Sharif Digital Repository

Isoquinolinonese are important structural compounds in plant alkaloids and useful synthetic intermediates for bio logically active compound some 3(2H)-isoquinolinone are known to exhibit biological effects such as antidepressant, cardiotonic, or analgesic activity. 3(2H)-isoquinolinone and its derivative are not so readily accessible. They have previously been synthesized by the reaction of o-acylphenyl acetic with ammonia, reaction of 3-isochromanon with amines this methods have problems like low yield and because of that we have developed practical and efficient route to synthesis 1٬4 dihydroisoquin-3(2H)-ones under microwave irradiation. We did this project with modified Pictet-Spengler... 

One of the most challengeable topic in the field of green chemistry is the synthesis of organic structure in water. In this project immobilized glucose on Fe3O4 was prepared as a nano heterogeneous dispersive catalyst in water. The catalyst was fully characterized by FT-IR, TGA, CHN, SEM, EDX and atomic absorption spectroscopy. The synthesized catalyst was used in the synthesis of different derivatives of 1,2,3-triazole via one-pot three component reaction of alkynes, alkyl halides, sodium azides; And to the best of our knowledge this novel catalyst coin sides to the principles of green chemistry. This nano catalyst can be recycled and reused for several runs without significant loss of its... 

It is more than a century to study qualitative and quantitative behavior of structures against earthquakes will be benefited from laboratory studies. In fact, the best method for observing the behavior of a structure during an earthquake is earthquake simulation on the structure. Today, the most effective way to do these tests is simulating of earthquake by using of Shaking Table. The shaking table consists of three main parts: electronic, hydraulic and mechanical. The accuracy of earthquake simulation’s results are very important. In recent years, numerous studies on the dynamic behavior of the above components and the interactions between these components are performed. In this study, we... 

Considering the role of fluid storage tanks within or after an earthquake and the irreparable damages from their destruction that arise from the nature of the fluids of flammable or toxic nature stored in those tanks, it is very important to ensure stability and durability of the tanks when an earthquake is occurring. One of the most important damages to storage tanks within the past earthquakes has been lack of stability of their walls taking place in the form of elephant buckling. A certain storage tank was subject to a case study in this research and the tank's body, foundation, anchorages, the tread between the fluid and tank's body and between the bottom sheet and foundation were... 

Fused pyrimidines have attracted considerable attention recently in synthetic organic chemistry because of their wide range of biological activities pharmaceutical, therapeutic properties, antibacterial, antiviral, antitumor, and anti-inflammatory activities. We have reported a new and efficient synthesis of dihydro and tetrahydro pyrimidines fused to 2H-chromen-2-oneand cyclohex-2-enone and pyrimidine fused to uracil via two component reaction of 4-amino-2H-chromen-2-one, 3-aminocyclohex-2-enone and6-aminouracilto 1-aryl-N,N'-bis(arylmethylene)methanediaminein the present of iodine as catalyst.Molecular iodine has received considerable attention in the last few years due to inexpensive,... 

The observed response of medium rise buildings during sever earthquakes worldwide has indicated that RC buildings with shear walls behave considerably better than other buildings. The conviction that shear walls are inherently brittle still prevails amongst engineers, and therefore, they usually prefer to choose moment resisting RC frames without shear walls. In this study, a number of RC frames, with and without shear walls are designed in accordance with the seismic codes, and are then subjected to an assemble of severe earthquakes. The results of timehistory nonlinear analyses of these models are then used to investigate the effect of the presence of shear walls within the framework of... 

The paper presents the results nonlinear analysis of steel base plates subjected to different combinations of axial and bending forces. The bending forces range from small moments representing small eccentricities to large moments from seismic actions. The results of analyses proved to be in good agreement with experiments. The parameters investigated in this study are as follows: distribution of strain and stresses in the concrete foundation and the steel plate, the strains and stresses in the tensile anchorage bolts, the location of neutral curve under the base plate, the centre of compressional reaction forces in concrete, the flextural rigidity of the base plate connection, and the axial... 

By investigating reports of severe and destructive earthquakes of the past years we have realized that shear-wall structures most of the times had better seismic performance and more reliability than moment resistance frames. Asymmetrical arrangement of shear walls due to architectural limitations caused distortions in the structure. On the other hand, seismic regulation don’t compliance existence of twisting moment in the structures. What was said are all the most important reasons for not employing asymmetric shear wall sets in the structures by designers. The purpose of this study is to compare the seismic behavior of symmetric moment frame structures with seismic behavior of symmetric...