Sharif Digital Repository

Nanoparticles for biomedical use must be cytocompatible with the biological environment that they are exposed to. Current research has focused on the surface functionalization of nanoparticles by using proteins, polymers, thiols and other organic compounds. Here we show that inorganic nanoparticles such as titanium oxide can be coated by pyrolytic carbon (PyC) and that the coating has cytocompatible properties. Pyrolization and condensation of methane formed a thin layer of pyrolytic carbon on the titanium oxide core. The formation of the PyC shell retards coalescence and sintering of the ceramic phase. Our MTT assay shows that the PyC-coated particles are cytocompatible at employed doses  

Modelling a proper stochastic inflow wind field for dynamic analysis of an offshore wind turbine (OWT) is affected by turbine specifications and wind characteristics. These considerations and assumptions could potentially have a significant effect on the motions and structural loads and dynamic responses of the system. Previous studies have investigated the impact of various parameters-such as yaw misalignment, aerodynamic properties, blade mass imbalance, turbulence spectra, shear, veer, spatial coherence, component correlation, ant etc.-which could vary at different offshore sites and under different atmospheric conditions. Among different influencing factors in modelling the turbulence... 

This paper introduces a new class of interconnection networks named star-pyramid. An n-level star-pyramid is formed by piling up star graphs of dimensions 1 to n in a hierarchy, connecting any node in each i-dimensional star, 1 < i ? n, to a node in the (i - 1)-dimensional star whose index is reached by removing the i symbol from the index of the former node in the i-dimensional star graph. Having extracted the properties of the new topology, featuring topological properties, a minimal routing algorithm, a simple but efficient broadcast algorithm, Hamiltonicity and pancyclicity, we then compare the network properties of the proposed topology and the well-known pyramid topology. We show that... 

This paper introduces a new class of interconnection networks named star-pyramid. An n-level star-pyramid is formed by piling up star graphs of dimensions 1 to n in a hierarchy, connecting any node in each i-dimensional star, 1 < i ≤ n, to a node in the (i - 1)-dimensional star whose index is reached by removing the i symbol from the index of the former node in the i-dimensional star graph. Having extracted the properties of the new topology, featuring topological properties, a minimal routing algorithm, a simple but efficient broadcast algorithm, Hamiltonicity and pancyclicity, we then compare the network properties of the proposed topology and the well-known pyramid topology. We show that... 

In this paper, we propose a new approach in computing interference distribution and outage probability for uplink CDMA cellular networks. In this approach, we model time-varying interference as a discrete-time Markov chain with flexible approximation and find its steady state distribution. Our approach is based on tracing the time variation of the effective factors in interference such as spatial locations, activity status, and shadowing status for the connected users. To this end, we approximate shadowing with several discrete levels by Lloyd algorithm. Moreover, we incorporate correlation properties of the shadowing status in our model. Then, we map the effective factors onto the... 

This paper presents a new ADC based on using passive charge sharing SAR ADC in a 2-stage pipeline architecture. The charge domain operation of passive charge sharing ADC poses an inherent limitation on its resolution. The proposed architecture increases the achievable resolution with a low power overhead. Designed and simulated in a 0.18um CMOS process, the 12-bits, 40MS/sec ADC core consumes 7mW from a 1.8V supply  

This paper introduces a new class of interconnection networks named Star-Pyramid, SP(n). A star-pyramid of dimension n is formed by piling up star graphs of dimensions 1 to n in a hierarchy, connecting any node in each i-dimensional star, 1< i ≤ n, to a node in (i - 1)-star whose index is reached by removing the i symbol from the index of the former node in the i-star graph. Having extracted the properties of the new topology, featuring topological properties, a simple routing algorithm and Hamiltonicity then we compare the network properties of the proposed topology and the well-known pyramid topology. We show that the star-pyramid is more fault-tolerant and has less network diameter than... 

Superparamagnetic iron oxide nanoparticles (SPIONs) are promising materials for various biomedical applications including targeted drug delivery and imaging, hyperthermia, magneto-transfections, gene therapy, stem cell tracking, molecular/cellular tracking, magnetic separation technologies (e.g. rapid DNA sequencing), and detection of liver and lymph node metastases. The most recent applications for SPIONs for early detection of inflammatory, cancer, diabetes and atherosclerosis have also increased their popularity in academia. In order to increase the efficacy of SPIONs in the desired applications, especial surface coating/characteristics are required. The aim of this article is to review... 

Superparamagnetic iron oxide nanoparticles (SPION) are being increasingly used in various biomedical applications such as hyperthermia, cell and protein separation, enhancing resolution of magnetic resonance imaging, and drug delivery. However, the toxicity data for SPION are limited. In this study, uncoated and single polyvinyl alcohol coated SPION with high chemical reactivity (due to the bigger surface area) were synthesized using a coprecipitation method. Cytotoxicity of these magnetic nanoparticles and their ability to cause arrest in cell life-cycles was investigated. Interaction of these nanoparticles with adhesive mouse fibroblast cell line (L929) was probed using MTT assay. High... 

The size mono-dispersity, saturation magnetization, and surface chemistry of magnetic nanoparticles (NPs) are recognized as critical factors for efficient biomedical applications. Here, we performed modified water-in-oil inverse nano-emulsion procedure for preparation of stable colloidal superparamagnetic iron oxide NPs (SPIONs) with high saturation magnetization. To achieve mono-dispersed SPIONs, optimization process was probed on several important factors including molar ratio of iron salts [Fe3+ and Fe2+], the  

Superparamagnetic iron oxide nanoparticles (SPIONs) are increasingly used in medical applications, such as targeting delivery and imaging. In the future, patients are more likely to be exposed to pharmaceutical products containing such particles. The study of toxicity of SPIONs has become of great importance in recent years, although the published data in this arena is limited. The aim of the present work is to investigate the cytotoxicity of SPIONs and the effect of the particles on the cell medium components. For this purpose, uncoated and polyvinyl alcohol (PVA) coated SPIONs with narrow size distribution were synthesized via a well-known coprecipitation method. The mouse fibroblast cell... 

The utilization of the limited resources of a multiprocessor or multicomputer system is a primary performance issue which is crucial for the design of many scheduling algorithms. While many of the existing parallel machines benefit from a regular product network topology, almost none of the previous resource placement techniques have come to recognize and exploit this inherent regularity. This paper introduces several novel algorithms for deriving resource placement schemes in product networks based on the assumption of perfect resource placement in their underling basic graphs. Our techniques use known schemes for the basic networks as their building blocks for deploying the resource... 

Superparamagnetic iron oxide nanoparticles (SPIONs) are promising materials for various biomedical applications including targeted drug delivery and imaging, hyperthermia, magneto-transfections, gene therapy, stem cell tracking, molecular/cellular tracking, magnetic separation technologies (e.g. rapid DNA sequencing), and detection of liver and lymph node metastases. The most recent applications for SPIONs for early detection of inflammatory, cancer, diabetes and atherosclerosis have also increased their popularity in academia. In order to increase the efficacy of SPIONs in the desired applications, especial surface coating/characteristics are required. The aim of this article is to review...