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    Zwitterion-functionalized MIL-125-NH2-based thin-film nanocomposite forward osmosis membranes: towards improved performance for salt rejection and heavy metal removal

    , Article New Journal of Chemistry ; Volume 46, Issue 31 , 2022 , Pages 15205-15218 ; 11440546 (ISSN) Bayrami, A ; Bagherzadeh, M ; Navi, H ; Nikkhoo, M ; Amini, M ; Sharif University of Technology
    Royal Society of Chemistry  2022
    Abstract
    In the current study, thin-film nanocomposite membranes (TFN-Mx) based on a zwitterion-functionalized metal-organic framework (MOF) have been developed for the forward osmosis (FO) salt-water separation process. The active polyamide layer was formed through the interfacial polymerization of the m-phenylenediamine aqueous phase (with or without the presence of MIL-125-NH-CC-Cys) and the trimesoyl chloride organic phase. In comparison with the results from the surface of the unmodified membrane, a nanofiller-incorporated TFN-M0.10 membrane represents a smoother and more wettable surface that collaborates synergically to enhance the membrane antifouling ability. Among the examined membranes,... 

    A poroelastic finite element model to describe the time-dependent response of lumbar intervertebral disc

    , Article Journal of Medical Imaging and Health Informatics ; Volume 1, Issue 3 , 2011 , Pages 246-251 ; 21567018 (ISSN) Nikkhoo, M ; Haghpanahi, M ; Wang, J. L ; Parnianpour, M ; Sharif University of Technology
    2011
    Abstract
    Investigation of the relationship between different types of mechanical loading and the failure of the intervertebral disc requires a well-defined finite element model. The objective of this paper was to develop and validate a nonlinear axisymmetric poroelastic finite element model of intervertebral disc and show its capability for studying the time-dependent response. After presenting the poroelastic model of intervertebral disc, the results of prolonged (short-term and long-term creep tests) and cyclic loading were compared with in vivo and in vitro experimental data. The trends predicted by FE model agreed well with measured experimental data and showed its validity for dynamic analysis.... 

    An axisymmetric poroelastic model for description of the short-term and long-term creep behavior of L4-L5 intervertebral disc

    , Article 2011 1st Middle East Conference on Biomedical Engineering, MECBME 2011, Sharjah, 21 February 2011 through 24 February 2011 ; 2011 , Pages 308-311 ; 9781424470006 (ISBN) Nikkhoo, M ; Haghpanahi, M ; Parnianpour, M ; Wang, J. L ; Sharif University of Technology
    2011
    Abstract
    Understanding the relationship between different kinds of mechanical loading and the failure of the intervertebral disc is difficult to study in vivo and in vitro. Through finite element studies some of these issues may be overcome enabling more detailed assessment of the biomechanical behavior of the intervertebral disc. The objective of this paper is to develop a nonlinear axisymmetric poroelastic finite element model of intervertebral disc and show its capability for studying the time-dependent response of disc. After comparison of the response of different models in quasi-static analysis, the poroelastic model of intervertebral disc is presented and the results of a short-term and... 

    Dynamic responses of intervertebral disc during static creep and dynamic cyclic loading: A parametric Poroelastic finite element analysis

    , Article Biomedical Engineering - Applications, Basis and Communications ; Volume 25, Issue 1 , 2013 ; 10162372 (ISSN) Nikkhoo, M ; Haghpanahi, M ; Parnianpour, M ; Wang, J. L ; Sharif University of Technology
    2013
    Abstract
    Low back pain is a common reason for activity limitation in people younger than 45 years old, and was proved to be associated with heavy physical works, repetitive lifting, impact, stationary work postures and vibrations. The study of load transferring and the loading condition encountered in spinal column can be simulated by finite element models. The intervertebral disc is a structure composed of a porous material. Many physical models were developed to simulate this phenomenon. The confounding effects of poroelastic properties and loading conditions on disc mechanical responses are, nevertheless, not cleared yet. The objective of this study was to develop an axisymmetric poroelastic... 

