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    Toward a computer aided diagnosis system for lumbar disc herniation disease based on MR images analysis

    , Article Biomedical Engineering - Applications, Basis and Communications ; Volume 28, Issue 6 , 2016 ; 10162372 (ISSN) Nikravan, M ; Ebrahimzadeh, E ; Izadi, M. R ; Mikaeili, M ; Sharif University of Technology
    World Scientific Publishing Co. Pte Ltd  2016
    Abstract
    Lumbar disc diseases are the commonest complaint of Lower Back Pain (LBP). In this paper, a new method for automatic diagnosis of lumbar disc herniation is proposed which is based on clinical Magnetic Resonance Images (MRI) data. We use T2-W sagittal and myelograph images. Our method uses Otsu thresholding method to extract the spinal cord from MR images of Lumbar disc. In the next step, a third-order polynomial is aligned on the extracted spinal cords, and in the end of preprocessing step all the T2-W sagittal images are prepared for extracting disc boundary and labeling. After labeling and extracting a ROI for each disc, intensity and shape features are used for classification. The... 

    Virtue Epistemology of Linda Zagzebski’s Point of View

    , M.Sc. Thesis Sharif University of Technology Mikaeili, Zahra (Author) ; Miandari, Hassan (Supervisor)
    Abstract
    There are mainly two major issues in contemporary epistemology: knowledge and justification. Many necessary and sufficient conditions have been suggested in order to define “knowledge”. Knowledge often has been defined as “justified true belief”. But Gettier by some counter examples showed that these conditions are not sufficient for knowledge’s analysis. Many different answers are offered to solve Gettier’s problems. Theories about justification can be divided into two classes: internalist and externalist. Virtue epistemology is a new approach in epistemology that focus on epistemic and moral virtues. It seems that Linda Zagzebski is one of the best theorists in this approach. In this... 

    XFEM, strong discontinuities and second-order work in shear band modeling of saturated porous media

    , Article Acta Geotechnica ; Volume 13, Issue 6 , 2018 , Pages 1249-1264 ; 18611125 (ISSN) Mikaeili, E ; Schrefler, B ; Sharif University of Technology
    2018
    Abstract
    We investigate shear band initiation and propagation in fully saturated porous media by means of a combination of strong discontinuities (discontinuities in the displacement field) and XFEM. As a constitutive behavior of the solid phase, a Drucker–Prager model is used within a framework of non-associated plasticity to account for dilation of the sample. Strong discontinuities circumvent the difficulties which appear when trying to model shear band formation in the context of classical nonlinear continuum mechanics and when trying to resolve them with classical numerical methods like the finite element method. XFEM, on the other hand, is well suited to deal with problems where a discontinuity... 

    Numerical modeling of shear band propagation in porous plastic dilatant materials by XFEM

    , Article Theoretical and Applied Fracture Mechanics ; Volume 95 , 2018 , Pages 164-176 ; 01678442 (ISSN) Mikaeili, E ; Liu, P ; Sharif University of Technology
    Elsevier B.V  2018
    Abstract
    This paper studies mixed-mode shear band propagation behaviors in porous plastic dilatant materials by the extended finite element method (XFEM). The Drucker-Prager elastoplastic model is combined with the strong discontinuity method to simulate the dilatant shear band. First, the dissipative nature of the localized area with displacement jump is integrated into the constitutive model by introducing a cohesive law. A new contribution lies that the yielding function is modified in the localized region to calculate the cohesive traction within the framework of the XFEM. The shear band propagation direction is determined by the singularity of the acoustic tensor and the corresponding... 

    Modeling Shear Band Propagation in Saturated Porous Media Using eXtended Finite Element Method

    , M.Sc. Thesis Sharif University of Technology Mikaeili, Ehsan (Author) ; Kazemi, Mohammad Taghi (Supervisor)
    Abstract
    Shear band is more relevant in porous medias rather than continuum media. Shear band is a narrow region of solid experiencing intense shearing. After initiation of shear band, the sliding on two sides of the band occurs. The area inside the shear band undergoes extreme plastic deformation, while experiences elastic unloading outside of the band. In porous materials, the direction of slip and discontinuity in displacement field is not same, as a result of dilation. In fact dilation requires an increase in the volume of the shear band zone. The main difficulty in modeling the shear band is that the width of shear band in contrast to the dimension of the media, is too small. Consequently, the... 

