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    Physicochemical and antibacterial properties of chitosan-polyvinylpyrrolidone films containing self-organized graphene oxide nanolayers

    , Article Journal of Applied Polymer Science ; Volume 133, Issue 11 , 2016 ; 00218995 (ISSN) Mahmoudi, N ; Ostadhossein, F ; Simchi, A ; Sharif University of Technology
    John Wiley and Sons Inc  2016
    Abstract
    Chitosan films have a great potential to be used for wound dressing and food-packaging applications if their physicochemical properties including water vapor permeability, optical transparency, and hydrophilicity are tailored to practical demands. To address these points, in this study, chitosan (CS) was combined with polyvinylpyrrolidone (PVP) and graphene oxide (GO) nanosheets (with a thickness of ∼1 nm and lateral dimensions of few micrometers). Flexible and transparent films with a high antibacterial capacity were prepared by solvent casting methods. By controlling the evaporation rate of the utilized solvent (1 vol % acidic acid in deionized water), self-organization of GO in the... 

    An electromagnetic design of slotless variable reluctance PM-Resolver

    , Article IEEE Transactions on Industrial Electronics ; 2022 , Pages 1-10 ; 02780046 (ISSN) Bahari, M ; Tootoonchian, F ; Mahmoudi, A ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2022
    Abstract
    This paper proposes a novel design of the variable reluctance permanent magnet (VRPM) resolvers. It utilizes a slotless stator to reduce the resolver volume. The proposed design overcomes the complex structure of windings by replacing them with magnetic flux measurement units (MFMU). The new design eliminates the computationally-expensive demodulation process of output signals by relying on none-modulated signals. An analytical model based on the nonlinear magnetic equivalent circuit (MEC) method is used to extract the output signals of the proposed resolver design. The accuracy of applied analytical model is verified against the time-stepping finite-element method (TSFEM). An optimization... 

    An electromagnetic design of slotless variable reluctance PM-Resolver

    , Article IEEE Transactions on Industrial Electronics ; Volume 70, Issue 5 , 2023 , Pages 5336-5346 ; 02780046 (ISSN) Bahari, M ; Tootoonchian, F ; Mahmoudi, A ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2023
    Abstract
    This article proposes a novel design of the variable reluctance permanent magnet (VRPM) resolvers. It utilizes a slotless stator to reduce the resolver volume. The proposed design overcomes the complex structure of windings by replacing them with magnetic flux measurement units. The new design eliminates the computationally-expensive demodulation process of output signals by relying on none-modulated signals. An analytical model based on the nonlinear magnetic equivalent circuit method is used to extract the output signals of the proposed resolver design. The accuracy of applied analytical model is verified against the time-stepping finite-element method (TSFEM). An optimization is... 

    Calcination effects on texture and porosimetric properties of regular and nano-structured alumina utilized as catalyst support for the FT Synthesis

    , Article Advanced Materials Research ; Volume 468-471 , 2012 , Pages 87-92 ; 10226680 (ISSN) Mahmoudi, M. R. H ; Kazemeini, M ; Zarkesh, J ; Khorasheh, F ; Sharif University of Technology
    2012
    Abstract
    Samples of regular gamma and nano-structured alumina were prepared and their porosimetric properties evaluated by N 2 porosimetry method. Moreover, cobalt based catalysts for Fischer-Tropsch (FT) Synthesis were prepared by loading cobalt under two calcinations using these alumina supports. Then the porosimetric properties of these materials as well as; their reactor behaviors assessed. Although the nano-structured favored the gamma alumina from pore volume and surface points of view, comparison of porosimetric properties of fresh alumina samples with corresponding catalysts prepared revealed that calcination effect in decreasing those factors was more pronounced for the nano-structured... 

