Sharif Digital Repository

Chemotherapy is a proven and effective systematic approach to treat various types of cancers. Despite its advantages, chemotherapy would kill healthy as well as cancer cells. To overcome this problem, different controlling strategies are implemented. This study aims to provide a medicine drug delivery schedule for chemotherapy (by designing a proper controlling system) based on the verifiable mathematical models. First, the dynamic model is analysed and stability points are reviewed. The selected model has five state variables and two inputs. In this study, the focus is on dynamic model analysis and obtaining an effective and appropriate treatment pattern by designing a proper controller. To... 

Due to the vulnerability of urban fabric and residential buildings to earthquakes and considering its destructive social and economic effects on society, the need to adopt appropriate policies to prevent and reduce vulnerability, has been increasingly considered by policy makers. Despite the laws, regulations, incentives and penalties that policymakers have envisioned to prevent unprincipled and unsafe construction, evidence shows that a significant number of new buildings being built in the country are not earthquake resistant and there are many violations in design, implementation and supervision that is done by the stakeholders. To solve this problem, research has been done on the... 

The objective of this study is development of a probabilistic framework that facilitates the investigation of the post-earthquake performance of a network of hospitals using the Hospital Network Resilience index which quantifies the ability of the hospitals to provide treatment to earthquake victims. Disasters such as earthquakes can damage the infrastructure systems of a community, disrupt the functionality, and lead to various direct and indirect economic, social and socioeconomic consequences. Over a decade, natural disasters such as earthquakes are estimated to have caused $1.3 trillion economic losses. The social and socioeconomic losses of natural disasters are equally significant as... 

As a result of technology advancement in composite materials and the growth of analytical tools, applications of these materials is increasing in various industries, especially in aerospace industry. One of the structures developed using these materials is hybrid structure with composite/elastomer layering. Stress analysis and study of free-edge effect in this type of structures is possible by using three-dimensional elasticity in composite layers as well as nonlinear hyperelasticity in elastomeric layers, and this is the topic that this thesis deals with. The proposed approach to solving the problem is that the composite/elastomer hybrid structure is first analyzed by the finite element... 

Nowadays, economical extraction of oil and gas, and their products is an important issue for many countries. Up to now, vertical wells have been used for oil extraction but some wells exist that they cannot be reached by using vertical drilling; for example the wells under a sea. Therefore, this makes the governments and scientists determined to find a new way to reach them. Horizontal drilling is one of the new ways to reach such worthy wells. In this project, dynamics of the horizontal drill string is studied. Then, according to the forces that affect the dynamics of drilling, its vibration is analyzed. After finding the boundary conditions and normal modes of the system with using mode... 

Due to largre number of patients treated by dialysis and its significant increasing progress, dialysis efficiency and patients' life quality are of great interest.Dialyzer, the dialysis beating heart, has the role of cleaning blood by removing toxic solutes and balancing volume of bood's water through hollow fiber membranes. In this thesis, firstly we tried to focus on performance characteristics of dialyzer by studying effective parameters influencing dialyzer efficiency and ultimately we set two important performance characteristics, ultrafiltration coefficient and solute clearance, as our goal parameters for evaluating dialyzer's yield. To this purpose, we designed an experimental set... 

Air conditioning systems are one of the main parts of buildings, and their performance is very important, especially during the peak heat and cold days, both in terms of providing comfort area for the people and in terms of energy consumption. These systems control the temperature and humidity inside one or more target zones using heating, cooling, humidification, and dehumidification processes. One of the most common solutions to optimize the performance of air conditioning systems is the use of control systems. In this study, a nonlinear multi input-multi output dynamic model of a two-zone variable air volume & temperature air handling unit is considered for operation in the summer season.... 

Renewable energies and their various types have been recognized as sustainable solutions to address the challenges arising from increasing energy consumption and environmental issues. The use of wind energy as one of the renewable energy sources has particular advantages, considering it as one of the most sustainable energy sources. One of the key factors in wind turbine development is the diversity and multiplicity in their structural designs. Therefore, the design of wind turbine structures with characteristics such as suitable strength, high energy efficiency, optimal cost, and high reliability is of great importance. By employing various sciences such as vibrations and optimization in... 

The purpose of this study is to present a suitable model for calculating the costs imposed on society due to deaths and injuries due to infrastructure failure due to earthquakes, which is used in the analysis of community resilience. Much research has been done to date to calculate the economic costs of infrastructure failure. However, no suitable analytical framework has been provided to quantify the costs of deaths and injuries to people due to earthquake failure. Previous research has provided methods such as the value of statistical life to quantify the social costs caused by accidents and environmental pollution. However, the literature review results in the field of seismic resilience... 

