless of those complexities. By transfer of this kind of technology and proper management, a huge transformation can created in all industries and factories. To do this, there are several technologies of 3D printing, that each of them used in various... 

    Robust and Nonlinear Control of the Boiler-Turbine Unit Performance in a Coal Fired Ultra-Supercritical Once Through Boiler Power Plant in Order to Optimize the Uncertain Problem

    , M.Sc. Thesis Sharif University of Technology Esmaeili, Mohammad (Author) ; Moradi, Hamed (Supervisor)
    Abstract
    Nowadays electricity power has a key role in developing various aspects of the world. The great importance of fossil fuel power plants come from their large contribution in electricity power generation. Among the different fossil fuel power generation technologies, supercritical power plants have great advantages. They are an advanced power generation technology with high plant efficiency, high coal utilization and low emission. Their complexity and existing many unavoidable uncertainty sources in their dynamic such as changes of ambient temperature, climate condition and wear of components make their control challenging. To overcome mentioned problems and achieving a good performance, a... 

    Philosophy of Literature: Post-Structuralists and Aristotelians on Literature and its Moral Implications in the Contemporary Times

    , M.Sc. Thesis Sharif University of Technology Esmaeili, Jaber (Author) ; Azadegan, Ebrahim (Supervisor)
    Abstract
    The relationship between art and philosophy has been disputed for a long time and its history goes back to the ancient Greece. The dominant literary form at that time was poetry or tragedy, which are the first side of this relationship. On the other side was philosophical ethics. Plato and Aristotle are the main protagonists in this quarrel, which is known as the "Ancient Quarrel". I will first examine this quarrel and follow its different forms in the modern era, in which Hegel plays a prominent role by proposing the "end of art" thesis. By examining the criticisms made to this thesis, I will make clear the context in which the contemporary defenses that I explained in the following... 

    Optimal Energy Management of Microgrids using Quantum Teaching Learning Based Algorithm

    , M.Sc. Thesis Sharif University of Technology Esmaeili, Zahra (Author) ; Hosseini, Hamid (Supervisor)
    Abstract
    The most important challenge in microgrids is the coordination of distributed energy resources (DERs), due to the existence of several DERs with fugacious characteristics. Also, energy management in the microgrid is very important because there may be conflicting needs or poor communication between different elements of the microgrid. In this work, a robust frame associated with a quantum version of the Teaching-Learning-Based Optimization (quantum TLBO) algorithm is proposed for the first time to the microgrid optimal energy management problem. Uncertainties in the load and in the output power of renewable energy sources are modeled using robust optimization (RO). The operation cost of the... 

    Information Retrieval from Incomplete Observations

    , Ph.D. Dissertation Sharif University of Technology Esmaeili, Ashkan (Author) ; Marvasti, Farokh (Supervisor)
    Abstract
    In this dissertation, Data analysis and information retrieval from incomplete observations are investigated in different applications. Incomplete observations may be induced by lack of observations or part of data affected by specific noise (quantization noise). Data-driven algorithms are among important hot topics. Our goal is to process the lost information inducing certain assumption on big data structures. Then, the approach is to mathematically model the problem of interest as an optimization problem. Next, the designed algorithms for the optimization problems are proposed trying to cut down on the computational complexity of as well as enhancing recovery accuracy for big data... 

    Proposing a Resource Discovery Framework for Internet of Things Platforms

    , M.Sc. Thesis Sharif University of Technology Esmaeili, Mohsen (Author) ; Habibi, Jafar (Supervisor)
    Abstract
    The Internet of Things (IoT) is one of the fields witnessing a significant growth in recent years and is expected to make the lives of so many people go under substantial changes. IoT will exploit large numbers of smart objects in people’s everyday life to bring smartness into reality and this necessitates correct and seamless connection and integration between smart entities. One of the key tasks of the IoT platform is providing such a connection, which is assigned to the resource discovery framework.A resource discovery framework should consider requirements and challenges present in the IoT environment. Heeding the literature, one finds deficiencies in this field. These shortcomings are...