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    Combinational therapy of lithium and human neural stem cells in rat spinal cord contusion model

    , Article Journal of Cellular Physiology ; Volume 234, Issue 11 , 2019 , Pages 20742-20754 ; 00219541 (ISSN) Mohammadshirazi, A ; Sadrosadat, H ; Jaberi, R ; Zareikheirabadi, M ; Mirsadeghi, S ; Naghdabadi, Z ; Ghaneezabadi, M ; Fardmanesh, M ; Baharvand, H ; Kiani, S ; Sharif University of Technology
    Wiley-Liss Inc  2019
    Abstract
    A large number of treatment approaches have been used for spinal cord injury improvement, a medically incurable disorder, and subsequently stem cell transplantation appears to be a promising strategy. The main objective of this study is to ascertain whether combinational therapy of human neural stem cells (hNSCs) together with lithium chloride improves cell survival, proliferation, and differentiation in a rat spinal contusion model, or not. Contusive spinal cord injury was implemented on Wistar male rats. Experimental groups comprised of: control, hNSCs transplanted, lithium chloride (Li), and hNSCs and lithium chloride (hNSCs + Li). In every experimental group, locomotor activity score and... 

    Intelligent semi-active vibration control of eleven degrees of freedom suspension system using magnetorheological dampers

    , Article Journal of Mechanical Science and Technology ; Volume 26, Issue 2 , 2012 , Pages 323-334 ; 1738494X (ISSN) Zareh, S. H ; Sarrafan, A ; Khayyat, A. A. A ; Zabihollah, A ; Sharif University of Technology
    2012
    Abstract
    A novel intelligent semi-active control system for an eleven degrees of freedom passenger car's suspension system using magnetorheological (MR) damper with neuro-fuzzy (NF) control strategy to enhance desired suspension performance is proposed. In comparison with earlier studies, an improvement in problem modeling is made. The proposed method consists of two parts: a fuzzy control strategy to establish an efficient controller to improve ride comfort and road handling (RCH) and an inverse mapping model to estimate the force needed for a semi-active damper. The fuzzy logic rules are extracted based on Sugeno inference engine. The inverse mapping model is based on an artificial neural network... 

    Performance and exhaust emission characteristics of a spark ignition engine operated with gasoline and CNG blend

    , Article Proceedings of the Spring Technical Conference of the ASME Internal Combustion Engine Division ; 2012 , Pages 179-187 ; 15296598 (ISSN) ; 9780791844663 (ISBN) Dashti, M ; Hamidi, A. A ; Mozafari, A. A ; Sharif University of Technology
    2012
    Abstract
    Using CNG as an additive for gasoline is a proper choice due to higher octane number of CNG enriched gasoline with respect to that of gasoline. As a result, it is possible to use gasoline with lower octane number in the engine. This would also mean the increase of compression ratio in SI engines resulting in higher performance and lower gasoline consumption. Over the years, the use of simulation codes to model the thermodynamic cycle of an internal combustion engine have developed tools for more efficient engine designs and fuel combustion. In this study, a thermodynamic cycle simulation of a conventional four-stroke spark-ignition engine has been developed. The model is used to study the... 

    A comparative study of the performance of a SI engine fuelled by natural gas as alternative fuel by thermodynamic simulation

    , Article 2009 ASME Internal Combustion Engine Division Fall Technical Conference, ICEF 2009, Lucerne, 27 September 2009 through 30 September 2009 ; 2009 , Pages 49-57 ; 9780791843635 (ISBN) Dashti, M ; Hamidi, A. A ; Mozafari, A. A ; Sharif University of Technology
    American Society of Mechanical Engineers (ASME)  2009
    Abstract
    With the declining energy resources and increase of pollutant emissions, a great deal of efforts has been focused on the development of alternatives for fossil fuels. One of the promising alternative fuels to gasoline in the internal combustion engine is natural gas [1-5]. The application of natural gas in current internal combustion engines is realistic due to its many benefits. The higher thermal efficiency due to the higher octane value and lower exhaust emissions including CO2 as a result of the lower carbon to hydrogen ratio of the fuel are the two important feature of using CNG as an alternative fuel. It is well known that computer simulation codes are valuable economically as a cost... 

