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Metal-organic frameworks-based nanomaterials for drug delivery
, Article Materials ; Volume 14, Issue 13 , 2021 ; 19961944 (ISSN) ; Rabiee, N ; Mozafari, M ; Mostafavi, E ; Sharif University of Technology
MDPI AG
2021
Abstract
The composition and topology of metal-organic frameworks (MOFs) are exceptionally tailorable; moreover, they are extremely porous and represent an excellent Brunauer–Emmett–Teller (BET) surface area (≈3000–6000 m2·g−1). Nanoscale MOFs (NMOFs), as cargo nanocarriers, have increasingly attracted the attention of scientists and biotechnologists during the past decade, in parallel with the evolution in the use of porous nanomaterials in biomedicine. Compared to other nanoparticle-based delivery systems, such as porous nanosilica, nanomicelles, and dendrimer-encapsulated nanoparticles, NMOFs are more flexible, have a higher biodegradability potential, and can be more easily functionalized to meet...
Fourier photoacoustic microscope improved resolution on single-pixel imaging
, Article Applied Optics ; Volume 61, Issue 5 , 2022 , Pages 1219-1228 ; 1559128X (ISSN) ; Amjadian, M ; Kavehvash, Z ; Shabany, M ; Sharif University of Technology
The Optical Society
2022
Abstract
A new single-pixel Fourier photoacoustic microscopy (PAM), to the best of our knowledge, is proposed to improve the resolution and region of interest (ROI) of an acquired image. In the previous structure of single-pixel Fourier PAM, called spatially invariant resolution PAM (SIR-PAM), the lateral resolution and ROI are limited by the digital micromirror device (DMD) pixel size and the number of pixels. This limitation is overcome here through illuminating fixed angle interfering plane waves, changing the fringe frequency via varying the frequency of the laser source. Given that the fringe sinusoidal patterns here can be produced by two mirrors, the DMD usage can be omitted. In this way, the...
Effect of financial and technical uncertainty on distribution network reconstruction project selection
, Article IET Conference Publications ; Volume 2013, Issue 615 CP , 2013 ; 9781849197328 (ISBN) ; Eini, B. J ; Mehrabi, A ; Naghdi, M ; Sharif University of Technology
2013
Abstract
Distribution companies are pressurized into investing in many projects for ensuring customer satisfaction and increasing their profitability. There are a lot of feasible projects that may help companies to improve their services, but resources for accomplishing them are limited. Therefore, financial subjects are crucially important for related decision making and budget allocation is a bone of contention between different departments of companies. Project net present value (NPV), which depends on investment, expected annual profit, interest rate and inflation rate, is realistic criterion of project economic value. Interest rate and inflation rate are not predefined coefficients....
The non-significant benefit of BCG vaccination for the treatment of iranian patients with type 1 diabetes up to 48 weeks: a controversial result
, Article Medical Journal of the Islamic Republic of Iran ; Volume 35, Issue 1 , 2021 , Pages 1-5 ; 10161430 (ISSN) ; Zarei, P ; Shakerian, B ; Babaei, M ; Mostafavi, A ; Modaressi, M ; Sharif University of Technology
Iran University of Medical Sciences
2021
Abstract
Background: There has been considerable interest in target immunotherapy in patients with diabetes. This study was designed to identify the effect of BCG vaccination in the treatment of Iranian patients with longstanding diabetes mellitus type 1. Methods: After approval of the cross-sectional study protocol by the ethics committee under number IRCT2017042919940N2, a total of 19 Iranian volunteers with diabetes mellitus type 1 completed this 48-month study. These patients received three 0.1 ml intradermal injections of BCG vaccination in weeks 0, 4 and 24. The serum level of glucose, HgbA1C and c-peptide was measured before and serially after the interventions. Insulin requirements were...
The Analysis of Total Productive Maintenance Based on Computerized Maintenance Management System
, M.Sc. Thesis Sharif University of Technology ; mostafavi, mostafa (Supervisor)
Abstract
The main purpose of this thesis is to analyze the total productive maintenance based on computerized maintenance management system. At first, a detailed study on total productive maintenance is performed and then the requirements of this maintenance strategy are specified. Also, a computerized maintenance management system is defined which can help total productive maintenance to reach to its requirements. Finally, a conceptual model and entity-relationship model for computerized maintenance management system data base has been created
Feasibility Study of Producing Active Pharmaceutical Ingredient from Conceptual Process to Mass Production-Case Study
, M.Sc. Thesis Sharif University of Technology ; Mostafavi, Mostafa (Supervisor)
Abstract
The main aim of this thesis is to develop the technical knowledge of designing and making active ingredients of domestically produced drugs, decreasing the costs, independency in producing these products, and checking outflow of currency. It also aims to reduce the financial challenges of patients who have to pay huge amounts for such drugs. Conducting research in the field of reverse engineering and using its definition, and attempt in made to get knowledge into the stages of product development process, to determine the technical standards associated with each stage, to recognize how knowledge is shared during this process, and to present some methods of establishing the infrastructure...
