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ghazagh--parisa
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HAP/Agar Nanocarriers for Bone Anti-infection Drug
, M.Sc. Thesis Sharif University of Technology ; Frounchi, Masood (Supervisor)
Abstract
Successful treatment of bone infections is a major orthopedic challenge due to the physiological and anatomical features of bone. In this project, we prepared a drug delivery system with injectable and biodegradable polysaccharide agar containing alginate, polyvinyl alcohol and hydroxyapatite nanocarriers composite microspheres. Alginate and polyvinyl alcohol composite microspheres are crosslinked by calcium and freeze-thawing technique. Using the freeze thawing process for polyvinyl alcohol crosslinking, in addition to alginate crosslinking, improved hydrogel swelling behavior and enhanced drug loading and thus slowed drug release, drug loading increased with increasing PVA percentage from ...
Experimental Study of Drying and Calcination of Simulated High-Level Waste (HLW)
, M.Sc. Thesis Sharif University of Technology ; Samadfam, Mohammad (Supervisor) ; Zahakifar, Fazel (Supervisor) ; Zaheri, Parisa (Co-Supervisor)
Abstract
One of the novel methods of stabilization of nuclear waste is the use of vitrification technology. In order to stabilize high level wastes (HLLW) in glass, it is required that the elements are in their oxide form. Therefore, it is necessary to evaporate the waste and turn it into a solid form so that the elements can be converted into oxide form in the calcination furnace. Hence, one of the challenges of stabilization is the optimization of evaporation and calcination conditions. In this research, the parameters affecting evaporation were first investigated. Using laboratory measurements of application: temperature (110 to 180 °C), presence of nitric acid (0.5 to 4 mol/L), ratio of zirconium...
Fabrication Patient-Specific Drill Guide Templates for Cervical Pedicle Screw Placement
, M.Sc. Thesis Sharif University of Technology ; Arjmand, Navid (Supervisor) ; Parnianpour, Mohammad (Supervisor) ; Azimi, Parisa (Co-Supervisor)
Abstract
One of the most common spinal surgeries involves spinal fusion or vertebral fixation, which is used to treat various conditions such as intervertebral disc disease, scoliosis (lateral deviation of the spinal column), fractures, infections, or the presence of tumors in the spinal column. In this surgical procedure, the use of pedicle screws and titanium rods prevents motion and friction between two vertebrae. Screws may enter the vertebrae in the wrong position and angle, causing bone weakening, rupture of nerve roots or blood vessels, weakness or lack of sensation in some parts of the body, spinal cord injury, and in severe cases, paralysis of the patient. For this reason, fusion surgery is...