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mahmoudi--m---morteza
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Preparation and biological evaluation of [67 Ga]-labeled-superparamagnetic iron oxide nanoparticles in normal rats
, Article Journal of Nuclear Science and Technology ; Volume 97, Issue 1 , September , 2009 , Pages 51–56 ; Panahifar, A ; Mahmoudi, M. (Morteza) ; Akhlaghi, M. (Mahdi) ; Simchi, A. (Abdolreza) ; Sharif University of Technology
2009
Abstract
Gallium-67 labeled superparamagnetic iron oxide nanoparticles were prepared and evaluated for their altered biodistribution in normal rats. Superparamagnetic iron oxide nanoparticles with narrow size distribution were synthesized by co-precipitation technique using ferric and ferrous salts at molar ratio Fe3+/Fe2+=2:1 followed by structure identification using XRD, thermo gravimetric analysis , differential scanning calorimetric , vibrating sample magnetometer, high-resolution scanning electron microscopy,transmission electron microscopy and fourier transform infrared absorption techniques. In order to trace superparamagnetic iron oxide nanoparticles bio-distribution, the radiolabeled iron...
Microstructure, Properties and Kinetic Characterization in SnO2-Based Varistor with Addition of CuO Nano Particle
, M.Sc. Thesis Sharif University of Technology ; Nemati, Ali (Supervisor) ; Seyyed Reyhani, Morteza (Supervisor)
Abstract
The aim of this study is to investigate the effect of Copper oxide on the microstructure, properties, and grain growth kinetic in Tin oxide- Based varistors. Copper oxide was mixed in Tin oxide with different concentration, including 0, 0.1, 0.25, 0.5, and 1 mol% and the samples were sintered at 1250, 1300, and 1350 oC. Then, phase and microstructural characterization was investigated and consequently, electrical properties were evaluated. According to results, Copper Oxide with forming the liquid phase through the sintering process, accelerated grain growth. It was found that, by increasing concentration of CuO, mean grain size was increased from 2.6 µm in 1250 oC and 5 hours to 17.1 µm...
Determination of Protein Absorption Profile at the Surface of Biocompatible Superparamagnetic Iron Oxide Nanoparticles using Gel Electrophoresis
, M.Sc. Thesis Sharif University of Technology ; Hormozi Nezhad, Mohammad Reza (Supervisor) ; Mahmoudi, Morteza (Supervisor)
Abstract
Superparamagnetic Iron Oxide NPs (SPIONs) because of their multi-task capabilities (e.g. magnetic labeling, cell isolation, hyperthermiaand controlled drug release) have been recognized as one of the most promising NPs for theranosis applications.When NPs come in contact with a biological medium, the surfaces of them are covered by biomolecules (e.g., proteins, natural organic materials, and enzymes). Therefore, what a biological entity, such as cells, tissues, and organs, sees when interacting with NPs is different original pristine surface of the NPs and actually is hard protein corona. Shape of NPs has a great impact on proteins adsorb onto its surface and consequently on the way that...