    Analytical and experimental analyses of nonlinear vibrations in a rotary inverted pendulum

    , Article Nonlinear Dynamics ; Volume 107, Issue 3 , 2022 , Pages 1887-1902 ; 0924090X (ISSN) Dolatabad, M.R ; Pasharavesh, A ; Khayyat, A. A. A ; Sharif University of Technology
    Springer Science and Business Media B.V  2022
    Abstract
    Gaining insight into possible vibratory responses of dynamical systems around their stable equilibria is an essential step, which must be taken before their design and application. The results of such a study can significantly help prevent instability in closed-loop stabilized systems by avoiding the excitation of the system in the neighborhood of its resonance. This paper investigates nonlinear oscillations of a rotary inverted pendulum (RIP) with a full-state feedback controller. Lagrange’s equations are employed to derive an accurate 2-DoF mathematical model, whose parameter values are extracted by both the measurement and 3D modeling of the real system components. Although the governing... 

    A suction-controlled ring device to measure the coefficient of lateral soil pressure in unsaturated soils

    , Article Geotechnical Testing Journal ; Volume 44, Issue 1 , 2020 Pirjalili, A ; Garakani, A. A ; Golshani, A ; Mirzaii, A ; Sharif University of Technology
    ASTM International  2020
    Abstract
    A suction-controlled ring device has been developed to continuously measure the coefficient of lateral soil pressure in deformable unsaturated soil samples from the at-rest to the active condition under application of increasing vertical pressure and controlled matric suction. The device incorporates a thin aluminum specimen ring equipped with horizontal strain gages for recording the lateral soil strains. In addition, a sensor recording water volume changes is utilized to continuously monitor the degree of saturation of the soil sample during tests. The matric suction within the soil texture is controlled using the axis translation technique. In order to verify the performance of the ring... 

    Gum tragacanth gels as a new supporting matrix for immobilization of whole-cell

    , Article Iranian Journal of Chemistry and Chemical Engineering ; Volume 24, Issue 4 , 2005 , Pages 1-7 ; 10219986 (ISSN) Otady, M ; Vaziri, A ; Seifkordi, A. A ; Kheirolomoom, A ; Sharif University of Technology
    2005
    Abstract
    We introduce a new smooth, non-toxic, biocompatible method for cross-linking of gum tragacanth (GT), a polysaccharide of natural origin, in order to serve as a new supporting matrix for immobilization systems. The modified gum is used as a matrix for the catalysis of the conversion of benzyl penicillin to 6-aminopenicillanic acid (6-APA) by means of Escherichia coli ATCC11105 with penicillin G acylase (PGA) activity. The results show that GT beads can not only serve as a proper matrix for immobilization, but show enhanced hydrolysis rate and stability compared to other immobilization systems used for this reaction. This signifies the potential of GT as a biocompatible matrix for... 

    True Class-E Design For Inductive Coupling Wireless Power Transfer Applications

    , Article 30th International Conference on Electrical Engineering, ICEE 2022, 17 May 2022 through 19 May 2022 ; 2022 , Pages 864-868 ; 9781665480871 (ISBN) Haeri, A. A. R ; Safarian, A ; Fotowat Ahmady, A ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2022
    Abstract
    The Class-E power amplifier has been widely studied and formulated in the literature. Although the majority of reported inductive coupling wireless power transfer (WPT) systems use a class-E power amplifier for driving the primary coil, still there is a lack of a comprehensive study on class-E circuit dedicated to WPT, providing a set of closed form design equations for proper class-E operation. This paper presents the required design equations needed to design a 'true' class-E circuit for WPT applications. Equations for the series-tuned secondary coil WPT system are presented, as well as two different design procedures for the parallel-tuned secondary coil. The derived equations have been... 