In this thesis, we provide a comprehensive overview of the efforts made towards achieving the goals of Hilbert’s program, and evaluate how successful They are. We begin by discussing Gödel’s incompleteness theorems, and then as a first attempt we present a brief presentation of Gentzen’s consistency theorem. Subsequently, various research fields that branched out from these initial efforts are explored, encompassing the application of the Omega-Rule, reverse mathematics, and self-verifying systems. Furthermore, we present the concept of “Almost Finitistic Consistency” as an alternative approach within Hilbert’s program. In conclusion, a thorough assessment of the success of Hilbert’s program... 

Question answering systems are systems which get a question in natural language as input and present an explicit, appropriate answer to the question. One of the major components of automatic question answering systems is question processing component in which the input question is analyzed. The main goal of question processing phase is to determine the answer type through question classification. Rule-based, machine learning-based and hybrid approaches have been used in order to develop question classifiers among which machine learning-based ones have outperformed the others. This study’s main goal is to develop a question classifier for Persian open domain question answering systems.... 

Exoskeletons, or wearable robots, are electromechanical devices that have become the focus of academic and industrial research in recent years, and their applications in power augmentation have increased. One of the most important challenges of these applications is controlling the robot and synchronizing it with the user. The close interaction of the robot with the user and the change of movement pattern between different users and different gait cycles show the importance of estimating the user's movement intention, but the need for online method of estimating the movement intention and the complexity of accurate dynamic modeling has caused researchers to use reinforcement learning (RL) in... 

Digital video is one of the biggest part of digital data. The first step of digital video analytics is shot boundary detection. We used overlapped partitioning beside color histogram in uncompressed data and macroblock type prediction in compressed data as feature and supervised classifiers for decision making. Tests on TRECVID 2006 shows 8.9% improvement of F-measure in uncompressed video and 5.3% in h.264 bitstream. Supplementary test is done on IRIB dataset which shows 5.7% improvement of F-measure in uncompressed and 3.2% in H.264. H.264 based algorithm is almost 7 times faster in comparison to the algorithm that includes decoding  

Due to the increasing spread of metal industries and the need for raw material as feed for electric furnaces in order to produce cast iron and steel, as well as scrap deficiency and rising prices, the use of sponge iron as a substitute for scrap was considered in this project Therefore, in order to achieve the chemical analysis of the sorel ingot that is special for spherical graphite cast iron production with low manganese and chromium content, the direct reduction process was carried out using tunnel kiln method on low-manganese iron ore concentrate.After the investigation on direct reduction parameters including the saggers and coal grading,the produced sponge iron has melted in... 

Throughout history, the occurrence of natural disasters and incidents has posed a potential threat to man-made constructions. Advancements in science and technology have led to the development of man-made civil infrastructures, which now exhibit increased complexity in terms of technological sophistication and spatial coverage. Consequently, monitoring and managing their health and risk factors have become more intricate. Urban lifelines, which encompass constructed utilities, transportation systems, telecommunication networks, and critical facilities, hold significant importance for the well-being of citizens. These infrastructure assets are essential for the distribution and flow of... 

Fuel system is one of the most important parts of pulse detonation engine which has the responsibility of fuel, oxidizer and also purge gas in the different operational frequencies of engine. Although pulse detonation engines are sort of air breathing engines and purge gas and oxidizer one in the same unit in their structure, due to existence idea in the pulse detonation rocket engines coverage of functional condition, fuel, oxidizer and purge gas, will study it in three different structures.
In this study purpose is improvement of the pulse detonation engine of Sharif University which will provide as the possibility of safe functional condition and high operational frequency in... 

Auction is one of the most important and oldest institutions in economics, enabling resource allocation and trade of goods in the economy. Investigating the effects of changes in reservation price in auctions is an important question in auction theory research. In this study, focusing on a policy implemented by Yektanet, which involved altering the reservation price in auctions for advertising slots, we assessed its impact on advertiser costs. The implemented policy led to the activation of two distinct mechanisms, resulting in conflicting effects on the company's revenue. The first mechanism involved an increase in bid and intensified competition for ad placements on average, while the... 

Nowadays, applications of industrial robots are significantly increasing due to their flexibility, programmable, accuracy, rapidity and etc. Among these, machining robots play an important role at manufacturing industries. One of the main concerns of the researchers, is the tip vibrations of robot arms. In most times, these vibrations are self-excited, unpredictable and intolerable. Thus, finding a method for reducing vibration should be investigated. The purpose of vibration control is vibration suppression to enhance the reliability of the system. The aim of this project is the modeling of the machining robot arm in turning process and then application of robust control to reduce... 

Epistemic logic gets its start with the recognition of the systematic properties of epistemic concepts. These properties make epistemic concepts amenable for formal study, and become our tools to present logical models for them.“Certainty” is one of these epistemic concepts for which no comprehensive logical model has been presented so far.
Among the logical models that have been presented for “Certainty”, there are two main models which are more comprehensive than the others and all the other models may be extendable to one of them. In this thesis, these two main logical models that have been proposed for the concept of certainty are introduced and described from a philosophical...