Loading...
Search for: khalilian--hanieh
0.104 seconds

    Lithography-directed Self-assembly for Designing Drug Particles of Various Sizes and Morphologies

    , M.Sc. Thesis Sharif University of Technology Forghan Tarigheh, Fatemeh (Author) ; Safari, Hanieh (Supervisor)
    Abstract
    To design a drug delivery system, the drug must be encapsulated within a carrier matrix. One of the main challenges in this field is encapsulating high drug doses while achieving a linear release profile at the target site to maintain drug concentration for optimal therapeutic effects. Consequently, many research groups have focused on refining fabrication techniques to maximize loading efficiency and optimize drug release profiles from delivery systems. A potential approach to addressing this issue is the direct fabrication of a controlled-release system from the active pharmaceutical ingredient (API) itself, eliminating the need for a carrier matrix. Studies have demonstrated that such... 

    Estimation of data hiding capacity of digital video based on human visual model in temporal domain

    , Article 2nd International Conference on Signal Processing and Communication Systems, ICSPCS 2008, Gold Coast, QLD, 15 December 2008 through 17 December 2008 ; April , 2008 ; 9781424442423 (ISBN) Khalilian, H ; Ghaemmaghami, S ; Sharif University of Technology
    2008
    Abstract
    A new approach to evaluation of the data hiding capacity of digital video is presented in this paper. The paper reconsiders the conventional capacity estimation algorithms, in which the video signal is taken as a sequence of still images, that result in an exaggerated upper bound of hiding capacity or a much higher value than the actual embedding capacity. The proposed method for the capacity estimation is based on the human visual model in temporal domain, which leads to a more realistic, tighter bound for video capacity. In this method, according to temporal characteristic of every frame, a visibility based coefficient is extracted that is used to determine the hiding capacity. The maximum... 

    Development of Microextraction Methods
    for the Trace Determination of Organic Compounds in Biological and Environmental Media

    , Ph.D. Dissertation Sharif University of Technology Khalilian, Faezeh (Author) ; Bagheri, Habib (Supervisor)
    Abstract
    The approach of this thesis is to develop and simplify robust microextraction techniques and apply these developed methods to real samples and complex matrices. Firstly, a modified solvent microextraction with back extraction method (SME/BE) combined with high performance liquid chromatography and fluorescence detection (HPLC-FD) was developed for the determination of citalopram in human plasma. Extraction process was performed in a home-made total glass vial without using a teflon ring, usually employed in SME/BE. The evaluation results demonstrated that the calibration curve showed linearity in the range of 1.0–130.0 ng/mL which covers therapeutic window and even lower amounts which is... 

    Angle Shear Connectors Capacity

    , M.Sc. Thesis Sharif University of Technology Khalilian, Marzieh (Author) ; Maleki, Shervin (Supervisor)
    Abstract
    The steel-concrete composite beams are increasingly used in bridge and building construction in recent years. A shear connection between the steel and concrete should be provided to effectively transfer the shear force and to make the two materials act as a single unit. The mechanical shear connectors provide this means. They are the essential component of any composite beam system. Many studies have been performed on shear connectors and many different steel shapes have been suggested for connectors. The steel studs and channels are the most popular code accepted connectors. However, economic considerations continue to motivate the development of new products.
    Present knowledge of the... 

    Video Watermarking and Capacity Analysis: Information Theoretic Approach

    , M.Sc. Thesis Sharif University of Technology Khalilian, Hanieh (Author) ; Ghaemmaghami, Shahrokh (Supervisor)
    Abstract
    Data hiding in digital media has been widely investigated over the past decade because of covering different crucial applications. Amongst digital multimedia signals, video has been received a special attention and data hiding in video signals has reached a significant improvement in recent years. This thesis aims at introducing an information theoretic based analysis method for calculating the capacity of data hiding in video signals, as one of most challenging issues in this area. This analysis is expected to establish a reasonable basis for the design and analysis of data hiding algorithms. We study and investigate the data hiding problems that could be specific to video signals and its... 

