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    Dosign and Construction of Natural Polymers-based Hydrogels for Cartilage Tissue Engineering

    , M.Sc. Thesis Sharif University of Technology Nasiri, Bita (Author) ; Mashayekhan, Shohreh (Supervisor) ; Hajebrahimi, Zahra (Supervisor)
    Abstract
    Once damaged, articular cartilage has very little capacity for spontaneous healing because of the avascular nature of the tissue. Although many repair techniques have been proposed over the past decades, none has successfully regenerated long-lasting tissue to replace damaged cartilage. Tissue engineering have recently demonstrated tremendous approaches for regeneration of cartilage tissue lesions. Tissue engineering is based on three principles: cells, scaffolds for cell adhesion and growth factors. Three-dimensional biodegradable scaffolds play an important role in tissue engineering. In this study, novel cross-linked hybrid chitosan/ECM scaffolds were prepared for articular cartilage... 

    Design of Impedance Surfaces with Metamaterials and Metasurfaces to Implement Line Wave

    , M.Sc. Thesis Sharif University of Technology Hajebrahimi, Marzieh (Author) ; Khavasi, Amin (Supervisor)
    Abstract
    In this thesis we introduce line wave. Which propagates only in one direction and dissipate in other direction. Line wave can propagates at the interface of two complementary impedance surfaces. There are various ways to build a waveguide which can support line waves like complementary structures. In this thesis we try to find a way which will not use complementary structures. Hence we use Spoof Surface Plasmon Polariton concept to mimic complementary structure characteristics. A complementary surface-based waveguide consists of two parts; one part supports TE polarization waves and the other one supports TM polarization waves. When these TE and TM waves face each other in the boundary, line... 

    Construction of scaffolds composed of acellular cardiac extracellular matrix for myocardial tissue engineering

    , Article Biologicals ; Volume 53 , 2018 , Pages 10-18 ; 10451056 (ISSN) Esmaeili Pourfarhangi, K ; Mashayekhan, S ; Ghanbari Asl, S ; Hajebrahimi, Z ; Sharif University of Technology
    Academic Press  2018
    Abstract
    High rates of mortality and morbidity stemming from cardiovascular diseases unveil extreme limitations in current therapies despite enormous advances in medical and pharmaceutical sciences. Following myocardial infarction (MI), parts of myocardium undergo irreversible remodeling and is substituted by a scar tissue which eventually leads to heart failure (HF). To address this issue, cardiac patches have been utilized to initiate myocardial regeneration. In this study, a porous cardiac patch is fabricated using a mixture of decellularized myocardium extracellular matrix (ECM) and chitosan (CS). Results of rheological measurements, SEM, biodegradation test, and MTT assay showed that the... 

    Mesoporous silica nanoparticles (MCM-41) coated PEGylated chitosan as a pH-Responsive nanocarrier for triggered release of erythromycin [electronic resource]

    , Article International Journal of Polymeric Materials and Polymeric Biomaterials ; 2014, Volume 63, Issue 13, Pages 692-697 Pourjavadi, A. (Ali) ; Mazaheri Tehrani, Zahra ; Sharif University of Technology
    Abstract
    A pH-responsive drug delivery system based on core shell structure of mesoporous silica nanoparticle (MSN) and chitosan-PEG copolymer was prepared and characterized by Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), scanning electron microscope (SEM), and high-resolution transmission microscope (HR-TEM) techniques. In order to improve compatibility MSN and drug, mesoporous nanosilica was modified by 3-aminopropyl triethoxysilane. The release of erythromycin (a macrolide antibiotic) as a model drug was investigated in two pHs, 7.4 and 5.5  

    Using Nonlinear Effects of Light for Optical Signal Processing

    , M.Sc. Thesis Sharif University of Technology Shatery, Farshid (Author) ; Kavehvash, Zahra (Supervisor)
    Abstract
    Ultrafast signal processing in time-domain with high resolution and reconfigura-bility is a challenging task. This paper, for the first time, introduces a time-varying metasurface consisting of graphene microribbon array for implementing time-lens in the terahertz domain. Given that the surface conductivity of graphene is proportional to the Fermi energy level in the THz regime, it is possible to change the phase property of the incident electromagnetic pulse by changing the Fermi level while the Fermi level itself is a function of voltage. Upon this fact, a quadratic temporal phase modulator, namely time-lens has been realized. This phase modulation is applied to the impinging signal in the... 

