Sharif Digital Repository

Microarray which is also known as Biochip is a flat substrate of glass with the size of 1 ×1 cm on which a numerous number of biosensors are placed in an array format. Microarray DNAs are used to measure expression level of thousands of genes. Repeating these experiments in different conditions can result in patterns of expression. After preparation, the florescent sample is hybridized with the sensors of microarray surface and fluoresce intensities of the spots are measured by a special camera called CCD. The obtained pictures are examined by a computer and the spot lights converted into numerical data by image processing algorithms. Putting these numbers into matrices of size m×n is... 

Thermal energy and water in flue gases varies with the type of fuel and thermal conversion system. Flue gas temperature is maintained in the range of 140 (℃) to 200 (℃) and it is subject to the sulfur content of the fuel. Vapor content of the flue gas is in the range of 10%_20% of volumetric flow. Considerable part of vapor may be recovered which can be used as cooling water make up. There are various means and methods for water capture and heat recovery which includes shell-tube heat exchanger among others. Selection of appropriate material and heat exchanger is conditioned by corrosion, temperature of flue gas and it’s economic feasibility. Identification of an optimal design of... 

The goal of this research is design and manufacturing of a device for fatigue test and 3D crack propagation in spur gear roots. Clearly it should be able to test gear in oscillated bending load and control the amplitude and period of loading. Designed setup in this project using a electro hydraulic actuator can do it up to 50 KN and 10 Hz in amplitude and frequency and a PLC controls it during the test time. System can load gears symmetric or anti symmetric and simulate the effect of shaft misalignments, bearing damage and gear production tolerances on the gear loading. System completely designed, built and tested during this project and using experimental data, its performance was... 

Traditional classification techniques of machine learning assume that data have stationary distributions. This assumption for recent challenges where tremendous amount of data are generated at unprecedented rates with evolving patterns, is not true anymore. Classification of data streams has become an important area of machine learning, as the number of applications facing these challenges increases. Examples of such data streams applications include text streams, surveillance video streams, credit card fraud detection, market basket analysis, information filtering, computer security, etc. An appropriate method for such problems should adapt to drifting concepts by revising and refining the... 

Isn’t our universe ,which includes everything that is causally connected to us, a tiny and negligible part of wider and diverse “multiple universes”? Although the multiverse idea has been considered by scientists recently, it had been discussed by philosophers and theologians in the past.
Many of our physical theories,whether being accepted like General Relativity, or speculative like string theory, lead naturally to the multiverse idea .The idea of multiverse is also brought forth to take care of the fine tuning observed in cosmology, in connection with the so – called anthropic principle.
This idea appeared in order to answer to some problems of quantum mechanics, string theory... 

Duplex stainless steels and advanced high strength steels are both known as new materials in automobile industry applications. Process of resistance spot welding is the main process in welding of auto-body structures. Hence investigating the welding metallurgy and weldability of similar and dissimilar joints of duplex stainless steels and advanced high strength steel are crucial. The purpose of this study is to analyse the relationship between welding process and geometric characteristic of weld nugget, phase transformations of Weld nugget and heat affected zone, mechanical properties (i.e force bearing capacity and energy absorption capability) and failure mode (interfatial or pullout). in... 

Mixed-criticality embedded systems, as the next-generation of safety-critical systems, are increasingly employed in industry due to consolidating functionalities with varying criticality levels onto the same computing platform. Also, cost reduction and performance improvement encourage adoption of multicore platforms in these systems. Technology scaling, battery-supplied design and heavy computation in mixed-criticality systems necessitates employing energy management techniques. Due to the degrading effects of these techniques on the system’s reliability, reducing energy consumption without sacrificing the reliability requirement is a vital challenge in mixed-criticality systems, in... 

Passive wideband reconnaissance receivers, listen to the radio and radar signals in the environment and estimate their important parameters such as direction of arrival (DOA). The wideband attribute for these receivers is to refer to their ability to receive wideband signals.Due to the use of processing gain, LPI radars reduce their transmitted signal power to see and not to be seen. On the other hand reconnaissance receivers can not have much processing gain, because they do not know the nature of the transmitted signal; Therefore, to increase the operational range of these systems, it is necessary to increase the signal to noise power ratio (SNR). This thesis examines the use of antenna... 

We have reported a new and efficient synthesis of tetrahydrothiopyrano [2,3-b]indole skeletons via unique tandem reaction of indoline-2-thiones to Baylis-Hillman adduct acetates. This protocol is a very mild and simple method for construction heterocycles in a one-step process. This is a convenient and diastereoselective synthesis of methyl 4-aryl-2,3,4,9-tetrahydrothiopyrano[2,3-b]indole-3-carboxylate systems in the presence of K2CO3 in acetonitrile. The major benefits of the current study are the one-pot procedure, high yields and diastereoselectivity, short reaction times and the similarity of the products to the biologically active moieties.
In addition 1, 4-diazabicyclo [2.2.2]... 

About a century, “Eye Tracking” has been studied, and it has two definitions: • The process of measuring the point of gaze (where one is looking). • The process of measuring the motion of an eye relative to the head. Eye tracking technology has been used in many fields such as psychology. However, applications of this technology has been recently considered in marketing, computer interfacing, entertainment, training and so forth. Since pupil is a distinc area in eye images, pupil detection is one of the effective solutions of eye tracking. In most of the pupil detection approaches, the edge points of the pupil contour are detected firstly, and then the optimal ellipse is fitted to them....