    Impact of the Shape of the Loaded Particles on the Mechanical Properties of the Scaffolds and their Interaction with Macrophages

    , M.Sc. Thesis Sharif University of Technology Tymuri, Fatemeh (Author) ; Mashayekhan, Shohreh (Supervisor) ; Safari, Hanieh (Supervisor)
    Abstract
    Osteoarthritis is a common musculoskeletal disorder and the most prevalent form of arthritis. To date, no comprehensive cure has been reported for osteoarthritis, and its clinical management remains challenging. The primary therapeutic goals in the early stages of osteoarthritis are to increase joint mobility and control disease progression by continuously releasing drugs and molecules modulating inflammatory responses and reducing pain. Smart drug delivery platforms are one of the strategies to overcome the challenges of injectable and oral medications. Additionally, drug carrier particles can have different therapeutic targets based on their size and shape. Different therapeutic... 

    Immersed sol-gel based amino-functionalized SPME fiber and HPLC combined with post-column photochemically induced fluorimetry derivatization and fluorescence detection of pyrethroid insecticides from water samples

    , Article Journal of Separation Science ; Volume 32, Issue 17 , 2009 , Pages 2912-2918 ; 16159306 (ISSN) Bagheri, H ; Ghanbarnejad, H ; Khalilian, F ; Sharif University of Technology
    2009
    Abstract
    A method based on direct immersion solid-phase microextraction (DI-SPME) coupled with high performance liquid chromatography combined with post-column photochemically induced fluorimetry derivatization and fluorescence detection (HPLC-PIF-FD) was developed to extract three pyrethroid insecticides, i.e. cyfluthrin, cypermethrin, and flumethrin from water samples. A sol-gel based coating fiber using 3-(trimethoxysilyl propyl) amine as precursor was prepared and used for the extraction of the pyrethroids from groundwater samples. A post-column photochemical reactor was designed and constructed for the derivatization of these environmentally important pollutants to increase their fluorescence... 

    An interior needle electropolymerized pyrrole-based coating for headspace solid-phase dynamic extraction

    , Article Analytica Chimica Acta ; Volume 634, Issue 2 , 2009 , Pages 209-214 ; 00032670 (ISSN) Bagheri, H ; Babanezhad, E ; Khalilian, F ; Sharif University of Technology
    2009
    Abstract
    A headspace solid-phase dynamic extraction (HS-SPDE) technique was developed by the use of polypyrrole (PPy) sorbent, electropolymerized inside the surface of a needle, as a possible alternative to solid-phase microextraction (SPME). Thermal desorption was subsequently, employed to transfer the extracted analytes into the injection port of a gas chromatography-mass spectrometry (GC-MS). The PPy sorbent including polypyrrole-dodecyl sulfate (PPy-DS) was deposited on the interior surface of a stainless steel needle from the corresponding aqueous electrolyte by applying a constant deposition potential. The homogeneity and the porous surface structure of the coating were examined using the... 

    Using self organizing map to infer communities in weblogs' social network

    , Article 2007 IADIS European Conference on Data Mining, DM 2007, part of the 1st IADIS Multi Conference on Computer Science and Information Systems, MCCSIS 2007, 3 July 2007 through 8 July 2007 ; 2020 , Pages 58-64 Jamali, M ; Abolhassani, H ; Khalilian, M ; Sharif University of Technology
    IADIS Press  2020
    Abstract
    Nowadays users of the Web are encouraged to generate content on the Web by themselves. Weblogs are the most popular tools to do this. In fact Weblogs are one kind of social networks and they are one of the most important components in Web 2.0. Blogs are often situated within a Blog community of similar interest. These communities can be a useful way for readers to access space slice of millions of Weblogs. In this paper we introduce a new algorithm to infer communities based on their link structure. This algorithm uses self organizing maps to identify communities among Weblogs. The link pattern of each Weblog is the input for SOM. © 2007 IADIS  