    Crashworthiness determination of side doors and B pillar of a vehicle subjected to pole side impact

    , Article Applied Mechanics and Materials ; Vol. 663, issue , 2014 , p. 552-556 Lilehkoohi, A. H ; Faieza, A. A ; Sahari, B. B ; Nuraini, A. A ; Halali, M ; Sharif University of Technology
    2014
    Abstract
    Pole Side Impact Tes is one out of three crash tests described by Euro NCAP standard for star rating of a vehicle and is required for assessing the Adult Occupant Protection. In this paper the goal is to determine the crashworthiness of side doors and B pillar in a Pole Side Impact Test based on Euro New Car Assessment Program (Euro-NCAP) using computer and simulation method. In this matter, a vehicle model has been prepared and meshed using Hypermesh and CATIA. The velocity of 29 km/h has been assigned to the vehicle which was on top of a cart while the pole has been assigned as a rigid static object based on Euro NCAP requirements specifically. Results show that different amounts of energy... 

    Investigation of Thickness Influences On Energy Absorption For Side Doors And B Pillar In Euro NCAP Pole Side Impact Test

    , Article Applied Mechanics and Materials ; Vol. 663, issue , Oct , 2014 , p. 585-589 Lilehkoohi, A. H ; Faieza, A. A ; Sahari, B. B ; Nuraini, A. A ; Halali, M ; Sharif University of Technology
    2014
    Abstract
    To assess a car under the Euro New Car Assessment Program (Euro-NCAP), Adult Occupant Protection is one out of three parameters which need to be calculated with a weight factor of 50% while the other parameters, Child Occupant Protection and Pedestrian Occupant Protection, have a weight factor of 20%. The Pole Side Impact Test, beside two other tests, Side and Front Impact, is also required to calculate the Adult Occupant Protection. It shows how important the Pole Side Impact Test is and what an effective role it has in the car rating assessment. In this paper, the objective is to evaluate the effect of thickness on the energy absorbed by the side doors and the B pillar and its... 

    Crashworthiness determination for front and rear doors and B pillar subjected to side impact crash by a mobile deformable barrier

    , Article Advanced Science Letters ; Volume 19, Issue 2 , 2013 , Pages 392-395 ; 19366612 (ISSN) Lilehkoohi, A. H ; Faieza, A. A ; Sahari, B. B ; Nuraini, A. A ; Halali, M ; Sharif University of Technology
    2013
    Abstract
    In Euro NCAP standard, adult protection is one of the most important rating scores with 50% weight factor while child protection and pedestrian protection are accounted into consideration with 20% weight factor. For adult protection testing, three tests are required to perform: (1) side impact, (2) pole impact, (3) front impact. In the side impact test, dummy's head, chest, shoulder, thorax, ribs, abdomen, pelvic and femur must be studied to evaluate the rating score. Crashworthiness of a car during side impact can describe the score rated for that car. In this paper the goal is to determine the crashworthiness of side doors and B-pillar in side impact crash est by simulation using LS DYNA... 

    Effect of material and thickness of side doors and B pillar on crashworthiness in euro NCAP side impact crash test

    , Article Advanced Science Letters ; Volume 19, Issue 2 , 2013 , Pages 420-424 ; 19366612 (ISSN) Lilehkoohi, A. H ; Faieza, A. A ; Sahari, B. B ; Nuraini, A. A ; Halali, M ; Sharif University of Technology
    2013
    Abstract
    In side impact test which is one out of three tests of Euro NCAP standard, front and rear doors and B pillar are most absorbance parts among vehicle body parts. Passengers are highly in danger while side crash, because of the distance between passenger's head and vehicle body. In this paper effect of material and thickness of doors and B-pillar and their absorbed energy during crash and improvement of its crashworthiness with respect to light weight design are studied using LS DYNA solver. The objective of this paper is to propose a material for doors and B-pillar with a specified thickness to achieve maximum absorbed energy and minimum weight. The shape of the doors and B-pillar remains... 

