Sharif Digital Repository

Based on the importance of DNA/RNA binding proteins in different cellular processes, finding binding sites of them play crucial role in many applications, like designing drug/vaccine, designing protein, and cancer control. Many studies target this issue and try to improve the prediction accuracy with three strategies: complex neural-network structures, various types of inputs, and ML methods to extract input features. But due to the growing volume of sequences, these methods face serious processing challenges. So, this paper presents KDeep, based on CNN-LSTM and the primary form of DNA/RNA sequences as input. As the key feature improving the prediction accuracy, we propose a new encoding... 

Speech synthesis and its applications have been very attractive recently. The main purpose of this technique is to produce a speech signal with natural characteristics of human speech like prosody and emotion. Among all existing methods for speech synthesis, statistical parametric speech synthesis methods are more promising because ofhigher flexibility in comparison to other methods. One of the applications of speech synthesis is speech to speech translation. In these systems, the generated voice in target language should have the same characteristics as the input voice in source language. The main purpose of this research is to review and evaluate the cross lingual speaker adaptation... 

Surface piercing propellers are particular type of supercavitating propellers that are commonly used for High-speed vessels. Most studies on this type of propellers has been investigating the hydrodynamic forces. But in recent years with increase in SPPs diameter used in vessels, structural analysis of this type of propellers is considered. For this purpose, studies on the stresses exerted on the propeller structures under load is done with the help of Hydro elastic methods. In this type of analysis, structura of propeller is intended to be flexible and Displacements under pressure checked and Tensions resulting from it are studied.
The present Thesis using ANSYS software to analyze a... 

Pricing plays an important and essential role in the profit and income of companies. The importance of pricing is not only related to its role in the company's profitability, but it also changes the customer's understanding and loyalty towards the company and can create the company's reputation or destroy it. Determining the right price will increase product sales and increase customer loyalty and create a competitive advantage for the company. One of the most important and influential variables in product pricing is the amount of demand. The main challenge of companies for product pricing is the uncertainty in their demand. In order to deal with this problem, data-driven pricing is used.... 

The increasing demand for autonomous vehicles and reliable communication protocols and hardware interfaces, such as CAN bus and USB, underscores the necessity for stable clock sources that maintain a low temperature coefficient (TC) over wide temperature ranges. This demand is particularly emphasized in applications such as wearables, network sensors, downhole devices, WSNs, and IoT, where long-lasting battery life and frequency-stable clock sources over a broad temperature range (e.g. -20 °C to 100 °C) are crucial. Traditionally, variations in frequency caused by temperature have been mitigated by employing off-chip components like crystals or ceramic based oscillators, but this approach... 

Autonomous vehicles, as an integral part of intelligent transportation systems, will play a significant role in the future of transportation services. These vehicles have a high potential to improve road traffic capacity and the efficiency of transportation systems. One type of autonomous vehicle is the connected and autonomous vehicle (CAV), which can communicate with each other, roadside units, traffic control signals, and other infrastructures or devices. This study investigates the impact of autonomous vehicles and connected and autonomous vehicles on the traffic flow of the Tehran-Karaj freeway and vice versa, under various penetration rates and in a mixed traffic environment. In this... 

In the current situation and considering the economic conditions, entrepreneurship and self-employment are important factors of business growth. To prepare people in this field, there is a need for effective training that can motivate people. Identifying the effective methods and different dimensions of the entrepreneurship education framework that can lead to setting up a successful program for training people and facilitate the way to achieve the goal of education is one of the important goals of this research. By studying the literature from 2010 onwards, this research systematically examined 96 articles and tried to improve the framework of entrepreneurship education that was stated in... 

Research on the characteristics of the near field earthquakes has been very popular in recent years due to the considerable damages they have caused to the structures located within the vicinity of seismic sources. The incapability of response spectra for structural damage assessment has been revealed through recent investigations. The recorded data show that the near field earthquakes are often accompanied by a large energy pulse in the beginning of the records caused by the so-called directivity phenomenon. That has encouraged many researchers to study the possibility of using the velocity pulse of these records to evaluate the imposed seismic demands on structures. Thus, investigating the... 

Considering the widespread applications of amides, synthesis of these compounds is of great importance. The one pot oxidative addition of amines to aldehydes is one of the most simple and appealing approaches to synthesis amides. With the aim of developing a mild and convenient approach towards preparation of amides, numerous methods have been reported for this important process over the past few decades. These improvements have been mostly related to the optimization of reaction conditions and the use of more challenging substrates including diverse derivatives of aldehydes, and also design a novel and effective catalytic systems. Due to the various advantages of supported heterogeneous... 

Financial and monetary markets are appropriate areas of applying Chaos Theory. Firstly, current theories of financial and monetary economics state that economic and financial variables such as exchange rates and stock prices are stochastic, so forecasting them is almost impossible. Secondly, if we find the hidden ordered and deterministic trends, we can achieve considerable profits. In this piece of research, we evaluate different methods and tests of detecting chaos in financial time series, and choose the most applicable methods to test financial markets’ indices. The main three indices of Tehran Stock Exchange, including Price, Finance and Industry indices, are examined. A sample of the... 

Considering the widespread applications of α-aminonitriles, their synthesis is of great importance. The Strecker reaction represents a direct and appealing approach for the preparation of α-aminonitriles. With the aim of developing a mild and convenient approach towards the construction of α-aminonitriles, numerous methods have been reported for this important process over the past few decades. These have been mostly related to the optimization of reaction conditions and the use of more challenging substrates including ketimines and ketiminium salts and design of novel and effective catalytic systems. Due to the various advantages of supported heterogeneous catalysts and in our aim to... 

Entrance of air to close water conduits occurs in many ways. This phenomenon makes displeasing effects on water transport structures. Two-phase flows in closed conduits are studied experimentally, numerically and theoretically. Even after decades, due to the complexity of the subject, these studies still require development and reformation. Numerical and theoretical two-phase models are often limited to a special regime of flow."Volume Of Fluid"(VOF) is a model for non-mixing two-phase flows. "Fluent" software uses this model in this field of flows. Volume of fluid is used successfully in some problems like dam break or rising bubbles. Main disadvantage of this model is distribution of the... 

In this project, polymer nanocomposites containing graphene oxide were prepared and used for adsorption of several cationic and anionic dyes. In most cases, these nanocomposites were prepared as three-dimentional polymer networks which contain graphene oxide. Nanocomposites with direct grafting of polymer chains onto the surface of graphene oxide were also prepared. Graphene oxide is an oxidized carbonaceous material with unique properties. This material has high surface area, good mechanical strength and various functional groups. Polymeric compounds with different functional groups, structures and properties can be prepared and used. By preparing composites of graphene oxide and polymers,... 

Common fracture treatments include open reduction and intramedullary nailing technology. However, these methods have disadvantages such as intraoperative X-ray radiation, delayed union or nonunion and postoperative rotation. Robots provide a novel solution to the aforementioned problems while having new challenges. The robotic system used in the study by providing more precise motion and exerting higher amount of forces makes the operation procedure more straightforward. In a normal operation 300-400 N of extension force would be needed which is fully provided by the surgen which leads to physical his/her (khastegi), by using the robotic system however, this force is simply provided without...