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    A particle swarm-BFGS algorithm for nonlinear programming problems

    , Article Computers and Operations Research ; Volume 40, Issue 4 , April , 2013 , Pages 963-972 ; 03050548 (ISSN) Mohammad Nezhad, A ; Aliakbari Shandiz, R ; Eshraghniaye Jahromi, A ; Sharif University of Technology
    2013
    Abstract
    This article proposes a hybrid optimization algorithm based on a modified BFGS and particle swarm optimization to solve medium scale nonlinear programs. The hybrid algorithm integrates the modified BFGS into particle swarm optimization to solve augmented Lagrangian penalty function. In doing so, the algorithm launches into a global search over the solution space while keeping a detailed exploration into the neighborhoods. To shed light on the merit of the algorithm, we provide a test bed consisting of 30 test problems to compare our algorithm against two of its variations along with two state-of-the-art nonlinear optimization algorithms. The numerical experiments illustrate that the proposed... 

    Aggregation-Based Colorimetric Sensor for Determination of Prothioconazole Fungicide Using Colloidal Silver Nanoparticles (AgNPs)

    , M.Sc. Thesis Sharif University of Technology Jafar-Nezhad Ivrigh, Zahra (Author) ; Hormozi-Nezhad, Mohammad Reza (Supervisor)
    Abstract
    There is a growing interest in developing high-performance sensors monitoring fungicides, due to their broadly usage and their adverse effects on humans and wildlife. In the present study, a colorimetric probe has been proposed for detection of prothioconazole based on aggregation of unmodified silver nanoparticles (AgNPs). Under optimized condition, linear relationships between the concentration of prothioconazole and the absorbance ratio of A500/A395 were found over the range of 0.01 µg. mL-1 to 0.4 µg. mL-1 with Detection limit as low as 1.7 ng. mL-1. Furthermore, AgNPs color change from yellow to pink-orange in presence of prothioconazole, indicates highly sensitive naked-eye... 

    An artificial neural network meta-model for constrained simulation optimization

    , Article Journal of the Operational Research Society ; Vol. 65, issue. 8 , August , 2014 , pp. 1232-1244 ; ISSN: 01605682 Mohammad Nezhad, A ; Mahlooji, H ; Sharif University of Technology
    2014
    Abstract
    This paper presents artificial neural network (ANN) meta-models for expensive continuous simulation optimization (SO) with stochastic constraints. These meta-models are used within a sequential experimental design to approximate the objective function and the stochastic constraints. To capture the non-linear nature of the ANN, the SO problem is iteratively approximated via non-linear programming problems whose (near) optimal solutions obtain estimates of the global optima. Following the optimization step, a cutting plane-relaxation scheme is invoked to drop uninformative estimates of the global optima from the experimental design. This approximation is iterated until a terminating condition... 

    A revised particle swarm optimization based discrete Lagrange multipliers method for nonlinear programming problems

    , Article Computers and Operations Research ; Volume 38, Issue 8 , 2011 , Pages 1164-1174 ; 03050548 (ISSN) Mohammad Nezhad, A ; Mahlooji, H ; Sharif University of Technology
    2011
    Abstract
    In this paper, a new algorithm for solving constrained nonlinear programming problems is presented. The basis of our proposed algorithm is none other than the necessary and sufficient conditions that one deals within a discrete constrained local optimum in the context of the discrete Lagrange multipliers theory. We adopt a revised particle swarm optimization algorithm and extend it toward solving nonlinear programming problems with continuous decision variables. To measure the merits of our algorithm, we provide numerical experiments for several renowned benchmark problems and compare the outcome against the best results reported in the literature. The empirical assessments demonstrate that... 

    Two New Meta-Model Based Artificial Neural Network Algorithms for Constrained Simulation Optimization Problems with Stochastic Constraints

    , M.Sc. Thesis Sharif University of Technology Mohammad Nezhad, Ali (Author) ; Mahlooji, Hashem (Supervisor)
    Abstract
    Following the recent developments in the field of decision making, a considerable number of problems involved with stochastic systems can be thought of whose analysis depends on a set of intricate mathematical relations. In such cases, simulation is one of the most popular tools that can be applied toward analysis of behavior of such stochastic systems. Not only does not the simulation model rely on such intricate mathematical relations, it also enjoys the added advantage of being free of any restricting assumptions which may normally be considered in a stochastic system.To analyze such problem, one may aim at determining the best combination of input variables to optimize the system... 

