Sharif Digital Repository

Based on the importance of DNA/RNA binding proteins in different cellular processes, finding binding sites of them play crucial role in many applications, like designing drug/vaccine, designing protein, and cancer control. Many studies target this issue and try to improve the prediction accuracy with three strategies: complex neural-network structures, various types of inputs, and ML methods to extract input features. But due to the growing volume of sequences, these methods face serious processing challenges. So, this paper presents KDeep, based on CNN-LSTM and the primary form of DNA/RNA sequences as input. As the key feature improving the prediction accuracy, we propose a new encoding... 

Speech synthesis and its applications have been very attractive recently. The main purpose of this technique is to produce a speech signal with natural characteristics of human speech like prosody and emotion. Among all existing methods for speech synthesis, statistical parametric speech synthesis methods are more promising because ofhigher flexibility in comparison to other methods. One of the applications of speech synthesis is speech to speech translation. In these systems, the generated voice in target language should have the same characteristics as the input voice in source language. The main purpose of this research is to review and evaluate the cross lingual speaker adaptation... 

Surface piercing propellers are particular type of supercavitating propellers that are commonly used for High-speed vessels. Most studies on this type of propellers has been investigating the hydrodynamic forces. But in recent years with increase in SPPs diameter used in vessels, structural analysis of this type of propellers is considered. For this purpose, studies on the stresses exerted on the propeller structures under load is done with the help of Hydro elastic methods. In this type of analysis, structura of propeller is intended to be flexible and Displacements under pressure checked and Tensions resulting from it are studied.
The present Thesis using ANSYS software to analyze a... 

The increasing demand for autonomous vehicles and reliable communication protocols and hardware interfaces, such as CAN bus and USB, underscores the necessity for stable clock sources that maintain a low temperature coefficient (TC) over wide temperature ranges. This demand is particularly emphasized in applications such as wearables, network sensors, downhole devices, WSNs, and IoT, where long-lasting battery life and frequency-stable clock sources over a broad temperature range (e.g. -20 °C to 100 °C) are crucial. Traditionally, variations in frequency caused by temperature have been mitigated by employing off-chip components like crystals or ceramic based oscillators, but this approach... 

Pricing plays an important and essential role in the profit and income of companies. The importance of pricing is not only related to its role in the company's profitability, but it also changes the customer's understanding and loyalty towards the company and can create the company's reputation or destroy it. Determining the right price will increase product sales and increase customer loyalty and create a competitive advantage for the company. One of the most important and influential variables in product pricing is the amount of demand. The main challenge of companies for product pricing is the uncertainty in their demand. In order to deal with this problem, data-driven pricing is used.... 

In the current situation and considering the economic conditions, entrepreneurship and self-employment are important factors of business growth. To prepare people in this field, there is a need for effective training that can motivate people. Identifying the effective methods and different dimensions of the entrepreneurship education framework that can lead to setting up a successful program for training people and facilitate the way to achieve the goal of education is one of the important goals of this research. By studying the literature from 2010 onwards, this research systematically examined 96 articles and tried to improve the framework of entrepreneurship education that was stated in... 

Considering the widespread applications of amides, synthesis of these compounds is of great importance. The one pot oxidative addition of amines to aldehydes is one of the most simple and appealing approaches to synthesis amides. With the aim of developing a mild and convenient approach towards preparation of amides, numerous methods have been reported for this important process over the past few decades. These improvements have been mostly related to the optimization of reaction conditions and the use of more challenging substrates including diverse derivatives of aldehydes, and also design a novel and effective catalytic systems. Due to the various advantages of supported heterogeneous... 

Research on the characteristics of the near field earthquakes has been very popular in recent years due to the considerable damages they have caused to the structures located within the vicinity of seismic sources. The incapability of response spectra for structural damage assessment has been revealed through recent investigations. The recorded data show that the near field earthquakes are often accompanied by a large energy pulse in the beginning of the records caused by the so-called directivity phenomenon. That has encouraged many researchers to study the possibility of using the velocity pulse of these records to evaluate the imposed seismic demands on structures. Thus, investigating the... 