    Investigation of the performance of modified organic Rankine cycles (ORCs) and modified trilateral flash cycles (TFCs) assisted by a solar pond

    , Article Solar Energy ; Volume 182 , 2019 , Pages 361-381 ; 0038092X (ISSN) Zeynali, A ; Akbari, A ; Khalilian, M ; Sharif University of Technology
    Elsevier Ltd  2019
    Abstract
    Solar pond is a type of solar collector that stores solar energy in the form of heat. The solar pond can be used as a low-temperature heat source for electricity generation. In this paper, to find the most suitable power cycle for power generation from the solar pond, the performance of the Organic Rankine Cycle (ORC), Trilateral Flash Cycle (TFC) and their modified forms with an open feed liquid heater and an internal heat exchanger for different working fluids was investigated. Water was considered as the heat transfer fluid which transfers the stored heat from the solar pond to the working fluid of the cycle. The results indicate that in all cases, the energy and exergy efficiency of the... 

    A novel sol-gel-based amino-functionalized fiber for headspace solid-phase microextraction of phenol and chlorophenols from environmental samples

    , Article Analytica Chimica Acta ; Volume 616, Issue 1 , 2008 , Pages 49-55 ; 00032670 (ISSN) Bagheri, H ; Babanezhad, E ; Khalilian, F ; Sharif University of Technology
    2008
    Abstract
    A novel amino-functionalized polymer was synthesized using 3-(trimethoxysilyl) propyl amine (TMSPA) as precursor and hydroxy-terminated polydimethylsiloxane (OH-PDMS) by sol-gel technology and coated on fused-silica fiber. The synthesis was designed in a way to impart polar moiety into the coating network. The scanning electron microscopy (SEM) images of this new coating showed the homogeneity and the porous surface structure of the film. The efficiency of new coating was investigated for headspace solid-phase microextraction (SPME) of some environmentally important chlorophenols from aqueous samples followed by gas chromatography-mass spectrometry (GC-MS) analysis. Effect of different... 

    Histogram based reflection detection

    , Article 2011 7th Iranian Conference on Machine Vision and Image Processing, MVIP 2011 - Proceedings, 16 November 2011 through 17 November 2011 ; November , 2011 , Page(s): 1 - 5 ; 978-1457715334 ; 9781457715358 (ISBN) Ahmadi, A ; Ahani, S ; Khalilian, H ; Gholampour, I ; Sharif University of Technology
    2011
    Abstract
    Reflection appears as a layer that partly covers the original image. This phenomenon may cause failure in extracting information from images of reflecting objects. This work presents an automated technique for determining of reflection area as well as its severity to define reliability of extracted information. This is done by analyzing histogram and objects found in the image. We present a strong detector based on combining the results of these two procedures. We presented new reflection detection algorithm and a new method to find a good threshold value for converting any image into a binary image. The average reflection detection accuracy of the proposed algorithm is more than 95% for... 

    Pinch Analysis of Heat Exchanger Networks in the Crude Oil Distillation Unit of Bandar-Abbas Refinery

    , M.Sc. Thesis Sharif University of Technology Hesabi, Ashkan (Author) ; Sadrhosseini, Hanieh (Supervisor) ; Shafii, Mohammad Behshad (Supervisor)
    Abstract
    Since oil prices continue to increase, energy conservation remains the prime industrial concern. Existing processes in power plants and oil refineries are not energy efficient as they should be therefore new projects can be defined to increase the energy efficiency without incurring any cost. The most appropriate utility for the processes should be explored to reduce emissions, increase the plant capacities and improve product qualities and energy efficiencies by one coherent strategic plan for the overall site which can be achieved by a full understanding of pinch technology and awareness of the available tools for applying it in practical way. Since the distillation unit of crude oil... 