    Theoretical and Computational Investigation of Quantum Plasmonic Properties of Nanocluster Dimers

    , M.Sc. Thesis Sharif University of Technology Mahmoudi, Erfan (Author) ; Jamshidi, Zahra (Supervisor)
    Abstract
    In today's era, metal nanoparticles play an important role in technologies emerging from different sciences, such as chemistry, physics, optics, material science, due to their unique characteristics. In the development of nanooptics science, it can be said that metal nanoparticles play an important role. The ability of conductive electrons collective oscillation causes surface charge density fluctuations in nanoparticles, this phenomenon is known as surface plasmons. Surface plasmons are surprisingly coupled with light and cause the significant increase in the intensity of optical fields induced in nanoparticles. Therefore, with the presence of localized surface plasmons or plasmon... 

    Theoretical Investigation of Ab-initio MD Approach to Increase the Efficiency and Accuracy of VCD Spectrum Calculation

    , M.Sc. Thesis Sharif University of Technology Hadi, Hossein (Author) ; Jamshidi, Zahra (Supervisor)
    Abstract
    Understanding of the Molecules is the main purpose of the chemistry. Ab-initio molecular dynamics (AIMD) as a branch of the computational chemistry, tries to give us a deep comprehension of the molecule, and its chemical, physical and optical activities. This comprehension, relies on the accuracy of quantum mechanics, in addition to the speed of the classical mechanics. The mixing of the quantum mechanics and the classical mechanics could simulate activities of the atoms in the time-domain, provided the mixing is done with precaution. This, in turn, helps us to forecast the response of a molecule in different situations, and also translating the macroscopic phenomena in a nanoscopic... 

    Investigation of Plasmonic Excitation in Carbonic Nanostructures Within Near-IR

    , M.Sc. Thesis Sharif University of Technology Madadi, Mahkam (Author) ; Jamshidi, Zahra (Supervisor)
    Abstract
    To date, the plasmonic properties of many metallic and semi-conducting materials have been investigated and used in various industries. One of the plasmonic material categories that have always been considered is polycyclic aromatic hydrocarbon or PAH, whose plasmonic resonance energy depends on the charge state of the molecule. In this regard, it is easy to change the plasmonic resonance energy via changing the induced charge, which is a unique feature of the mentioned materials. In addition, plasmonic structures with excitations in the infrared region are able to enhance the vibration intensity of absorbed molecules by increasing the electric field around themselves. Therefore, they have... 

    Using Simulation-Optimization Approach for Fire Station Location and Vehicle Assignment Problem: a Case Study in Tehran, Iran

    , M.Sc. Thesis Sharif University of Technology Pirmohammadi, Ali (Author) ; Amini, Zahra (Supervisor)
    Abstract
    In this research, the problem of locating fire stations and allocating equipment has been studied and a simulation-optimization approach has been presented to solve the problem. The mathematical models of this research were developed based on the idea of the randomness of the covered demand and the maximum expected coverage model. In these models, the issue of non-availability of equipment to cover accidents, the random nature of accidents, various fire incidents and the equipment needed to cover them are considered. Two mathematical models with deterministic and non-deterministic approach with different scenarios for demand are proposed. The non-deterministic model is developed with the aim... 

    Introducing An Integrated Framework For Solving The Fleet Planning Problem Using A Simulation-Optimization Approach

    , M.Sc. Thesis Sharif University of Technology Sahebi, Armin (Author) ; Amini, Zahra (Supervisor)
    Abstract
    One of the main concerns of industrial companies’ managers is providing an efficient logistics system. To achieve an efficient logistics system, the fleet planning problem is studied by many researchers in recent years. This problem consists of multiple sub-problems at three levels: operational, tactical, and strategic. These sub-problems are closely related to each other and need to be studied and addressed in an integrated manner. In this research, an attempt is made to provide an integrated framework to solve the vehicle routing problem (operational), outsourcing problem (tactical), and fleet composition problem (strategic). These problems have various uncertainties, including customer... 

