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    Emerging bioengineering strategies for regulating stem cell fate: Scaffold physical and biochemical cues

    , Article Tissue Engineering: Current Status and Challenges ; 2022 , Pages 125-156 ; 9780128240649 (ISBN) Sharareh Mahdavi, S ; Mashayekhan, S ; Sharif University of Technology
    Elsevier  2022
    Abstract
    Stem cell therapy has been introduced as an emerging approach for injured tissue regeneration. This chapter addresses developing regenerative medicine techniques for controlling stem cell behavior. Recent studies have been reviewed and novel approaches have been divided into four main categories: 3D bioprinting, lithography, microfluidics, and electrospinning. Moreover, the impact of applied biophysical and/or biochemical cues to the designed scaffold on controlling stem cell activity has been discussed. The potential of using stem cells for various soft and hard tissue regenerations has been explored in different bioengineered scaffolds and the applied techniques for controlling stem cell... 

    Simulation of the Urinary Concentration Mechanism

    , M.Sc. Thesis Sharif University of Technology Mahdavi Salimi, Sharareh (Author) ; Abd Khodaei, Mohammad Jafar (Supervisor) ; Farhadi, Fathollah (Supervisor)
    Abstract
    The kidneys serve essential regulatory roles in the body which remove excess organic molecules from the blood and the removal of waste products of metabolism. They are essential in the urinary system. Urinary concentration mechanism has long been interested for mathematicians and physiologists to elucidate the obscurities within the process. In this study, a novel three-dimensional approach is used for simulating urine concentrating mechanism in rat renal medulla. The model equations are based on three spatial dimensions mass and momentum transports. Exact 3D geometry has been designed by using COMSOL Multiphysics software and results have been compared with the latest available data. In... 

    A Study on the Shannon Zero Error Capacity of Graphs

    , M.Sc. Thesis Sharif University of Technology Izadi Moein, Ali (Author) ; Jafari, Amir (Supervisor) ; Alipour, Sharareh (Supervisor)
    Abstract
    The issue of reliability, which is associated with a low probability of error in a communication system, is an important parameter in information theory. By reliability, we mean a low decoding error probability, and one of the main criteria for this is the zero decoding error probability. In the zero-error probability, the decoding error probability for any code is exactly zero. Error-free capacity was examined by Claude Shannon in 1956. The Shannon capacity of a communication channel is defined using the independent sets of strong products of graph. Shannon calculated the capacity of graphs up to five vertices except the graphC5. Lovász, in 1979, using the upper bound he provided, was able... 

    Scaffold Fabrication for Corneal Regeneration

    , Ph.D. Dissertation Sharif University of Technology Mahdavi Salimi, Sharareh (Author) ; Abdekhodaie, Mohammad Jafar (Supervisor) ; Mashayekhan, Shohreh (Supervisor) ; Baradaran Rafiei, Alireza (Co-Supervisor)
    Abstract
    3D bioprinting technology is a promising approach for corneal stromal tissue regeneration. At first, two different concentrations of GelMA macromer (7.5% and 12.5%) were tested for corneal stroma bioprinting. Due to high macromer concentrations, 12.5% GelMA was stiffer than 7.5% GelMA, which made it easier to handle. In terms of water content and optical transmittance of the bioprinted scaffolds, we observed that scaffold with 12.5% GelMA concentration was closer to the native corneal stroma tissue. Subsequently, cell proliferation, gene and protein expression of human corneal stromal cells encapsulated in the bioprinted scaffolds were investigated. Cytocompatibility in 12.5% GelMA scaffolds... 

    Incorporating Degree of Belief, Desire and Capability into Propositional Belief Desire and Intention Logic

    , M.Sc. Thesis Sharif University of Technology Salimi, Babak (Author) ; Ardeshir, Mohammad (Supervisor)
    Abstract
    Nowadays, BDI architecture is of the most well known agent’s architectures. BDI architecture or the architecture in which the system is viewed as rational agents based on the attitudes of belief, desire and intention represents an abstraction of human deliberation based on a theory of rational action in the human cognition process. BDI logic introduced by Rao and Georgeff have been widely used as the theoretical basis of specification and implementation of rational agents. BDI logic is limited to deal with crisp assertion, while the assertions encountered in real world are not precise and thus cannot be treated simply by using yes or no. Moreover, In order to obtain more human like agents we... 