    Study of Tehran Air Pollutants Dispersion with CMAQ Modeling System

    , M.Sc. Thesis Sharif University of Technology Hashemian Nezhad, Babak (Author) ; Arhami, Mohammad (Supervisor)
    Abstract
    Tehran air quality is facing a real crisis. Reports of pertinent organizations show air quality is deteriorating in recent years and unhealthy days are increasing. As a result, study and planning in order to change this trend and moving toward improving air quality is a necessity. On the other hand, in order to make proper decisions and choosing effective approaches considering cost-effective attribute and legal, temporal and budget restrictions, selecting the right tool is essential. Air quality models are the tools which in a cost saving manner and reasonable time can provide the required results for researchers, decision makers and legislators. An applicable model correspondent with urban... 

    Spectrophotometric Determination of Ametryn Herbicide in Drainage Water Based on Aggregation of Gold Nanoparticles Capped with Citrate

    , M.Sc. Thesis Sharif University of Technology Rastgar, Mortaza (Author) ; Hormozi-Nezhad, Mohammad Reza (Supervisor) ; Torkian, A (Supervisor)
    Abstract
    Due to vast use of Ametryn herbicide in agricultural and even non-agricultural activities and the possibility of contamination of carp and natural water sources by this herbicide, determination of this herbicide in surface and ground water sources is very important. Therefor introducing simple and sensitive method for determination of Ametryn is critical.
    This study demonstrate a simple and sensitive colorimetric method for the detection and determination of Ametryn based on aggregation of citrate capped AuNPs. Studied method relies upon shape and distance dependent AuNPs surface plasmon resonance. By replacing the sulfide containing Ametryn herbicide with citrate molecules on AuNPs... 

    Lagrangian relaxation heuristics for the uncapacitated single-source multi-product facility location problem

    , Article International Journal of Production Economics ; Volume 145, Issue 2 , 2013 , Pages 713-723 ; 09255273 (ISSN) Mohammad Nezhad, A ; Manzour, H ; Salhi, S ; Sharif University of Technology
    2013
    Abstract
    Facility location problem is one of the strategic logistical drivers within the supply chain which is a hard to solve optimization problem. In this study, we focus on the uncapacitated single-source multi-product production/ distribution facility location problem with the presence of set-up cost. To efficiently tackle this decision problem, two Lagrangian-based heuristics are proposed one of which incorporates integer cuts to strengthen the formulation. Local search operators are also embedded within these methods to improve the upper bounds as the search progresses. Three sets of instances with various characteristics are generated and used to evaluate the performance of the proposed... 

    Spectrofluorimetric Determination of D-penicillamine Using FITC-capped Gold Nanoparticles Via Flourescence Resonance Energy Transfer Mechanism

    , M.Sc. Thesis Sharif University of Technology Zargar, Tahereh (Author) ; Hormozi Nezhad, Mohammad Reza (Supervisor)
    Abstract
    Recently, fluorescence resonance energy transfer (FRET) based assay through employing gold nanoparticles have been developed for sensitive and selective detection of various analytes [1,2]. These are due to the extremely high extinction coefficient of Au NPs, which induces fluorescence quenching of the attached fluorophores as a result FRET ; a process which is inversely proportional to the sixth power of the distance between fluorophore and quencher [3]. Upon the addition of the analytes with much stronger affinity for Au NPs, the fluorophore molecules are detached from the surface of the Au NPs results in an increase of fluorescence intensity, which is in direct relation with... 

    Development of Ratiometric Sensors Based on Fluorescent Nanostructures for Naked Eye Detection

    , Ph.D. Dissertation Sharif University of Technology Farahmand Nejad, Mohammad Amin (Author) ; Hormozi-Nezhad, Mohammad Reza (Supervisor)
    Abstract
    In the first part of this research, we have developed a simple and effective ratiometric fluorescence sensor for selective detection of dopamine (DA) in alkaline media by simply mixing thioglycolic acid (TGA) functionalized orange fluorescent cadmium telluride (CdTe) quantum dots (QDs) with amino-functionalized blue fluorescent carbon nanodots (CDs). Under a single excitation wavelength of 365 nm, the sensor exhibits dual-emissions centered at 445 and 603 nm. The fluorescence of CdTe QDs is selectively quenched by DA, whereas the fluorescence of CDs is insensitive to the analyte. In the presence of different amounts of DA, the variations in the dual emission intensity ratios exhibit a... 

