Sharif Digital Repository

Nerve damage is one of the factors affecting the quality of life of patients. The nervous system does not have the ability to repair large injuries, and autologous transplantation, which is the standard treatment method for nerve injuries, is faced with a shortage of donors and a decrease in the function of the donor site. Tissue engineering hydrogels, due to their similarity to the natural tissue of the stomatal body, are a hope for the repair of nerve tissue. In this research, an injectable, minimally invasive and temperature-sensitive hydrogel based on chitosan-etaglycerophosphate-sodium hydrogen carbonate salt or trisodium phosphate salt containing aligned nanofibers made of gelatin and... 

In this thesis, we studied the oscillation of neutrino flavors and the measurement of mixing parameters through the detection of cosmic neutrinos at neutrino telescopes. Most of the astrophysical explosions predict the emission of neutrino flux and kilometer-scale detectors are under construction for the observation of these neutrinos. Detection of astrophysical neutrinos opens a new window to understand the neutrino properties and also the properties of astrophysical sources.In this thesis first we review the phenomenology of neutrino flavor oscillation and characteristics of neutrino mass matrix. By introducing a new class of invariants (under general transformation of lepton fields bases)... 

Excitability is one of the most important characteristics of a neuron. In 1948, Hodgkin identified three different types of excitability of neurons. Excitability an all of its types can be observed in Hodgkin-Huxley model of neuronal dynamics (H-H model) as a four-dimensional system of differential equations and in at least two dimensional reductions of H-H type models. By applying the theory of dynamical systems (e.g. bifurcation theory), one can give a mathematical definition of excitability.Excitability of the neuron is equivalent to that the neuronal model is near a bifurcation through which the state of the system approaches to a stable limit cycle. In this thesis, a two-dimensional... 

Neutrino flavor oscillations are clear evidence of massive neutrinos. It has been for more than a decade that neutrino physics became one of active topics in the field of particle physics and various experiments started studying the flavor oscillation of neutrinos. Unfortunately, experiments studying the flavor oscillations are only sensitive to the mass square difference, and they are incapable of providing more information about the absolute mass scale of neutrinos. Additionally, sterile neutrinos having non-standard interactions are under vast investigations and studies. Determination of neutrino masses and their effective number is among the most challenging problems by which... 

Axial compressor design is a very complex and expensive process. In general, for design and development of a new axial compressor, manufacturing companies usually intend to employ an existing and successful axial compressor as an starting point and modify and upgrade it. In this regard, dimensional scaling is a common method for derivative axial compressors. The goal of dimensional scaling is to get a different capacitywhile minimizing the development time and cost. In this thesis, theNASA eight stage transonic axial flow compressor is chosen as the base model for dimensional scaling to lower and upper size of its original dimension. The scaled compressor is analyzed with a quasi 2-D code.... 

Corneal keratoconus is one of the common eye diseases that usually occurs in the teenage years or the beginning of the third decade of life. In this disease, the cornea thins and loses its original shape and becomes conical. To treat this disease, ophthalmologists use different methods such as using glasses, contact lenses (hard and soft), corneal transplantation, and also corneal cross-linking, each of these methods has limitations, on the other hand, considering that The disease progresses and its severity increases, Ophthalmologists use corneal rings to treat this disease in more advanced stages, implanting a suitable ring in the patient's cornea both increases the strength of the... 

In this thesis, we apply robust optimization to analyze the uncertainty of model parameters of a portfolio optimization which contains stock options. We also develop two robust counterpart models for single period and multiperiod problems. By assuming that the probability distribution of parameters is not known, their uncertainty is considered to lie within known linear intervals. Due to the existence of nonlinear relations (piecewise linear) between uncertain data (stock and option price), we present an over-conservative robust model to make the solution feasible for all parameters. However in the second model by adopting a different approach we develop a robust counterpart model with... 

Alpha amylase enzyme is one of the most important enzymes used in a wide range of industries. The enzyme is used in industries such as detergents, food, pharmaceuticals, paper making and textile. Various national and international articles have been published on this enzyme that focused on specific targets. Despite the extensive studies carried out in this area inside the country, there is still no industrial production of alpha amylase and other enzymes in our country. In the view of the fundamental problem of the lack of industrialization of these studies, in addition to the lack of a riskier investor, it seems that there is a lack of industrial vision in these studies.In this study, the... 

In this study graphene and graphene adsorbent for the Co2+ ion were created from sodium phenoxide and calcium phenoxide, respectively, using the chemical vapor deposition method, and their chemical, physical, and morphological properties were investigated using FT-IR, UV, XRD, Raman, TEM, FE-SEM, and XPS. The results suggest that the optimum reaction condition for synthesizing mono-layer and multi-layer graphene is the 750 °C temperature for 30 min. The Co2+ adsorbing properties of the synthesized graphene adsorbent from calcium phenoxide was investigated. The investigation of solvation properties suggests insolubility above 650 °C and the kinetic data suggest the rapidness of the Co2+...