Sharif Digital Repository

Application of the advanced control techniques and information technology in the biomedical engineering have been the focal point of the research communities in biomedical engineering due to the rapid growth of the nonlinear control theories along with the computer hardware. In this work the application of differential geometry and globally linearizing control has been applied to efficiently control the first phase of HIV disease based on the HIV infection model proposed in the literature. All the efforts have been in the way to obtain a suitable scenario of drug administration to suppress and control the infection. In the proposed scenario, drug administration is time dependant and... 

Variation in value and initial cost of construction contracts in many cases lead to considerably increasing the finalized price. These increases are sometimes so big enough that the 25 percent of limitation which could be added to contracts couldn't make them to be finalized and exploitable, so the necessity of a new contract sometimes up to 100 percent or even up to 200 percent of initial cost for completing the same project is inevitable. Although in some specific and rare cases we couldn't avoidance from these changes, but observing the growth of these changes in public construction projects of Iran increase the requirement of special attention in order to find the main causes, prevention... 

Based on the importance of DNA/RNA binding proteins in different cellular processes, finding binding sites of them play crucial role in many applications, like designing drug/vaccine, designing protein, and cancer control. Many studies target this issue and try to improve the prediction accuracy with three strategies: complex neural-network structures, various types of inputs, and ML methods to extract input features. But due to the growing volume of sequences, these methods face serious processing challenges. So, this paper presents KDeep, based on CNN-LSTM and the primary form of DNA/RNA sequences as input. As the key feature improving the prediction accuracy, we propose a new encoding... 

Speech synthesis and its applications have been very attractive recently. The main purpose of this technique is to produce a speech signal with natural characteristics of human speech like prosody and emotion. Among all existing methods for speech synthesis, statistical parametric speech synthesis methods are more promising because ofhigher flexibility in comparison to other methods. One of the applications of speech synthesis is speech to speech translation. In these systems, the generated voice in target language should have the same characteristics as the input voice in source language. The main purpose of this research is to review and evaluate the cross lingual speaker adaptation... 

Surface piercing propellers are particular type of supercavitating propellers that are commonly used for High-speed vessels. Most studies on this type of propellers has been investigating the hydrodynamic forces. But in recent years with increase in SPPs diameter used in vessels, structural analysis of this type of propellers is considered. For this purpose, studies on the stresses exerted on the propeller structures under load is done with the help of Hydro elastic methods. In this type of analysis, structura of propeller is intended to be flexible and Displacements under pressure checked and Tensions resulting from it are studied.
The present Thesis using ANSYS software to analyze a... 

Pricing plays an important and essential role in the profit and income of companies. The importance of pricing is not only related to its role in the company's profitability, but it also changes the customer's understanding and loyalty towards the company and can create the company's reputation or destroy it. Determining the right price will increase product sales and increase customer loyalty and create a competitive advantage for the company. One of the most important and influential variables in product pricing is the amount of demand. The main challenge of companies for product pricing is the uncertainty in their demand. In order to deal with this problem, data-driven pricing is used.... 

The increasing demand for autonomous vehicles and reliable communication protocols and hardware interfaces, such as CAN bus and USB, underscores the necessity for stable clock sources that maintain a low temperature coefficient (TC) over wide temperature ranges. This demand is particularly emphasized in applications such as wearables, network sensors, downhole devices, WSNs, and IoT, where long-lasting battery life and frequency-stable clock sources over a broad temperature range (e.g. -20 °C to 100 °C) are crucial. Traditionally, variations in frequency caused by temperature have been mitigated by employing off-chip components like crystals or ceramic based oscillators, but this approach... 

A large number of bridges in Iran are deteriorating under long and heavy traffic loadings, while getting closer to the end of their design life time. Therefore, many of them have been exhibiting various problems such as excessive vibration or large deflection under the normal service loadings. So, mitigating traffic-induced bridge vibration and damages is necessary to extend their efficient period of serviceability. On the other hand, application of active and passive control devices in structural retrofitting have absorbed the attention of many engineers and researchers. In this work, the performance of an active control system made of piezoelectric actuators is investigated in reducing the... 

The main goal of the current building design codes is to protect life safety, and generally, they do not directly address other societal, economic, etc., concerns regarding earthquakes. However, recent earthquakes around the world have shown that the effects of earthquakes' damages and losses can go beyond life-safety concerns. This observation has led many renowned scholars, organizations, and agencies to state the need to change the current design codes. In this regard, this thesis investigates the basis of setting the seismic design requirements and suggests a method in this respect. The study consists of two main parts. Part I (theory and design methodology) discusses some theoretical... 

Autonomous vehicles, as an integral part of intelligent transportation systems, will play a significant role in the future of transportation services. These vehicles have a high potential to improve road traffic capacity and the efficiency of transportation systems. One type of autonomous vehicle is the connected and autonomous vehicle (CAV), which can communicate with each other, roadside units, traffic control signals, and other infrastructures or devices. This study investigates the impact of autonomous vehicles and connected and autonomous vehicles on the traffic flow of the Tehran-Karaj freeway and vice versa, under various penetration rates and in a mixed traffic environment. In this... 

In the current situation and considering the economic conditions, entrepreneurship and self-employment are important factors of business growth. To prepare people in this field, there is a need for effective training that can motivate people. Identifying the effective methods and different dimensions of the entrepreneurship education framework that can lead to setting up a successful program for training people and facilitate the way to achieve the goal of education is one of the important goals of this research. By studying the literature from 2010 onwards, this research systematically examined 96 articles and tried to improve the framework of entrepreneurship education that was stated in...