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The development of a dental light curable PRFe-loaded hydrogel as a potential scaffold for pulp-dentine complex regeneration: An in vitro study
, Article International Endodontic Journal ; Volume 56, Issue 4 , 2023 , Pages 447-464 ; 01432885 (ISSN) ; Abdekhodaie, M. J ; Saadatmand, M ; Nekoofar, M. H ; Dummer, P. M. H ; Sharif University of Technology
John Wiley and Sons Inc
2023
Abstract
Aim: The study aimed to develop a bicomponent bioactive hydrogel formed in situ and enriched with an extract of platelet-rich fibrin (PRFe) and to assess its potential for use in pulp-dentine complex tissue engineering via cell homing. Methodology: A bicomponent hydrogel based on photo-activated naturally derived polymers, methacrylated chitosan (ChitMA) and methacrylated collagen (ColMA), plus PRFe was fabricated. The optimized formulation of PRFe-loaded bicomponent hydrogel was determined by analysing the mechanical strength, swelling ratio and cell viability simultaneously. The physical, mechanical, rheological and morphological properties of the optimal hydrogel with and without PRFe...
Computational modeling of intraocular gas dynamics
, Article Physical Biology ; Volume 12, Issue 6 , 2015 ; 14783967 (ISSN) ; Abdekhodaie, M. J ; Cheng, Y. L ; Sharif University of Technology
Institute of Physics Publishing
2015
Abstract
The purpose of this study was to develop a computational model to simulate the dynamics of intraocular gas behavior in pneumatic retinopexy (PR) procedure. The presented model predicted intraocular gas volume at any time and determined the tolerance angle within which a patient can maneuver and still gas completely covers the tear(s). Computational fluid dynamics calculations were conducted to describe PR procedure. The geometrical model was constructed based on the rabbit and human eye dimensions. SF6 in the form of pure and diluted with air was considered as the injected gas. The presented results indicated that the composition of the injected gas affected the gas absorption rate and gas...
Simulation of Transport Phenomena in Gas Injection in the Eye
, M.Sc. Thesis Sharif University of Technology ; Abdekhodaie, Mohammad Jafar (Supervisor) ; Goodarznia, Iraj (Supervisor)
Abstract
Retinal detachment is a disorder of the eye in which a part or entire retina detaches from underlying layers. It is a medical emergency and if it is not treated, all vision may be lost. Surgery is the only way to treat retinal detachment. Pneumatic retinopexy (PR) is an office-based procedure for repairing some retinal detachment. PR has three cardinal steps: applying laser or cryopexy around all breaks to seal them, injection of gas into the vitreous cavity and appropriate head position so that the bubble closes the retinal breaks.
In this thesis, we are trying to model PR procedure and predict the behavior of intraocular gas. In general, once the gas is injected into the eye, because...
In this thesis, we are trying to model PR procedure and predict the behavior of intraocular gas. In general, once the gas is injected into the eye, because...
Simulating a Micro-Swimmer with Star Model at Low Reynolds Number
, M.Sc. Thesis Sharif University of Technology ; Ejtehadi, Mohammad Reza (Supervisor)
Abstract
To generalize the Najafi_Golestanian swimmer model from one dimension to two dimensions and to demonstrate its chemotaxis ability, here we introduce a model that consists of four spheres with same radius connected by three arms and we call it a star swimmer. Each arm can be in two states, contracted and expanded (initial length). So that at the head of each arm there are molecular motors that can act as enzymes and as a result of chemical interaction with specific activating substances in their environment, cause the entire body of the tiny swimmer to move and rotate. The change in the concentration of the activating substance in the environment breaks the symmetry of the preferred state of...
Photoreactive hydrogels based on type I collagen extracted from different sources as scaffolds for tissue engineering applications: a comparative study
, Article Materialia ; Volume 27 , 2023 ; 25891529 (ISSN) ; Mahdavi, S. S ; Abdekhodaie, M. J ; Nekoofar, M. H ; Baradaran Rafii, A ; Sharif University of Technology
Elsevier B.V
2023
Abstract
Collagen-based hydrogels are promising constructs used frequently as scaffolds in various tissue engineering applications. The source of collagen extraction can influence the physiochemical properties, mechanical strength, as well as cellular behaviour of the tissue-engineered hydrogels. In the present study, type I collagen was isolated from three different animal sources, namely bovine Achilles tendon, bighead carp fish skin, and rat tail tendons. After characterizing the extracted collagens, their structures were modified via covalent functionalization of the free amines with methacrylate groups. Methacrylated collagens were combined with PEG-diacrylate to act as three-dimensional...