    A Survey on Searchable Symmetric Encryption Schemes

    , M.Sc. Thesis Sharif University of Technology Sajadieh, Zahra Sadat (Author) ; Khazaei, Shahram (Supervisor)
    Abstract
    Using “Searchable Encryption” enables us to encrypt the data, while preserving the possibility of running search queries. One of the most important applications of the mentioned is in Cloud Storage. As users do not trust the Cloud space, they are not inclined to store their data on the Could. The solution to this problem is of course, Cryptography. However, ordinary Cryptography methods, eliminate the data’s searchability. Hence, we need encryption schemes that code the data while retaining their searchability. So far, various schemes has been proposed that differ in their performance, security level, and usage. In this thesis, we aim to discuss and analyze these methods  

    Temporal Depth Imaging Based on Dispersion

    , M.Sc. Thesis Sharif University of Technology Behzadfar, Shiva (Author) ; Kavehvash, Zahra (Supervisor)
    Abstract
    In this thesis, the aim is designing an optical temporal imaging system. In recent years, due to many applications, including the receipt of high-rate data by slow receivers and compensation of dispersion in telecommunication systems, researchers have considered the topic of temporal imaging. This field of research is based on dispersion, electro-optical modulators or time lenses and space-time theory. By modeling dispersion properties as a depth dimension and taking ideas from three-dimensional spatial imaging systems we intended to increase the temporal resolution and depth of focus of the structure. We also present a novel technique for multiplexing and demultiplexing telecommunication... 

    Time Domain Optical Signal Processing Based on the Duality Between Dispersion and Diffraction

    , M.Sc. Thesis Sharif University of Technology Eksiri, Fatemeh (Author) ; Kavehvash, Zahra (Supervisor)
    Abstract
    In the last decades, due to the growing demand of transferring information with high transmission rates, the complexity and development of telecommunication and optical systems is remarkable. Researchers around the world attempt to explore extraordinary potential of light to process information. In the mid-19th century, scientists discovered a mathematical symmetry between the spatial and temporal optics fields, which originated from the similarity of equations governing the paraxial diffraction of beams and the dispersion of narrow-band pulses known as space– time duality in scientific texts. This new approach provides more advanced and potent methods to temporal processing and... 

    Improving the Stability of an Urban Traffic Network with Limited Data by Using Percolation Theory and Dynamic Clustering

    , M.Sc. Thesis Sharif University of Technology Hassanzadeh, Ehsan (Author) ; Amini, Zahra (Supervisor)
    Abstract
    One of the most vital aspects of understanding the traffic phenomenon is scrutinizing the traffic transition status, such as the transition from free flow to congestion. The Percolation Theory is a renowned theory focusing on analyzing various network types to detect the critical zones, which are the zones including links that are important to control to improve stability. By calculating the quality indices of network links, the Percolation Theory can simulate the traffic percolation propagation in the network and determine possible critical zones for further analysis. Most studies in this field assume access to data of several traffic parameters for the entire transportation network, such... 

    Modification of Biomedical Imaging Methods in Short Wavelength Infrared Window

    , Ph.D. Dissertation Sharif University of Technology Hassan Abbasi (Author) ; Kavehvash, Zahra (Supervisor)
    Abstract
    In recent years, optical biomedical imaging techniques show great potential in noninvasive imaging. Although these methods have many advantages over other biomedical imaging methods (such as Computerized Tomography (CT), Magnetic Resonance Imaging (MRI) and etc.), these techniques confront with some problems such as optical scattering, light absorption and etc. For in vivo imaging, the short-wavelength infrared region (SWIR; 1,000–2,000 nm) provides several advantages over the visible and near-infrared regions: general lack of auto-fluorescence, low light absorption by blood and tissue, and reduced scattering. In this thesis we want to analyze the traditional IR imaging techniques and... 

