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    Design and Analysis of Hot Gas Diffuser for High Altitude Simulation

    , M.Sc. Thesis Sharif University of Technology Mirbabaei, Ahmad Reza (Author) ; Farahani, Mohammad (Supervisor) ; Fooladi, Nematollah (Co-Advisor)
    Abstract
    In order to test the performance of engines used at high altitudes, a vacuum simulator system is used. In the vacuum test stand the supersonic exhaust diffuser is used to create the vacuum conditions and the automatic discharge of combustion gases into the atmosphere. usually, the exhaust gas temperature of the engine nozzle is much higher than the temperature that steel body of diffuser can stand (above 2500 K). The purpose of this study is to design and analyze a cooling system to protect the diffusers body. In this study, first by comparing different cooling methods, a spray-cooled water treatment method has been selected for the problem. A new algorithm for designing a spray cooling... 

    Development of Carbon Management Hierarchy Method Based on Process Integration Techniques

    , M.Sc. Thesis Sharif University of Technology Fooladi, Fatemeh (Author) ; Avami, Akram (Supervisor)
    Abstract
    Continuous increase of energy demand, scarcity of resources, as well as environmental limitations have led to the need to reduce carbon emissions. In this research, an MINLP model based on the mathematical optimization formulation is proposed to reach this issue in a large cogeneration unit. Advantage of the hierarchical approach for carbon management are avoiding individual carbon reduction policies, and embedding emission control techniques in a hierarchical mathematical model that helps us to select the most appropriate policies and prioritize each other. In the carbon management hierarchy, the optimization of the base cycle is done at the first stage. Then, the use of renewable energies... 

    Techno-Economic Comparison between Reverse Osmosis and Multi-Effect Distillation for Desalination in Iran

    , M.Sc. Thesis Sharif University of Technology Fooladi, Hassan (Author) ; Bastani, Dariush (Supervisor) ; Feylizadeh, Mehrzad (Supervisor)
    Abstract
    The current work studies the economic investigation of reverse osmosis (RO) desalination unit and multi-effect distillation (MED) considering the average global and also Iran circumstances. Technical and operational parameters are taken into account for economic modeling of both methods to choose the proper and economic method for water desalination based on different operational conditions. The cost of the desalination plants is investigated in two different parts of capital cost and operating and maintenance cost. Capital cost is divided into direct and indirect cost subsections. Based on these calcifications, the effect of economic parameters on change of capital cost and operating and... 

    A novel sensitive aptamer-based nanosensor using rGQDs and MWCNTs for rapid detection of diazinon pesticide

    , Article Journal of Environmental Chemical Engineering ; Volume 9, Issue 1 , 2021 ; 22133437 (ISSN) Fooladi Talari, F ; Bozorg, A ; Faridbod, F ; Vossoughi, M ; Sharif University of Technology
    Elsevier Ltd  2021
    Abstract
    An optical apta-nanosensor was designed and developed based on reduced graphene quantum dots (rGQDs) and multi-walled carbon nanotubes (MWCNTs) and applied for the selective detection of diazinon as one of the most widely used organophosphorus pesticides. Considering the GQDs and rGQDs high fluorescence emission and optical stability, efficient optical transducers could be designed and precise detection methods could be developed based on such transducers. Herein, by using rGQDs, diazinon specific aptamer, and MWCNTs, a simple economical fluorescence method has been introduced to detect and measure diazinon with the detection limit of 0.4 nM (0.1 μg/L) in the range of 4-31 nM, meeting the... 

    A fast and accurate multi-cycle soft error rate estimation approach to resilient embedded systems design

    , Article Proceedings of the International Conference on Dependable Systems and Networks, 28 June 2010 through 1 July 2010 ; June , 2010 , Pages 131-140 ; 9781424475018 (ISBN) Fazeli, M ; Miremadi, S. G ; Asadi, H ; Nematollah Ahmadian, S ; Sharif University of Technology
    2010
    Abstract
    In this paper, we propose a very fast and accurate analytical approach to estimate the overall SER and to identify the most vulnerable gates,flip-flops, and paths of a circuit. Using such information, designers can selectively protect the vulnerable parts resulting in lower power and area overheads that are the most important factors in embedded systems. Unlike previous approaches, the proposed approach firstly does not rely on fault injection or fault simulation; secondly it measures the SER for multi cycles of circuit operation; thirdly, the proposed approach accurately computes all three masking factors, namely, logical, electrical, and timing masking; fourthly, the effects of error... 

    Experimental Investigation of Pressure Oscillations Phenomenon in Test Chamber of High-Altitude Simulator

    , M.Sc. Thesis Sharif University of Technology Nojoumi, Amir Ali (Author) ; Farahani, Mohammad (Supervisor) ; Fouladi, Nematollah (Supervisor)
    Abstract
    Depending on the geometry and nozzle pressure, increasing the ratio of the diffuser inlet area to the nozzle outlet area can lead to instability in the high-altitude simulator vacuum chamber startup process. This instability results in the formation of harmonic pressure oscillations throughout the diffuser and the vacuum chamber. In this study, a scaled down second throat diffuser with compressed air has been utilized. The performance of the diffuser has been investigated using four conical nozzles with different expansion ratios to simulate instability at area ratios of 1.27, 1.91, 4.1, and 7.81 with rapid nozzle pressure rise. Experiments were conducted by measuring wall pressures along... 

