Sharif Digital Repository

Cell lysis, as the first procedure of cell pretreatment, is a process that breaks cell membranes open thereby facilitating access to intracellular substances, such as DNA, proteins, and other components for further analysis to diagnose and treat diseases at early stages. Currently, there are several methods for cell lysis at macroscales. However, the time-consuming and expensive procedures as well as the large scal of the system are the main disadvantages of the systems. Recently, microfluidic systems have attracted considerable attention due to advantages associated with automation, integration and miniaturization of biomedical test protocols. Centrifugal microfluidics (Lab-on-a-Disc) is a... 

LOOP accident is one of the most important accidents in NPPS and it leads to loss of power supply of the RCP pumps which are the main pumps of primary circuit. Subsequently trip of the rector occurs. In safety analysis, concerning worst conditions, assumes that after a small period of time, main generator of plant stops working and loss of AC power supply of all power plant loads including safety systems ocures. To control of this accident, it’s necessary to startup and load backup power supply system (EDGs) for at least one safety channels, if not, the accident moves forwards and becomes S.B.O accident which is more important accident that ends to core damage because of stops working of all... 

Nowadays the concept of competition in business has been expanded from enterprises to supply chains. For success in this competitive environment, it should be established complete coordination and synchronization between different rings of the chain in both strategy and operations. The supply chain management is a factor for achieving to this purpose. Effective supply chain management, especially in complex supply chains like petroleum upstream supply chain, requires to strategic factors that propel the chain to the long term goals. Unfortunately, it is showing off the vacancy of attending to this case in the literature. This thesis tries to fill this gap in literature with a new approach... 

Storage subsystem is one of the most important components of a computer system. As more valuable information such as bank transactions are being stored in storage subsystems,occurrence of an unrecoverable error can lead to a much bigger problem. A storage subsystem can be divided into software and hardware part. Previous works focused on fault injection in the higher layers of the storage stack and didn’t consider fault injection at the device driver level. In this thesis, the dependability of storage stack is evaluated using fault injection at the device driver layer. Various hardware and software faults that can occur in hard disks and solid state drives are studied and dependability of... 

Einstein's general theory of relativity is an admirable successful and unifier geometrical modeling among concepts of space, time and gravity. This theory along with special theory of relativity made a massive change in our physical view and this, especially in its historical context, has deep and interesting consequences in man's philosophical viewpoint which can be studied. Some parts of this thesis relates to these consequences. Some of these interesting consequences may be hidden by computional or mathematical viewpoint and often these equations do not contain enough intuition. in one part, we provide a formulizatin of Einstein's equaion that is intuitional which can be translated in... 

Tropical algebraic geometry is a fairly new branch in geometry which is called so in honor of Brazilian mathematician Imre Simon who was pioneer of this field.The set equipped with the addition and multiplication is a semifield.Algebraic geometry objects like algebraic varieties can be defined over.Polynomials and rational functions are defined over.The functions that they define are piecewise linear and concave functions and the set of points where they are nonlinear is a tropical variety which is a concave polyhedral. Thus, tropical algebraic geometry is a piecewise linear version of algebraic geometry.Another approach to tropical algebraic geometry comes back to the works of Russian... 

Fatigue cracking has a major impact on the performance of flexible pavements. Many test methods have been established to evaluate and estimate the fatigue life of asphaltic materials. Most of these test methods cannot successfully examine the fatigue properties of asphaltic materials. Recent studies demonstrate that using a standardized composite, which consists of glass beads and asphalt binder, can simulate the stress states that binder experiences in the field. This research used standardized composite to investigate the effect of crumb rubber on the fracture properties of asphaltic materials. To validate the test results, the authors conducted fracture tests on the Fine Aggregate Matrix... 

In the last two decades, novel view synthesis has become increasingly important in the movie and game industries. The new generated views correspond to virtual viewpoints, where no real camera has taken snapshot. Depending on the amount of available information from the scene, different approaches have been proposed to create novel views. If the depth information is available, then by knowing camera relative motion, novel views can be constructed. The conventional cameras only record the intensity of the captured scene, and discard the depth information. In the recent concept of light field cameras, by locating an array of micro-lenses between the camera sensor and the main lens, one can... 

Chip seal is one of the most economical pavement maintenance practice that extends pavement life. To ensure chip seal good performance several quality control methods have been developed. However, most of these methods are qualitative and only measure the stone loss under a certain number on loading. This research developed a new method for quality control of chip seal, based on the assumption that characteristics of the bond between chips and pavement surface play a key role in chip seal performance. To validate this test method, the authors used a wheel track loading test. The results from this research clearly showed that the characteristics of the bond between chips and pavement surface... 

Recently, a new method to investigate chip seal performance has developed by a research team at Sharif University of Technology. This study investigates the effect of various additives such as CRM, SBR Latex, Hydrated Lime and Ordinary Portland Cement (OPC), on the curing time of chip seal by this method. In addition, the chip seal treatments were investigated in different climate conditions like Wet and Wet-Freeze zones. The overall performance of mixture specimens evaluated using creep loading test. In fact, the bonding properties between aggregates and surface of Hot Mix Asphalt measured. The test results were analyzed by using of the work and time parameters. These parameters were...