    Determination of Hydrazine and Phenylhydrazine Based on Formation of Gold Nanoparticles Stabilized with Non-ionic Surfactants

    , M.Sc. Thesis Sharif University of Technology Karami, Pari (Author) ; Hormozi Nezhad, Mohammad Reza (Supervisor)
    Abstract
    A simple and effective procedure is proposed for colorimetric detection of hydrazine and phenylhydrazine. It was found that the reduction of AuCl4- to gold nanoparticles (Au-NPs) by these compunds in the presence of Tween-20 as a stabilizing agent produced very intense surface plasmon resonance peak of Au-NPs. The plasmon absorbance of the Au-NPs allows the quantitative spectrophotometric detection of the hydrazine and phenylhydrazine. The calibration curves derived from the changes in absorbance at λ = 530 and λ = 550 nm for hydrazine and phenylhydrazine, respectively were linear with concentration of hydrazine and phenylhydrazine in the range of 1.0×10-6- 2.0×10-4 M, 5×10-6 - 4×10-4 M,... 

    Spectrophotometric Determination of D - L-Penicillamine Using Red Shift on the Surface Plasmon Resonance Band of Au Nanoparticles

    , M.Sc. Thesis Sharif University of Technology Azargun, Mohammad (Author) ; Hormozi Nezhad, Mohammad Reza (Supervisor)
    Abstract
    We report herein the development of a highly sensitive colorimetric method for detection of D- Penicillamine using citrate capped gold nano particles (Au-NPs) .This assay relies upon the distance-dependent of gold nanoparticles surface plasmonic resonance band of gold nanoparticles. By replacing the thiol-containg chelator drug, D-Penicillamine, with citrate on the gold nano particles surface, a new peak appearing at a longer wavelength intensifies and shifts further to the red from the original peak position which depends on ionic strength, D- Penicillamine and gold nanoparticles. The ratio intensities of absorbance at longer wavelength (630 nm) to original wavelength (521 nm) allow the... 

    The Interaction Study of Thio-Organophosphate Pesticides with Colloidal Silver Nanoparticles for Colorimetric Sensing Applications

    , M.Sc. Thesis Sharif University of Technology Rahimi, Sogol (Author) ; Hormozi-Nezhad, Mohammad Reza (Supervisor)
    Abstract
    Pesticides are broadly applied in croplands, glasshouses, and orchards in order to increase agricultural products and their quality. Among the variety of pesticides, organophosphorus pesticides (OPs), possessing high insecticidal activity, acute toxicity and relatively short environmental persistence, have been widely used for pest control in agriculture. However, this effect might lead to adverse health impacts or death for mammals and humans. Thus, even at trace levels, it is of great importance to develop a simple, sensitive, inexpensive and real-time detection method for monitoring the levels of pesticides in the environment, foodstuffs and biological samples. The integration of metallic... 

    Colorimetric Determination of Tizanidine and Mercury (II) Based on Aggregation and Anti-aggregation of Gold Nanoparticles

    , M.Sc. Thesis Sharif University of Technology Yahyazadeh, Ehsan (Author) ; Hormozi Nezhad, Mohammad Reza (Supervisor)
    Abstract
    In the first section of this research, we have developed a simple and rapid colorimetric method for determination of tizanidine using citrate capped gold nanoparticles. Under optimal conditions, the AuNPs easily aggregate upon addition of tizanidine and the solution color changes from red to gray. This color change was followed using a UV-Vis spectrophotometer. The detection limit was calculated to be 0.48 µM. The method was successfully applied for determination of tizanidine in Spalex© tablets. In the last section, the anti-aggregation effect of Hg(II) on the tizanidine-AuNPs system was utilized with the aim of developing a colorimetric method for detection of Hg(II). Addition of... 

    Colorimetric Sensor Array Design for Classification and Detection of Nanoparticles and Some Biomolecules

    , Ph.D. Dissertation Sharif University of Technology Ghasemi, Forough (Author) ; Hormozi Nezhad, Mohammad Reza (Supervisor)
    Abstract
    In the first part of this research, we reported a liquid sensor array for detection and classification of biological thiols, based on aggregation of gold nanoparticles (AuNPs) with different coatings as sensor elements. Thiol mediated aggregation of AuNPs was visualized via UV–vis spectra. The spectral changes, as a consequence of aggregation of AuNPs, made a unique pattern of spectra for each analyte and allowed for the selective detection and discrimination of the biological molecules. HCA and PCA analysis demonstrated the discrimination of various thiols of different concentrations (i.e. 10–800 mmol L-1 for cysteine, 200–700 mmol L-1 for both glutathione and glutathione disulfide).... 