    Dose-dependent effects of nanoscale graphene oxide on reproduction capability of mammals

    , Article Carbon ; Volume 95 , December , 2015 , Pages 309-317 ; 00086223 (ISSN) Akhavan, O ; Ghaderi, E ; Hashemi, E ; Akbari, E ; Sharif University of Technology
    Elsevier Ltd  2015
    Abstract
    In vivo dose-dependent effects of nanoscale graphene oxide (NGO) sheets on reproduction capability of Balb/C mice were investigated. Biodistribution study of the NGO sheets (intravenously injected into male mice at dose of ∼2000 μg/mL or 4 mg/kg of body weight) showed a high graphene uptake in testis. Hence, in vivo effects of the NGO sheets on important characteristics of spermatozoa (including their viability, morphology, kinetics, DNA damage and chromosomal aberration) were evaluated. Significant in vivo effects was found at the injected concentrations ≥200 μg/mL after (e.g., ∼45% reduction in sperm viability and motility at 2000 μg/mL). Observation of remarkable DNA fragmentations and... 

    Accelerated differentiation of neural stem cells into neurons on ginseng-reduced graphene oxide sheets

    , Article Carbon ; Volume 66 , January , 2014 , Pages 395-406 Akhavan, O ; Ghaderi, E ; Abouei, E ; Hatamie, S ; Ghasemi, E ; Sharif University of Technology
    2014
    Abstract
    Asian red ginseng was used for green reduction of chemically exfoliated graphene oxide (GO) into reduced graphene oxide (rGO). The reduction level and electrical conductivity of the ginseng-rGO sheets were comparable to those of hydrazine-rGO ones. Reduction by ginseng resulted in repairing the sp 2 graphitic structure of the rGO, while hydrazine-rGO showed more defects and/or smaller aromatic domains. The ginseng-rGO sheets presented a better stability against aggregation than the hydrazine-rGO ones in an aqueous suspension. Whilst the hydrophobic hydrazine-rGO films exhibited no toxicity against human neural stem cells (hNSCs), the hydrophilic GO and ginseng-rGO films (as more... 

    Contested framings and policy controversies: Analysing biosafety policy-making in Iran

    , Article Science and Public Policy ; Volume 40, Issue 5 , 2013 , Pages 616-627 ; 03023427 (ISSN) Kashani, E. S ; Millstone, E ; Sharif University of Technology
    2013
    Abstract
    Vigorous debates have taken place within and between many countries about regulatory policy regimes covering the assessment and approval of genetically modified (GM) crops. In Iran, a very vigorous and hotly contested policy debate concerning legislation covering GM crops occurred between 2004 and 2009, but it was confined within government circles with almost no public discussion. This paper analyses the Iranian policy-making process in the period 2006-9. It explains how and why a stalemate arose in disputes between ministries and departments. The chosen analytical framework draws mainly on the regulation of technological risks and the analysis of public policy-making. It deploys the... 

    On the possible volumes of μ-way latin trades

    , Article Aequationes Mathematicae ; Volume 63, Issue 3 , 2002 , Pages 303-320 ; 00019054 (ISSN) Adams, P ; Billington, E. J ; Bryant, D. E ; Mahmoodian, E. S ; Sharif University of Technology
    Birkhauser Verlag Basel  2002
    Abstract
    A μ-way latin trade of volume s is a set of μ partial latin rectangles (of inconsequential size) containing exactly the same s filled cells, such that if cell (i, j) is filled, it contains a different entry in each of the μ partial latin rectangles, and such that row i in each of the μ partial latin rectangles contains, set-wise, the same symbols and column j, likewise. In this paper we show that all μ-way latin trades with sufficiently large volumes exist, and state some theorems on the non-existence of μ-way latin trades of certain volumes. We also find the set of possible volumes (that is, the volume spectrum) of μ-way latin trades for μ = 4 and 5. (The case μ = 2 was dealt with by Fu,... 

    The three-way intersection problem for latin squares

    , Article Discrete Mathematics ; Volume 243, Issue 1-3 , 2002 , Pages 1-19 ; 0012365X (ISSN) Adams, P ; Billington, E. J ; Bryant, D. E ; Mahmoodian, E. S ; Sharif University of Technology
    2002
    Abstract
    The set of integers k for which there exist three latin squares of order n having precisely k cells identical, with their remaining n2 -k cells different in all three latin squares, denoted by I3[n], is determined here for all orders n. In particular, it is shown that I3[n] = {0,.,n2 -15}U [n2 - 12,n2-9,n2], for n ≫8. ©2002 Eisevier Science B.V. All rights reserved  

    Integration of spatial fuzzy clustering with level set for segmentation of 2-D angiogram

