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    Development of Magnetic Iron Oxide Nanoparticles Encapsulated in the Polymeric Matrix and its Applications in the Study of Radionuclides Uptake

    , M.Sc. Thesis Sharif University of Technology Esmailnia, Sahar (Author) ; Otukesh, Mohammad (Supervisor) ; Khanchi, Alireza (Supervisor)
    Abstract
    Nanoparticles have attracted the attention of many researchers because of the distinct physical and chemical properties. Besides the traditional applications in plastic reinforcement, fluid rheological additive, etc., the nanoparticles could be applied to many new fields and high-functional devices. Various chemical methods have been employed for the production of nanoparticles with narrow size distribution, such as co-precipitation, micro-emulsion, electrochemical synthesis, hydrothermal synthesis, sol–gel processing, flame spray pyrolysis, plasma chemical vapor deposition (CVD), hot-soap method and electrospray pyrolysis. But most of them have some problems so that only a few of them... 

    Electrodeposition of Pt nanostructures and its Application as Glucose Sensor

    , Ph.D. Dissertation Sharif University of Technology Mahshid, Sahar Sadat (Author) ; Dolati, Abolghasem (Supervisor) ; Ghorbani, Mohammad (Supervisor)
    Abstract
    The present work describes sensing application of modified Pt nanostructures towards detection of glucose. Modified Pt nanostructured electrodes were prepared using electrodeposition method such as chronoampermetry and potentiostatic pulse methods. The electrodeposition of Pt nanostructures was first studied by voltammetry and amperommetry techniques and then potentiostatic pulse method has been used to produce the alloyed structures of platinum. In this regard, the first electrode was proposed based on alloyed Pt/Ni nanowire arrays (NWAs) for the non-enzymatic detection of glucose. The Pt/Ni NWAs were prepared by pulse electrodeposition of Pt and Ni within a nano-pore polycarbonate (PC)... 

    Quantum Estimation of Open Systems Using Extended Cramer-Rao Bounds

    , M.Sc. Thesis Sharif University of Technology Mehboudi, Mohammad (Author) ; Rezakhani, Ali (Supervisor) ; Alipour, Sahar (Co-Advisor)
    Abstract
    Any physical system is characterized with some set of quantities or parameters, knowing which, is equivalent to estimation of the system. Evaluating such parameters is usually done using tomography methods. An important question to ask, is how to increase the precision of measurement, being able to do some specific set of physical operations, say, measurement?
    this question is more important in parameter estimation in quantum meanical systems. It has been shown that, quantum meanics causes a fundamental limit, on precision of estimating su parameters, escribed by the so called “antum Cramér-Rao bound”.We must note that almost all quantum meanical systems are interacting with the... 

    Selective Transfection of Smart Polymeric Nanoparticles Into Reactive Astrocytes in Animal Model of Spinal Cord Injury

    , Ph.D. Dissertation Sharif University of Technology Sabourian, Parinaz (Author) ; Frounchi, Masoud (Supervisor) ; Mashayekhan, Shohreh (Co-Supervisor) ; Kiani, Sahar (Co-Supervisor)
    Abstract
    In this study, chitosan-based nanoparticles were prepared due to their biocompatibility, availability, high loading capacity of drug, stimulus responsive behavior and the presence of active functional groups. Chitosan was chemically functionalized with reactive oxygen species (ROS)-responsive moiety to respond to the oxidative stess and endosomal pH in nerve injuries. To prepare nanoparticles, functinalized chitosan ionically gelated with pH-responsive polyanions with ROS-scavenging properties such as polyacrylic acid and hyaluronic acid. Then, pH- and ROS-responsive nanoparticles were used for selective transfection into reactive astrocytes and axonal regeneration in spinal cord injuries....