Pyrolytic carbon coating for cytocompatibility of titanium oxide nanoparticles: a promising candidate for medical applications [electronic resource]
, Article Nanotechnology ; February 2012, Vol. 23, No. 4, PP. 045102 ; Imani, Mohammad ; Yousefi, Mohammad ; Galinetto, Pietro ; Simchi, Abdolreza ; Amiri, Houshang ; Stroeve, Pieter ; Mahmoudi, Morteza ; Sharif University of Technology
Abstract
Nanoparticles for biomedical use must be cytocompatible with the biological environment that they are exposed to. Current research has focused on the surface functionalization of nanoparticles by using proteins, polymers, thiols and other organic compounds. Here we show that inorganic nanoparticles such as titanium oxide can be coated by pyrolytic carbon (PyC) and that the coating has cytocompatible properties. Pyrolization and condensation of methane formed a thin layer of pyrolytic carbon on the titanium oxide core. The formation of the PyC shell retards coalescence and sintering of the ceramic phase. Our MTT assay shows that the PyC-coated particles are cytocompatible at employed doses
A new approach for the in vitro identification of the cytotoxicity of superparamagnetic iron oxide nanoparticles
, Article Colloids and Surfaces B: Biointerfaces ; Volume 75, Issue 1 , 1 January , 2010 , Pages 300–309 ; Simchi, A. (Abdolreza) ; Imani, M. (Mohammad) ; Shokrgozar, M. A. (Mohammad A.) ; Milani, A. S. (Abbas S.) ; Hafeli, Urs O ; Stroeve, Pieter ; Sharif University of Technology
2010
Abstract
Superparamagnetic iron oxide nanoparticles (SPIONs) are increasingly used in medical applications, such as targeting delivery and imaging. In the future, patients are more likely to be exposed to pharmaceutical products containing such particles. The study of toxicity of SPIONs has become of great importance in recent years, although the published data in this arena is limited. The aim of the present work is to investigate the cytotoxicity of SPIONs and the effect of the particles on the cell medium components. For this purpose, uncoated and polyvinyl alcohol (PVA) coated SPIONs with narrow size distribution were synthesized via a well-known coprecipitation method. The mouse fibroblast cell...
Hyperbolic involutions and quadratic extensions
, Article Communications in Algebra ; Volume 39, Issue 1 , Jan , 2011 , Pages 125-132 ; 00927872 (ISSN) ; Sharif University of Technology
2011
Abstract
This is a variation on a theme of Bayer-Fluckiger, Shapiro, and Tignol related to hyperbolic involutions. More precisely, criteria for the hyperbolicity of involutions of quadratic extensions of simple algebras and involutions of the form σ ⊗ τ and σ ⊗ ρ, where σ is an involution of a central simple algebra A, τ is the nontrivial automorphism of a quadratic extension of the center of A, and ρ is an involution of a quaternion algebra are obtained
On hyperbolic clifford algebras with involution
, Article Algebra Colloquium ; Volume 20, Issue 2 , 2013 , Pages 251-260 ; 10053867 (ISSN) ; Sharif University of Technology
2013
Abstract
The aim of this article is to provide a characterization of quadratic forms of low dimension such that the canonical involutions of their Clifford algebras are hyperbolic
Orthogonal symmetries and Clifford algebras
, Article Proceedings of the Indian Academy of Sciences: Mathematical Sciences ; Volume 120, Issue 5 , November , 2010 , Pages 535-561 ; 02534142 (ISSN) ; Sharif University of Technology
2010
Abstract
Involutions of the Clifford algebra of a quadratic space induced by orthogonal symmetries are investigated
A quick proof of the 1, 2, 4, 8 theorem
, Article Expositiones Mathematicae ; Volume 33, Issue 3 , 2015 , Pages 375-377 ; 07230869 (ISSN) ; Sharif University of Technology
Elsevier GmbH
2015
Products of rotations by a given angle in the orthogonal group
, Article Bulletin of the Australian Mathematical Society ; 2017 , Pages 1-5 ; 00049727 (ISSN) ; Sharif University of Technology
2017
Abstract
For every rotation (Formula presented.) of the Euclidean space (Formula presented.) ((Formula presented.)), we find an upper bound for the number (Formula presented.) such that (Formula presented.) is a product of (Formula presented.) rotations by an angle (Formula presented.) ((Formula presented.)). We also find an upper bound for the number (Formula presented.) such that (Formula presented.) can be written as a product of (Formula presented.) full rotations by an angle (Formula presented.). © 2017 Australian Mathematical Publishing Association Inc
A Geometric Interpretation of the Simplicity of SO(3)
, Article American Mathematical Monthly ; Volume 126, Issue 4 , 2019 , Pages 340-350 ; 00029890 (ISSN) ; Sharif University of Technology
Taylor and Francis Inc
2019
Abstract
This article aims to present a geometric interpretation of the simplicity of the rotation group of three-dimensional Euclidean space. Some historical remarks on the subject and an overview of a collection of different proofs of this result are also given
Impedance analysis of growth and morphology of electropolymerized polypyrrole nanocomposites [electronic resource]
, Article Journal of New Materials for Electrochemical Systems ; 2014, Volume 17, Number 2 ; Sadrnezhaad, S. K ; Sharif University of Technology
Abstract
Pure polypyrrole (PPy), PPy/Al2O3 and PPy/SiO2 nanocomposites synthesized galvanostatically using different polymerization charges. Electrochemical impedance measurements of pure polypyrrole revealed that the film thickness affected the impedance responses. The characteristic frequencies vs. film thickness that obtained using Cole-Cole plots showed that electrodeposition mechanism changed from 3D to 1D after nuclei overlapping for pure PPy. Analysis of the nanocomposites impedance spectrums revealed no changes during the film growth, i.e. deposition continues 3D even after nuclei overlapping. Scanning electron microscopy (SEM) confirmed the impedance results and showed that the morphology of...
