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    Hydrogel Design and Development for Osteoarthritis Treatment

    , M.Sc. Thesis Sharif University of Technology Mirshafeeyan, Mahshad (Author) ; Yaghmaei, Soheyla (Supervisor) ; Mashayekhan, Shohreh (Supervisor)
    Abstract
    "osteoarthritis" is one of the most common joint diseases. This disease has a close relationship with factors such as aging, weight gain, genetics, mechanical pressures, and severe injuries. Although the mechanism of this disease is not fully understood, inflammation is one of the main causes of its exacerbation and progression. controlling inflammation can greatly help in controlling the disease. One of the common treatment methods for osteoarthritis is intra-articular injection of hyaluronic acid and triamcinolone as anti-inflammatory drug. Hyaluronic acid is the main component of synovial fluid, with its viscosupplementation property, prevents bones from rubbing against each other in the...