The Analysis of Knowledge Management, Dimensions and Implementation Methods-Case study: Sardsaz Khodro Ind. Co
, M.Sc. Thesis Sharif University of Technology ; Mostafavi, Mostafa (Supervisor)
Abstract
Today, organizations are surrounded by basic and continuous changes such as declining organizational resources, reduction of the production cycles, and the need for rapid adaption. Those organizations remain competitive while maintaining their productivity, that have following characteristics: accurately plan and assess their knowledge resources, create and absorb beneficial knowledge, store and organize their knowledge, disseminate knowledge to needed areas, and use knowledge in practice and decision making, to improve their products/services as well as their performance. Therefore, the human capital has been considered as knowledge owners and the most important organizational resource, on...
Analyzing the Healthcare Wastes and Feasibility Study of Related Items (Plastics)
, M.Sc. Thesis Sharif University of Technology ; Mostafavi, Mostafa (Supervisor)
Abstract
Increasing population and competition for producing various productions and also more consumption in recent decades, result in producing more wastes. Therefore effective and continuous waste management is essential for monitoring the process (from the wastes generation source to the waste disposal) and establishing the efficient strategies to reduce wastes. One of the major sources of waste generation is hospitals that cause lots of environmental problem unless they are managed properly.Recycling is an important element of waste management that can reduce costs by innovative and proper management. The purpose of this research is identification of recyclable plastic items and estimates the...
Analyzing Cost Engineering Along With Presenting A Model To Reduce Cost Of industrial Products
, M.Sc. Thesis Sharif University of Technology ; Mostafavi, Mostafa (Supervisor)
Abstract
Lack of financial sources for production and performing projects has been an effective issue in all governmental and non-governmental organizations. So, using a structure with capability of detecting and forecasting all expenses and costs, and being able to convert the mass of data into useful and instrumental reports for managerial decision such as estimating total cost, selecting the syntax of production and etc is obvious for recourse management of every organization. Among the various components of the cost engineering system, cost management system by recording and allocating cost is an important issue in efficiency of every cost engineering system.In this thesis, Automotive Industrial...
Feasibility Study of Manufacturing of Disposable Plant Containers
,
M.Sc. Thesis
Sharif University of Technology
;
Mostafavi, Mostafa
(Supervisor)
Abstract
Although laws vary in the competitive business world of today and the changing supply and demand parameters show that the process of delivering new products to market is very important.Most organizations today have found that spending more than ever on trusting in traditional competitive levers such as quality, cost reduction and differentiation in selling more products and services are not enough to be successful in market, instead notions such as speed, flexibility andagility can have a significant trend toward offering new products and services. There aresome good reasons for knew that organizations need new ways to develop their new products to survival, compete with its competitors and...
Research to Provide Iranian Customer Satisfaction Index Model in Industry, Case Study: Iran Khodro Co., Golrang Co. and Kaleh Co
, M.Sc. Thesis Sharif University of Technology ; Mostafavi, Mostafa (Supervisor)
Abstract
In recent decades many countries have attempted to measure and formulate customer satisfaction index (CSI), as an important factor in micro and macro-economic level. In developed country CSI has the same value of GNP. Customer Satisfaction Index model actually represents the relationship between primary factors of satisfaction and satisfaction results in the macro level for a country and includes all business aspects. In many countries, industrial companies have a wide range of products and providing Customer Satisfaction Index model for this aspect which can be a base of presenting national customer satisfaction index model. Accordingly, the main goal of this study is providing an Iranian...
Assessment of Effectiveness of the “Physical Asset Management Model” in Productivity of Maintenance System, Using ERP
, M.Sc. Thesis Sharif University of Technology ; Mostafavi, Mostafa (Supervisor)
Abstract
People in the organization who are influential, opinion leaders, decision-makers and approvers need to be incorporated into the entire Strategic Planning process at some levels .The Management of these Stakeholders involves identifying their organizational roles and their disposition towards and understanding of Strategic Planning, then to work with them throughout the process to improve or maintain their opinion of the value of Strategic Planning through continuous updating and addressing of their issues, concerns and questions. Physical asset practitioners apply the physical asset management framework and policies to ensure the performance and output potential of physical assets through...
Feasibility Study of Fuel Cell Production with Sustainable Environment Approach
, M.Sc. Thesis Sharif University of Technology ; Mostafavi, Mostafa (Supervisor)
Abstract
So far, many activities have been done in regarding to decrease vehicles' pollution in the international level that the electric vehicles manufacture has been emphasized in recent years. According to these issues and need to decrease air and environment pollution, the use of fuel cell as a source of power generation can have a specific effect on decreasing this pollution. In our country, according to high statistics of manufacturing and offering vehicle particularly the vehicles with high pollution, there is a need to invest in the field of creating renewable (clean) energy production systems. Regarding to decrease environment pollution and according to the importance of fuel cell's...
