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khanmohammadi--mehdi
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Design, Fabrication and Evaluation of Polymeric Microcapsules Containing Cells to Use in Cell Therapy in Heart
, M.Sc. Thesis Sharif University of Technology ; Mashayekhan, Shohreh (Supervisor) ; Sharifi, Ali Mohammad (Supervisor) ; Khanmohammadi, Mehdi (Co-Supervisor)
Abstract
Because of the inability of conventional methods to regenerate the infarcted part of the heart, regenerative medicine based on using scaffolds and hydrogels incorporation with cells and biological factors emerges as a promising approach. Micro-structures, especially hollow microcapsules created by the microfluidic system, has received a great deal of attention due to their inspired biomimetic structures, providing complete coverage cells, and preventing an immune response, consequently. This study aimed to use a microfluidic system to fabricate hollow microcapsules and investigate the behavior of rat cardiomyoblast cells (H9C2) along with exosomes within these structures. These structures'...
A Framework to Evaluate the Resilience of Hospitals
, M.Sc. Thesis Sharif University of Technology ; Kashani, Hamed (Supervisor)
Abstract
In the aftermath of earthquakes, hospitals serve the critical role of treating casualties and reducing mortalities and severe injuries. A hospital must be resilient to play its role correctly after the earthquake. A resilient hospital is able to maintain its functionality at an acceptable level and provide service to the injured. In order to enhance the resilience of a hospital, an appropriate framework is needed to evaluate the hospital resilience and determines the impact of modification actions. This framework should characterize the serviceability of a hospital in terms of an appropriate metric. In this framework, the behavior of a given hospital building in the event of an earthquake as...
Fuzzy hierarchical location-allocation models for congested systems [electronic resource]
, Article Scientia Iranica ; January 2006, Scientia Iranica, Vol. 13, No. 1, pp. 14-24 Journal of Industrial and Systems Engineering ; 2007, Vol. 1 No. 2, pp 171-189 ; Mahlouji, Hashem ; Eshghi, Kourosh ; Khanmohammadi, S ; Sharif Universitty Of Technology
Abstract
There exist various service systems that have hierarchical structure. In hierarchical service networks, facilities at different levels provide different types of services. For example, in health care systems, general centers provide low-level services such as primary health care services, while the specialized hospitals provide high-level services. Because of demand congestion in service networks, location of servers and allocation of demand nodes have a strong impact on the length of queues at servers as well as on the response times to service calls. The thrust of this article is the development of hierarchical location-allocation models for congested systems by employing queueing theory...
A system dynamics approach to the seismic resilience enhancement of hospitals
, Article International Journal of Disaster Risk Reduction ; Volume 31 , 2018 , Pages 220-233 ; 22124209 (ISSN) ; Farahmand, H ; Kashani, H ; Sharif University of Technology
Elsevier Ltd
2018
Abstract
In the aftermath of earthquakes, hospitals serve the critical role of treating casualties. In many cases, the key components of a hospital (i.e., the building, staff, medicine inventory, technical systems, and medical equipment) are affected by an earthquake. To handle the demand surge, affected hospitals should recover in an effective manner. Hospital recovery is a complex and dynamic process because each component requires specific types and amount of resources to recover. Furthermore, the recovery of each component not only affects its performance but also plays a role in the overall hospital recovery. Hospital administrators need to model the complex recovery process after a future...
A cellular cardiac matrix-based porous microcarrier as a cell delivery system in myocardial tissue engineering application
, Article Iranian Polymer Journal (English Edition) ; Volume 31, Issue 9 , 2022 , Pages 1079-1091 ; 10261265 (ISSN) ; Mashayekhan, S ; Khanmohammadi, M ; Sharif University of Technology
Springer Science and Business Media Deutschland GmbH
2022
Abstract
Myocardial infarction (MI) causes a high mortality rate in the world every year. Myocardial tissue engineering using extracellular matrix-derived substrate and cytocompatible biopolymers is a promising approach for treating MI. Besides, injectable porous microspheres are developing engineer constructs to use as dual-purpose microcarriers for cell culture and injectable scaffolds in trivial invasiveness for tissue implantation. This study aimed to fabricate porous microcarriers composed of myocardial extracellular matrix and chitosan using an electrospraying technique. The effect of electrospraying parameters, including extracellular matrix/chitosan ratio and voltage, on MCs diameter was...
