Sharif Digital Repository

In this study, a nonlinear poroelastic model of intervertebral disc as an infrastructure was developed. Moreover, a new element was defined consisting a disc (Viscoelastic Euler Beam Element) and a vertebra (Rigid Link) as a unit element. Using the new element, three different viscoelastic finite element models were prepared for lumbar motion segment (L4/L5). Prolonged loading (short-term and long-term creep) and cyclic loading were applied to the models and the results were compared with results of in vivo tests. Simplification of the models by using the new element leads to reduction of the runtime of the models in dynamic analyses to few minutes without losing the accuracy in the results  

Aim. The compressive loads on the tibiofemoral joint are normally assumed to be borne solely via contact and pressing of the cartilage surfaces of tibia and femur. However, recent findings suggest that non-contact load-bearing mechanisms are active in the joint as well. In this context, a non-contact load-bearing mechanism involving soft tissue connections outside the tibiofemoral joint has been hypothesized as well. This paper addresses the validity of this hypothesis and the possible involvement of several soft tissue connections outside the joint. Methods. Sheep stifle (knee) joints were studied in vitro. The specimens were loaded in fixed displacement. Various soft tissues outside the... 

Every year many people suffer from knee injuries. Previous studies on patients with knee injuries has shown that about 40% percent of knee injuries are ligament injuries, and about 50% of the ligament injuries are the Anterior Cruciate Ligament (ACL) injuries [1–2]. Knee arthrometers are widely used to diagnose ACL injuries, along with other methods [3–4]. In the current research, a knee arthrometer which was developed to provide an accurate measurement of AP displacement of the knee [5] was used to measure anterior laxity of the knees of 20 subjects, and the results were analyzed to find better criteria to diagnose ACL rupture using knee arthrometers  

The way central nervous system manages the excess degrees of freedom to solve kinetic redundancy of musculoskeletal system remains an open question. In this study, we utilise the concept of synergy formation as a simplifying control strategy to find the muscle recruitment based on summation of identified muscle synergies to balance the biomechanical demands (biaxial external torque) during an isometric shoulder task. A numerical optimisation-based shoulder model was used to obtain muscle activation levels when a biaxial external isometric torque is imposed at the shoulder glenohumeral joint. In the numerical simulations, 12 different shoulder torque vectors in the transverse plane are... 

Despite development of accurate musculoskeletal models for human lumbar spine, the methods for prediction of muscle activity patterns in movements lack proper association with corresponding sensorimotor integrations. This paper uses the directional information of the Jacobian of the musculoskeletal system to orchestrate adaptive critic-based fuzzy neural controller modules for controlling a complex nonlinear redundant musculoskeletal system. The proposed controller is used to control a 3D 3-degree of freedom (DOF) musculoskeletal model of trunk, actuated by 18 muscles. The controller is capable of learning to control from sensory information, without relying on pre-assumed model parameters.... 

As balance is the foundation for all voluntary motor skills, considerable research has been conducted to evaluate postural control in patients with low back pain (LBP). Although reliability is a population-specific property, to the authors' knowledge, there has been no study to determine the test-retest reliability of the center of pressure (COP) measures in the general population of LBP patients. As many as 11 patients with a history of nonspecific LBP randomly completed postural measurements with three levels of difficulty (rigid surface-eyes open, rigid surface-eyes closed, and foam surface-eyes closed) in two sessions. The COP data were used to calculate standard deviation of amplitude,... 

Trunk muscle forces and internal loads are computed under simulated standing postures while carrying a load using a nonlinear finite element model of the T1-S1 spine with realistic nonlinear load-displacement properties. A novel kinematics-based algorithm is applied that exploits a set of a priori known spinal sagittal rotations to solve the redundant active-passive system. The loads consist of upper body gravity distributed along the spine plus 200 N held in hands either in front or on sides. Predictions are in good agreement with reported measurements of posture, muscle EMG and intradiscal pressure. Minimal changes in posture (posterior pelvic tilt and lumbar flattening) substantially... 

Frontal vehicle crashes have been a leading cause of spinal injuries in recent years. Reconstruction of frontal crashes using computational models and spinal load analysis helps us understand the patterns of injury and load propagation during frontal crashes. By reconstructing a real crash test and using a viscoelastic crash dummy model, spinal injury patterns were analyzed. The results indicated that a moderate crash with an impact speed of 56 km/h leads to injuries in L1-L2 and L5-S1 levels (L for lumbar and S for sacral vertebrae). The largest spinal loads and injuries were mainly observed immediately after the airbag deployment when the peak of the crash acceleration transpires. Also,... 

The dummies currently used for predicting vehicle occupant response during frontal crashes or whole-body vibration provide insufficient information about spinal loads. Although they aptly approximate upper-body rotations in different loading scenarios, they overlook spinal loads, which are crucial to injury assessment. This paper aims to develop a modified dummy finite element (FE) model with a detailed viscoelastic lumbar spine. This model has been developed and validated against in-vitro and in-silico data under different loading conditions, and its predicted ranges of motion (RoM) and intradiscal pressure (IDP) maintain close correspondence with the in-vitro data. The dominant frequency... 

Whole-body vibration (WBV) has been identified as one of the serious risk factors leading to spinal disorders, particularly in professional drivers. Although the influential factors in this area have been investigated epidemiologically, finite element (FE) modeling can efficiently help us better understand the problem. In this study, a modified HYBRID III dummy FE model which was enhanced by detailed viscoelastic discs in the lumbar region was utilized to simulate the effect of WBV on lumbar spine loads. Spinal responses to the vertical sinusoidal vibrations of a generic seat were obtained and spinal injury risk factors were calculated. Effects of variation of excitation frequencies, three... 