    Enhanced Waddington landscape model with cell-cell communication can explain molecular mechanisms of self-organization

    , Article Bioinformatics ; Volume 35, Issue 20 , 2019 , Pages 4081-4088 ; 13674803 (ISSN) Fooladi, H ; Moradi, P ; Sharifi Zarchi, A ; Hosein Khalaj, B ; Berger, B ; Sharif University of Technology
    Oxford University Press  2019
    Abstract
    The molecular mechanisms of self-organization that orchestrate embryonic cells to create astonishing patterns have been among major questions of developmental biology. It is recently shown that embryonic stem cells (ESCs), when cultured in particular micropatterns, can self-organize and mimic the early steps of pre-implantation embryogenesis. A systems-biology model to address this observation from a dynamical systems perspective is essential and can enhance understanding of the phenomenon. Results: Here, we propose a multicellular mathematical model for pattern formation during in vitro gastrulation of human ESCs. This model enhances the basic principles of Waddington epigenetic landscape... 

    Development of Compact Finite Difference Boltzmann Method for Simulating Compressible Rarefied Gas Flow

    , M.Sc. Thesis Sharif University of Technology Alemi Arani, Ali (Author) ; Hejranfar, Kazem (Supervisor) ; Fouladi, Nematollah (Co-Supervisor)
    Abstract
    In this work, a high-order accurate gas kinetic scheme based on the compact finite-difference Boltzmann method (CFDBM) is developed and applied for simulating the compressible rarefied gas flows. Here, the Shakhov model of the Boltzmann equation is considered and the spatial derivative term in the resulting equation is discretized by using the fourth-order compact finite-difference method and the time integration is performed by using the third-order TVD Runge-Kutta method. A filtering procedure with three discontinuity-detecting sensors is applied and examined for the stabilization of the solution method especially for the problems involving the discontinuity regions such as the shock. The... 

    Design and Analysis of an Optimal Cooling System for a Supersonic Exhaust Diffuser Using a Water Jacket

    , M.Sc. Thesis Sharif University of Technology Mahdian Dowlatabadi, Milad (Author) ; Farahani, Mohammad (Supervisor) ; Fouladi, Nematollah (Supervisor)
    Abstract
    Often in a vacuum test facility, a supersonic exhaust diffuser uses the energy of the outflow from the nozzle to create and maintain a vacuum condition in the engine test chamber. In this system, the temperature of the motor exhaust gas, which directly hits the diffuser walls, is much higher than the tolerance of the metal body of the diffuser. The purpose of this research is to design a cooling system for thermal protection of diffuser walls of a vacuum simulator using a water-jacket tool. At the beginning of this study, the effective parameters in the design of the water-jacket cooling system were identified. Then, a new algorithm to design and optimize the water-jacket cooling system was... 

    Investigation of the Starting Process of a Second Throat Exhaust Diffuser in a High-Altitude Test Stand

    , M.Sc. Thesis Sharif University of Technology Parsa Delivand, Ahmad Reza (Author) ; Farahani, Mohammad (Supervisor) ; Fouladi, Nematollah (Supervisor)
    Abstract
    In the present study, the effect of the diffuser inlet-to-nozzle exit area ratio (A_d/A_e ) on the gradual starting performance of a second throat exhaust diffuser has been investigated experimentally. Experiments have been carried out with four conical nozzles with different expansion ratios and considering two approaches of gradual increase and gradual decrease of nozzle chamber pressure by a high-pressure air tank. Investigations show that at high area ratios before starting the diffuser, oscillations in the pressure of the test chamber are created due to the instability of the flow at the diffuser inlet. By frequency analysis of the vacuum chamber pressure, it is observed that as A_d/A_e... 

    Cell Separation via Nano-porous Molecularly Imprinted Polymer

    , M.Sc. Thesis Sharif University of Technology Rahnema Falavarjani, Eiman (Author) ; Abdekhodaie, Mohammad Jafar (Supervisor) ; Nematollah Zade, Ali (Co-Advisor)
    Abstract
    Molecularly imprinted polymers (MIPs) with synthetic recognition sites are capable of detecting and separating chemical species in complex environments. These characteristics are of increasing interest for bioanalytical applications. The chief advantages of MIPs are mechanical and chemical stability, low cost, and ease of preparation. Recently, imprinting technology has been used for fabrication polymer thin films with recognition sites of proteins, plant viruses, and yeasts. Also few investigations applied lithography for synthesis of cell imprinted polymers targeting cell detection and observation of cell morphology.
    For the first time, we demonstrate surface imprinting for the... 

    Development of Polymerization Method to Produce Spherical Polymer Particles with Nanoscale Porosity in Packed Beds

    , M.Sc. Thesis Sharif University of Technology Karimi, Mehdi (Author) ; Shojaei, Akbar (Supervisor) ; Abd Khodaei, Mohammad Jafar (Supervisor) ; Nematollah Zadeh, Ali (Co-Advisor)
    Abstract
    Porous polymeric particles have the extensive application in various sciences and various methods have been introduced for production of these particles. Depending on method of production, porous polymeric beads can be produced in diverse shapes, pore size, pores interconectivity, surface morphology and chemical properties. In common methods for production of porous polymeric particles, tuning the size and porosity is difficult or even impossible. Porous polymeric beads with the vast surface area and good functionality have been applied for adsorption of various materials. The purpose of this study is therefore to investigate a new procedure for the production of porous polymeric...