Sharif Digital Repository

In this research, the effect of surface characteristics on boiling heat transfer has been investigated experimentally. For this purpose, a device with the ability to automatically record the liquid temperature of the inlet and outlet of the test area, calculate the coefficient of boiling heat transfer, and heat flux has been developed. The automatic temperature stability of the working fluid and the ability to investigate the effect of surfaces with different characteristics (in terms of material and surface structure) on the boiling heat transfer parameters are the most important features of this device. The performance of the experimental setup was evaluated by the modified "Chen" equation... 

The performance of nanoparticles for biomedical applications is often assessed by their narrow size distribution, suitable magnetic saturation and low toxicity effects. In this work, superparamagnetic iron oxide nanoparticles (SPIONs) with different size, shape and saturation magnetization levels were synthesized via a co-precipitation technique using ferrous salts with a Fe3+/Fe2+ mole ratio equal to 2. A parametric study is conducted, based on a uniform design-of-experiments methodology and a critical polymer/iron mass ratio (r-ratio) for obtaining SPION with narrow size distribution, suitable magnetic saturation, and optimum biocompatibility is identified. Polyvinyl alcohol (PVA) has been... 

In recent years, the fabrication of nanoparticles and exploration of their properties have attracted the attention of physicists, chemists, biologists and engineers. Interest in nanoparticles arise from the fact that the mechanical, chemical, electrical, optical, magnetic, electro-optical and magneto-optical properties of these particles are different from their bulk properties and depend on the particle size. There are numerous areas where nanoparticulate systems are of scientific and technological interest. This new book reviews research on the various components of superparamagnetic iron oxide nanoparticles  

As the use of superparamagnetic iron oxide nanoparticles (SPION) in biomedical applications increases (e.g. for targeting drug delivery and imaging), patients are likely to be exposed to products containing SPION. Despite their high biomedical importance, toxicity data for SPION are limited to date. The aim of this study is to investigate the cytotoxicity of SPION and its ability to change cell medium components. Bare and poly(ethylene glycol)-co-fumarate (PEGF)-coated SPION with narrow size distributions were synthesized. The particles were prepared by co-precipitation using ferric and ferrous salts with a molar Fe3+/Fe2+ ratio of 2. Dulbecco's modified Eagle's medium (DMEM) and primary... 

Superparamagnetic iron oxide nanoparticles (SPION) with narrow size distribution and stabilized by polyvinyl alcohol (PVA) were synthesized. The particles were prepared by a coprecipitation technique using ferric and ferrous salts with a molar Fe3+/Fe2+ ratio of 2. Using a design of experiments (DOE) approach, the effect of different synthesis parameters (stirring rate and base molarity) on the structure, morphology, saturation magnetization, purity, size, and size distribution of the synthesized magnetite nanoparticles was studied by various analysis techniques including X-ray powder diffraction (XRD), thermogravimetric analysis (TGA) with differential scanning calorimetry (DSC)... 

For risk free application of nanoparticles in life science, energy and the environment, it is essential to understand their biological fate and potential toxicity. The application of iron oxide nanoparticles for drug delivery has been one of the most promising researches in the field of nanotechnology. However, there are two major problems associated with magnetically targeted deliveries that still need close attention: • As the drug is coated on to the particle surfaces, there is the possibility of faster drug release (Burst Effect). Therefore, after reaching to the specific site, there is very low amount of drug for delivery. To overcome this problem, some researchers have used conjugation... 

In transition from concept design to detail design, designers and engineers need to find specific materials to optimize performance of the systems. The large number of materials and the wide range of manufacturing processes cause engineers always to seek new materials selection methods. In this research work a new method so called QFD method, which employs materials indices, is introduced. The method enjoys a combination of Ashby's materials selection concepts with the Quality Function Deployment (QFD) tool. The QFD method, which is modified here to fit the materials selection field, provides the designer with the required weighting factors for the material indices. Incorporation of House of... 

In this paper, an innovative method is proposed for material selection. This method is based on the well-known weighting properties approach while integrating a new exponential function in the method to overcome the deficiencies of previously proposed methods. Using a maximum and minimum, in each significant aspect of the problem, for scaling, the values of material properties and achieving more realistic results by not emphasizing on any of the high and low extremes and using an exponential function that ranks the candidates regardless of their number, for improving the performance of the methodology and obtaining more absolute rankings, are some of the advantages of this method. The... 

