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mofrad--ehsan
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Aerodynamic Design Methodology for Changing Axial Compressor Capacity
, M.Sc. Thesis Sharif University of Technology ; Ghorbanian, Kaveh (Supervisor)
Abstract
Axial compressor design is a very complex and expensive process. In general, for design and development of a new axial compressor, manufacturing companies usually intend to employ an existing and successful axial compressor as an starting point and modify and upgrade it. In this regard, dimensional scaling is a common method for derivative axial compressors. The goal of dimensional scaling is to get a different capacitywhile minimizing the development time and cost. In this thesis, theNASA eight stage transonic axial flow compressor is chosen as the base model for dimensional scaling to lower and upper size of its original dimension. The scaled compressor is analyzed with a quasi 2-D code....
Simulation of the effects of oxygen carriers and scaffold geometry on oxygen distribution and cell growth in a channeled scaffold for engineering myocardium
, Article Mathematical Biosciences ; Volume 294 , 2017 , Pages 160-171 ; 00255564 (ISSN) ; Mashayekhan, S ; Bastani, D ; Sharif University of Technology
2017
Abstract
This study proposes a mathematical model to evaluate the impact of oxygen carriers and scaffold geometry on oxygen distribution and cell growth in a 3D cardiac construct using computational fluid dynamics (CFD). Flow equations, oxygen balance equation and cell balance equation were solved using special initial and boundary conditions. The modeling results revealed that 55% increase in cardiac cell density occurred by using 6.4% perfluorocarbon oxygen carrier (PFC) compared to pure culture medium without PFC supplementation. Moreover, the effects of the scaffold geometry on cell density were examined by changing the channel numbers and the construct length. A 30% increase in the average cells...
Design of Injectable Hydrogel Scaffold based on Smart Polymer in Tissue Engineering
, M.Sc. Thesis Sharif University of Technology ; Shamloo, Amir (Supervisor)
Abstract
Nerve damage is one of the factors affecting the quality of life of patients. The nervous system does not have the ability to repair large injuries, and autologous transplantation, which is the standard treatment method for nerve injuries, is faced with a shortage of donors and a decrease in the function of the donor site. Tissue engineering hydrogels, due to their similarity to the natural tissue of the stomatal body, are a hope for the repair of nerve tissue. In this research, an injectable, minimally invasive and temperature-sensitive hydrogel based on chitosan-etaglycerophosphate-sodium hydrogen carbonate salt or trisodium phosphate salt containing aligned nanofibers made of gelatin and...
Directional migration and differentiation of neural stem cells within three-dimensional microenvironments
, Article Integrative Biology (United Kingdom) ; Volume 7, Issue 3 , Jan , 2015 , Pages 335-344 ; 17579694 (ISSN) ; Heibatollahi, M ; Mofrad, M. R. K ; Sharif University of Technology
Royal Society of Chemistry
2015
Abstract
Harnessing neural stem cells to repair neuronal damage is a promising potential treatment for neuronal diseases. To enable future therapeutic efficacy, the survival, proliferation, migration and differentiation of neural stem/progenitor cells (NPCs) should be accurately studied and optimized in in vitro platforms before transplanting these cells into the body for treatment purposes. Such studies can determine the appropriate quantities of the biochemical and biomechanical factors needed to control and optimize NPC behavior in vivo. In this study, NPCs were cultured within a microfluidic device while being encapsulated within the collagen matrix. The migration and differentiation of NPCs were...
A Ring Selection Platform for Treatment of Keratoconus
, M.Sc. Thesis Sharif University of Technology ; Asghari, Mohsen (Supervisor)
Abstract
Corneal keratoconus is one of the common eye diseases that usually occurs in the teenage years or the beginning of the third decade of life. In this disease, the cornea thins and loses its original shape and becomes conical. To treat this disease, ophthalmologists use different methods such as using glasses, contact lenses (hard and soft), corneal transplantation, and also corneal cross-linking, each of these methods has limitations, on the other hand, considering that The disease progresses and its severity increases, Ophthalmologists use corneal rings to treat this disease in more advanced stages, implanting a suitable ring in the patient's cornea both increases the strength of the...
Robust Optimization of Portfolio with Stock Options
, M.Sc. Thesis Sharif University of Technology ; Modarres Yazdi, Mohammad (Supervisor)
Abstract
In this thesis, we apply robust optimization to analyze the uncertainty of model parameters of a portfolio optimization which contains stock options. We also develop two robust counterpart models for single period and multiperiod problems. By assuming that the probability distribution of parameters is not known, their uncertainty is considered to lie within known linear intervals. Due to the existence of nonlinear relations (piecewise linear) between uncertain data (stock and option price), we present an over-conservative robust model to make the solution feasible for all parameters. However in the second model by adopting a different approach we develop a robust counterpart model with...
