Sharif Digital Repository

Casing collapse is a long-standing problem in Kopal oil field, located at a distance of 60 km of east of Ahwaz, Iran. In this field, so far casing collapse has encountered in 18 well-bore out of the 56 drilled-well-bore (~32%) due to creep loading caused by salt flow, which resulted in tremendous economic loss. Among all the different set of factors leading to such a problem, the effects of the local stress distribution on the wellbore wall and casing (resulted from the in-situ stresses, and stress perturbation due to drilling), pore pressure, the casing quality and material, and the applied-cement type are important. In order to investigate these factors and their effects, they should be... 

Cancer is one of the most causes of mortality in the world. Leukemia is a type of cancer initiated by the rapid proliferation of blood cells including WBCs, RBCs, and Platelets, that classified into four general types of AML, ALL, CML, and CLL. The main treatment of leukemia is chemotherapy. Because of many problems that patients have with this treatment and not so good results of chemotherapy, we design a microfluidic chip that can perform personalized medicine treatment for leukemia patients.This microchip consists of two main parts, Concentration Gradient Generator (CGG), and cell culture. CGG system is a tree CGG with two inlets and four outlets, which makes a linear concentration of... 

A bioreactor can refer to any device or system constructed on engineering basis and has an active biological medium. This medium includes aerobic and non-aerobic reactions in which organisms and the theire produced substances have the main role. One of the applications of bioreactors is to provide an appropriate medium for animal and plant cell culture and growth. Nowadays many biological processes in high volume scales are carried out in stirred tank bioreactors. In these bioreactors oxygen transfer is usually increased by increasing turbulence which is necessary for mixing nutrients and keeping the homogeneity of the medium. However, there are some limitations for increasing the stirring... 

Aerosols are significant two-phase systems that have an important effect on environmental, biological, health, industrial and other scientific and engineering fields. According to chief aerosol effects, various instruments namely “Aerosol Spectrometer” have been developed to measure aerosols. Optical Particle Counters (OPCs) are one of this instruments that can count and measure the particles size distribution in the aerosols.
In the current project, an optical particle counter has been designed. For validating the correct operation of the designed plan, it is needed to simulate the instrument optically and mechanically, so the Mie theory was used to simulate the intensity of the... 

Lab-On-A-Chip is a micro-scale system which utilizes specific tools in order to operate detection tests on samples. One of the most important components of these devices is micromixers which is responsible for appropriate mixing of samples in short period of time. The biggest problem associated to the mixing in micro-scale is the regime that the flow takes during the process. Due to the small dimensions of micromixers the induced flow stream resides in the range of laminar flows and consequently the mixing is conducted solely by diffusion mechanism which is either time-taking or requires long micro-channel that causes the high cost of fabrication. In order to improve the mixing process two... 

Investigation of the behavior of living cells in different biological conditions could play a key role in exploring the main reasons of humans' disorders and diseases. In this regard, many researchers are studying different subjects related to the living cells. Although most of these research activities are based on experimental methods, numerical approach could be utilized to investigate some topics which cannot be studied by experimental methods.In this study a three dimensional model of endothelial cell is proposed for the investigation of cell performance during compression test. The model consists of cell membrane, nucleus and main components of cytoskeleton, namely actin filaments,... 

To investigate boiling heat transfer characteristics of nanofluids, transient quenching¬ experiments of a high temperature silver sphere in water-based nanofluids with Ag and TiO2 nanoparticles were performed. A silver sphere of 10 mm in diameter at the initial temperature of 700o C was quenched in the nanofluids at the temperature of 90o C. The results showed considerable reduction in the quenching ability of nanofluids compared to that of pure water. The presence of nanoparticles in water caused film boiling mode to vanish at lower temperatures depending on the mixture concentration. Computed heat transfer rates in nanofluids were lower than those in pure water. In the quenching... 

One of the major issues raised in the numerical models is the effects of various input parameters on the model output. Identifying the most important parameters in the output is very important in petroleum engineering, especially in tuning equation of states and history matching. Screening the most important parameters from unimportant parameters is assessable by sensitivity analysis.In this study local and global sensitivity analysis methods are used to identify the most important parameters in tuning EOS for seven different fluid samples. Global sensitivity analysis methods are more successful in correct ranking of tuning parameters. Morris method as a global method can screen the... 

Due to popularity of mobile wireless devices, security of mobile ad hoc networks (MANETs) being more important than before. Traditional key management schemes based on symmetric key cryptography are became ineffective because of dynamic and infrastructureless nature of these networks.Recent studies are mainly based on traditional public key cryptography schemes and ID-based cryptography schemes. On the other hand, Contributory schemes seem suitable for MANETs because of their inherent self-organize property. Key update and Key revocation are the fundamental issues of key management schemes in mobile ad hoc networks. Certificateless public key cryptography, in addition to solve those issues,... 

One of the most important issues in modeling and simulation of reservoirs is determination of different rock types or Rock Typing. In this study, after a brief review of some conventional methods for rock typing, their capabilities have been investigated. In this way, for the first time, pore network modeling is used as a tool for validating the rock typing methods. By using flow simulation in porous medium with pore network modeling approach, similar rock types data have been generated and these artificially data have been used for validating of rock typing methods. To form more realistic pore networks, both regular and irregular pore network have been modeled and analyzed. Pore size... 

Alavand Oil field is located 50 Km away from west of Siri Island and includes DPG and DPH platforms. The production from Alavand field started in 1998 and till now 11 wells have been totally drilled .Since a production peak in 2001, the oil production in Alvand field has decreased. Water cut is increasing and reservoir pressure is decreasing gradually. Considering poor reservoir characteristic of this reservoir, productivity indexes of wells are relatively low. In addition; natural depletion of reservoir caused the wells to be unable to flow naturally and either closed or produce periodically consequently. To increase production and extend the lifetime of Alvand field, it is decided to start... 

Matrix acidizing aims at bypassing near wellbore damages in typical carbonate reservoirs or enhancing permeability and hydraulic conductivity in naturally fracture ones. The simulation of acidizing process at pore scale and complex geometries by LBM will lead to gain more knowledge about molecular mechanisms that govern rock dissolution, diffusion and advection of reactive fluid and help the evaluation of acidizing efficiency.In this thesis, simulation of acidizing includes the following steps:
• Multicomponent fluid convection
• Fluid diffusion into the solid
• Fluid-rock reaction
• Boundary conditions including periodic, bounceback, non-equilibrium bounceback, Dirichlet,...