A dynamic model of an above-knee prosthesis during the complete gait cycle was developed. The model was based on a two-dimensional multi-body mechanical system and included a hydraulic and an elastic controller for the knee and a kinematical driver controller for the prosthetic ankle. The equations of motion were driven using Lagrange method. Simulation of the foot contact was conducted using a two-point penetration contact model. The knee elastic and hydraulic controller units, the knee extension stop, and the kinematical driver controller of the ankle were represented by a spring and a dashpot, a nonlinear spring, and a torsional spring-damper within a standard prosthetic configuration.... 

Numerous disciplines are engaged in studies involving motor control. In this study, we have used a single link system with a pair of muscles that are excited with alpha and gamma signals to achieve an oscillatory movement with variable amplitude and frequency. The system is highly nonlinear in all its physical and physiological attributes. The major physiological characteristics of this system are simultaneous activation of a pair of nonlinear muscle-like-actuators for control purposes, existence of nonlinear spindle-like sensors and Golgi tendon organ-like sensor, actions of gravity and external loading. Transmission delays are included in the afferent and efferent neural paths to account... 

In this study, we have used a single link system with a pair of muscles that are excited with alpha and gamma signals to achieve an oscillatory movement with variable amplitude and frequency. This paper proposes a reinforcement learning method with an Actor-Critic architecture instead of middle and low level of central nervous system (CNS). The Actor in this structure is a two layer feedforward neural network and the Critic is a model of the cerebellum. The Critic is trained by State-Action-Reward-State-Action (SARSA) method. The system showed excellent tracking capability and after 280 epochs the RMS error for position and velocity profiles were 0.02, 0.04 radian and radian/sec,... 

It has been hypothesized that the muscular efforts exerted during standing may be altered by changes in personal factors, such as the body stature and muscular strength. The goal of this work was to assess the contribution of leg muscles using a biomechanical model in different physical conditions and various initial postures. An optimized inverse dynamics model was employed to find the maximum muscular effort in 23,040 postures. The simulation results showed that mid-range knee flexion could help the healthy and strong individuals maintain balance, but those with weaker muscle strength required more knee flexion. Individuals of weak muscular constitution as well as those with tall stature... 

In the adolescent idiopathic scoliosis (AIS) treatment, a brace is prescribed to the patients who have 20 to 45° curves on their spines to prevent the disorder's advancement. For the analysis of Milwaukee brace effects during time, finite element models (FEMs) of the spine (the thoracolumbar region) and the ribcage (contained 10 pairs of the ribs and the sternum) were prepared for two patients. For modeling the spine part, a new element was used in which a disc (as viscoelastic 3D beam) and a vertebra (as rigid link) were modeled as an element and the ribs and the sternum modeled by 3D elastic beams. The gravity, Milwaukee brace constraints and the forces of the brace's different regions... 

A new wearable assistive device (WAD) was developed to decrease required force on the lumbar spine in static holding tasks. In order to obtain moments on lumbar spine in two conditions, with and without WAD, a biomechanical static model was used for estimation of external moments on lumbar spine. The results of biomechanical models indicated that there was a reduction in the lumbar moment ranging from 20% to 43% using WAD depending on the load and flexion angle. A total of 15 male healthy subjects were tested to experimentally verify the predicted reduction of external moments on the spine by wearing WAD. Normalized electromyography (EMG) of the right and left lumbar and thoracic erector... 

Human motion planning studies are of considerable importance in producing human-like trajectories for various industrial or clinical applications (e.g. assistive robots). In this case, the capability of Central Nervous System (CNS) in generating a large repertoire of actions can be inspirational to develop more efficient motion planning approaches. Here, inspired by structural and functional modularity in the CNS, a novel modular and hierarchical model is developed to plan the sit-to-stand (STS) transfer under varying environmental conditions. In this model, the planning process is distributed among several functionally simple modules. The cooperation of modules enables the model to plan the... 

Although several studies have applied traditional linear measures to evaluate postural control of patients with multiple sclerosis (MS), little is known about the nonlinear dynamics of this patient group. In this study, recurrence quantification analysis (RQA), a well documented nonlinear method, was used to compare the nonlinear dynamical structure of postural sway in two groups consisting of MS patients (. n=. 23) and healthy matched controls (. n=. 23). The study focuses on three levels of postural difficulty consisting of (1) standing on a rigid surface (force platform) with eyes open, (2) standing on a rigid surface with eyes closed, and (3) standing on a foam surface with eyes closed.... 

Investigation of the relationship between different types of mechanical loading and the failure of the intervertebral disc requires a well-defined finite element model. The objective of this paper was to develop and validate a nonlinear axisymmetric poroelastic finite element model of intervertebral disc and show its capability for studying the time-dependent response. After presenting the poroelastic model of intervertebral disc, the results of prolonged (short-term and long-term creep tests) and cyclic loading were compared with in vivo and in vitro experimental data. The trends predicted by FE model agreed well with measured experimental data and showed its validity for dynamic analysis.... 

Understanding the relationship between different kinds of mechanical loading and the failure of the intervertebral disc is difficult to study in vivo and in vitro. Through finite element studies some of these issues may be overcome enabling more detailed assessment of the biomechanical behavior of the intervertebral disc. The objective of this paper is to develop a nonlinear axisymmetric poroelastic finite element model of intervertebral disc and show its capability for studying the time-dependent response of disc. After comparison of the response of different models in quasi-static analysis, the poroelastic model of intervertebral disc is presented and the results of a short-term and...