    Protein corona composition of gold nanoparticles/nanorods affects amyloid beta fibrillation process

    , Article Nanoscale ; Volume 7, Issue 11 , Feb , 2015 , Pages 5004-5013 ; 20403364 (ISSN) Mirsadeghi, S ; Dinarvand, R ; Ghahremani, M. H ; Hormozi-Nezhad, M. R ; Mahmoudi, Z ; Hajipour, M. J ; Atyabi, F ; Ghavami, M ; Mahmoudi, M ; Sharif University of Technology
    Royal Society of Chemistry  2015
    Abstract
    Protein fibrillation process (e.g., from amyloid beta (Aβ) and α-synuclein) is the main cause of several catastrophic neurodegenerative diseases such as Alzheimer's and Parkinson diseases. During the past few decades, nanoparticles (NPs) were recognized as one of the most promising tools for inhibiting the progress of the disease by controlling the fibrillation kinetic process; for instance, gold NPs have a strong capability to inhibit Aβ fibrillations. It is now well understood that a layer of biomolecules would cover the surface of NPs (so called "protein corona") upon the interaction of NPs with protein sources. Due to the fact that the biological species (e.g., cells and amyloidal... 

    Graphene oxide strongly inhibits amyloid beta fibrillation

    , Article Nanoscale ; Volume 4, Issue 23 , 2012 , Pages 7322-7325 ; 20403364 (ISSN) Mahmoudi, M ; Akhavan, O ; Ghavami, M ; Rezaee, F ; Ghiasi, S. M. A ; Sharif University of Technology
    2012
    Abstract
    Since amyloid beta fibrillation (AβF) plays an important role in the development of neurodegenerative diseases, we investigated the effect of graphene oxide (GO) and their protein-coated surfaces on the kinetics of Aβ fibrillation in the aqueous solution. We showed that GO and their protein-covered surfaces delay the AβF process via adsorption of amyloid monomers. Also, the large available surface of GO sheets can delay the AβF process by adsorption of amyloid monomers. The inhibitory effect of the GO sheet was increased when we increase the concentration from 10% (in vitro; stimulated media) to 100% (in vivo; stimulated media). Conclusion: our results revealed that GO and their surface... 

    Studies of Ponceau 4R food colorant and zinc oxide nanoparticles containing it interactions with DNA and evaluation of their antimicrobial activity

    , Article Journal of Food Processing and Preservation ; Volume 46, Issue 2 , 2022 ; 01458892 (ISSN) Zangeneh Monfared, F ; Shahabadi, N ; Mahmoudi Hashemi, M ; Meibodi, F. S ; Mirjafari, Z ; Sharif University of Technology
    John Wiley and Sons Inc  2022
    Abstract
    The current study describes design and synthesis of silica-coated zinc oxide nanoparticles containing Ponceau 4R food colorant (named as ZnO@SiO2@APTMS/P4R). The interactions of Ponceau 4R and ZnO@SiO2@APTMS/P4R with calf thymus-DNA were investigated It should be noted that the competitive binding experiment revealed that both Ponceau 4R and ZnO@SiO2@APTMS/P4R could release Hoechst 33258. As inferred from the results the binding of the Ponceau 4R and ZnO@SiO2@APTMS/P4R with DNA were surface binding, mainly due to groove binding. Furthermore, antibacterial properties of ZnO, Ponceau 4R and ZnO@SiO2@APTMS/P4R samples against gram-positive bacteria and gram-negative bacteria were examined and... 

    Hyperbolic involutions and quadratic extensions

    , Article Communications in Algebra ; Volume 39, Issue 1 , Jan , 2011 , Pages 125-132 ; 00927872 (ISSN) Mahmoudi, M. G ; Sharif University of Technology
    2011
    Abstract
    This is a variation on a theme of Bayer-Fluckiger, Shapiro, and Tignol related to hyperbolic involutions. More precisely, criteria for the hyperbolicity of involutions of quadratic extensions of simple algebras and involutions of the form σ ⊗ τ and σ ⊗ ρ, where σ is an involution of a central simple algebra A, τ is the nontrivial automorphism of a quadratic extension of the center of A, and ρ is an involution of a quaternion algebra are obtained  

    On hyperbolic clifford algebras with involution

    , Article Algebra Colloquium ; Volume 20, Issue 2 , 2013 , Pages 251-260 ; 10053867 (ISSN) Mahmoudi, M. G ; Sharif University of Technology
    2013
    Abstract
    The aim of this article is to provide a characterization of quadratic forms of low dimension such that the canonical involutions of their Clifford algebras are hyperbolic  