On the existence of nowhere-zero vectors for linear transformations
, Article Bulletin of the Australian Mathematical Society ; 2010 , Pages 1-8 ; 00049727 (ISSN) ; Hassani Monfared, K ; Jamaali, M ; Khanmohammadi, E ; Kiani, D ; Sharif University of Technology
2010
Abstract
A matrix A over a field F is said to be an AJT matrix if there exists a vector x over F such that both x and Ax have no zero component. The Alon-Jaeger-Tarsi (AJT) conjecture states that if F is a finite field, with |F|≥4, and A is an element of GL n (F), then A is an AJT matrix. In this paper we prove that every nonzero matrix over a field F, with |F|≥3, is similar to an AJT matrix. Let AJTn (q) denote the set of n×n, invertible, AJT matrices over a field with q elements. It is shown that the following are equivalent for q≥3 : (i) AJTn (q)=GL n (q) ; (ii) every 2n×n matrix of the form (A{divides}B)t has a nowhere-zero vector in its image, where A,B are n×n, invertible, upper and lower...
Design and Fabrication of Inductive High Temperature Superconducting Fault Current Limiter
,
Ph.D. Dissertation
Sharif University of Technology
;
Vakilian, Mehdi
(Supervisor)
;
Fardmanesh, Mehdi
(Supervisor)
Abstract
The continuous rise in electricity demand and the ever growing power generation in different power networks over the world have caused the short circuit level in the power systems to exceed the operational rating of the installed power devices (including cables, circuit breakers and buses). Replacing these devices with new higher rating devices is an expensive solution. From this point of view, utilizing fault current limiters is an economical solution. Superconducting fault current limiters form an efficient category of current limiters. This type is expected to be studied and used widely in future due to their advantages. In this thesis, the first chapter reviews the superconductivity...
Enhancement of THz Radiation from Josephson Junctions in Superconductors Using Electromagnetic Resonators
,
M.Sc. Thesis
Sharif University of Technology
;
Ahmadi Boroujeni, Mehdi
(Supervisor)
;
Fardmanesh, Mehdi
(Supervisor)
Abstract
Terahertz waves which includes frequencies between 100 GHz to 10 THz of electromagnetic spectrum have found many applications in science, medical treatments and industry. One of the recent methods to produce these waves is using nonlinear properties of superconductors based on Josephson junctions which inherently appear in some superconductors called BSCCO. Stack of intrinsic junctions of these superconducting materials can radiate terahertz waves by only applying a DC voltage across them. This Thesis investigates some of these structures based on Josephson junctions to produce coherent radiation of terahertz waves. For the optimization of the radiation power, this study also investigates...
Production of uniform size cell-enclosing silk derivative vehicles through coaxial microfluidic device and horseradish crosslinking reaction
, Article European Polymer Journal ; Volume 172 , 2022 ; 00143057 (ISSN) ; Hosseini, M ; Varaa, N ; Mahmoodi, N ; Goodarzi, A ; Taghdiri Nooshabadi, V ; Hassanzadeh, S ; Arabpour, Z ; Khanmohammadi, M ; Sharif University of Technology
Elsevier Ltd
2022
Abstract
Silk fibroin (SF) as a natural biopolymer holds great potential in biomedical research because of its biocompatibility, easy processability and high strength properties. However, slow gelation time has narrowed its applications, specifically in cell-laden microparticle production due to insufficient crosslinkable moieties. This study aimed to develop cell-laden silk fibroin-phenol (SF-Ph) microparticle through co-flow microfluidic system using SF conjugated Ph moieties whereas covalent crosslinking is mediated with horseradish peroxidase (HRP) in the presence of hydrogen peroxide (H2O2). For this, the SF-Ph was synthesized through carbodiimide condensation crosslinking reaction. Aqueous...