Effect of Cu2+ ion on biological performance of nanostructured uorapatite doped with copper
, Article Scientia Iranica ; Volume 24, Issue 6 , 2017 , Pages 2845-2855 ; 10263098 (ISSN) ; Sadrnezhaad, S. K ; Vahdati Khaki, J ; Sharif University of Technology
2017
Abstract
Nanostructured copper-doped uorapatite (Cux.Ca(10X).(PO4)6.F2) having crystallite sizes of 19, 29, and 34 nm at x = 0:9, 0.4, and 0.0, respectively, was synthesized by planetary ball milling of CaO, P2O5, CaF2, and CuO powders. Specifications of the products were determined by Fourier-transform infrared spectroscopy, eld emission scanning electron microscopy, transmission electron microscopy, and X-ray di raction analyses. In-vitro studies and Mossman's Tetrazole Test (MTT) assays were also conducted by incubating Cux.Ca(10X).(PO6).F2 powder into Kokubo's Simulated Body Fluid (SBF) and against BT-20 cell, respectively, to determine bioactivity and biocompatibility of the materials....
Mechanism of nanostructured fluorapatite formation from CaO, CaF2 and P2O5 precursors by mechanochemical synthesis
, Article Progress in Reaction Kinetics and Mechanism ; Volume 43, Issue 3-4 , 2018 , Pages 201-210 ; 14686783 (ISSN) ; Sadrnezhaad, S. K ; Vahdati Khaki, J ; Sharif University of Technology
Science Reviews 2000 Ltd
2018
Abstract
We determined the mechanism of mechanochemical synthesis of fluorapatite from CaO, CaF2 and P2O5 by characterisation of the intermediate compounds. We used atomic absorption spectroscopy, X-ray diffraction, field emission scanning electron microscopy, FTIR spectroscopy and transmission electron microscopy to find the transitional compounds. Investigation of the binary and ternary powder mixtures revealed the appearance of H3PO4, Ca(OH)2, Ca2P2O7 and CaCO3 as the intermediate compounds. At early stages of the milling, conversions of P2O5 to H3PO4 and CaO to Ca(OH)2 occurred in the wet atmosphere. Later, a combination of Ca(OH)2 and H3PO4 formed Ca2P2O7 while the unreacted CaO was converted to...
Comparison of logarithmic, elliptic, and conical helical spiral for isolation of circulating tumor cells based on inertial method
, Article Physics of Fluids ; Volume 34, Issue 9 , 2022 ; 10706631 (ISSN) ; Mozhdehbakhsh Mofrad, Y ; Safari, M ; Naseri, T ; Sharif University of Technology
American Institute of Physics Inc
2022
Abstract
Cancer is one of the most significant causes of death in the world. It has been shown that the role of circulating tumor cells (CTCs) in the early detection of cancer is crucial. Since the number of these cancerous cells in blood is very rare, the inertial microfluidic devices are one of the best candidates for the isolation of CTCs because they result in a high throughput process. Consequently, they can process a large volume of blood in a short time. Despite extensive computational and experimental studies on inertial microfluidic platforms, the impact of the curvature has not been thoroughly investigated during separation. In this paper, the feasibility of isolation of CTCs for...
Distributed Generation Planning in Deregulated Electric Industry Using Multi-objective Optimization
, M.Sc. Thesis Sharif University of Technology ; Ehsan, Mehdi (Supervisor)Methods of Clearing Reactive Power Market and Cost Allocation in Pool Structure
, M.Sc. Thesis Sharif University of Technology ; Ehsan, Mehdi (Supervisor)
Abstract
Restructuring and privatization in power system such as any industry leads to better market operation and more social welfare. Since two decade the power system in many countries have changed from monopoly to free market. In a restructured network the technical and economical aspects should be considered together. Ancillary services are needed for any power system to be operated in an optimal and secure manner. Reactive power and voltage regulation is one of the most important ancillary services in the network. this service should be supplied by its providers through a competitive market and system operator determines the optimal dispatch among different bids. The cost of purchasing reactive...
Dynamic Security Assessment in Restructured Power Systems
, Ph.D. Dissertation Sharif University of Technology ; Ehsan, Mahdi (Supervisor)
Abstract
This thesis addresses the problem of dynamic security assessment in power sys-tems with an emphasis on its application in restructured power systems and issues arising in its applications. The new electric utility environment has an immedi-ate consequence of emphasis on reliability and secure operation of power systems. This requires faster and more precise methods to assess the dynamic aspect of se-curity. On the other hand, this issue is becoming challenging when the determined dispatch might not be accommodated due to violation of the limits.This thesis addresses the problem of dynamic security assessment in power sys-tems with an emphasis on its application in restructured power systems...
Optimal Sizing and Operation of CHP Based on Stochastic Programming
, M.Sc. Thesis Sharif University of Technology ; Ehsan, Mehdi (Supervisor)
Abstract
CHP (Combined Heat and Power) generates electricity and thermal energy simultaneously from input fuel. Since it has high energy efficiency and low installation time, it is an appropriate approach in energy management of residential complexes. In this project, stochastic programming based on Monte Carlo approach is used to handle uncertainties in the optimal sizing of CHP for residential complexes. Availability of CHP, boiler and AC bus as well as the electrical and thermal load forecast errors are considered as stochastic variables. Minimizing system total cost considering the probability of each scenario obtained from the scenario reduction algorithm is the objective function. The system...
