Sharif Digital Repository

A major medical revolution that is helping us overcome some of the worst diseases, including cancer, is angiogenesis, which is based on the processes our bodies use to develop blood vessels. Most human cancers have acquired six essential capabilities: self-sufficiency in growth signals, insensitivity to growth-inhibitory signals, programmed cell death escape, unlimited replication potential, persistent angiogenesis, and tissue invasion that can induce metastasis. In other words, the defense mechanism that prevents any of these acquired capabilities must be neutralized before the cells become malignant and invasive tumors. In fact, tumors in the non-vascular growth stage can only grow up to... 

Recently complex networks, have been widely used as a model to study the behavior of human brain. By affecting different parts the brain, Neuronal disorders change the structure of functional brain networks. Investigating these changes using different graph theory metrics can be a useful methodology for human brain analysis in health and disease. Alzheimer's disease (AD) is a neural disease causing impairment in different brain activities including memory and cognition.The aim of this study is to construct the functional brain network of 17 AD patients and 17 healthy control subjects at resting state condition and analyzing them using the theory of complex networks in order to achieve a... 

The concept of entanglement exists in the common area of the quantum optics and quantum information. Quantum optics is the best tools for investigating of this quantum informational phenomenon experimentally. One of the instruments that let us observes experimentally macroscopy entangeled state is Fabry-Perot Cavity. Striking of photons with the mirror of cavity transfer effective mommentom to it, and oscilating of mirror creates new modes: stocks and anti-stocks modes. Studing quantum state of these modes shows the entangling between photon and phonon (oscilating of mirror) modes. We assume that light beam enters the cavity from a semi-transparent mirror. So cavity is the system with... 

In this project a heat pipe heat exchanger is designed for using in an organic rankine cycle. The cycle parameter and heat exchanger parameter are optimized at the same time. The cycle is optimized in three scenario and the results are compared. In the first scenario the objective function is the net power output of the cycle, in the second scenario the objective function is the ratio of net power output and heat transfer area(POPA) and the objective function of third optimization is POPA and exergy destruction rate(EDR). With first scenario as base case, in second scenario POPA is increased 94% and in second scenario EDR and POPA are increased 9% and 75% respectively. The results show that... 

This study aimed to model pore water pressure in embankment dams using advanced machine learning methods, seeking to improve prediction accuracy by integrating diverse temporal and spatial variables. Data from the Masjed Soleyman Dam, covering the years 2003 to 2024, were used. Initially, the data were cleaned and organized, leading to the introduction of six scenarios based on usable data: two scenarios with pressure gauge inputs, two with piezometer inputs, and two with combined pressure gauge–piezometer inputs. Additional scenarios were later introduced to further refine the analysis. The study employed individual models, including Artificial Neural Networks (ANN), Long Short-Term Memory... 

Surface phenomena and dynamic interfacial properties plays a significant role in multiphase gas-liquid & liquid-liquid processes applied in different industrial applications. However, current laboratory equipment and represented methods for dynamic and unsteady state condition caused by motivation of interface of two phases (like rising bubble), in purpose of qualitative investigation of interphase properties are not satisfying enough. Also, common modeling methods are represented with lots of modified assumptions which are not validated properly with experimental results. In current thesis, with development of laboratory tools and applying the “rising bubble method” for investigating the... 

Given the growing advantage of exploiting renewable energy resources over fossil fuels and using distributed generation systems, microgrids seem to be the best solution for reaching the energy-efficient world of the future. Hybrid microgrids are the best options among all other types of microgrids because they make it possible to use AC and DC sources and loads together and at the same time. Since connecting AC and DC sections of a hybrid microgrid leads to the interaction between them, proper control of interlinking converter(s) is crucial for the reliable and stable operation of the entire microgrid. In this study, small signal model of a hybrid AC/DC microgrid consisting of static and... 

The present study has been performed for better understanding about the dynamic behavior of fluid interfaces in presence of surfactants, nanoparticles and their interactions in gas-liquid dispersion systems. One of the main purposes of this work is to investigate the influence of surface modified nanoparticles on the dynamic behavior of gas-liquid interfaces. For this purpose, the rising bubble experiment was used as one of the most conventional procedures. Local velocities of bubbles rising in nanoparticle solutions were determined experimentally. Influences of silica nanoparticles which were modified via three approaches were investigated in these experiments. Heat treatment was applied to... 

Bacteria are the first organisms, and ath the same time, the most diverse forms of life that appeared on the earth and without their functions living on the earth would not be possible. Therefore, recognition of bacteria is greatly important and can lead to the recognition of new genes, production of new antibiotics and anti-cancer compounds, etc. The problem of identifying the bacterial genome from DNA sequences obtained directly from environmental samples is known as Metagenomics. One of the main stages of Metagenomics is the binning of genetic components and because bio-marker based binning methods are only able to bin 1% of bacterial species, bio-marker free methods have been considered... 

The electro-elastic fields of nano-sized piezoelectric structures are considered based on the non-classical continuum theory. Nowadays because of increasing the application of piezoelectric materials in nano technology and exclusive properties of this kind of materials, they can use as the ingredients of electromechanical systems. Therefore, the determination of induced electro-mechanical fields is important. In this study the constitutive equations based on non-classical continuum theory and general anisotropy for the elastic, piezoelectric and dielectric tensors are considered, and the electromechanical fields are determined using the micromechanical method. Furthermore, the size effects... 

Surface phenomena is one of the fundamental branches of science that has many applications in industries related to multiphase processes. One of the most important issues of this knowledge is inter-phase transport phenomena in contacting gas - liquid and liquid – liquid systems. Multiphase systems generally include dispersions such that in many cases are associated with the relative motion between the continuous and dispersed phase. One of the most widely used inter-phase flow systems is dispersion of gas bubbles in the bulk of liquid. The overall efficiency of these systems is often determined by the characteristics of the gas phase. In order to understand the dynamic behavior of such... 

Signal transmission of information on noiseless and lossy channels is an important issue in data transmission. Using the amplifier in the transmission channels is a good solution to help send information on longer channels. In classical communication, information can be coded in the amplitude or phase of the field and an amplifier is responsible for amplifying these parameters. If we consider the conditions ideal and ignore electrical noises, Classical mechanics does not impose any restrictions on the amplification of arbitrary classical signals. Instead, in quantum telecommunications the information encoded on the quadrature of the electromagnetic field are mounted on quantum states, such... 

This study investigated the relationships between team identification and attendance intention in Iranian football matches, specifically examining the impact of constraints on this relationship. The research focused on Esteghlal Football Club, one of Iran's most popular teams, which faces a paradox of having a large fan base (35-40 million supporters) but relatively low stadium attendance rates (below 50% capacity). The study employed a mixed online sampling method (convenience and snowball) with 182 Esteghlal fans who had attended at least one stadium match. Data was collected using three validated questionnaires: team identification (18 items, 6 dimensions), attendance intention (4 items,...