Sharif Digital Repository

Developing antibacterial biodegradable Mg alloys is of paramount importance to prevent infection and inflammation during the healing process. In this regard, the Mg-2Ag alloy is proposed as a suitable candidate with appropriate biocompatibility as well as antibacterial activity. However, its rapid degradation rate limits its clinical application. To tackle this problem, the hydrothermal coating technique was employed to synthesize a barrier coating to enhance the degradability of the Mg-2Ag alloy using distilled water as the reagent. Field emission scanning electron microscopy (FESEM) micrographs and X-ray diffraction (XRD) patterns showed that a hydroxide coating was formed on the studied... 

Biodegradable magnesium implants possess excellent mechanical properties and biocompatibility, which make them suitable candidates to be employed as temporary structures for the bone regeneration purposes. However, there are still important challenges which limit their extensive use in biomedical applications, where the most important ones include implant-associated infection, rapid degradation rate and the need for improved mechanical properties. Silver, which is a strong antimicrobial agent, has been extensively used for improving the mentioned challenges in biodegradable Mg alloys either as alloying element or incorporation in the protective coating. Ag addition has been reported to have... 

3D porous PLA-graphite composite scaffolds are recently introduced as promising candidates in tissue engineering practices owing to their significantly enhanced mechanical strength in comparison with pure PLA. However, they mainly suffer from low degradation rate as well as undesirable hydrophobic surface. In this regard and to address such challenges, Mg particles, as one of the lightest metallic fillers, were added to PLA-graphite scaffolds via the fused deposition modeling (FDM) technique. The obtained results indicated that introduction of 1 wt% Mg inhibited polymeric chain mobility of PLA, and hence, increased the glass transition temperature. Also, Mg particles behaved as nucleating... 

Developing a uniform polymer-based composite filament is a critical factor for a successful 3D printing process. In this regard, a novel technique for the fabrication of PLA-graphite filament with the potential to be applied to other PLA-based composite filaments was proposed and compared to the solvent casting method. This modified mixing technique involves partial dissolution of the PLA pellets surface by dichloromethane (DCM), which creates a sticky surface for the strong adhesion of reinforcement powders. The manufactured composite filament by this method exhibited excellent structural features, while the solvent casting method yielded a heterogeneous filament with a non-uniform diameter... 

The employment of tissue engineering scaffolds in the reconstruction of the damaged bone tissues has shown remarkable promise since they significantly facilitate the healing process. Fabrication of highly porous biocompatible scaffolds with sufficient mechanical strength is still challenging. In this regard, polymers have been widely utilized to construct three-dimensional (3D) porous scaffolds due to their excellent processability and biocompatibility. However, insufficient mechanical strength and inappropriate degradation rate of the monophasic polymer scaffolds in the bone regeneration process, as the main challenges, limit their extensive clinical application. The incorporation of... 

Biodegradable Mg-Ag alloys are promising implants for bone regeneration owing to their ability to decrease inflammation and infection after implantation by the presence of Ag. However, their bioperformance requires further enhancement. In this regard, the effects of 1 wt % Y addition and solid solution heat treatment (T4) on microstructure, biocorrosion behavior, mechanical properties and biological features of a cast Mg-2Ag alloy were studied. Corrosion tests indicated the remarkable role of T4 treatment in promoting corrosion resistance by increasing microstructure homogeneity, reduction of defects and volume fraction of secondary phases as well as eliminating the dendritic microstructure... 

Biodegradable magnesium (Mg) alloys exhibit great potential for use as temporary structures in tissue engineering applications. Such degradable implants require no secondary surgery for their removal. In addition, their comparable mechanical properties with the human bone, together with excellent biocompatibility, make them a suitable candidate for fracture treatments. Nevertheless, some challenges remain. Fast degradation of the Mg-based alloys in physiological environments leads to a loss of the mechanical support that is needed for complete tissue healing and also to the accumulation of hydrogen gas bubbles at the interface of the implant and tissue. Among different methods used to... 

Polylactic acid (PLA) is considered as a great option to be employed as 3D porous scaffold in hard tissue engineering applications owing to its excellent biocompatibility and processability. However, relatively weak mechanical properties and inappropriate biodegradability limit its extensive usage. In order to overcome the mentioned challenges, micrometric magnesium particles were incorporated into the PLA matrix by the fused deposition modeling (FDM) technique. The effects of various Mg contents (i.e., 2, 4, 6, 8 and 10 wt%) on the structural, thermal, rheological, mechanical, wettability, degradability characteristics and cellular behavior of the 3D porous PLA-Mg composite scaffolds were... 

Coating is an effective approach to address the high corrosion rate of biodegradable Mg alloys, as their main challenge toward their extensive use. In this regard, it was tried to control the degradation process of an Mg-4Zn alloy by Ca addition, equal channel angular pressing (ECAP), and hydrothermal coating. The obtained results indicated that excellent grain refinement induced by Ca incorporation and ECAP simultaneously, improved both mechanical strength and corrosion resistance of the Mg-based substrate. The achieved grain refinement resulted in a thicker, more compact and integrated coating, where the ECAP-processed Mg-4Zn-0.5Ca alloy exhibited the best coating quality with no... 