The comparison of form drag and profile drag of a wind turbine blade section in pitching oscillation
, Article World Academy of Science, Engineering and Technology ; Volume 40 , 2009 , Pages 294-301 ; 2010376X (ISSN) ; Seddighi, M ; Mahmoudi, M ; Sharif University of Technology
2009
Abstract
Extensive wind tunnel tests have been conducted to investigate the unsteady flow field over and behind a 2D model of a 660 kW wind turbine blade section in pitching motion. The surface pressure and wake dynamic pressure variation at a distance of 1.5 chord length from trailing edge were measured by pressure transducers during several oscillating cycles at 3 reduced frequencies and oscillating amplitudes. Moreover, form drag and linear momentum deficit are extracted and compared at various conditions. The results show that the wake velocity field and surface pressure of the model have similar behavior before and after the airfoil beyond the static stall angle of attack. In addition, the...
Electrical and mechanical characterization of high-density polyethylene/ethylene vinyl acetate/organoclay nanocomposite
, Article IEEE Transactions on Dielectrics and Electrical Insulation ; Volume 20, Issue 5 , 2013 , Pages 1772-1779 ; 10709878 (ISSN) ; Eesaee, M ; Vakilian, M ; Sharif University of Technology
2013
Abstract
A ternary dielectric is made of high density polyethylene (HDPE) and organoclay (OC) nanocomposites, through mixing granuls of ethylene vinyl acetate (EVA). The morphological properties of nanocomposites are examined using X-ray diffraction (XRD) spectra and transmission electron microscopy (TEM) which intercalate/exfoliate morphology of clay particles. It is shown that the electrical and mechanical properties of HDPE/EVA binary blend will be enhanced significantly when OC was treated with EVA compound. The insulation material which is developed in this work can be employed to insulate the adjacent core steel sheets of a high voltage transformer
Protein corona composition of gold nanoparticles/nanorods affects amyloid beta fibrillation process
, Article Nanoscale ; Volume 7, Issue 11 , Feb , 2015 , Pages 5004-5013 ; 20403364 (ISSN) ; Dinarvand, R ; Ghahremani, M. H ; Hormozi-Nezhad, M. R ; Mahmoudi, Z ; Hajipour, M. J ; Atyabi, F ; Ghavami, M ; Mahmoudi, M ; Sharif University of Technology
Royal Society of Chemistry
2015
Abstract
Protein fibrillation process (e.g., from amyloid beta (Aβ) and α-synuclein) is the main cause of several catastrophic neurodegenerative diseases such as Alzheimer's and Parkinson diseases. During the past few decades, nanoparticles (NPs) were recognized as one of the most promising tools for inhibiting the progress of the disease by controlling the fibrillation kinetic process; for instance, gold NPs have a strong capability to inhibit Aβ fibrillations. It is now well understood that a layer of biomolecules would cover the surface of NPs (so called "protein corona") upon the interaction of NPs with protein sources. Due to the fact that the biological species (e.g., cells and amyloidal...