    , Article IECBES 2014, Conference Proceedings - 2014 IEEE Conference on Biomedical Engineering and Sciences: "Miri, Where Engineering in Medicine and Biology and Humanity Meet", 8 December 2014 through 10 December 2014 ; December , 2015 , Pages 309-314 ; 9781479940844 (ISBN) Ghalehnovi, M ; Zahedi, E ; Fatemizadeh, E ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2015
    Abstract
    Coronary angiography is a vital instrument to detect the prevailing of vascular diseases, and accurate vascular segmentation acts a crucial role for proper quantitative analysis of the vascular tree morphological features. Level set methods are popular for segmenting the coronary arteries, but their performance is related to suitable start-up and optimum setting of regulating parameters, essentially done manually. This research presents a novel fuzzy level set procedure with the objective of segmentation of the coronary artery tree in 2-D X-ray angiography as automatically. It is clever to clearly develop from the early segmentation with spatial fuzzy grouping. The adjusting parameters of... 

    Deep relative attributes

    , Article 13th Asian Conference on Computer Vision, ACCV 2016, 20 November 2016 through 24 November 2016 ; Volume 10115 LNCS , 2017 , Pages 118-133 ; 03029743 (ISSN); 9783319541921 (ISBN) Souri, Y ; Noury, E ; Adeli, E ; Sharif University of Technology
    Springer Verlag  2017
    Abstract
    Visual attributes are great means of describing images or scenes, in a way both humans and computers understand. In order to establish a correspondence between images and to be able to compare the strength of each property between images, relative attributes were introduced. However, since their introduction, hand-crafted and engineered features were used to learn increasingly complex models for the problem of relative attributes. This limits the applicability of those methods for more realistic cases. We introduce a deep neural network architecture for the task of relative attribute prediction. A convolutional neural network (ConvNet) is adopted to learn the features by including an... 

    A public code for astrometric microlensing with contour integration

    , Article Monthly Notices of the Royal Astronomical Society ; Volume 505, Issue 1 , 2021 , Pages 126-135 ; 00358711 (ISSN) Bozza, V ; Khalouei, E ; Bachelet, E ; Sharif University of Technology
    Oxford University Press  2021
    Abstract
    We present the first public code for the calculation of the astrometric centroid shift occurring during microlensing events. The computation is based on the contour integration scheme and covers single and binary lensing of finite sources with arbitrary limb darkening profiles. This allows for general detailed investigations of the impact of finite source size in astrometric binary microlensing. The new code is embedded in version 3.0 of vbbinarylensing, which offers a powerful computational tool for extensive studies of microlensing data from current surveys and future space missions. © 2021 The Author(s) Published by Oxford University Press on behalf of Royal Astronomical Society  

    Toward electrically tunable, lithography-free, ultra-thin color filters covering the whole visible spectrum

    , Article Scientific Reports ; Volume 8, Issue 1 , 2018 ; 20452322 (ISSN) Aalizadeh, M ; Serebryannikov, A. E ; Khavasi, A ; Vandenbosch, G. A. E ; Ozbay, E ; Sharif University of Technology
    Nature Publishing Group  2018
    Abstract
    The possibility of real-time tuning of optical devices has attracted a lot of interest over the last decade. At the same time, coming up with simple lithography-free structures has always been a challenge in the design of large-area compatible devices. In this work, we present the concept and the sample design of an electrically tunable, lithography-free, ultra-thin transmission-mode color filter, the spectrum of which continuously covers the whole visible region. A simple Metal-Insulator-Metal (MIM) cavity configuration is used. It is shown that using the electro-optic dielectric material of 4-dimethyl-amino-N-methyl-4-stilbazoliumtosylate (DAST) as the dielectric layer in this... 

    A novel method for modeling the magnetizing yoke

    , Article Electromagnetics ; Volume 30, Issue 3 , 2010 , Pages 297-308 ; 02726343 (ISSN) Ravanbod, H ; Norouzi, E
    2010
    Abstract
    Magnetic flux leakage is the most widely used method for oil and gas pipeline non destructive testing. The saturation level of the sample under test has a significant effect on its efficiency; therefore, the magnetizing yoke requires an elaborate design. The finite element method is the conventional approach used for this purpose, but it is very time consuming. In this article, a neuro-fuzzy method is presented to model the behavior of the magnetizing yoke. Modeling a few different designs with the finite element method and using the results for training the neuro-fuzzy model eradicates the necessity of modeling a huge number of designs with the finite element method. The acquired... 