    Synthesis of Novel Biodegradable Collagen-Based Superabsorbent Hydrogels and Investigation of their Swelling Behavior in Various Media

    , Ph.D. Dissertation Sharif University of Technology Salimi,Hamid (Author) ; Pourjavadi, Ali (Supervisor)
    Abstract
    The use of super-swelling polymers is steadily increasing and the applications in industry are continuing to grow. With the authorization of the superabsorbents in food packaging by the Food and Drug Administration recently, demand may soon take off in the market. The worldwide production of SAPs is more than one million tons per year, representing a multibillion-dollar market. However, the increase in prices of petroleum products in recent years may be a drawback for these acrylic-based materials. Thus, there is now a need to develop natural-based super-swelling hydrogels which are more economical and environment friendly. In addition, the super-swelling gels are promising novel functions... 

    Activity-based Travel Demand Modeling in Rural Areas; Case Study of Villages Far-from-city in Fars Province

    , M.Sc. Thesis Sharif University of Technology Salimi, Farzam (Author) ; Vaziri, Manouchehr (Supervisor)
    Abstract
    Although rural inhabitants constitute a large portion of developing countries’ population, they have always been neglected in many ways. Expansion of equity, calls for a new concern in adequacy of rural development. The problem could be considered in two aspects: Firstly, there is a great tendency for immigration to nearby cities, hoping for a better life. This would result in more crowded cities, extended poverty and an increasing rate of crime mainly in suburban areas. On the other hand, the evacuation of farms and fertilized lands imposes great economical loss to the country. Therefore, development of rural facilities should be integrated into national policies to assure a homogeneous and... 

    Development of Airport Capacity Management Model Based on Decision Support System

    , M.Sc. Thesis Sharif University of Technology Salimi, Mohammad (Author) ; Pourtakdoust, Hossein (Supervisor)
    Abstract
    Airports are one of the most important elements of the aviation system that provide the ground infrastructure that is required for enabling or flight across the globe. Master Planning is currently the dominant approach to airport strategic planning. However, history shows that this approach can often result in costly mistakes. Because there are many stakeholders with conflicting objectives, deep uncertainty about the future, and many potential strategies, planners often narrow their scope by using a single forecast for the future, leaving out alternative strategies, and excluding stakeholders, resulting in a Master Plan that quickly becomes obsolete and may be opposed by some stakeholders.... 

    VulSlicer: Vulnerability detection through code slicing

    , Article Journal of Systems and Software ; Volume 193 , 2022 ; 01641212 (ISSN) Salimi, S ; Kharrazi, M ; Sharif University of Technology
    Elsevier Inc  2022
    Abstract
    There has been a multitude of techniques proposed for identifying vulnerabilities in software. Forcing a program into a vulnerable state has become increasingly unscalable, given the size of the programs and the number of possible execution states. At the same time, techniques that are looking for vulnerability signatures are marred with weak and incomplete signatures. This is not to say that such techniques have failed to identify previously unknown vulnerabilities in the code. However, they have inherent weaknesses, which result in identifying vulnerabilities that are limited in type and complexity. We propose a novel technique to extract succinct vulnerability-relevant statements... 

    Vulnerability Extraction in Large Codebases Through Template Generalization

    , Ph.D. Dissertation Sharif University of Technology Salimi, Solmaz (Author) ; Kharrazi, Mehdi (Supervisor)
    Abstract
    As the size and complexity of software increase, the number of software vulnerabilities also increases. An examination of vulnerability reports shows that in addition to the fact that a large number of unknown vulnerabilities still exist in software, there is still no proper solution for identifying vulnerabilities that have been observed one sample of them exit in real-world software. The main reason for such an event is the lack of a suitable template for recognized vulnerabilities, which ultimately makes searching for them in other software a problem of scalability and high search cost. This thesis, recognizing the importance of the issue, presents a framework for extracting robust and... 

