Loading...
Search for:
jamaati--sayna
0.034 seconds
Development of Software Based on Statistical Iterative Algorithm in the Reconstruction of Sparse View CT images
, M.Sc. Thesis Sharif University of Technology ; Hosseini, Abolfazl (Supervisor)
Abstract
X-ray Computed Tomography (CT) is a widely used medical imaging technique that provides cross-sectional images by measuring the attenuation of X-rays in the body. However, the increasing use of CT has raised concerns about the potential long-term risks associated with radiation exposure. Various approaches have been proposed to reduce radiation dose, and one of the latest methods is sparse-view CT, which has gained popularity due to its lower challenges compared to other techniques. In sparse-view CT, data acquisition is restricted to specific angles, resulting in a significant reduction in radiation dose. However, this approach can introduce streak artifacts in the reconstructed images due...
Optimization of Insulin Releasing from Hydrogel Encapsulated Beta Cells
, M.Sc. Thesis Sharif University of Technology ; Alemzadeh, Iran (Supervisor) ; Vosoughi, Manouchehr (Co-Supervisor)
Abstract
Beta cells are responsible for secreting insulin to maintain normoglycaemia throughout the individual’s life. Type 1 Diabetes Mellitus (T1DM) is a metabolic disorder characterized by an autoimmune response that promotes the destruction of beta-cells within the pancreatic islets, resulting in lifelong inadequate insulin secretion. Encapsulating beta cells inside a semipermeable membrane to protect encapsulated cells from direct contact with the host immune system, is a new way to treat type 1 diabetes without the need for long-term immunosuppression. . In this case, the semipermeable membrane surrounds the cells and allows oxygen, nutrients, and cell products to penetrate bilaterally while...
Role of shear stress in ventilator-induced lung injury
, Article The Lancet Respiratory Medicine ; Volume 4, Issue 8 , 2016 , Pages e41-e42 ; 22132600 (ISSN) ; Nazari, M ; Darooei, R ; Ghafari, T ; Raoufy, M. R ; Sharif University of Technology
Lancet Publishing Group
2016
The olfactory bulb modulates entorhinal cortex oscillations during spatial working memory
, Article Journal of Physiological Sciences ; Volume 71, Issue 1 , 2021 ; 18806546 (ISSN) ; Tabasi, F ; Nazari, M ; Ghazvineh, S ; Salimi, A ; Jamaati, H ; Raoufy, M. R ; Sharif University of Technology
BioMed Central Ltd
2021
Abstract
Cognitive functions such as working memory require integrated activity among different brain regions. Notably, entorhinal cortex (EC) activity is associated with the successful working memory task. Olfactory bulb (OB) oscillations are known as rhythms that modulate rhythmic activity in widespread brain regions during cognitive tasks. Since the OB is structurally connected to the EC, we hypothesized that OB could modulate EC activity during working memory performance. Herein, we explored OB–EC functional connectivity during spatial working memory performance by simultaneous recording local field potentials when rats performed a Y-maze task. Our results showed that the coherence of delta,...
Rhythmic air-puff into nasal cavity modulates activity across multiple brain areas: A non-invasive brain stimulation method to reduce ventilator-induced memory impairment
, Article Respiratory Physiology and Neurobiology ; Volume 287 , 2021 ; 15699048 (ISSN) ; Salimi, M ; Nazari, M ; Garousi, M ; Tabasi, F ; Dehdar, K ; Salimi, A ; Jamaati, H ; Mirnajafi Zadeh, J ; Arabzadeh, E ; Raoufy, M. R ; Sharif University of Technology
Elsevier B.V
2021
Abstract
Mechanical ventilation (MV) can result in long-term brain impairments that are resistant to treatment. The mechanisms underlying MV-induced brain function impairment remain unclear. Since nasal airflow modulates brain activity, here we evaluated whether reinstating airflow during MV could influence the memory performance of rats after recovery. Rats were allocated into two study groups: one group received rhythmic air-puff into the nasal cavity during MV and a control group that underwent ventilation without air-puff. During MV, air-puffs induced time-locked event potentials in OB, mPFC and vHPC and significantly increased the oscillatory activity at the air-puff frequency. Furthermore, in...
Allergic rhinitis impairs working memory in association with drop of hippocampal – Prefrontal coupling
, Article Brain Research ; Volume 1758 , 2021 ; 00068993 (ISSN) ; Ghazvineh, S ; Nazari, M ; Dehdar, K ; Garousi, M ; Zare, M ; Tabasi, F ; Jamaati, H ; Salimi, A ; Barkley, V ; Mirnajafi Zadeh, J ; Raoufy, M. R ; Sharif University of Technology
Elsevier B.V
2021
Abstract
Allergic rhinitis (AR) is a chronic inflammatory disease frequently associated with a deficit in learning and memory. Working memory is an important system for decision making and guidance, which depends on interactions between the ventral hippocampus (vHipp) and the prelimbic prefrontal cortex (plPFC). It is still unclear whether AR influences the activity and coupling of these brain areas, which consequently may impair working memory. The current study aimed to examine alterations of the vHipp-plPFC circuit in a rat model of AR. Our results show decreased working memory performance in AR animals, accompanied by a reduction of theta and gamma oscillations in plPFC. Also, AR reduces...
Asthma induces psychiatric impairments in association with default mode and salience networks alteration: A resting-state EEG study
, Article Respiratory Physiology and Neurobiology ; Volume 300 , 2022 ; 15699048 (ISSN) ; Salimi, M ; Nazari, M ; Tabasi, F ; Bamdad, S ; Dehdar, K ; Mikaili, M ; Mahdaviani, S. A ; Salari, F ; Lookzadeh, S ; Jamaati, H ; Salimi, A ; Raoufy, M. R ; Sharif University of Technology
Elsevier B.V
2022
Abstract
Asthma is a chronic inflammatory disease associated with a high prevalence of psychiatric disorders. There are specific brain networks responsible for emotional processes, including two important networks associated with psychiatric problems: the default mode network (DMN), which is more active in the resting state, and the salience network (SN), which is structurally connected to DMN. Although previous studies suggested that neuro-phenotypes of asthma may be recognizable by the neural activity of brain circuits, an association between the brain's functional alterations and psychiatric impairments induced by asthma remains unknown. We aimed to assess DMN and SN activity and its association...
Allergen-induced anxiety-like behavior is associated with disruption of medial prefrontal cortex - amygdala circuit
, Article Scientific Reports ; Volume 9, Issue 1 , 2019 ; 20452322 (ISSN) ; Mahdidoust, S ; Salimi, M ; Gholami Mahtaj, L ; Nazari, M ; Mohammadi, S ; Dehghan, S ; Jamaati, H ; Khosrowabadi, R ; Nasiraei Moghaddam, A ; Barkley, V ; Javan, M ; Mirnajafi Zadeh, J ; Sumiyoshi, A ; Raoufy, M. R ; Sharif University of Technology
Nature Research
2019
Abstract
Anxiety is prevalent in asthma, and is associated with disease severity and poor quality of life. However, no study to date provides direct experimental evidence for the effect of allergic inflammation on the structure and function of medial prefrontal cortex (mPFC) and amygdala, which are essential regions for modulating anxiety and its behavioral expression. We assessed the impact of ovalbumin (OVA)-induced allergic inflammation on the appearance of anxiety-like behavior, mPFC and amygdala volumes using MRI, and the mPFC-amygdala circuit activity in sensitized rats. Our findings exhibited that the OVA challenge in sensitized rats induced anxiety-like behavior, and led to more activated...