    The Optimization of Self-Assembled Coacervate Drug Delivery Systems to Enhance Uptake by Macrophages and Their Polarization Towards an Anti-Inflammatory Phenotype

    , M.Sc. Thesis Sharif University of Technology Delzendeh Rooy, Alireza (Author) ; Safari, Hanieh (Supervisor) ; Mashayekhan, Shohreh (Supervisor)
    Abstract
    Macrophages play a crucial role in the healing process of chronic wounds in diabetic patients. These cells polarize from a pro-inflammatory M1 phenotype to an anti-inflammatory M2 phenotype, guiding the initial inflammation toward tissue repair and regeneration. In diabetic patients, physiological disturbances impair this polarization, resulting in persistent, chronic, and inflamed wounds. Glucocorticoid anti-inflammatory drugs are commonly used but have serious side effects, necessitating targeted delivery systems. This study aims to design and optimize self-assembled complex coacervate drug delivery system composed of gelatin and sodium alginate (GA/SA CCA) that can selectively uptake by... 

    Determination of fentanyl in human plasma by head-space solid-phase microextraction and gas chromatography-mass spectrometry

    , Article Journal of Pharmaceutical and Biomedical Analysis ; Volume 43, Issue 5 , 2007 , Pages 1763-1768 ; 07317085 (ISSN) Bagheri, H ; Es-haghi, A ; Khalilian, F ; Rouini, M. R ; Sharif University of Technology
    2007
    Abstract
    A head-space solid-phase microextraction (HS-SPME) method coupled to GC-MS was developed to extract fentanyl from human plasma. The protein binding was reduced by acidification and, eventually, the sample was deproteinized with trichloroacetic acid. The parameters influencing adsorption (extraction time, temperature, pH and salt addition) and desorption (desorption time and temperature) of the analyte on the fibre were investigated and validated for method development. The developed method proved to be rapid, simple, easy and inexpensive and offers high sensitivity and reproducibility. Linear range was obtained from 0.1 ng/ml to 2 μg/ml. The limit of detection was 0.03 ng/ml while an... 

    Digital video watermarking in 3-D ridgelet domain

    , Article 11th International Conference on Advanced Communication Technology, ICACT 2009, Phoenix Park, 15 February 2009 through 18 February 2009 ; Volume 3 , 2009 , Pages 1643-1646 ; 17389445 (ISSN); 9788955191387 (ISBN) Khalilian, H ; Ghaemmaghami, S ; Omidyeganeh, M ; IEEE Communications Society, IEEE ComSoc ; Sharif University of Technology
    2009
    Abstract
    A new method for digital video watermarking is presented in this paper. For data embedding we use 3-D ridgelet domain introduced by Helbert. The redundancy of this transform is substantial, so extraction of the hidden data is impossible in this domain. To overcome this problem, we introduce a modified ridgelet transform with little redundancy, and embed watermark in this domain. Experimental results show that this scheme is robust against collusion attack, frame cropping, frame swapping, frame dropping, noise attack and the MJPEG (Motion JPEG) compression  

    Synthesis of Graphene Quantum Dots for Biomedical Application

    , M.Sc. Thesis Sharif University of Technology TaghaviLarijani, Hanieh Sadat (Author) ; Sadrnezhaad, KHatiboleslam (Supervisor) ; Ahhadiaan, Mohammad Mehdi (Co-Advisor)
    Abstract
    Graphene quantum dots (GQDs) as a sort of carbon-based nanomaterials are applied in a multitude of exciting areas. They are effective fluorescent probe for many potential biological and medical applications. In comparison to conventional organic fluorescent probes (organic dyes), GQDs have substantial advantages, such as photostability, excellent solubility, low cytotoxicity and biocompatibility.
    In this thesis, green fluorescent GQDs have been prepared via solvothermal method from graphite powder.Various analysis methods were utilized to characterization of the product. So, several experiments on GQDs in solution and in solid substrate at room temperature have been performed. The...