Sharif Digital Repository

Based on the importance of DNA/RNA binding proteins in different cellular processes, finding binding sites of them play crucial role in many applications, like designing drug/vaccine, designing protein, and cancer control. Many studies target this issue and try to improve the prediction accuracy with three strategies: complex neural-network structures, various types of inputs, and ML methods to extract input features. But due to the growing volume of sequences, these methods face serious processing challenges. So, this paper presents KDeep, based on CNN-LSTM and the primary form of DNA/RNA sequences as input. As the key feature improving the prediction accuracy, we propose a new encoding... 

Speech synthesis and its applications have been very attractive recently. The main purpose of this technique is to produce a speech signal with natural characteristics of human speech like prosody and emotion. Among all existing methods for speech synthesis, statistical parametric speech synthesis methods are more promising because ofhigher flexibility in comparison to other methods. One of the applications of speech synthesis is speech to speech translation. In these systems, the generated voice in target language should have the same characteristics as the input voice in source language. The main purpose of this research is to review and evaluate the cross lingual speaker adaptation... 

Surface piercing propellers are particular type of supercavitating propellers that are commonly used for High-speed vessels. Most studies on this type of propellers has been investigating the hydrodynamic forces. But in recent years with increase in SPPs diameter used in vessels, structural analysis of this type of propellers is considered. For this purpose, studies on the stresses exerted on the propeller structures under load is done with the help of Hydro elastic methods. In this type of analysis, structura of propeller is intended to be flexible and Displacements under pressure checked and Tensions resulting from it are studied.
The present Thesis using ANSYS software to analyze a... 

The increasing demand for autonomous vehicles and reliable communication protocols and hardware interfaces, such as CAN bus and USB, underscores the necessity for stable clock sources that maintain a low temperature coefficient (TC) over wide temperature ranges. This demand is particularly emphasized in applications such as wearables, network sensors, downhole devices, WSNs, and IoT, where long-lasting battery life and frequency-stable clock sources over a broad temperature range (e.g. -20 °C to 100 °C) are crucial. Traditionally, variations in frequency caused by temperature have been mitigated by employing off-chip components like crystals or ceramic based oscillators, but this approach... 

Pricing plays an important and essential role in the profit and income of companies. The importance of pricing is not only related to its role in the company's profitability, but it also changes the customer's understanding and loyalty towards the company and can create the company's reputation or destroy it. Determining the right price will increase product sales and increase customer loyalty and create a competitive advantage for the company. One of the most important and influential variables in product pricing is the amount of demand. The main challenge of companies for product pricing is the uncertainty in their demand. In order to deal with this problem, data-driven pricing is used.... 

Utilization of RAP in HMA reduces the initial costs, conserves natural sources and avoids disposal problems. Aged binder from RAP will have some effects on resultant binder. To date, solvent extraction and recovery is the only method that physically separates the RAP binder from the RAP aggregate for characterization. Time consuming for recovery, altering the physical properties of the recovered asphalt binder like binder hardening and the possibility that Asphalt binder is not completely extracted from the aggregate are the weak points of this method. Addressing the need for non-solvent based RAP binder characterization; procedures for low temperature characterization of RAP binder... 

Increased environmental concerns and high oil prices have encouraged highway agencies to maximize the use of recycled materials like Reclaimed Asphalt Pavements (RAP) in pavement construction. However, utilization of RAP has limited to low percentage, generally less than 25%. This is due aged, stiffer, and less strain tolerant asphalt binder in RAP. As the RAP proportion increases, a large amount of the aged binder will be introduced into the mixture. The excessive stiffness of HMA mixture tends to lead to less workable mixture. Studies were conducted to examine the effect of Sasobit on the workablility of high RAP mixtures. The results indicated while the utilization of Sasobit had improved... 

Asphalt concrete exhibits viscoelastic and viscoplastic behavior which is dependent on rate and temperature. To model this behavior, various mechanical modelshave been presented in which total strain, as the response of the applied stress, is decomposed by various researchers to recoverable and permanent strains.Accumulation and expansion of permanent response result in rutting which is a dominant and prevalent distress in hot mixed asphalt (HMA) in hot climates. The available models are not capable of accurately calculate the viscoplastic strain under cyclic loading.
To close this gap, recovered viscoelastic strain at rest (unloading) period was introduced. This parameter accounted for... 

Composite nature of asphalt mixtures necessitates a micromechanical scheme which depends on distinctive characteristics of various constitutive phases. In this regard, discrete element method was utilized to predict the creep behavior of asphalt mixtures and strain response in primary, secondary and tertiary stages. In this research, a modified mixture modeling procedure was considered to better simulate permanent deformation response of asphalt mixtures under creep loading. A random distribution of mastic and aggregate particles with respect to a typical dense gradation was implemented to reconstruct cylindrical specimens. A bonding model represented the cohesion effect in mastic...