    Upgrading the Ultrasound Imaging System Based on The Implementation of the Strain Imaging Mode

    , M.Sc. Thesis Sharif University of Technology Fathi, Haniyeh (Author) ; Kavehvash, Zahra (Supervisor)
    Abstract
    Strain imaging is a non-invasive ultrasound modality for assessing cardiac function in echocardiography systems. In this thesis, we implemented a fully automated strain imaging system containing 5 steps: 1) echocardiographic view recognition, 2) cardiac cycle phase detection, i.e., the events of end-diastole (ED) and end-systole (ES), 3) segmentation of left ventricular (LV) myocardium, 4) motion estimation of this wall and 5) strain calculation. In this work, we propose a novel deep learning-based framework for phase detection of cardiac cycle by the use of echocardiographic images in multibeat videos. Further, by applying the augmentation technique, the model has been able to detect events... 

    Analytical Modelling and Optimization of Disk Type, Slot Less Resolver

    , M.Sc. Thesis Sharif University of Technology Moheyseni, Atefeh (Author) ; Nasiri Gheidari, Zahra (Supervisor)
    Abstract
    Resolvers, due to their robust structure, are widely used in automation systems. Among the types of resolvers, the accuracy of the Wound Rotor (WR) resolver in the occurrence of common mechanical errors is higher than other types of resolvers. therefore, in this thesis, an AFWRR is studied to improve the performance. Increasing the number of poles in WR resolvers is a good solution for increasing the accuracy of these electromagnetic position sensors. However, high-speed WR resolvers due to employing fractional slot windings suffer from rich sub-harmonics in the induced voltages. A common solution for suppressing the undesirable sub-harmonics is using multi-layer winding with appropriate... 

    Characterizing an Environment from Visibility Information

    , M.Sc. Thesis Sharif University of Technology Emamy, Zahra Sadat (Author) ; Zarei, Alireze (Supervisor)
    Abstract
    Using visual information of an environment is the immediate way of detecting and identifying an unknown environment. These information maybe obtained using straight visibility detecting sensors. One of the formal models of these visual information is the visibility graph which have a vertex for each vertex (corner point) of the environment and two vertices have an edge whenever their corresponding corners see each other. Then, the problem is to characterize such a graph and reconstruct the target environment with equivalent visibility graph. Despite existence of plenty of research results, these are open problems in computational geometry and rigid results exist only for limited special... 

    Econometric Model of Housing Prices

    , M.Sc. Thesis Sharif University of Technology Mirmohamadali, Zahra Sadat (Author) ; Kiyanfar, Farhad (Supervisor)
    Abstract
    Housing is among the most primary fundamental needs of the household ,which consumes a high Proportion of the household expenditure and therefore it remains An important topic in macro economical analysis. Estimating and determining housing prices in different urban , areas is also important for planning .Estimations are also use in many decision making and process for the urban , regional , public, privet and organizational policy making. Due to the heterogeneity housing prices and the fact that it’s prices are affected by it’s characteristics , in this research housing prices of a few regions in tehran metropoly are assessed by the hedonic price model using macro and micro... 

    Design, Analysis, and Prototyping of Linear Variable Reluctance Resolver

    , M.Sc. Thesis Sharif University of Technology Daniar, Ahmad (Author) ; Nasiri-Gheidari, Zahra (Supervisor)
    Abstract
    Linear position sensors are widely used in linear motion-control systems. In this thesis, the design, optimization, performance analysis, and prototyping of a linear variable reluctance, variable air-gap length resolver are discussed. The accurate modelling of the studied sensor needs three-dimensional (3-D) time stepping finite element analysis (TSFEA) that is computationally expensive and unsuitable for co-usage with optimization algorithms. Therefore, the aim of this thesis is to establish an accurate, yet computationally fast, model suitable for optimal design of linear variable reluctance resolvers. The proposed mathematical model is presented based on modified winding function method. ...