Construction of A Polymeric Scaffold for Dental Pulp Regeneration
, Ph.D. Dissertation Sharif University of Technology ; Abdekhodaie, Mohammad Jafar (Supervisor) ; Saadatmand, Maryam (Supervisor) ; Nekoofar, Mohammad Hossein (Supervisor)
Abstract
Pulp necrosis in immature teeth disrupts root development and predisposes roots to fracture as a consequence of their thin walls and open apices. Regenerative endodontics is a developing treatment modality whereby necrotic pulps are replaced with newly formed healthy pulp-like tissue. Many clinical studies have demonstrated the potential of this strategy to stimulate root maturation and apical root-end closure. However, clinical outcomes are patient-dependent and unpredictable. The development of predictable clinical protocols is achieved through the interplay of the three classical elements of tissue engineering, namely, stem cells, signaling molecules, and scaffolds. Scaffolds provide...
Secrecy capacity scaling in large cooperative wireless networks
, Article IEEE Transactions on Information Theory ; Volume 63, Issue 3 , 2017 , Pages 1923-1939 ; 00189448 (ISSN) ; Papadimitratos, P. P ; Sharif University of Technology
Institute of Electrical and Electronics Engineers Inc
2017
Abstract
We investigate large wireless networks subject to security constraints. In contrast to point-to-point, interferencelimited communications considered in prior works, we propose active cooperative relaying-based schemes. We consider a network with nl legitimate nodes, ne eavesdroppers, and path loss exponent α ≥ 2. As long as n2e (log(ne))γ = o(nl ), for some positive γ , we show that one can obtain unbounded secure aggregate rate. This means zero-cost secure communication, given fixed total power constraint for the entire network. We achieve this result through: 1) the source using Wyner randomized encoder and a serial (multi-stage) block Markov scheme, to cooperate with the relays and 2) the...
Fast estimation of connectivity in fractured reservoirs using percolation theory
, Article SPE Journal ; Volume 12, Issue 2 , 2007 , Pages 167-178 ; 1086055X (ISSN) ; King, P. R ; Nuratza, P ; Sharif University of Technology
Society of Petroleum Engineers (SPE)
2007
Abstract
Investigating the impact of geological uncertainty (i.e., spatial distribution of fractures) on reservoir performance may aid management decisions. The conventional approach to address this is to build a number of possible reservoir models, upscale them, and then run flow simulations. The problem with this approach is that it is computationally very expensive. In this study, we use another approach based on the permeability contrasts that control the flow, called percolation approach. This assumes that the permeability disorder of a rock can be simplified to either permeable or impermeable. The advantage is that by using some universal laws from percolation theory, the effect of the complex...
A new decoding scheme for errorless codes for overloaded CDMA with active user detection
, Article 2011 18th International Conference on Telecommunications, ICT 2011, Ayia Napa, 8 May 2011 through 11 May 2011 ; 2011 , Pages 201-205 ; 9781457700248 (ISBN) ; Pad, P ; Delgosha, P ; Marvasti, F ; Sharif University of Technology
2011
Abstract
Recently, a new class of binary codes for overloaded CDMA systems are proposed that not only has the ability of errorless communication but also suitable for detecting active users. These codes are called COWDA. In [1], a Maximum Likelihood (ML) decoder is proposed for this class of codes. Although the proposed scheme for coding/decoding shows impressive performance, the decoder can be significantly improved. In this paper, by assuming practical conditions for the traffic in the system, we suggest and prove an algorithm that increases the performance of the decoder several orders of magnitude (the Bit-Error-Rate (BER) is divided by a factor of about 400 in some E b/N0's). The algorithm...
Estimation of the Effective Permeability of Heterogeneous Porous Media by Using Percolation Concepts
, Article Transport in Porous Media ; Volume 114, Issue 1 , 2016 , Pages 169-199 ; 01693913 (ISSN) ; Gago, P. A ; King, P. R ; Sharif University of Technology
Springer Netherlands
2016
Abstract
In this paper we present new methods to estimate the effective permeability (keff) of heterogeneous porous media with a wide distribution of permeabilities and various underlying structures, using percolation concepts. We first set a threshold permeability (kth) on the permeability density function and use standard algorithms from percolation theory to check whether the high permeable grid blocks (i.e., those with permeability higher than kth) with occupied fraction of “p” first forms a cluster connecting two opposite sides of the system in the direction of the flow (high permeability flow pathway). Then we estimate the effective permeability of the heterogeneous porous media in different...