Superparamagnetic iron oxide nanoparticles (SPIONs) are increasingly used in medical applications, such as targeting delivery and imaging. In the future, patients are more likely to be exposed to pharmaceutical products containing such particles. The study of toxicity of SPIONs has become of great importance in recent years, although the published data in this arena is limited. The aim of the present work is to investigate the cytotoxicity of SPIONs and the effect of the particles on the cell medium components. For this purpose, uncoated and polyvinyl alcohol (PVA) coated SPIONs with narrow size distribution were synthesized via a well-known coprecipitation method. The mouse fibroblast cell... 

In this research, the effect of surface characteristics on boiling heat transfer has been investigated experimentally. For this purpose, a device with the ability to automatically record the liquid temperature of the inlet and outlet of the test area, calculate the coefficient of boiling heat transfer, and heat flux has been developed. The automatic temperature stability of the working fluid and the ability to investigate the effect of surfaces with different characteristics (in terms of material and surface structure) on the boiling heat transfer parameters are the most important features of this device. The performance of the experimental setup was evaluated by the modified "Chen" equation... 

This study investigated the behavior of ferrofluids containing superparamagnetic iron oxide nanoparticles (SPION) of various compositions for potential applications in drug delivery and imaging. To ensure biocompatibility, the interaction of these SPION with two cell lines (adhesive and suspended) was also investigated using an MTT (3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide) assay. The cell lines studied were primary mouse connective tissue cells (adhesive) and human leukemia cells (suspended). SPION were synthesized with a co-precipitation method under different stirring rates and NaOH molarities. The SPION demonstrated a range of magnetic saturations due to their... 

In this research, the galvanized steel with thickness of 2 mm was joined to the 5754 aluminum alloy with thickness of 3 mm by the cold metal transfer MIG welding–brazing process. The effect of the filler wires (AlSi3Mn, AlSi5, and AlSi12) and wire feed speeds (4.7, 5, and 5.3 m/min) on metallurgical and mechanical properties have been discussed. According to the experimental results, thickness of intermetallic compound (IMC) layer which was formed along the interface during the MIG welding–brazing was varied by changing of parameters. In addition, the results indicated that by increasing of the wire feed speed, the thickness of IMC layer at first decreased and then increased. Results... 

Reliability evaluations play a significant role in engineering applications to ensure the serviceability and safety of advanced structures such as those made of composites. Here, a dynamic reliability evaluation analysis based on the probability density evolution Method (PDEM) has been adapted to assess the reliability of composite structures under uncertainties within the material properties and the external loadings. A Back-Propagation Neural Network approach is employed to identify the system's nonlinear structural response, which is often the case under large deformations. To exemplify, a split Hopkinson pressure bar system was employed to mimic the mechanical behavior of a... 

Reliability evaluations play a significant role in engineering applications to ensure the serviceability and safety of advanced structures such as those made of composites. Here, a dynamic reliability evaluation analysis based on the probability density evolution Method (PDEM) has been adapted to assess the reliability of composite structures under uncertainties within the material properties and the external loadings. A Back-Propagation Neural Network approach is employed to identify the system's nonlinear structural response, which is often the case under large deformations. To exemplify, a split Hopkinson pressure bar system was employed to mimic the mechanical behavior of a... 

Reliability evaluations play a significant role in engineering applications to ensure the serviceability and safety of advanced structures such as those made of composites. Here, a dynamic reliability evaluation analysis based on the probability density evolution Method (PDEM) has been adapted to assess the reliability of composite structures under uncertainties within the material properties and the external loadings. A Back-Propagation Neural Network approach is employed to identify the system's nonlinear structural response, which is often the case under large deformations. To exemplify, a split Hopkinson pressure bar system was employed to mimic the mechanical behavior of a... 

Wearable measuring system has major effects on biomechanics of human movements especially in daily activities in order to monitor and analyze the human movements to achieve the most important kinematics parameters. In the recent decade, inertial sensors were utilized by researchers in order to developing wearable system for instrumentation of human movements. In this study, Sharif-Human Movement Instrumentation System (SHARIF-HMIS) was designed and manufactured. The system consists of inertial measurement units (IMUs), stretchable clothing and data logger. The IMU sensors are installed on the human body. The system can be used at home and also industrial environments. The main features of...