    Dynamic behavior and modal control of beams under moving mass

    , Article Journal of Sound and Vibration ; Volume 306, Issue 3-5 , 2007 , Pages 712-724 ; 0022460X (ISSN) Nikkhoo, A ; Rahimzadeh Rofooei, F ; Shadnam, M. R ; Sharif University of Technology
    Academic Press  2007
    Abstract
    The constitutive equation of an Euler-Bernoulli beam under the excitation of moving mass is considered. The dynamics of the uncontrolled system is governed by a linear, self-adjoint partial differential equation. A Dirac-delta function is used to describe the position of the moving mass along the beam and its inertial effects. An approximate formulation to the problem is obtained by limiting the inertial effect of the moving mass merely to the vertical component of acceleration. Having defined a "critical velocity" in terms of the fundamental period and span of the beam, it is shown that for smaller velocities, the approximate and exact approaches to the problem almost coincide. Since, the... 

    Numerical and analytical simulation of multilayer cellular scaffolds

    , Article Journal of the Brazilian Society of Mechanical Sciences and Engineering ; Volume 42, Issue 5 , 2 May , 2020 Khanaki, H. R ; Rahmati, S ; Nikkhoo, M ; Haghpanahi, M ; Akbari, J ; Sharif University of Technology
    Springer  2020
    Abstract
    Due to the advent and maturity of the additive manufacturing technology, it is possible now to construct complex microstructures with unprecedented accuracy. In addition, to the influence of network unit cell types and porosities in recent years, researchers have studied the number of scaffold layers fabricated by additive manufacturing on mechanical properties. The objective of this paper is to assess the numerical and analytical simulations of the multilayer scaffolds. For this purpose, 54 different regular scaffolds with a unit cell composed of multilayer scaffolds were simulated under compressive loading and compared with the analytical relationships based on the Euler–Bernoulli and... 

    Material property identification of artificial degenerated intervertebral disc models - comparison of inverse poroelastic finite element analysis with biphasic closed form solution

    , Article Journal of Mechanics ; Volume 29, Issue 4 , 2013 , Pages 589-597 ; 17277191 (ISSN) Nikkhoo, M ; Hsu, Y. C ; Haghpanahi, M ; Parnianpour, M ; Wang, J. L ; Sharif University of Technology
    2013
    Abstract
    ABSTRACT Disc rheological parameters regulate the mechanical and biological function of intervertebral disc. The knowledge of effects of degeneration on disc rheology can be beneficial for the design of new disc implants or therapy. We developed two material property identification protocols, i.e., inverse poroelas-tic finite element analysis, and biphasic closed form solution. These protocols were used to find the material properties of intact, moderate and severe degenerated porcine discs. Comparing these two computational protocols for intact and artificial degenerated discs showed they are valid in defining bi-phasic/poroelastic properties. We found that enzymatic agent disrupts the... 

    A meta-model analysis of a finite element simulation for defining poroelastic properties of intervertebral discs

    , Article Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine ; Volume 227, Issue 6 , 2013 , Pages 672-682 ; 09544119 (ISSN) Nikkhoo, M ; Hsu, Y. C ; Haghpanahi, M ; Parnianpour, M ; Wang, J. L ; Sharif University of Technology
    2013
    Abstract
    Finite element analysis is an effective tool to evaluate the material properties of living tissue. For an interactive optimization procedure, the finite element analysis usually needs many simulations to reach a reasonable solution. The metamodel analysis of finite element simulation can be used to reduce the computation of a structure with complex geometry or a material with composite constitutive equations. The intervertebral disc is a complex, heterogeneous, and hydrated porous structure. A poroelastic finite element model can be used to observe the fluid transferring, pressure deviation, and other properties within the disc. Defining reasonable poroelastic material properties of the... 