Due to the environmental concern for the harmful effect of the release of HFCs on global warming there has been more interest for the use of hydrocarbons as refrigerants in recent years. In this project the performance of these refrigerants have been studied and compared with common refrigerants from the quantitative and qualitative point of view using a real-scale model of Peugeot-405 air conditioning system. Charging amount, inside temperature, cooling load, energy consumption of cycle, coefficient of performance and required time to steady state condition are the important comparative criteria for such a study. After carrying out a series of tests it has been considered that charge... 

Metabonomics is a quantitative measurement of time dependent metabolic interactions for living systems in response to the pathological or genetic variations. NMR spectroscopy has emerged as a key tool for understanding metabolic processes in living systems. In this project, the study of metabolomics was performed as classification and regression on samples of parkinson’s disease, multiple sclerosis disease, celiac disease and crohn’s disease. In classification part, various methods were applied using optimal parameters.classification methods in Parkinson’s disease, multiple sclerosis disease, celiac disease and crohn’s disease were RF, CART, PLS-DA, RF and RF respectively. Based on the... 

Prediction of groundwater level fluctuations is absolutely necessary for the proper manag ement of these precious resources. There are different methods to predict hydrological time series such as groundwater level. Linear models inefficiency in predicting nonlinear and n on-stationary time series cause researchers widely use artificial intelligence techniques such as Artificial Neural Networks (ANN), Fuzzy Inference System (FIS), Genetic Algorithm (GA) and their hybrid models such as Artificial Neural – Fuzzy Inference System (ANFIS). These smart models are capable to simulate nonlinear and non-stationary time series in suitable accu-racy using by a few time and data. By emersion of Wavelet... 

Foundation is the lowest load-bearing part of a structure and a part of underneath soil that is affected by the structure load. In fact, foundation transfers the loads from the superstructure to the substructure, preventing excessive settlement of soil or stresses exceeding soil bearing capacity. Indeed, almost all structures are placed on the ground, therefore the effects of soil and structure on each other, which is known as Soil Structure Interaction (SSI), is considered as a key factor in many important and engineered structures. In contrast to structures on a rigid footing, a flexible foundation may show stiffness degradation along with an increase of damping and natural period of the... 

In this project three models addressed before in the references are reviewed and the stability margins of radome error slope obtained by analytical method. Then a new model who is usefull in practical applications presented. Because of complication of this model the model is simplified and stability margins for radome error slope derived in simplified model. It is also shown that simplified applicative model is similar to model purposed in ref. [6]. Then a PD controller designed to stabilize some of models reviewed in chapter 3. The equations derived before verified in continuation of the project. The effects of parameters on the stability of missile analysed by equations derived in chapter... 

In this research the problem is the development and simulation of Transfer Alignment algorithm for an aerial launch space launch vehicle. In the references there is no complete study on development of this algorithm for the case space launch vehicle. In order to develop the algorithm, the carrying airplane and the space launch navigation systems are considered as the Master INS and Slave INS respectively. First a 6DOF simulation of the airplane is presented. Then the desired inputs for simulation of Master and Slave INS are generated. Also the differences of the inputs of Slave INS caused by the distance between the Master and Slave INS is considered. Master INS performs as an ideal INS and... 

One of the most important issues among defense is the increasing of the defense power using present facilities. Therefore, optimal setting and arrangement of equipment by considering different air-to-earth attack of enemy without knowing of properties and capabilities of available systems may not be possible. So, using defense equipment considering properties of them, and paying attention to existence restrictions and effective elements can have an effective role with the design of suitable algorithm.The main purposes of this thesis are: maximization of the efficiency of a defense system against. aerial invader targets, achieving the best arrangement of defense equipment based on suggested...