Percolation-based effective permeability estimation in real heterogeneous porous media
, Article 15th European Conference on the Mathematics of Oil Recovery, 29 August 2016 through 1 September 2016 ; 2016 ; 9462821933 (ISBN); 9789462821934 (ISBN) ; Gago, P ; King, P ; DCSE; Schlumberger; Shell ; Sharif University of Technology
European Association of Geoscientists and Engineers
2016
Abstract
It has long been understood that flow behavior in heterogeneous porous media is largely controlled by the continuity of permeability contrasts. With this in mind, we are looking in new methods for a fast estimation of the effective permeability which concentrates on the properties of the percolating cluster. From percolation concepts we use a threshold permeability value (Kth) by which the gridblocks with the highest permeability values connect two opposite side of the system in the direction of the flow. Those methods can be applied to heterogeneous media of a range of permeabilities distribution and various underlying structures. We use power law relations and weighted power averages that...
Optimization of sputtering parameters for the deposition of low resistivity indium tin oxide thin films
, Article Acta Metallurgica Sinica (English Letters) ; Vol. 27, issue. 2 , Apr , 2014 , p. 324-330 ; Bagheri, B ; Yazdanfar, P ; Rashidian, B ; Sasanpour, P ; Sharif University of Technology
2014
Abstract
Indium tin oxide (ITO) thin films have been deposited using RF sputtering technique at different pressures, RF powers, and substrate temperatures. Variations in surface morphology, optical properties, and film resistances were measured and analyzed. It is shown that a very low value of sheet resistance (1.96 ω/sq.) can be achieved with suitable arrangement of the deposition experiments. First, at constant RF power, deposition at different pressure values is done, and the condition for achieving minimum sheet resistance (26.43 ω/sq.) is found. In the next step, different values of RF powers are tried, while keeping the pressure fixed on the previously found minimum point (1-2 Pa). Finally,...
Comparative assessment of gasification based coal power plants with various CO2 capture technologies producing electricity and hydrogen
, Article Energy and Fuels ; Volume 28, Issue 2 , 20 February , 2014 , Pages 1028-1040 ; ISSN: 08870624 ; Kumar, P ; Hosseini, A ; Yang, A ; Fennell, P ; Sharif University of Technology
2014
Abstract
Seven different types of gasification-based coal conversion processes for producing mainly electricity and in some cases hydrogen (H2), with and without carbon dioxide (CO2) capture, were compared on a consistent basis through simulation studies. The flowsheet for each process was developed in a chemical process simulation tool "Aspen Plus". The pressure swing adsorption (PSA), physical absorption (Selexol), and chemical looping combustion (CLC) technologies were separately analyzed for processes with CO2 capture. The performances of the above three capture technologies were compared with respect to energetic and exergetic efficiencies, and the level of CO2 emission. The effect of air...
Synthesis of nanosize single-crystal hydroxyapatite via mechanochemical method
, Article Materials Letters ; Volume 63, Issue 5 , 2009 , Pages 543-546 ; 0167577X (ISSN) ; Honarmandi, P ; Ebrahimi Kahrizsangi, R ; Honarmandi, P ; Sharif University of Technology
2009
Abstract
Single-crystal hydroxyapatite (HAp) nanorods and nanogranules have been synthesized successfully by a mechanochemical process using two distinct experimental procedures. The experimental outcomes are characterized by transmission electron microscopy (TEM), and powder X-ray diffraction (XRD) techniques. In this work, the feasibility of using polymeric milling media to prepare hydroxyapatite nanoparticles is described. The resulting hydroxyapatite powder exhibits an average size of about 20 to 23 nm. Final results indicate that the proposed synthesis strategy provides a facile pathway to obtain single-crystal HAp with high quality and suitable morphology. © 2008 Elsevier B.V. All rights...
Migrating to Cloud-Native architectures using microservices: An experience report
, Article Workshops on CLIoT, WAS4FI, SeaClouds, CloudWay, IDEA, FedCloudNet 2015 held in conjunction with European Conference on Service-Oriented and Cloud Computing, ESOCC 2015, 15 September 2015 through 17 September 2015 ; Volume 567 , 2016 , Pages 201-215 ; 18650929 (ISSN); 9783319333120 (ISBN) ; Heydarnoori, A ; Jamshidi, P ; Celesti A ; Leitner P ; Sharif University of Technology
Springer Verlag
2016
Abstract
Migration to the cloud has been a popular topic in industry and academia in recent years. Despite many benefits that the cloud presents, such as high availability and scalability, most of the on-premise application architectures are not ready to fully exploit the benefits of this environment, and adapting them to this environment is a non-trivial task. Microservices have appeared recently as novel architectural styles that are native to the cloud. These cloud-native architectures can facilitate migrating on-premise architectures to fully benefit from the cloud environments because non-functional attributes, like scalability, are inherent in this style. The existing approaches on cloud...