    Orthogonal symmetries and Clifford algebras

    , Article Proceedings of the Indian Academy of Sciences: Mathematical Sciences ; Volume 120, Issue 5 , November , 2010 , Pages 535-561 ; 02534142 (ISSN) Mahmoudi, M. G ; Sharif University of Technology
    2010
    Abstract
    Involutions of the Clifford algebra of a quadratic space induced by orthogonal symmetries are investigated  

    A quick proof of the 1, 2, 4, 8 theorem

    , Article Expositiones Mathematicae ; Volume 33, Issue 3 , 2015 , Pages 375-377 ; 07230869 (ISSN) Mahmoudi, M. G ; Sharif University of Technology
    Elsevier GmbH  2015

    Products of rotations by a given angle in the orthogonal group

    , Article Bulletin of the Australian Mathematical Society ; 2017 , Pages 1-5 ; 00049727 (ISSN) Mahmoudi, M. G ; Sharif University of Technology
    2017
    Abstract
    For every rotation (Formula presented.) of the Euclidean space (Formula presented.) ((Formula presented.)), we find an upper bound for the number (Formula presented.) such that (Formula presented.) is a product of (Formula presented.) rotations by an angle (Formula presented.) ((Formula presented.)). We also find an upper bound for the number (Formula presented.) such that (Formula presented.) can be written as a product of (Formula presented.) full rotations by an angle (Formula presented.). © 2017 Australian Mathematical Publishing Association Inc  

    products of rotations by a given angle in the orthogonal group

    , Article Bulletin of the Australian Mathematical Society ; Volume 97, Issue 2 , 2018 , Pages 308-312 ; 00049727 (ISSN) Gholamzadeh Mahmoudi, M ; Sharif University of technology
    Cambridge University Press  2018
    Abstract
    For every rotation of the Euclidean space ℝ(n≥3), we find an upper bound for the number such that is a product of rotations by an angle α( 0<≤π). We also find an upper bound for the number such that ρ can be written as a product of full rotations by an angle α. © 2017 Australian Mathematical Publishing Association Inc  

    A Geometric Interpretation of the Simplicity of SO(3)

    , Article American Mathematical Monthly ; Volume 126, Issue 4 , 2019 , Pages 340-350 ; 00029890 (ISSN) Mahmoudi, M. G ; Sharif University of Technology
    Taylor and Francis Inc  2019
    Abstract
    This article aims to present a geometric interpretation of the simplicity of the rotation group of three-dimensional Euclidean space. Some historical remarks on the subject and an overview of a collection of different proofs of this result are also given  

    On normal subgroups of the unit group of a quaternion algebra over a pythagorean field

    , Article Bulletin of the Iranian Mathematical Society ; Volume 46, Issue 1 , June , 2020 , Pages 253-262 Gholamzadeh Mahmoudi, M ; Sharif University of Technology
    Springer  2020
    Abstract
    We investigate the structure of normal subgroups of the unit group of a quaternion algebra over a pythagorean field. © 2019, Iranian Mathematical Society  

    Synthesis of a nanostructured MgH2–Ti alloy composite for hydrogen storage via combined vacuum arc remelting and mechanical alloying [electronic resource]

    , Article Journal of Materials Letters ; 15 April 2011, Volume 65, Issue 7, Pages 1120–1122 Mahmoudi, N ; Kaflou, A ; Simchi, A. (Abdolreza) ; Sharif University of Technology
    Abstract
    To improve the hydrogen kinetics of magnesium hydride, TiCr1.2Fe0.6 alloy was prepared by vacuum arc remelting (VAR) and the alloy was co-milled with MgH2 to process nanostructured MgH2–5 at.% TiCr1.2Fe0.6 powder. The hydrogen desorption properties of the composite powder were studied and compared with pure magnesium hydride. X-ray diffraction (XRD) analysis showed that the composite powder prepared by VAR/mechanical alloying (MA) procedure consisted of β-MgH2, γ-MgH2, bcc Ti–Cr–Fe alloy, and small amount of MgO. The average size of particles and their grain structure after 4 h MA were determined by a laser particle size analyzer and XRD method and found to be 194 nm and 11 nm, respectively.... 