    Biomechanical response of intact, degenerated and repaired intervertebral discs under impact loading – Ex-vivo and In-Silico investigation

    , Article Journal of Biomechanics ; Volume 70 , March , 2018 , Pages 26-32 ; 00219290 (ISSN) Nikkhoo, M ; Wang, J. L ; Parnianpour, M ; El-Rich, M ; Khalaf, K ; Sharif University of Technology
    Elsevier Ltd  2018
    Abstract
    Understanding the effect of impact loading on the mechanical response of the intervertebral disc (IVD) is valuable for investigating injury mechanisms and devising effective therapeutic modalities. This study used 24 porcine thoracic motion segments to characterize the mechanical response of intact (N = 8), degenerated (Trypsin-denatured, N = 8), and repaired (Genepin-treated, N = 8) IVDs subject to impact loading. A meta-model analysis of poroelastic finite element simulations was used in combination with ex-vivo creep and impact tests to extract the material properties. Forward analyses using updated specimen-specific FE models were performed to evaluate the effect of impact duration. The... 

    Parametric study of the dynamic response of thin rectangular plates traversed by a moving mass

    , Article Acta Mechanica ; Volume 223, Issue 1 , September , 2012 , Pages 15-27 ; 00015970 (ISSN) Nikkhoo, A ; Rofooei, F. R ; Sharif University of Technology
    2012
    Abstract
    The governing differential equation of motion of a thin rectangular plate excited by a moving mass is considered. The moving mass is traversing on the plate's surface at arbitrary trajectories. Eigenfunction expansion method is employed to solve the constitutive equation of motion for various boundary conditions. Approximate and exact expressions of the inertial effects are adopted for the problem formulation. In the approximate formulation, only the vertical acceleration component of the moving mass is considered while in the exact formulation all the convective acceleration components are included in the problem formulation as well. Parametric studies are carried out to investigate the... 

    Using piezoelectric materials to control the dynamic response of a thin rectangular plate under moving mass

    , Article 11th East Asia-Pacific Conference on Structural Engineering and Construction, EASEC-11, Taipei, 19 November 2008 through 21 November 2008 ; January , 2008 Nikkhoo, A ; Rofooei, F. R ; Sharif University of Technology
    2008
    Abstract
    The governing differential equation of motion for an undamped thin rectangular plate with a number of bonded piezoelectric patches on its surface, and arbitrary boundary conditions are derived using Hamilton's principle. A moving mass traveling on an arbitrary trajectory acts as an external excitation for the system. The effect of moving mass inertia is considered using all the out-of-plane translational acceleration components. The method of eigenfunction expansion is used to decouple the equation of motion into a number of coupled ordinary differential equations. A classical closed loop optimal control algorithm is employed to suppress the dynamic response of the system by determining the... 

    A regenerative approach towards recovering the mechanical properties of degenerated intervertebral discs: Genipin and platelet-rich plasma therapies

    , Article Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine ; Volume 231, Issue 2 , 2017 , Pages 127-137 ; 09544119 (ISSN) Nikkhoo, M ; Wang, J. L ; Abdollahi, M ; Hsu, Y. C ; Parnianpour, M ; Khalaf, K ; Sharif University of Technology
    SAGE Publications Ltd  2017
    Abstract
    Degenerative disc disease, associated with discrete structural changes in the peripheral annulus and vertebral endplate, is one of the most common pathological triggers of acute and chronic low back pain, significantly depreciating an individual's quality of life and instigating huge socioeconomic costs. Novel emerging therapeutic techniques are hence of great interest to both research and clinical communities alike. Exogenous crosslinking, such as Genipin, and platelet-rich plasma therapies have been recently demonstrated encouraging results for the repair and regeneration of degenerated discs, but there remains a knowledge gap regarding the quantitative degree of effectiveness and... 