The original article contained a mistake in Equation 1. The corrected Equation 1 is shown below: MX+Cx+Kx=f.The original article has been updated © Springer Nature B.V. 2022  

In this study, a general 3D distributed modeling of Trolling-Mode AFM (TR-AFM) as a nanorobot is presented to analyze the 2D manipulation process of a spherical cell. To this aim, the analysis is categorized into 3 sections. In the first section, 6 deformations of TR-AFM are taken into account, and the standard model of the system is obtained. Moreover, the system is simulated in ANSYS Workbench. The results of modal and transient analyses of the system from both analytical and software methods reveal high agreement, which confirms the accuracy of the presented analytical model. In the second section, by utilizing the 3D derived model, displacement of a spherical yeast single cell (W303)... 

The anatase phase of titania was stabilised with physically modifying particulate sol-gel process. Two major parameters, peptisation temperature and drying temperature, were identified which were responsible for retarding the anatase to rutile phase transformation, crystal growth and packing of primary particles. The critical nucleus size of transformation was controlled by natural (at 25 °C) and artificial (at 50 and 70 °C) peptisation techniques. Moreover, sintering of primary particles was controlled by cool (at 0 and 5 °C) and normal (at 25 °C) drying techniques. Fourier transform infrared spectroscopy (FT-IR) analysis confirmed that a full conversion of titanium isopropoxide is obtained... 

Flow through the pores of granular materials has many instances in practice. Therefore, it is interesting to realize how some parameters, such as the shape of the particles affect the passing flow. Following the recent mathematical theory proposed by the authors, this paper deals with the issue of how tortuosity and permeability are influenced by the particle shape. Comparison of the results with the experimental data reveals the competency of the theory in predicting the impact of particle geometry  

For the present article, a pulsating heat pipe (PHP) is fabricated and tested experimentally by bending a copper tube. The effects of working fluid, heat input, charging ratio, inclination angle, magnets location, and ferrofluid (magnetic nanofluid) volumetric concentration have been investigated on the thermal performance of this PHP. Experimental results show that using ferrofluid as a working fluid improves the thermal performance of the PHP significantly. Moreover, applying a magnetic field on a ferrofluidic PHP reduces its thermal resistance. By changing the inclination angle of the PHP from vertical mode to angles close to the horizontal mode, the present PHP has a constant and... 

In this article, the control of an electrohydrodynamic 3D printer is studied. The proposed controller has a hybrid piecewise linear feedback form which is designed based on a hybrid model of the printer. The hybrid model is obtained via a gray box identification process whose structure is proposed utilizing the results of the finite element simulation of the printer within the COMSOL Multiphysics software. The asymptotic stability of the hybrid control combined with a hybrid observer is proven using the Lyapunov theory. In addition, the obtained control is applied to the finite element model of the printer to check its performance which shows the success of the controlled system in tracking... 

Nanostructured TiO2-Al2O3 films and powders were prepared by a straightforward aqueous particulate sol-gel route. Titanium (IV) isopropoxide and aluminum chloride were used as precursors, and hydroxypropyl cellulose was used as a polymeric fugitive agent in order to increase the porosity. The effect of Al:Ti molar ratio was studied on the crystallization behavior of the products. X-ray diffraction (XRD) revealed that the powders crystallized at 800°C, containing anatase-TiO2, rutile-TiO2 and cubic-Al2O3 phases. Furthermore, it was found that Al2O3 retarded the anatase to rutile transformation. Transmission electron microscope (TEM) image showed that one of the smallest crystallite sizes was... 

Analyzing the features of the chromosomes can be very useful for diagnosis of many genetic disorders or prediction of the possible abnormalities that may occur in the future generations. For this purpose, karyotype is often used which to make it, there is necessary to identify each one of the 24 chromosomes from the microscopic images. Definition and extraction of the morphological and band pattern based features for each chromosome is the first step to identify them. An important class of the morphological features is the location of the chromosome's centromere. Thus, centromere localization is an initial step in designing an automatic karyotyping system. In this paper, a novel algorithm... 

The aim of this study was to investigate the applicability of acoustic emission (AE) technique to evaluate delamination crack in glass/epoxy composite laminates under quasi-static and fatigue loading. To this aim, double cantilever beam specimens were subjected to mode I quasi-static and fatigue loading conditions and the generated AE signals were recorded during the tests. By analyzing the mechanical and AE results, an analytical correlation between the AE energy with the released strain energy and the crack growth was established. It was found that there is a 3rd degree polynomial correlation between the crack growth and the cumulative AE energy. Using this correlation the delamination... 

In this paper, a new analytical method is presented that can be used to determine the behavior of particular steel beam-to-column extended end plate connection in linear and nonlinear regions. A common means of forming a rigid joint between a universal beam and column is to weld an end plate to the beam end and then to bolt it to the column. A physically based analytical method that can predict the behavior of bolted and extended end plate eave connections, using the connection dimensions as input, is presented. This article demonstrates an analytical procedure for the establishment of elastic and plastic parts of the M-χ curve of this form of connection. An analytical method is proposed for...