On the Spectrum of Modified Theories of Gravity
, M.Sc. Thesis Sharif University of Technology ; Golshani, Mehdi (Supervisor) ; Sheikh Jabbari, Mohammad Mehdi (Supervisor)
Abstract
There are different approaches in modifications of General Relativity as the theory of gravity. The modified theories of gravity are important cases in this context, which mostly start by modifying the Einstein-Hilbert action, while keeping the general covariance. Within the modified theories of gravity, we consider two cases. The first is the f(R) theories of gravity, and the second is curvature squared theories of gravity with an action like S = ∫d4x pg( 116GR + (R)2 + R2 +(R)2). Curvature squared theories of gravity have interesting feautures, most important of which is renormalizability, in contrast with General Relativity. But this advantage, as noted by K.S. Stelle in 1977 comes at...
On Thermodynamics and Phase Space of Near Horizon Extremal Geometries
, Ph.D. Dissertation Sharif University of Technology ; Sheikh-Jabbari, Mohammad Mehdi (Supervisor) ; Golshani, Mehdi (Co-Advisor)
Abstract
Near Horizon Extremal Geometries (NHEG), are geometries which may appear in the near horizon region of the extremal black holes. These geometries have SL(2;R)U(1)n isometry, and constitute a family of solutions to the theory under consideration. In the first part of this report,their thermodynamic properties are reviewed, and their three universal laws are derived. In addition, at the end of the first part, the role of these laws in black hole thermodynamics is presented. In the second part of this thesis, we review building their classical phase space in the Einstein-Hilbert theory. The elements in the NHEG phase space manifold are built by appropriately chosen coordinate transformations of...
Critique and Survey of Various Formulation of Multiverse Theory
, Ph.D. Dissertation Sharif University of Technology ; Golshani, Mehdi (Supervisor) ; Sheikh Jabbari, Mohammad Mehdi (Supervisor)
Abstract
Multiverse scenario has been recently addressed by physicists and they have found it useful in many areas of physics. In this dissertation, I have treated some issues about multiverse such as the kinds of multiverses, the arguments for or against multiverse, areas in which multiverse is introduced, etc. This dissertation has six chapters and an appendix. In the chapter one, some classifications of multiverse is introduced, and also some definitions of the concept of a world is presented. Then, my classification and definition of a multiverse and a world is introduced. In the chapter two, the concept of possible worlds in philosophy and its relationship with multiverse hypothesis is examined....
Optimal Multicriteria Design of HTS Transformer and Construction of a Laboratory Scale Sample
, Ph.D. Dissertation Sharif University of Technology ; Vakilian, Mehdi (Supervisor) ; Fardmanesh, Mehdi (Co-Supervisor) ; Hekmati, Arsalan (Co-Supervisor)
Abstract
Employing high-temperature superconducting (HTS) tapes, instead of copper or aluminum wires for winding in a superconducting transformer, results in a series of significant advantages; such as: smaller volume, lighter weight, higher efficieny, greatly extended overload capability, better voltage regulation, lower life cycle cost, fault current limiting capability, lower environmental pollution and lower risk potential against fire hazards.In this thesis, optimal design of flux diverter using genetic algorithm for axial short circuit force reduction in HTS transformers has been performed. Then, multilayered flux diverters have been proposed for reduction of weight and losses. The impact of...
A Multi-Objective Robust Optimization Model for Logistics Planning in the Earthquake Response Phase [electronic resource]
, Article Transportation Research Part E: Logistics and Transportation Review, Elsevier ; Volume 49, Issue 1, January 2013, , Pages 217–249 ; Eshghi, Kourosh ; Dullaert, Wout ; Sharif University of Technology
Abstract
Usually, resources are short in supply when earthquakes occur. In such emergency situations, disaster relief organizations must use these scarce resources efficiently to achieve the best possible emergency relief. This paper therefore proposes a multi-objective, multi-mode, multi-commodity, and multi-period stochastic model to manage the logistics of both commodities and injured people in the earthquake response. Also, a robust approach is developed and used to make sure that the distribution plan performs well under the various situations that can follow an earthquake. Afterwards, it proposes a solution methodology according to hierarchical objective functions and uses it to illustrate the...