    Effect of recycle gas composition of the performance of Fischer-Tropsch catalyst

    , Article Petroleum Science and Technology ; Volume 28, Issue 5 , 2010 , Pages 458-468 ; 10916466 (ISSN) Rohani, A. A ; Khorashe, F ; Safekordi, A. A ; Tavassoli, A ; Sharif University of Technology
    2010
    Abstract
    In this study, the influence of CO2 and CH4 on the performance and selectivity of Co-Ru/Al2O3 catalyst is investigated by injection of these gases (0-20 vol.% of feed) to the feed stream. The effect of temperature and feed flow rate are also inspected. The results show that low amounts of CO2 in the feed stream do not change the catalyst activity, but increasing the amount of CO2 (more than 10 vol.%), causes the CO conversion to decrease and the selectivity of heavy components to increase. Methane acts as an inert gas and does not affect the catalyst performance. Increasing feed flow rate has a negative effect on both CO conversion and heavy component selectivity. By raising the temperature,... 

    Simulation and estimation of normal dispersion phenomenon in an acentric organic crystal (NPP) by the quantum photonic approach

    , Article Modelling and Simulation in Materials Science and Engineering ; Volume 15, Issue 8 , 2007 , Pages 869-878 ; 09650393 (ISSN) Kaatuzian, H ; Zarch, A. W ; Oskouei, A. A ; Amjadi, A ; Sharif University of Technology
    2007
    Abstract
    In this paper, we present a nano-quantum photonic approach for the calculation of normal dispersion phenomena in organic crystals such as N-(4-nitrophenyl)-L-prolinol(NPP). We assume that a laser beam consists of a flow of energetic particles that interact with the distorted π-electron system. We approximate the distorted π-electron cloud by an ellipse to simplify calculations. By the precise analysis of photon interaction with the π-electron system of benzene ring in the NPP crystal, we obtain the refractive index in any wavelength by Monte Carlo simulation. The maximum error between our simulation results and the measurement data is 0.058, which is agreeable. © 2007 IOP Publishing Ltd  

    Water electrolyte transport through corrugated carbon nanopores [electronic resource]

    , Article Physical Review E - Statistical, Nonlinear, and Soft Matter Physics ; Volume 90, Issue 1, July 2014, Article number 012304 Moghimi Kheirabadi . A ; Moosavi. A
    Abstract
    We investigate the effect of wall roughness on water electrolyte transport characteristics at different temperatures through carbon nanotubes by using nonequilibrium molecular dynamics simulations. Our results reveal that shearing stress and the nominal viscosity increase with ion concentration in corrugated carbon nanotubes (CNTs), in contrast to cases in smooth CNTs. Also, the temperature increase leads to the reduction of shearing stress and the nominal viscosity at moderate degrees of wall roughness. At high degrees of wall roughness, the temperature increase will enhance radial movements and increases resistance against fluid motion. As the fluid velocity increases, the particles do not... 

    Catalytic wet peroxide oxidation of phenol in a new two-impinging-jets reactor

    , Article Industrial and Engineering Chemistry Research ; Volume 48, Issue 23 , 2009 , Pages 10619-10626 ; 08885885 (ISSN) Dehkordi, A. M ; Ebrahimi, A. A ; Sharif University of Technology
    2009
    Abstract
    The catalytic wet peroxide oxidation (CWPO) of phenol with activated carbon (AC) as the catalyst has been successfully tested in a novel type of two-impinging-jets reactor (TIJR). The TIJR is characterized by a high-intensity reaction chamber, which is separated by a perforated plate from other parts of the reactor. The perforated plate was used as a filter to keep the catalyst particles within the reaction chamber. The influences of various operating and design parameters such as jet Reynolds number, feed flow rate, internozzle distance, and the jet diameter on the performance capability of the TIJR were investigated. As a result of the impinging process, turbulence, complex trajectory of... 

