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    Enhancement Of the Quality In PET Brain Images Using AutoGANcoder Algorithms

    , M.Sc. Thesis Sharif University of Technology Razavi Satvati, Reyhaneh Sadat (Author) ; vosoughi, Naser (Supervisor) ; Ghafarian, Pardis (Co-Supervisor) ; Attari, Ali Akbar (Co-Supervisor)
    Abstract
    Positron Emission Tomography (PET) is a cutting-edge medical imaging technique that enables the examination of functional activities in different regions of the body, particularly the brain. This technique involves injecting a radiopharmaceutical into the body, which emits gamma rays that are subsequently detected by the PET scanner to generate images. However, a significant challenge in PET imaging is the degradation of image quality due to noise and photon scattering, which can lead to diagnostic errors, especially in sensitive applications such as detecting brain diseases. Various image reconstruction techniques have been developed in the past to mitigate attenuation and scattering... 

    Investigation of the compression in Equal Channel Angular Extrusion with Forward Extrusion

    , M.Sc. Thesis Sharif University of Technology Ghafarian Malmiri, Hadi (Author) ; Karimi Taheri, Ali (Supervisor)
    Abstract
    In recent years, more attention was devoted to ECAE process than any other Severe Plastic Deformation (SPD) process. Repeatability of the process and high mechanical properties of the exit profile are the reasons of this attention. ECAE process carried out with conventional extrusion process, provides more strain and back pressure. In this thesis an analytical model based on upper Bound analysis and Bezier interpolation functions is presented and the effects of process parameters were studied. According to the presented model, reduction of inner corner angle φ, increases strain, strain rate and press force. Reduction of the outer corner angle ψ, causes the same effect. Moreover, decreasing... 

    Scattering Correction in PET Device using Deep Learning

    , M.Sc. Thesis Sharif University of Technology Kamalizadeh, Zeynab (Author) ; Vosoghi, Naser (Supervisor) ; Ghaffarian, Pardis (Co-Supervisor) ; Sheikhzadeh, Peyman (Co-Supervisor)
    Abstract
    Positron Emission Tomography (PET) imaging is a modern sectional imaging technique widely used due to its advantages in visualizing the physiological functions of body tissues. In this method, a radiotracer is injected into the body, concentrating in the area of interest. As the positron-emitting radionuclide decays, positron annihilation occurs, resulting in the emission of two gamma rays in opposite directions. The PET scanner detects these gamma rays; however, scattering may occur during their journey from the patient’s body to the detector, which can introduce errors in tumor localization. To reconstruct images and correct for these scatter effects, various techniques such as iterative... 

    A four-phase algorithm to improve reliability in series-parallel systems with redundancy allocation

    , Article Scientia Iranica ; Vol. 21, issue. 3 , 2014 , p. 1072-1082 Ghafarian Salehi Nezhad, A ; Eshraghniaye Jahromi A ; Salmani, M. H ; Ghasemi, F ; Sharif University of Technology
    2014
    Abstract
    In general, reliability is the ability of a system to perform and maintain its functions in routine, as well as hostile or unexpected, circumstances. The Redundancy Allocation Problem (RAP) is a combinatorial problem which maximizes system reliability by discrete simultaneous selection from available components. The main purpose of this study is to develop an effective approach to solve RAP, expeditiously. In this study, the basic assumption is considering Erlang distribution density for component failure rates. Another assumption is that each subsystem can have one of cold-standby or active redundancy strategies. The RAP is a NP-Hard problem which cannot be solved in reasonable time using... 

    Implementation of absolute quantification in small-animal SPECT imaging: Phantom and animal studies

    , Article Journal of Applied Clinical Medical Physics ; Volume 18, Issue 4 , 2017 , Pages 215-223 ; 15269914 (ISSN) Gerdekoohi, S. K ; Vosoughi, N ; Tanha, K ; Assadi, M ; Ghafarian, P ; Rahmim, A ; Ay, M. R
    John Wiley and Sons Ltd  2017
    Abstract
    Purpose: Presence of photon attenuation severely challenges quantitative accuracy in single-photon emission computed tomography (SPECT) imaging. Subsequently, various attenuation correction methods have been developed to compensate for this degradation. The present study aims to implement an attenuation correction method and then to evaluate quantification accuracy of attenuation correction in small-animal SPECT imaging. Methods: Images were reconstructed using an iterative reconstruction method based on the maximum-likelihood expectation maximization (MLEM) algorithm including resolution recovery. This was implemented in our designed dedicated small-animal SPECT (HiReSPECT) system. For... 

    A novel method for measuring the MTF of CT scanners: A phantom study

    , Article 2019 IEEE International Symposium on Medical Measurements and Applications, MeMeA 2019, 26 June 2019 through 28 June 2019 ; 2019 ; 9781538684276 (ISBN) Khodajou Chokami, H ; Hosseini, S. A ; Reza Ay, M ; Safarzadehamiri, A ; Ghafarian, P ; Zaidi, H ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2019
    Abstract
    The modulation transfer function (MTF) is well known as a crucial parameter in quality assurance of computed tomography (CT) scanners, which provides detailed information of both contrast and resolution of CT images. Different methods have been introduced and developed to calculate the MTF of CT scanners. However, a robust methodology which accurately estimates the MTF of CT scanners under the use of every range of object electron density and tube current-time product (mAs) has not been reported so far. To this aim, a new wavelet-based circular edge method for MTF measurement has been presented in this work. Owning to the edge spread function (ESF) susceptibility to noise, the approach was...