    Protein-nanoparticle interactions: Opportunities and challenges

    , Article Chemical Reviews ; Volume 111, Issue 9 , June , 2011 , Pages 5610-5637 ; 00092665 (ISSN) Mahmoudi, M ; Lynch, I ; Ejtehadi, M. R ; Monopoli, M. P ; Bombelli, F. B ; Laurent, S ; Sharif University of Technology
    2011
    Abstract
    The significant role of protein nanoparticle interactions in nanomedicine and nanotoxicity is emerging recently through the identification of the nanoparticles (NP) protein (biomolecule) corona. The dynamic layer of proteins and/or other biomolecules adsorbed to the nanoparticle surface determines how a NP interacts with living systems and thereby modifies the cellular responses to the NP. Ehrenberg and co-workers used cultured endothelium cells as a model for vascular transport of polystyrene NP with various functional groups, which showed that the capacity of the various NP surfaces to adsorb proteins was indicative of their tendency to associate with cells. The quantification of the... 

    Cytotoxicity and cell cycle effects of bare and poly(vinyl alcohol)-coated iron oxide nanoparticles in mouse fibroblasts

    , Article Advanced Engineering Materials ; Volume 11, Issue 12 , 2009 , Pages B243-B250 ; 14381656 (ISSN) Mahmoudi, M ; Simchi, A ; Vali, H ; Imani, M ; Shokrgozar, M. A ; Azadmanesh, K ; Azari, F ; Sharif University of Technology
    2009
    Abstract
    Super-paramagnetic iron oxide nanoparticles (SPIONs) are recognized as powerful biocompatible materials for use in various biomedical applications, such as drug delivery, magnetic-resonance imaging, cell/protein separation, hyperthermia and transfection. This study investigates the impact of high concentrations of SPIONs on cytotoxicity and cell-cycle effects. The interactions of surfacesaturated (via interactions with cell medium) bare SPIONs and those coated with poly(vinyl alcohol) (PVA) with adhesive mouse fibroblast cells (L929) are investigated using an MTT assay. The two SPION formulations are synthesized using a co-precipitation method. The bare and coated magnetic nanoparticles with... 

    Antibacterial Ti–Cu implants: A critical review on mechanisms of action

    , Article Materials Today Bio ; Volume 17 , 2022 ; 25900064 (ISSN) Mahmoudi, P ; Akbarpour, M. R ; Lakeh, H. B ; Jing, F ; Hadidi, M. R ; Akhavan, B ; Sharif University of Technology
    Elsevier B.V  2022
    Abstract
    Titanium (Ti) has been widely used for manufacturing of bone implants because of its mechanical properties, biological compatibility, and favorable corrosion resistance in biological environments. However, Ti implants are prone to infection (peri-implantitis) by bacteria which in extreme cases necessitate painful and costly revision surgeries. An emerging, viable solution for this problem is to use copper (Cu) as an antibacterial agent in the alloying system of Ti. The addition of copper provides excellent antibacterial activities, but the underpinning mechanisms are still obscure. This review sheds light on such mechanisms and reviews how incorporation of Cu can render Ti–Cu implants with... 

    Cell shape affects nanoparticle uptake and toxicity: An overlooked factor at the nanobio interfaces

    , Article Journal of Colloid and Interface Science ; Volume 531 , 2018 , Pages 245-252 ; 00219797 (ISSN) Farvadi, F ; Ghahremani, M. H ; Hashemi, F ; Hormozi Nezhad, M. R ; Raoufi, M ; Zanganeh, S ; Atyabi, F ; Dinarvand, R ; Mahmoudi, M ; Sharif University of Technology
    Academic Press Inc  2018
    Abstract
    Hypothesis: It is now being increasingly accepted that cells in their native tissue show different morphologies than those grown on a culture plate. Culturing cells on the conventional two-dimensional (2D) culture plates does not closely resemble the in vivo three-dimensional (3D) structure of cells which in turn seems to affect cellular function. This is one of the reasons, among many others, that nanoparticles uptake and toxicology data from 2D culture plates and in vivo environments are not correlated with one another. In this study, we offer a novel platform technology for producing more in vivo-like models of in vitro cell culture. Experiments: The normal fibroblast cells (HU02) were...