Study the effect of connectivity between two wells on secondary recovery efficiency using percolation approach
, Article 15th European Conference on the Mathematics of Oil Recovery, ECMOR 2016, 29 August 2016 through 1 September 2016 ; 2016 ; 9462821933 (ISBN); 9789462821934 (ISBN) ; Masihi, M ; King, P. R ; Gago, P. A ; Sharif University of Technology
European Association of Geoscientists and Engineers, EAGE
2016
Abstract
Estimating available hydrocarbon to be produced during secondary oil recovery is an ongoing activity in field development. The primary plan is normally scheduled during early stage of field's life through master development plan studies. During this period, due to the lake of certain data, estimation of the field efficiency is usually based on rules of thumb and not detailed field characterization. Hence, there is a great motivation to produce simpler physically-based methodologies. The minimum necessity inputs of percolation approach make it a useful tool for foration performance prediction. This approach enables us to attain a better assessment of the efficiency of secondary recovery...
Modeling of CO2-brine interfacial tension: Application to enhanced oil recovery
, Article Petroleum Science and Technology ; Volume 35, Issue 23 , 2017 , Pages 2179-2186 ; 10916466 (ISSN) ; Abbasi, P ; Baghban, A ; Zargar, G ; Abbasi, P ; Sharif University of Technology
2017
Abstract
Development of reliable and accurate models to estimate carbon dioxide–brine interfacial tension (IFT) is necessary, since its experimental measurement is time-consuming and requires expensive experimental apparatus as well as complicated interpretation procedure. In the current study, feed forward artificial neural network is used for estimation of CO2–brine IFT based on data from published literature which consists of a number of carbon dioxide–brine interfacial tension data covering broad ranges of temperature, total salinity, mole fractions of impure components and pressure. Trial-and-error method is utilized to optimize the artificial neural network topology in order to enhance its...
Improved advection algorithm of computational modeling of free surface flow using structured grids
, Article Computer Methods in Applied Mechanics and Engineering ; Volume 195, Issue 7-8 , 2006 , Pages 775-795 ; 00457825 (ISSN) ; Abdollahi, J ; Homayonifar, P ; Varahram, N ; Davami, P ; Sharif University of Technology
2006
Abstract
In the present study a finite difference method has been developed to model the transient fluid flow and heat transfer. A single fluid has been selected for modeling of mold filling and The SOLA-VOF 3D technique was modified to increase the accuracy of simulation of filling phenomena for shape castings. The model was then evaluated with the experimental methods. Refereeing to the experimental and simulation results a good consistency and the accuracy of the suggested model are confirmed. © 2005 Published by Elsevier B.V
Modelling of air pressure effects in casting moulds
, Article Modelling and Simulation in Materials Science and Engineering ; Volume 13, Issue 6 , 2005 , Pages 903-917 ; 09650393 (ISSN) ; Homayonifar, P ; Babaei, R ; Asgari, K ; Davami, P ; Sharif University of Technology
2005
Abstract
In the casting process, as a mould is filled with molten metal, air escapes through the vents. Air pressure in the mould cavity has serious effects upon the filling behaviour such as surface profile of the molten metal and filling time. In this project a computational model was developed for calculation of air pressure during the mould filling. A 3D single phase code based on the SOLA-VOF algorithm was used for the prediction of the fluid flow. The ideal gas assumption, conservation of mass equation and Bernoulli law were used for the calculation of air pressure. A new algorithm was developed to interpolate air pressure on the surface cells. The creation of air pressure was correlated with...
Random data and key generation evaluation of some commercial tokens and smart cards
, Article 2014 11th International ISC Conference on Information Security and Cryptology, ISCISC 2014 ; 2014 , p. 49-54 ; Sarmadi, S. B ; Yousefi, P ; Gorji, P ; Jalili, R ; Sharif University of Technology
2014
Abstract
In this paper, we report our evaluation of the strength of random number generator and RSA key-pair generator of some commercially available constrained hardware modules, i.e., tokens and smart cards. That was motivated after recent related attacks to RSA public keys, which are generated by constrained network devices and smart cards, and turned out to be insecure due to low-quality randomness. Those attacks are mostly computing pair-wise GCD between the moduli in public keys, and resulted in breaking several thousands of these keys. Our results show that most of the tested hardware modules behave well. However, some have abnormal or weak random generators which seem to be unsuitable for...