Multi Objective Distributed Generation Planning in a Flexible Environment
, Ph.D. Dissertation Sharif University of Technology ; Ehsan, Mehdi (Supervisor)
Abstract
The process of deregulation that has involved electricity many markets has introduced several new interesting research topics in power system area. This thesis addresses one of the most fascinating issues among them: the study of distributed generation both renewable and conventional integration in distribution networks. From the distribution network operator (DNO)'s point of view, it is of interest to develop a comprehensive methodology which considers various distributed generation technologies as an option for supplying the demand in distribution networks. In this thesis, the planning problem has been multi-objectively modeled. This will help the planner in decision making while knowing...
Genco's Bidding Strategy in Day-Ahead Energy Market Considering Demand Response
, M.Sc. Thesis Sharif University of Technology ; Ehsan, Mehdi (Supervisor)
Abstract
Since 1980s the electricity market has been gradually evolving from a monopoly market into a liberalized one for encouraging competition and improving efficiency. This brings the opportunity for generation companies (Gencos) to make more profits while embracing more risks of not being dispatched. Therefore, it has become a core interest for the Gencos to develop optimal bidding strategies to maximize the profits and minimize the risks while participating in such a competitive market. Error of determining day-ahead electricity price is one of the sources of the risk. Energy price has a high impact on bidding strategy optimization process. So it should be determined with low error which is not...
, M.Sc. Thesis Sharif University of Technology ; Ehsan, Mehdi (Supervisor)
Abstract
Losses are unavoidable in any parts of power systems, from generation to receiving nodes and occur in transmission and distribution networks. However, the main loss component is produced in distribution networks. Energy losses in distribution networks are about 70% of technological transport energy losses.
Energy losses in distribution networks are an important indicator for the planning and operation of the system. A fast, reliable and accurate energy loss calculation method is required for optimal operation of the distribution networks.
Energy loss depends on network's operating conditions. Loads values and loads factors are time variables; therefore, methods based on probability...
Energy losses in distribution networks are an important indicator for the planning and operation of the system. A fast, reliable and accurate energy loss calculation method is required for optimal operation of the distribution networks.
Energy loss depends on network's operating conditions. Loads values and loads factors are time variables; therefore, methods based on probability...
Security Constrained Unit Commitment With Natural Gas Transmission Delivery Constraints
, M.Sc. Thesis Sharif University of Technology ; Ehsan, Mahdi (Supervisor)
Abstract
Natural gas power plant installed in power system as rapid start unit. In the recent decades, with increasing in the number of gas generating units in the world, consideration of natural gas transmission network in optimal solution of security-constrained unit commitment (SCUC) become a non-negligible problem. The gas transmission grid constraints integrated into the scheduling of thermal units in the proposed model for minimizes power system operating cost. In a power plant transmission of natural gas to power plant is very important because congestion in natural gas pipeline increases. This model could consider natural gas storage tank in gas transmission network as decision variable....
Planning of Energy Storage Systems with the Main Goal of Managing the Output Power of Wind Farms
, M.Sc. Thesis Sharif University of Technology ; Ehsan , Mehdi (Supervisor)
Abstract
Uncertain fuel prices and also global climate changes are accompanied by some state initiatives such as renewable portfolio standards (RPS). This has caused a fast growth in the amount of renewable energy installed worldwide especially wind energy over last decades. However, the intrinsic characteristics of wind farms output power, i.e. intermittency and volatility of wind speed along with being non-dispatchable in output generation of wind turbine raises many new technical and financial challenges for power system operators and planners. Up to these issues, large level of wind power penetration causes a growing concern in wind energy curtailment issue which the wind farm’s operator may be...
Retailer’s Medium-term Planning in Distribution Network Considering Uncertainty and Competitive Enviroment
, Ph.D. Dissertation Sharif University of Technology ; Ehsan , Mehdi (Supervisor)
Abstract
Electricity retailers are one of the power market entities which act as an intermediary between the producers in the wholesale market and the consumers in the retail side. The main task of a retailer in the power market is to set contract with the consumers to supply their electricity during a pre-specified time period and to participate in the wholesale market to supply the electricity needed by its costomers. Retailer’s contract with its customers may be a simple contract with a fixed pre-determined energy price or include some more complicated feathures such as involvement of a percent of green energy or variable price and demand response contracts. Moreover, retailer can supply its...
Scheduling of Retailers Performance in Electrical Energy Markets with Energy Production;Sell in Pool Market; and Demand Response Policies
, M.Sc. Thesis Sharif University of Technology ; Ehsan, Mehdy (Supervisor)
Abstract
Recent years of capitalism bold role and the competitive environment of variant fields of our life, sparking the idea which considers the electricity (one of the most crucial human requirement) as a commodity of a competitive market to be traded between confident subscribers by easy access. Therefore, by converting the exclusive structure of electricity supply system to a competitive one, some new roles are created to fulfill the electricity generation, transmission and distribution processes. Retail is one of the new roles, defined as a power system restructuring development helper by support of electricity trading, which can be involved in different transactions according to the market...