Sharif Digital Repository

Varus-valgus deformity is the improper alignment of lower extremities, which results in the increment of the local stress within the cartilage and the consequent alteration of the performance mechanism of the soft tissues around the knee joint. This accounts for changes within the movement pattern and thus further deformities, which, when continued, can lead to more serious damage in the form of osteoarthritis. The aforementioned cycle can be prevented through the conduction ofosteotomy; a surgical procedure in which the addition or removal of a bone wedge can correct the improper alignment. The correct design and conduction of osteotomy in terms of the location, angle, and size of the... 

The Barrier of the internal rotation around C-N bond in O-ethyle morpholine-4-carbotioate were calculated using dynamic NMR spectroscopy (DNMR) in DMSO solvent. 1H and 13C NMR spectra were recorded at different temperatures (295-350K). Band shape broadening patterns at coalescence regions were simulated to extract rate constants of NMR spectera. Transition state thermodynamic properties of internal rotation around C-N bond in O- ethyle morpholine -4- carbotioate are estimated: , , , . To assay reliability of the estimated values, transition state thermodynamic properties were calculated using PCM model at method and basis set B3LYP/6-311++G(d,p). Theoretical values of thermodynamic... 

Damming projects always have been important while construction, operation and even demolition due to their major effects on society, environment and economy. Although researchers have focused on one or a few phases of construction projects to develop sustainable infrastructures, the research community has to consider long term effects of developments too. There are a variety of such effects that ignoring them will cause construction of not convenient infrastructures i.e. air pollution and over-consumption of energy resources while construction, operation and demolition. Therefore, it is suggested to consider life cycle assessments to include all bad effects in all phases of a project. Dams... 

Connecting titanium and aluminum alloys is widely used in different industries such as transportation, chemical, aircraft manufacturing, etc. Friction stir welding is one of the methods of joining these two metals. In order to obtain a sound joint, the formation of intermetallic phases in the interface must be controlled. One of the ways to control these phases is the use of an interlayer, which in this research is the interlayer applied by plasma electrolytic oxidation method with different current densities and coating times. In this regards, first the optimal parameters of friction stir welding were determined. Then, Ti6Al4V and Al6061-t6 welding was performed in the presence of... 

Nowadays, advanced and inexpensive pre-clinical methods for investigating the effects of anti-cancer drugs are expanding. One of the latest three-dimensional laboratory modeling for evaluating the effects of drugs is the use of tumor-on-chip technology, which actually models the physiological system of the body through three-dimensional scaffolds, multicellular cultures, and shaped vascular systems. In this study, three-dimensional culture of cancer cells was performed in the form of spheroids. A chip of U-shaped microstructures with and without gaps was used to trap cells and form cancer spheroids. We simulated the simultaneous effect of drug and oxygen concentration distribution inside the... 

Growing need for the use of modern technologies in the field of information and communication reveals the necessity to establish an information security management system more than before. It is totally proven that information is an asset which, like other important assets of the organization is so momentous that should be crucially protected. Nowadays, with the proliferation of security threats, which can lead to undesirable events with possible damage to systems or organizations intentionally or inadvertently, by human factors or inhuman cause, existence of a safe structure has become more necessary for all organizations and agencies. One of the most critical areas of information security... 

One of the most critical problems in medical supply chain is tracking the pharmaceutical throughout the chain. The challenging solution is to use of barcodes which has numerous limits. Radio frequency identification (RFID) tools are the next generation of barcodes that provide more convenient and faster track of supplies. With automatic workplace, the precision of the system is increased and less personnel is needed. In this study, various medical supply chain management procedures were studied for a hospital and the most appropriate procedure was chosen. According to the hospital conditions, RFID over barcode was the procedure of choice. In order to validate this choice, the ARENA software... 

Modeling and performance evaluation of the real time distributed systems is a significant problem. Stochastic activity network is one of the high level models used for this purpose. This network is an extension of generalized stochastic Petri net which is more powerful and flexible than other Petri net extensions. Checking the satisfiability of properties such as performance, dependability and user's expected properties is considerable in these models. Thus, using the approaches and generating modeling and model checking tools with the mentioned purpose is attractive. A model checker automatically checks the correctness of the system behaviors as properties against the model by getting the... 

This study has focused on the important problem of landing on a planet as an important current and future space mission. In this regard, dynamics modeling and integrated state estimation and control problems have been investigated in different views. To this aim, first a novel concurrent representation for translational and rotational kinematics has been developed based on the extension of modified Rodrigues parameters to dual space. This parameter set, called dual modified Rodrigues parameters (DMRP), is then utilized to establish an integrated roto-translational dynamic. The proposed DMRP-based kinematics and dynamics have been verified via comparison to traditional methods of...