Sharif Digital Repository

In this project, the equilibrium structure of clamped-free silicon nano-beams is investigated using molecular dynamics (MD) simulations. Four main interatomic potentials for silicon nanostructures, i.e. Tersoff, MEAM, Stillinger-Weber and EDIP, are implemented in the current study. Using aforementioned potentials, the structural stability of Si nano-beams are studied and effects of thickness, width, length, size, lattice direction, facets of cross section, and temperature on the equilibrium structure of nano-beams are investigated. The conducted simulations demonstrate that equilibrium structure of nano-beam is completely dependent on the type of atomic potential used for modeling.... 

Submerging of the Micro-beam of the AFM is indispensible in case of imaging bio-samples. (Bio-samples are unstable in non-aquos environment.), so hydrodynamical interaction of liquid and beam (viscous and meniscus forces) will result into quality factor decrease. This will cause image resolution decrement as well as damage to the sample because of large tip-sample forces during imaging of the bio-samples. The proposed method “Trolling mode AFM” keeps the micro-beam of the AFM out of the liquid, by adding a nano-needle to the end of the AFM tip. This would lead to resolve the aforementioned problems. Modeling of a part of the operation of this mechanism was done in this thesis, in order to... 

Micro-robotics is one of the currently emerging technologies which has attracted attentions for its probable applications in different fields including biotechnology, diagnosis and treatment in medical engineering as well as general studies in micro-scale science and engineering. Magnetic micro-robotics is considered as the most promising group, primarily due to the biocompatibility of magnetic fields and advances in electronic circuits to produce and control such fields. One critical point in utilizing these robots is their high density in comparison with the working fluid and their tendency to sink. In this thesis, a method to fabricate buoyant magnetic robots has been proposed based on... 

Today, the need to access very small environments is felt in various medical, industrial, biological and military fields. Due to their small size, microrobots have the ability to perform tasks that would be very difficult to do on a larger scale, but this ability of microrobots makes feeding and controlling them challenging. There are several methods for providing power and control of microrobots, which include their internal or external stimulation, among which the magnetic stimulation method is used in this research, which does not cause damage to body tissues.In this thesis, an electromagnetic system with nine cylindrical coils is used to control the three-dimensional movement of magnetic... 

Endoscopy is a medical operation in which a camera is sent into the patient's body and the physician starts taking pictures at specified times. In the traditional endoscopic procedure, a camera is sent into the body by a guiding wire. This can cause severe pain to the patient. In the newer method, a camera is mounted on a small capsule and the patient swallows the capsule. Then the camera inside the capsule starts taking photos and sends them out. This procedure, in addition to being painless, allows the physician to access the innermost parts of the body or the digestive tract.In capsule endoscopy, unlike the older method, one has to find the position and orientation of the capsule at any... 

Nowadays, endoscopic capsules are an interesting technique due to their ability to minimize patient discomfort and provide access to all parts of the gastrointestinal tract. However, they lack some capabilities of traditional methods, such as performing biopsies. An essential requirement for performing a biopsy of a specific part of the gastrointestinal tract is capsule control; in addition, localization information is required for closed-loop control. The goal of this research is the localization and control of a capsule with a biopsy module. For this purpose, an endoscopic capsule using the concept of a magnetic spring was introduced, which had different magnets so its localization and... 

Minimally invasive procedures are diagnostic or therapeutic methods that cause minimal injuries and side effects for patients. PCI is a common minimally invasive procedure for diagnosis and curing of cardiovascular disorders. In this procedure, the surgeon can have access to the cardiac vessels by a flexible instrument. However, motion control of this instrument inside the patient's body relies on surgeon's skills and in some cases, is time consuming so that the toxic effects of radiation on patient and surgical team increases. Magnetic flexible instruments are suggested to address this problem. Nevertheless, motion control of the flexible instrument inside the body still has many challenges... 

In this research, we aim to study and simulate how nanoparticels translocate through cell membrane. For this purpose, at first a gold nanoparticle is selected as the drug carrier. The partial charges of the ligands are calculated using quantum mechanics based on HF technique with 6-31Gd basis set. To have a realistic shape for nano drug, number and arrangement of ligands are determined based on optimization. After all atom simulations and comparison of results such as diffusion coefficient with experiments, a coarse-grained model of these drugs is created and put inside solvent beside a membrane. The cytoplasmic membrane includes more than 60 types of phospholipids like animal membranes.... 

Nanopositioning is technology of positioning & manipulation of Nano-scale object. This technology can be considered as one of the fundamental necessities in Nano & Micro research and fabrication and made lots of unbelievable advancement in researches and technologies. There are lots of mechanical systems designed for large scale positioning with sub millimeter resolution, but when it’s come to Nano scale, the range of access should be limited to some micrometer. Also in Nano-scale motion some difficulties like backlash, stick-slip and friction is phenomenon. For increasing the workspace using coarse and fine positioning systems may be an appropriate method. In this method a fine positioning... 

Currently, the use of robots and microrobots in medical applications has significantly increased due to their extensive and unique capabilities. One such application involves the utilization of magnetic continuum robots controlled by an external magnetic field in minimally invasive surgeries. This research focuses on discussing methods for effectively controlling magnetic-continuum robots and applying external magnetic fields. Two primary methods for applying the external magnetic field are explored: the use of electromagnetic coils and permanent magnets. Based on these methods, systems for applying the field and controlling the magnetic continuum robot have been constructed and... 

Minimally invasive surgery is highly valued mainly due to the reduction of the patient’s recovery period. Catheters are among the most important tools in minimally invasive surgeries. Catheter is a flexible tool that has the ability to pass through difficult paths. In common localization methods, fluoroscopy is used to determine the position of the catheter’s tip. One main disadvantage of this method is that it is very dangerous for therapists who are exposed to X-ray radiation for long periods of time. A magnetic catheter is created by adding a magnet to the end of the catheter. The possibility of guiding magnetic catheter by an external magnetic field, controlling the applied force and... 

Being harmless to living tissues makes magnetic robots very promising for medical applications. Furthermore, since these robots are driven by external magnetic fields, no actuators are needed to be placed on the robots, enabling them to come in very small dimensions if necessary. Motion control of small magnetic particles paves the way for future applications, such as deliberate drug-delivery, sampling, and lowinvasive surgeries.The goal of this research is to design and construct a platform for generating desired magnetic fields in order to control the motion of magnetic robots in threedimensional space. In order to do so, a system of eight electromagnetic coils with iron cores was built.... 

Atomic force microscopy (AFM), as an indispensable tool for nanoscale characterization, has major drawback for operation in a liquid environment arising from the large hydrodynamic drag on the vibrating cantilever. The newly introduced “Trolling Mode” (TR-Mode) AFM resolves this complication utilizing a specialized nanoneedle cantilever that keeps the cantilever outside of the liquid. Herein, a mechanical model with a lumped mass was developed to capture the dynamics of such cantilever with a nanoneedle tip. This new developed model was applied to investigate the effects of the needle – liquid interface on the performance of the AFM, including the imaging capability in liquid. Also... 

One of the most significant aerial vehicles which has been subject of study of so many engineers and students is quadrotor or quadcopter, which is a cross sectional configuration of motors and propellers. This aerial robot is controlled through slight differences between the angular velocities of the four motors, and robot dynamics is completely nonlinear, thus sophisticated control algorithms are needed. The aim of this project consists of design, fabrication and control of a quadrotor capable of stable hovering. First, some preliminary decisions about general charachteristics of the robot were made. According to these decisions, other mechanical parts were designed and fabricated. Then,...