    The olfactory bulb modulates entorhinal cortex oscillations during spatial working memory

    , Article Journal of Physiological Sciences ; Volume 71, Issue 1 , 2021 ; 18806546 (ISSN) Salimi, M ; Tabasi, F ; Nazari, M ; Ghazvineh, S ; Salimi, A ; Jamaati, H ; Raoufy, M. R ; Sharif University of Technology
    BioMed Central Ltd  2021
    Abstract
    Cognitive functions such as working memory require integrated activity among different brain regions. Notably, entorhinal cortex (EC) activity is associated with the successful working memory task. Olfactory bulb (OB) oscillations are known as rhythms that modulate rhythmic activity in widespread brain regions during cognitive tasks. Since the OB is structurally connected to the EC, we hypothesized that OB could modulate EC activity during working memory performance. Herein, we explored OB–EC functional connectivity during spatial working memory performance by simultaneous recording local field potentials when rats performed a Y-maze task. Our results showed that the coherence of delta,... 

    PMU Based Fault Location on Transmission Lines

    , M.Sc. Thesis Sharif University of Technology Salimi, Saeed (Author) ; Ranjbar, Alimohammad (Supervisor)
    Abstract
    One of the most essential part of power system are transmission lines. Transmission of power from production centers to consumption centers is duty of these lines. Any disturbance in this duty make great losses to producers and consumers. One of the most disturbance in transmission lines are short circuits that occurred because of various causes. Most faults on transmission lines occurred in stormy weather that make more troubles for fault search. So we need a tool that can find location of fault precisely and quickly. This tool named fault locator. There are many algorithms for fault location and detection on power system transmission lines. These algorithms usually are dependent on very... 

    Hazard Identification by HAZOP Method and Risk Assessment Based on Fuzzy Logic with Case Study

    , M.Sc. Thesis Sharif University of Technology Salimi, Ruhollah (Author) ; Rashtchian, Davood (Supervisor)
    Abstract
    According to privileged risks existing in process industries and intensity of their consequences, Safety investigation and risk assessment are highly significant in these unites. Execution of risk assessment in process unites has been constituted from two qualitative and quantitative parts. The most crucial issue in risk assessment procedure is uncertainties related to data and needed information, besides of various models presented. This subject frequently relates to deficiency, ambiguity, and inaccessibility of necessary information for specifying of risk assessment characteristics i.e., event reproducibility and their intensities. In this work for overcome these constraints, bow-tie fuzzy... 

    Adaptive control of robot manipulators including actuator dynamics and without joint torque measurement

    , Article 2010 IEEE International Conference on Robotics and Automation, ICRA 2010, Anchorage, AK, 3 May 2010 through 7 May 2010 ; 2010 , Pages 4639-4644 ; 10504729 (ISSN) ; 9781424450381 (ISBN) Salimi Khaligh, Y ; Namvar, M ; Sharif University of Technology
    2010
    Abstract
    Ignoring actuator dynamics in control of rigid manipulators can in practice result in performance degradation or loss of system stability. However, consideration of actuator dynamics usually requires measurement of robot joint torques. This paper addresses motion tracking control of an n-DOF rigid robot by taking into account its actuator dynamics. Joint torque measurement is avoided by using an adaptive observer. The backstepping technique is adopted to develop a dynamically smooth adaptive nonlinear controller dealing with uncertainties in manipulator and actuator dynamics. Semi-global convergence of motion tracking errors as well as torque estimation error are proven without any... 

    Heuristic Hybrid Genetic and Simulated Annealing Algorithms with Neural Networks for Task Assignment in Heterogeneous Computing Systems

    , M.Sc. Thesis Sharif University of Technology Mahdavi-Amiri, Ali (Author) ; Mahdavi Amiri, Nezamoddin (Supervisor)
    Abstract
    In this thesis, we want to present methods that are able to solve the assignment tasks problem in a heterogeneous computing system. These methods are two hybrid methods that are constructed by composing Hopefield Neural Networks with Genetic Algorithms and the Simulated Annealing. First, we solve the relaxed problem by applying Genetic Algorithms and the Simulated Annealing and we compare the results of these ways with other traditional methods. Then, we solve the constrained problem with mentioned hybrid methods. The definition of the problem is as following: Consider a distributed computing system which is comprised of set of processors with different speeds but the same structure. We want... 