    Flow visualization of internal waves and wakes of a streamlined body in a stratified fluid

    , Article Journal of Applied Fluid Mechanics ; Volume 9, Issue 2 , 2016 , Pages 635-641 ; 17353572 (ISSN) Bidokhti, A. A ; Bidokhti, A. A ; Sharif University of Technology
    Isfahan University of Technology  2016
    Abstract
    The wake and internal waves of a moving three dimensional (3D) airfoil body in a stratified fluid has been investigated in a large stratified tank with a finite depth using movies of shadowgraphs of the flow fields. Typical Reynolds and Froude numbers of the flow varied between 103 and 104, and 0.3 and 2 respectively. The flows are generated often by towing the body in a uniformly stratified flow, while limited cases are carried out with body stationary and the channel was in recirculating mode. For some experiments the density profile had a stepped like shape. The wake flow is often consisted of internal waves including random and coherent ones. Distortion of density fields was also... 

    Investigation on the wear properties of Ti/TiC/TiN composite coatings prepared by powder cored wires through TIG method at nitrogen atmosphere on titanium substrate

    , Article Materials Research ; Volume 22, Issue 2 , 2019 ; 15161439 (ISSN) Kokabi, A. H ; Allahyari, A. A ; Sharif University of Technology
    Universidade Federal de Sao Carlos  2019
    Abstract
    In this present study, Tungsten Inert Gas (TIG) welding and powder filled cored wires with nitrogen shielding gas were utilized to produce TiC and TiN surface composite coatings on the titanium (Ti) sheet substrate. The TIG procedure was done at same welding parameters for all of prepared samples. Phase analysis and microstructures were done by X-ray Diffraction (XRD), Energy-Dispersive X-ray Spectroscopy (EDS), Optical Microscopy (OM) and Scanning Electron Microscopy (SEM). The obtained results from XRD and EDS demonstrated that the presence of crystalline phases of TiC, TiN and Ti. SEM and OM exhibited formation of the spherical and dendritic TiC particles in a martensitic matrix and also,... 

    Ultimate strength analysis of jacket type offshore platforms due to wave, current and wind loading

    , Article Proceedings of the International Conference on Offshore Mechanics and Arctic Engineering - OMAE, 15 June 2008 through 20 June 2008, Berlin ; Volume 1 , 2008 , Pages 779-786 ; 9780791848234 (ISBN) Mirzadeh Niasar, J ; Aghakouchak, A. A ; Samadani, S ; Aghakouchak, A
    2008
    Abstract
    As the result of safety factors considered in load and resistant values for the design of new offshore platforms, a higher resistance compared to the 100 year return period environmental loading, is achieved in the structure. This type of design is usually performed using linear methods of structural analysis. In this case the structure practically has a high reserve capacity which is disregarded in the design phase but may be considered in special cases. One of these important cases is when an existing structure is assessed and evaluated after elapse of its structural life. In this case using the platforms reserve capacity, through a non-linear analysis such as push-over, would be logical... 

    Possible role for growth hormone in suppressing acylated ghrelin and hunger ratings during and after intermittent exercise of different intensities in obese individuals

    , Article Acta Medica Iranica ; Vol. 52, Issue. 1 , 2014 , pp. 29-37 ; ISSN: 1735-9694 Gholipour, M ; Kordi, M. R ; Taghikhani, M ; Ravasi, A. A ; Gaeini, A. A ; Tabrizi, A ; Sharif University of Technology
    2014
    Abstract
    Body weight is influenced by both food intake and energy expenditure. Acylated ghrelin enhances appetite, and its circulating level is suppressed by Growth Hormone. Data on the acylated ghrelin responses to exercise of different intensities in obese individuals are currently not available. This study examined the effects of an intermittent exercise protocol on acylated ghrelin levels and hunger ratings in obese people. Nine inactive male ran on the treadmill at 0900 with progressive intensities of 50, 60, 70, and 80% of VO2max for 10, 10, 5, and 2 min respectively. Blood samples were collected before the exercise at 0845 (-15 min as the resting values), after each workload (10, 23, 31, and...