    On decomposing complete tripartite graphs into 5-cycles

    , Article Australasian Journal of Combinatorics ; Volume 54, Issue 2 , 2012 , Pages 289-301 ; 10344942 (ISSN) Alipour, S ; Mahmoodian, E. S ; Mollaahmadi, E ; Sharif University of Technology
    AJC  2012
    Abstract
    The problem of finding necessary and sufficient conditions to decompose a complete tripartite graph K(r, s, t) into 5-cycles was first considered by Mahmoodian and Mirzakhani (1995). They stated some necessary conditions and conjectured that these conditions are also sufficient. Since then, many cases of the problem have been solved by various authors; however the case when the partite sets r ≤ s ≤ t have odd and distinct sizes remains open. A necessary condition is t ≤ 3r. Billington and Cavenagh (2011) have shown that when r, s, and t are all odd and r ≤ s ≤ t ≤ κr, where κ ≈ 1.0806, then the conjectured necessary conditions for decomposing are also sufficient. We extend this result... 

    Ultra-sensitive detection of leukemia by graphene

    , Article Nanoscale ; Vol. 6, issue. 24 , Dec , 2014 , p. 14810-14819 Akhavan, O ; Ghaderi, E ; Hashemi, E ; Rahighi, R ; Sharif Universit of Technology
    2014
    Abstract
    Graphene oxide nanoplatelets (GONPs) with extremely sharp edges (lateral dimensions ∼20-200 nm and thicknesses <2 nm) were applied in extraction of the overexpressed guanine synthesized in the cytoplasm of leukemia cells. The blood serums containing the extracted guanine were used in differential pulse voltammetry (DPV) with reduced graphene oxide nanowall (rGONW) electrodes to develop fast and ultra-sensitive electrochemical detection of leukemia cells at leukemia fractions (LFs) of ∼10-11 (as the lower detection limit). The stability of the DPV signals obtained by oxidation of the extracted guanine on the rGONWs was studied after 20 cycles. Without the guanine extraction, the DPV peaks... 

    Specific picomolar detection of a breast cancer biomarker her-2/neu protein in serum: electrocatalytically amplified electroanalysis by the aptamer/peg-modified electrode

    , Article ChemElectroChem ; Volume 4, Issue 4 , 2017 , Pages 872-879 ; 21960216 (ISSN) Salimian, R ; Kékedy Nagy, L ; Ferapontova, E. E ; Sharif University of Technology
    Wiley-VCH Verlag  2017
    Abstract
    Specific and sensitive electroanalysis of blood-circulating protein cancer biomarkers is often complicated by interference from serum proteins nonspecifically adsorbing at the biosensing interface and masking specific reactions of interest. Here, we have developed an electrocatalytically amplified assay for specific and sensitive analysis of human epidermal growth factor receptor-2 (HER-2/neu, a protein cancer biomarker over-expressed in breast cancers) that allows us to avoid both the interference from bovine serum albumin (BSA) and electrocatalytic amplification of the signal stemming from the specific aptamer−HER-2/neu binding. A HER-2/neu-specific thiolated aptamer sequence was... 

    A two layer texture modeling based on curvelet transform and spiculated lesion filters for recognizing architectural distortion in mammograms

    , Article Middle East Conference on Biomedical Engineering, MECBME ; 17 - 20 February , 2014 , pp. 21-24 Khoubani, S ; Nadjar, H. S ; Fatemizadeh, E ; Mohammadi, E ; Sharif University of Technology
    2014
    Abstract
    This paper presents a two layer texture modeling method to recognize architectural distortion in mammograms. We propose a method that models a Gaussian mixture on the Curvelet coefficients and the outputs of Spiculated Lesion Filters. The Curvelet transform and the Spiculated Lesion Filters have been applied to extract textural features of mammograms in literature. However the key difference between this study and the previous ones is that in our approach, a Gaussian mixture models the textural features extracted by the Curvelet transform and the Spiculated Lesion Filters. The results of the current study are shown in the form of accuracy and the area under the receiver operating... 

    CFD-aided simulation of frost growth inside a narrow duct with uniform wall temperature variation

    , Article ASME 2014 12th International Conference on Nanochannels, Microchannels, and Minichannels, ICNMM 2014, Collocated with the ASME 2014 4th Joint US-European Fluids Engineering Division Summer Meeting ; 2014 ; ISBN: 9780791846278 Darbandi, M ; Asgari, E ; Hajikaram, M ; Schneider, G. E ; Sharif University of Technology
    2014
    Abstract
    In this paper, we study the frost formation and growth at the walls of a duct with uniform wall temperature variation. The simulation is performed for laminar flow regime considering suitable semi-empirical models incorporated with computational fluid dynamics (CFD) method. The frost growth is considered to be normal to the duct surface. Since the duct aspect ratio is high, we perform our simulations in two-dimensional zones. To simulate the frost layer properly, we solve both the energy and mass balance equations implementing some semi-empirical correlations on the frost side. At this stage, we suitably predict the required heat flux value at the solid boundary and the heat transfer...