    A modified ant colony system for finding the expected shortest path in networks with variable arc lengths and probabilistic nodes

    , Article Applied Soft Computing Journal ; Vol. 21, issue , August , 2014 , p. 491-500 Farhanchi, M ; Hassanzadeh, R ; Mahdavi, I ; Mahdavi-Amiri, N ; Sharif University of Technology
    2014
    Abstract
    The problem of finding the expected shortest path in stochastic networks, where the presence of each node is probabilistic and the arc lengths are random variables, have numerous applications, especially in communication networks. The problem being NP-hard we use an ant colony system (ACS) to propose a metaheuristic algorithm for finding the expected shortest path. A new local heuristic is formulated for the proposed algorithm to consider the probabilistic nodes. The arc lengths are randomly generated based on the arc length distribution functions. Examples are worked out to illustrate the applicability of the proposed approach  

    A genetic algorithm for optimization problems with fuzzy relation constraints using max-product composition

    , Article Applied Soft Computing Journal ; Volume 11, Issue 1 , 2011 , Pages 551-560 ; 15684946 (ISSN) Hassanzadeh, R ; Khorram, E ; Mahdavi, I ; Mahdavi Amiri, N ; Sharif University of Technology
    2011
    Abstract
    We consider nonlinear optimization problems constrained by a system of fuzzy relation equations. The solution set of the fuzzy relation equations being nonconvex, in general, conventional nonlinear programming methods are not practical. Here, we propose a genetic algorithm with max-product composition to obtain a near optimal solution for convex or nonconvex solution set. Test problems are constructed to evaluate the performance of the proposed algorithm showing alternative solutions obtained by our proposed model  

    A genetic optimization algorithm and perceptron learning rules for a bi-criteria parallel machine scheduling

    , Article Journal of the Chinese Institute of Industrial Engineers ; Volume 29, Issue 3 , 2012 , Pages 206-218 ; 10170669 (ISSN) Fazlollahtabar, H ; Hassanzadeh, R ; Mahdavi, I ; Mahdavi Amiri, N ; Sharif University of Technology
    2012
    Abstract
    This work considers scheduling problems minding the setup and removal times of jobs rather than processing times. For some production systems, setup times and removal times are so important to be considered independent of processing times. In general, jobs are performed according to the automatic machine processing in production systems, and the processing times are considered to be constant regardless of the process sequence. As the human factor can influence the setup and removal times, when the setup process is repetitive the setup times decreases. This fact is considered as learning effect in scheduling literature. In this study, a bi-criteria m-identical parallel machines scheduling... 

    A DEA approach for comparing solution efficiency in U-line balancing problem using goal programming

    , Article International Journal of Advanced Manufacturing Technology ; Volume 61, Issue 9-12 , August , 2012 , Pages 1161-1172 ; 02683768 (ISSN) Farkhondeh, H ; Hassanzadeh, R ; Mahdavi, I ; Mahdavi Amiri, N ; Sharif University of Technology
    Springer  2012
    Abstract
    Line balancing problem plays an important role in the decision making process to increase efficiency and productivity. Recently, U-shaped layout in many production lines has replaced the traditional straight line layout using just-in-time concept. Here, we propose a model, using multi-objective decision making approach to the U-shaped line balancing problem, to offer enhanced decision maker flexibility, by allowing for conflicting goals. The assembly line operation efficiency is the most significant aim in our study, and this efficiency relates to management of resources and the solution of line balancing problem. First, the U-shaped line balancing problem is solved considering the model's... 

    A dynamic programming approach for finding shortest chains in a fuzzy network

    , Article Applied Soft Computing Journal ; Volume 9, Issue 2 , 2009 , Pages 503-511 ; 15684946 (ISSN) Mahdavi, I ; Nourifar, R ; Heidarzade, A ; Mahdavi Amiri, N ; Sharif University of Technology
    2009
    Abstract
    Graph theory has numerous applications to problems in systems analysis, operations research, transportation, and economics. In many cases, however, some aspects of a graph-theoretic problem may be uncertain. For example, the vehicle travel time or vehicle capacity on a road network may not be known exactly. In such cases, it is natural to make use of fuzzy set theory to deal with the uncertainty. Here, we are concerned with finding shortest chains in a graph with fuzzy distance for every edge. We propose a dynamic programming approach to solve the fuzzy shortest chain problem using a suitable ranking method. By using MATLAB, two illustrative examples are worked out to demonstrate the...