Analysis of Dimensions, Objective and Implementation of Knowledge Management in Production Institutes
, M.Sc. Thesis Sharif University of Technology ; Mostafavi, Mostafa (Supervisor)
Abstract
The increasing significance and deployment of knowledge management(KM) is the main reason for selecting the topic of this research. This research tries to analyse the dimensions and KM implementation methods in press section of maintenance department in Saipa company. This study has a qualitative approach and the method is based on a case study. Data has been collected by questionnaires. Two questionnares have been provided in this research and distributed among different staff of press section in maintenance department. The concept of knowledge management maturity is applied and the goal of first questionnaire is based on this concept. The level of KM maturity is assessed via this...
Spatial Swarm Robotics and Decentralized and Scalable Control Mission
, M.Sc. Thesis Sharif University of Technology ; Sayyaadi, Hassan (Supervisor)
Abstract
Swarm robots have been interested by researchers in recent years. The most important reason of this attention is the abilities of these systems for doing some works that a single robot can’t do them alone. The goal of this article is formation control of a group of flying robots with nonholonomic dynamics. The agents are considered helicopters with dimension, mass and moment of inertia. Firstly, the dynamics equation of helicopter will be derived as for Newton-Euler method. Next, input-output equations will be derived and controller will be designed by using sliding mode method. Main rotor and tail rotor thrusts, roll and pitch torques of main rotor are the system inputs. The control method...
Cost Engineering: Objectives, Dimensions and to Study Cost Engineering Methods and Models with an Approach to a Proper Model in Manufacturing Activities-case Study: Mapna Locomotive Engineering and Manufacturing Company
, M.Sc. Thesis Sharif University of Technology ; Mostafavi, Mostafa (Supervisor)
Abstract
In the process of industrial and economic development and in the competitive environment in the world, reducing the cost of industrial products is an important factor for more customers' satisfaction, more revenue acquisition, and stability and success in the business. Cost engineering is the area of engineering practice concerned with the application of scientific principles and techniques to problems of cost estimating, cost control, business planning, management science, profitability analysis, project management, planning and scheduling. In this research through the studying the structures and models of cost engineering, in addition to consider this dimensions of cost engineering, the...
Developing Fragility Curves for Seismic Isolated Reinforced Concrete Structures
, M.Sc. Thesis Sharif University of Technology ; Bakhshi, Ali (Supervisor)
Abstract
Nowadays, base isolation technique is widely used in the old and new structures, so it is necessary to assess the seismic performance of base-isolated buildings probabilistically, it is also essential to assess their performance during near-source versus far-field earthquakes.
Developing the fragility curves is useful probabilistic method for the seismic assessment of structures. These curves define the probability of exceedance of different damage states for a given level of seismic intensity parameter. Former investigations has been done to assess the seismic behavior of base isolation systems consider base isolated highway bridge piers.
In this thesis fragility curves are derived...
Developing the fragility curves is useful probabilistic method for the seismic assessment of structures. These curves define the probability of exceedance of different damage states for a given level of seismic intensity parameter. Former investigations has been done to assess the seismic behavior of base isolation systems consider base isolated highway bridge piers.
In this thesis fragility curves are derived...
Analysis of Effectiveness of Implementing Knowledge Management in Origanizational Productivity-tavanir Corporation
, M.Sc. Thesis Sharif University of Technology ; Mostafavi, Mostafa (Supervisor)
Abstract
In the present era, data and its impressive access is considered to be one of the key elements in development, in a way that all social, economic process, severly require information. Today knowledge is the most important tool in competition of present and future markets. Implementation of knowledge management should be accomplished in a step by step process. One of the main goals of implementing knowledge management is increasing of the organizational productivity. This study has a qualitative approach and the method is based on a case study. Data has been collected by questionnaires. Due to this fact, knowledge management should be applied according to organizational productivity. Among...
Condition Monitoring of Water Pipelines by Using Acoustic Method a Study of Leak Detection in ABFA
, M.Sc. Thesis Sharif University of Technology ; Mostafavi, Mostafa (Supervisor)
Abstract
Water is crucial to human being. We use water for a wide variety of uses daily. However, leakage has caused substantial water loss to our precious processed water. The major contributor to non-revenue water in Iran is pipeline leakages. The water industry in the nation has invested in equipment to detect and localize leaks in water distribution systems. One of the equipment mentioned is acoustic-based. The principle of acoustic is that whenever a leak is present in a pipeline, noise is generated and will travel along the pipeline. The acoustic leak detection method is then derived by calculating the distance traveled by this noise generated by the leak. Different equipment based on acoustic...
Service Level Agreement Templates and Guides for Implementing, using eTOM
, M.Sc. Thesis Sharif University of Technology ; Mostafavi, Mostafa (Supervisor)
Abstract
Nowadays, in communication industry, specially data network, in which service quality is a serious parameter, request for making connection with appropriate quality (Proportionate to demands) and necessity of clarification of obligations of service providers and customers, as well as customer awareness of submitted materials and offering various services with different qualities & costs, led service providers, specially IP based networks, to make agreements with their customers, entitled service Level Agreement (SLA). The SLA specifies the service type, mutual obligations, related parameters, measuring methods, violation threshold, penalties and loss compensation. Whereas, applying...