    Development of Nano-QSARs as Predictive Tools for Nanomaterials’ Cytotoxicity

    , Ph.D. Dissertation Sharif University of Technology Bigdeli, Arafeh (Author) ; Hormozi Nezhad, Mohammad Reza (Supervisor)
    Abstract
    The increasing role of nanotechnology in our every-day-life, has aroused global concern regarding their hazardous potential, resulting in a demand for parallel risk assessment. Quatitative structure-activity relationships enable researches to use unique properties of nanoparticles as predictors for their toxicity or any other biological response. Extracting rational correlations between physicochemical properties of nanoparticles and their biological response, not only reveals the way that nanoparticles behave upon entering into biological media, but also leads to the design of safer and efficient nanoparticles for various applications of interest. This PhD dissertation presents QSAR tools... 

    Design of an Optoelectronic Tongue Based on Anti-Aggregation of Gold Nanoparticles for Detection and Classification of Heavy Metal Ions

    , M.Sc. Thesis Sharif University of Technology Najafzadeh, Fatemeh (Author) ; Hormozi-Nezhad, Mohammad Reza (Supervisor)
    Abstract
    The first report of anti-aggregation-based sensor arrays is presented. The strategy is based on the competitive interaction of citrate-capped gold nanoparticles (AuNPs) and heavy metal ions (i.e., Hg(II), Ag(I), Fe(III), and Pb (II)) with three aggregation reagents (i.e., cysteine, melamine, and arginine). In the presence of aggregation reagent,the color and UV–vis spectra of AuNPs are changed indicating the aggregation ofAuNPs. Addition of the aggregation reagents which are firstly treated with the ions, causes AuNPs turn from the aggregation to the dispersion state. The anti-aggregation capability of ions towards various aggregation reagents is different because of distinct stability... 

    Multicolorimetric Sensor Array Based on Silver Metallization of Gold Nanorods for Discriminating Dopaminergic Agents

    , M.Sc. Thesis Sharif University of Technology Koohsar, Reza (Author) ; Hormozi Nezhad, Mohammad Reza (Supervisor)
    Abstract
    Dopaminergic agents are compounds that modulate dopamine-related activity in the brain and peripheral nerves within the pathways on both sides of the blood-brain barrier. Atypical levels of them can precipitate a multitude of neurological disorders, whose timely diagnosis signifies not only stopping the advancement of the illness but also surmounting it. A silver metallized gold nanorod (AuNRs) conditional sensor array, designed to detect dopaminergic agents for assessing nervous system disorders, yielded significant results in simultaneous detection and discrimination of Benserazide (Benz), Levodopa (L-DOPA), and Carbidopa (Carb). The array was composed of two different concentrations of... 

    Visual recognition of tryptophan enantiomers using chiral self assemblies of quantum dots

    , Article ACS Applied Nano Materials ; 2021 ; 25740970 (ISSN) Fahimi Kashani, N ; Jafar Nezhad Ivrigh, Z ; Bigdeli, A ; Hormozi Nezhad, M.R ; Sharif University of Technology
    American Chemical Society  2021
    Abstract
    Discrimination of chiral targets is generally achieved with chiral nanomaterials. However, the limited number of intrinsic chiral nanostructures as well as their complex synthesis procedure has led to the production of chirality-induced nanomaterials as alternatives. Chirality can be induced in nanomaterials by either chirality transfer or the formation of chiral assemblies. Using the latter approach, in this work, we have provided chiral supramolecular assemblies of CdTe quantum dots (QDs) from achiral starting materials. CTAB-QD assemblies showed chiroptical activities, and their orange emission in combination with the blue emission of carbon dots was utilized as a ratiometric chiral... 

    Visual recognition of tryptophan enantiomers using chiral self assemblies of quantum DOTS

    , Article ACS Applied Nano Materials ; Volume 5, Issue 1 , 2022 , Pages 1460-1471 ; 25740970 (ISSN) Fahimi-Kashani, N ; Jafar Nezhad Ivrigh, Z ; Bigdeli, A ; Hormozi Nezhad, M. R ; Sharif University of Technology
    American Chemical Society  2022
    Abstract
    Discrimination of chiral targets is generally achieved with chiral nanomaterials. However, the limited number of intrinsic chiral nanostructures as well as their complex synthesis procedure has led to the production of chirality-induced nanomaterials as alternatives. Chirality can be induced in nanomaterials by either chirality transfer or the formation of chiral assemblies. Using the latter approach, in this work, we have provided chiral supramolecular assemblies of CdTe quantum dots (QDs) from achiral starting materials. CTAB-QD assemblies showed chiroptical activities, and their orange emission in combination with the blue emission of carbon dots was utilized as a ratiometric chiral...