Monitoring of Valve Leakage in Internal Combustion Engine Using Acoustic Emission Method
, Ph.D. Dissertation Sharif University of Technology ; Behzad, Mehdi (Supervisor) ; Mehdigholi, Hamid (Supervisor) ; Ahmadi, Mohammad Mehdi (Co-Advisor)
Abstract
Valve leak detection is very important due to bad direct effects on parts life and engine power. Acoustic emission (AE) has a good known ability on leak detection between fault detection methods. The aim of this thesis is presenting the ability of AE method for valve leak detection in internal combustion engines. The research method in a general framework based on the idea that firstly some evaluations were done in static tests for leakage due to three faults including clearance, quasi-crack and notch. Then, the evaluations were continued with dynamic analysis of rotational speeds and different loads on the engine. Finally, the neural network approach was used to automatically detect all...
Evaluation of Electromagnetic Forces on three-phase Core-Type Power Transformer Windings during Inrush Current by FEM
, M.Sc. Thesis Sharif University of Technology ; Vakilian, Mehdi (Supervisor)
Abstract
Inrush Current is a form of over-current that occurs during energization of a transformer. For power transformers, the magnitude of the first peak of inrush current is initially several times the rated load current but slowly decreases until it finally reaches the normal exciting current value. This process typically takes several minutes. Time-variant axial and radial electromagnetic forces under inrush current and short-circuit current are calculated (by finite element method; FEM), and compared. An analytic method is presented for computation of inrush current in transformer. The simulation results obtained by this proposed method are compared with the measured values. A compact...
Relative Merits of the Two Famous Formulations of Bohmian Mechanics
, Ph.D. Dissertation Sharif University of Technology ; Golshani, Mehdi (Supervisor)
Abstract
The goal of this thesis is to evaluate the strengths and weaknesses of the two existing formulations of Bohmian mechanics. The first one was proposed by Bohm, and emphasizes on the dynamics being second-order, and in which, the key tool for explaining the quantum phenomena is a non-classical potential, called "the quantum potential". In this approach, the postulates of de Broglie's "pilot-wave" theory, which now is known as Bohmian mechanics, are non-fundamental and are special to the atomic level. The possibility is proposed that these postulates become subjected to some modifications at the nuclear or lower levels, but no particular way for performing such modifications is suggested. The...
Ground Water Denitrification by Packed Bed Bioreactor With KMT Packing
, M.Sc. Thesis Sharif University of Technology ; Borghei, Mehdi (Supervisor)
Abstract
In this study biological denitrification method by moving bed biofilm reactor is investigated. The main advantage of MBBR reactor is due to their capacity for high removal rates and low operational problems such as clogging. Two MBBRs in series with 3 liter volume each, were designed in experimental set up and used in this research. Nitrification reactor worked under aerobic conditions and denitrification reactor operated under anaerobic conditions. Methanol was used as carbon source in the reactors throughout the study. Fifty percent of each reactor volume was occupied with KMT1 packing. To finding the optimum nitrate loading rate, the concentration of ammonium and nitrate were changed from...
Genco's Bidding Strategy in Day-Ahead Energy Market Considering Demand Response
, M.Sc. Thesis Sharif University of Technology ; Ehsan, Mehdi (Supervisor)
Abstract
Since 1980s the electricity market has been gradually evolving from a monopoly market into a liberalized one for encouraging competition and improving efficiency. This brings the opportunity for generation companies (Gencos) to make more profits while embracing more risks of not being dispatched. Therefore, it has become a core interest for the Gencos to develop optimal bidding strategies to maximize the profits and minimize the risks while participating in such a competitive market. Error of determining day-ahead electricity price is one of the sources of the risk. Energy price has a high impact on bidding strategy optimization process. So it should be determined with low error which is not...