A recent review of waste heat recovery by Organic Rankine Cycle
, Article Applied Thermal Engineering ; Volume 143 , 2018 , Pages 660-675 ; 13594311 (ISSN) ; Fazli, M ; Morad, M. R ; Sharif University of Technology
Elsevier Ltd
2018
Abstract
The increment of using fossil fuels has caused many perilous environmental problems such as acid precipitation, global climate change and air pollution. More than 50% of the energy that is used in the world is wasted as heat. Recovering the wasted heat could increase the system efficiency and lead to lower fuel consumption and CO2 production. Organic Rankine cycle (ORC) which is a reliable technology to efficiently convert low and medium temperature heat sources into electricity, has been known as a promising solution to recover the waste heat. There are numerous studies about ORC technology in a wide range of application and condition. The main objective of this paper is to presents a...
Multi-scale Simulation of Protein Corona Formation at Nano-bio Interface in the Presence of Different Metabolites
, Ph.D. Dissertation Sharif University of Technology ; Naghdabadi, Reza (Supervisor) ; Sohrabpour, Saeid (Supervisor) ; Montazeri Hadesh, Abbas (Co-Supervisor) ; Mahmoudi, Morteza (Co-Supervisor)
Abstract
One of the most promising strategies for fighting cancer is the drug delivery process using synthetic nanoparticles. Once in biological milieu, the nanoparticle surfaces get covered with a layer of biomolecules called the “Protein Corona”. The protein corona formation changes the nanoparticles interaction with the human body dictating a new fate for them. The protein corona composition is not only dependent on the nanoparticle itself, but also it is affected by the health condition of patients as recently discovered through the experimental studies. Here, the effect of disease on the protein corona formation is discussed through the molecular dynamics simulations. A multiscale simulation...
Optimized nanoemulsion synthesis of mono-dispersed Fe3O4 magnetic nanoparticles for biomedical applications and cytotoxicity studies
, Article 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials ; 2011 ; Simchi, A ; Imani, M ; Mahmoudi, M ; Sharif University of Technology
2011
Identification of catecholamine neurotransmitters using fluorescence sensor array
, Article Analytica Chimica Acta ; Volume 917 , April , 2016 , Pages 85–92 ; 00032670 (ISSN) ; Hormozi Nezhad, M. R ; Mahmoudi, M ; Sharif University of Technology
Elsevier
2016
Abstract
A nano-based sensor array has been developed for identification and discrimination of catecholamine neurotransmitters based on optical properties of their oxidation products under alkaline conditions. To produce distinct fluorescence response patterns for individual catecholamine, quenching of thioglycolic acid functionalized cadmium telluride (CdTe) quantum dots, by oxidation products, were employed along with the variation of fluorescence spectra of oxidation products. The spectral changes were analyzed with hierarchical cluster analysis (HCA) and principal component analysis (PCA) to identify catecholamine patterns. The proposed sensor could efficiently discriminate the individual...
Identification of catecholamine neurotransmitters using fluorescence sensor array
, Article Analytica Chimica Acta ; Volume 917 , 2016 , Pages 85-92 ; 00032670 (ISSN) ; Hormozi Nezhad, M. R ; Mahmoudi, M ; Sharif University of Technology
Elsevier B.V
2016
Abstract
A nano-based sensor array has been developed for identification and discrimination of catecholamine neurotransmitters based on optical properties of their oxidation products under alkaline conditions. To produce distinct fluorescence response patterns for individual catecholamine, quenching of thioglycolic acid functionalized cadmium telluride (CdTe) quantum dots, by oxidation products, were employed along with the variation of fluorescence spectra of oxidation products. The spectral changes were analyzed with hierarchical cluster analysis (HCA) and principal component analysis (PCA) to identify catecholamine patterns. The proposed sensor could efficiently discriminate the individual...