    A Mechanical model for flexible exercise bars to study the influence of the initial position of the bar on lumbar discs and muscles forces

    , Article Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, 25 August 2015 through 29 August 2015 ; Volume 2015-November , 2015 , Pages 3917-3920 ; 1557170X (ISSN) ; 9781424492718 (ISBN) Khalaf, K ; Abdollahi, M ; Nikkhoo, M ; Hoviattalab, M ; Asghari, M ; Ashouri, S ; Nikpour, S ; Kahrizi, S ; Parnianpour, M ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2015
    Abstract
    A single-degree-of-freedom model is considered for flexible exercise bars based on the lumped-element approach. By considering the side segment of a flexible bar as a cantilever beam with an equivalent mass at the free end, its free-vibration response, as well as the forced response under the excitation of the grip, are expressed parametrically. Experiments are performed on a particular flexible bar (FLEXI-BAR) in order to obtain numerical values for quantifying the model's parameters. The model is also computationally simulated to study the response of the flexible bar to various excitations. The results are imported into a multi-segment musculoskeletal software (AnyBody), where the effect... 

    Dynamic response of euler-Bernoulli, Timoshenko and higher-Order beams under a moving mass via RKPM

    , Article 7th European Conference on Structural Dynamics, EURODYN 2008, 7 July 2008 through 9 July 2008 ; 2008 ; 9780854328826 (ISBN) Nikkhoo, A ; Kiani, K ; Mehri, B ; Sharif University of Technology
    University of Southampton, Institute of Sound Vibration and Research  2008
    Abstract
    Discrete motion equations of an Euler-Bernoulli, Timoshenko and higher-order beams under a moving mass are derived for different boundary conditions. To this end, the reproducing kernel particle method (RKPM) has been utilized for spatial discretization, beside the extension of Newmark-β method for time discretization of the beams motion equations. The effects of significant parameters such as the beam's slenderness and velocity of the moving mass on the maximum deflection and bending moment of different beams are studied in some details. The results indicate the existence of a critical beam's slenderness mostly as a function of beam's boundary conditions, in which for slenderness lower than... 

    Investigation of low back pain using system modeling

    , Article Advanced Science Letters ; Volume 19, Issue 5 , 2013 , Pages 1260-1264 ; 19366612 (ISSN) Khan, M. F ; Malik, A. S ; Xia, L ; Wang, J. L ; Nikkhoo, M ; Parnianpour, M ; Khan, M. I ; Sharif University of Technology
    2013
    Abstract
    This paper focuses on characterization of intervertebral disc behavior upon fatigue stress. It consists in in-vitro experiments to measure intervertebral disc deformation with regard to forces applied to produce fatigues test. In this paper, a system modeling based non-invasive method to assess back pain is proposed which may be used for designing of prediction model to predict the failure of intervertebral disc (IVD) experiencing fatigue loading. An artificial compression fracture was simulated in the lower level of vertebra followed by a poly(methyl methacrylate) (PMMA) bone cement injection. Fatigue loading was applied on the specimens and the load was incrementally increased form 650 N... 

    On low back pain: Identification of structural changes in system parameters for fatigue loaded intervertebral disc using PCA

    , Article ICIAS 2012 - 2012 4th International Conference on Intelligent and Advanced Systems: A Conference of World Engineering, Science and Technology Congress (ESTCON) - Conference Proceedings, 12 June 2012 through 14 June 2012 ; Volume 1 , June , 2012 , Pages 378-381 ; 9781457719677 (ISBN) Khan, M. F ; Malik, A. S ; Rozana, F ; Xia, L ; Nikkhoo, M ; Wang, J. L ; Parnianpour, M ; Sharif University of Technology
    2012
    Abstract
    This paper presents the background of low back problem caused by repetitive fatigue loading. We emphasize on mechanism of Intervertebral Disc (IVD) and conditions for which the disc does not recover its original status under repetitive work and cause low back pain. The objective of this study is to identify structural changes in system parameters for fatigue loaded intervertebral disc. Principal component analysis (PCA) is used for studying the behavioral change of spine against cyclic loading as a function of time. Percentage difference and similarity factor was calculated for the analysis. Specimens were applied with impulse testing to measure the stiffness and acceleration after fracture,... 

    Fatigue loaded intervertebral disc analysis for low back pain using nonlinear black-box model

    , Article IFMBE Proceedings ; Volume 39 , 2013 , Pages 513-517 ; 16800737 (ISSN) ; 9783642293047 (ISBN) Khan, M. F ; Malik, A. S ; Xia, L ; Nikkhoo, M ; Wang, J. L ; Parnianpour, M ; Humayun, J ; Sharif University of Technology
    2013
    Abstract
    This paper presents recent developments on effects of rest and fatigue loading on properties of healthy vertebra discs. A comparison of different approaches used in literature to study the properties of intervertebral disc is presented. The major achievements in this area so far are discussed in the context of their advantages and disadvantages. The past approaches are based on bio-mechanical models which mostly used statistical techniques for the analysis and estimation of fatigue loaded Intervertebral Disc (IVD). However, those modeling techniques were not flexible enough for analysis of customized tests. In this paper, we applied System Identification (SI) based NLARX modeling technique... 

    On the response spectrum of Euler-Bernoulli beams with a moving mass and horizontal support excitation

    , Article Mechanics Research Communications ; Volume 47 , January , 2013 , Pages 77-83 ; 00936413 (ISSN) Zarfam, R ; Khaloo, A. R ; Nikkhoo, A ; Sharif University of Technology
    Elsevier Ltd  2013
    Abstract
    Abstract In this study, the response spectrum of a time-varying system such as a beam subjected to moving masses under a harmonic and earthquake support excitations is explored. The excitations are supposed to act on the horizontal directions of the beam axis. The inertial effect of the moving masses on the natural frequencies of the beam for different cases of loading is investigated and a critical value of a so called parameter "mass staying time" is presented to avoid dynamic instability of the system. Finally, some 3D response spectra for different supports excitations as well as the beam natural frequencies are depicted  

    Dynamic response of geometrically nonlinear, elastic rectangular plates under a moving mass loading by inclusion of all inertial components

    , Article Journal of Sound and Vibration ; Volume 394 , 2017 , Pages 497-514 ; 0022460X (ISSN) Rahimzadeh Rofooei, F ; Enshaeian, A ; Nikkhoo, A ; Sharif University of Technology
    Academic Press  2017
    Abstract
    Dynamic deformations of beams and plates under moving objects have extensively been studied in the past. In this work, the dynamic response of geometrically nonlinear rectangular elastic plates subjected to moving mass loading is numerically investigated. A rectangular von Karman plate with various boundary conditions is modeled using specifically developed geometrically nonlinear plate elements. In the available finite element (FE) codes the only way to distinguish between moving masses from moving loads is to model the moving mass as a separate entity. However, these procedures still do not guarantee the inclusion of all inertial effects associated with the moving mass. In a prepared... 

    Oxido-peroxido W(VI)-histidine–MgAl-layered double hydroxide composite as an efficient catalyst in sulfide oxidation

    , Article Applied Organometallic Chemistry ; Volume 32, Issue 6 , 2018 ; 02682605 (ISSN) Nikkhoo, M ; Amini, M ; Morteza, S ; Farnia, F ; Bayrami, A ; Bagherzadeh, M ; Gautam, S ; Chae, K. H ; Sharif University of Technology
    John Wiley and Sons Ltd  2018
    Abstract
    Oxido-peroxido W(VI)-histidine–MgAl-layered double hydroxide composite was prepared by using MgAl-layered double hydroxide as a host and oxido-peroxido W(VI)-histidine complex as a guest. The composite was characterized by XRD, IR, EDX,SEM and TEM techniques. This composite is tested for catalytic selective sulfoxidation reactions using hydrogen peroxide as oxidant showing good to moderate conversion along with high selectivity. Copyright © 2018 John Wiley & Sons, Ltd