Sharif Digital Repository

Reliance of drug production to batch processes makes the drug supply chain extremely long and the quality control process difficult. Carnitine (vitamin Bt; 3-hydroxy-4-trimethylammonio-butanoate) is a quaternary ammonium compound biosynthesized from the amino acids lysine and methionine. In living cells, Carnitine is required for the transport of fatty acids from the cytosol into the mitochondria during the breakdown of lipids for the generation of metabolic energy. Moreover, it is used as a nutritional supplement. As a drug, L-carnitine is utilized to increase cardiac output, to improve myocardial function, and to treat carnitine deficiency, especially after hemodialysis. In this study, the... 

Today, with the development of technology, cyberattacks are on the rise. Personal and corporate computer systems can be exposed to various threats and dangers of hackers and malware, including information theft, forgery, and denial of service, which can cause great material and moral damage to individuals and organizations. So, it is necessary to take security measures in this regard. Many security mechanisms are available to prevent security vulnerabilities against various threats. In this study, first, after carefully studying network attacks, we identify the criteria for identifying attacks that can be executed in network traffic and explain how to calculate them. The current research... 

Coming to the generation of technology, where everything is possible through the Internet contributes a significant proportion to privacy protection. Several Privacy protection technologies have been launched to maintain the confidentiality of user information. Tor, also known as an Onion Router, is indeed the largest global anonymized network technology, including over 7000 distinct domain controller endpoints located all over the globe. Various kinds of wrongdoings are increasing day by day such as terrorism, abuse of the child is increasing using the network. To stop this monitoring plan is needed to develop. To enable this all the hacking mechanisms along with the architecture were... 

Iris segmentation is an essential step in a medical imaging-based automated diagnosis system. The operation of dividing a digital image into areas with different characteristics and setting objectives is known as image segmentation. The extraction of the iris from unnecessary sections of the image is very important for any biometric device. Eyelid / eyelash obstruction, special reflections, intensity heterogeneity, and an irregular iris border, are considered as noise which affect the iris segmentation process. Focusing on Fuzzy C-Means (FCM) clustering and Grasshopper Optimization Algorithm (GOA), we present a new and efficient method for dividing iris-filled, annoying, and iris limits that... 

Classification of Traffic Internet obtained early interest in the computer science community. Various methods have been presented for classifying the traffic of Internet to manage both security and Quality of Service (QoS). Nonetheless, traditional methods of classification including scheme of Transmission Control Protocol/Internet Protocol (TCP/IP) have not been accepted because of their complicated management. Classification method of network through learning algorithms of machine is the most popular classification method of traffic at this time. ELM was proposed as a modern algorithm of learning for the Single-hidden Layer Feed Forward Neural Networks (SLFNs). Meanwhile, learning process... 

Simulation of biophysical neural networks enables the interpretation and integration of fast-growing and different experimental datasets. The widely used NEURON simulator allows molecular-to-network simulation. However, it is still a very hard challenge to create large-scale models and operate parallel simulations applying NEURON. SUNY Downstate developed the NetPyNE means networks using Python and NEURON, which was funded by the New York State Department of Health and some other institutions. NetPyNE is a Python-based tool that enables the development of data-driven multi-scale network models in NEURON through both programmatic and graphical interfaces. It is a powerful tool for parallel... 

Frequently using Personal Identification Information has escalated the security concerns of bank accounts, emails, daily transactions, and other activities. Therefore, user access to such apps must be controlled. Traditional personal verification methods offer limited security because they might need to be remembered or stolen. Therefore, Biometric authentication, which identifies persons by their unique biological information, is gaining popularity. However, palm vein identification is highly secure because the vein patterns are not duplicated in other people, even in monozygotic twins. Moreover, it has a liveness detection and is convenient since the vein pattern cannot be faked,... 

The main goal of this thesis is the design and development of a rehabilitation device for helping patients “to improve blood circulation” & retain and recover their abilities if possible that were lost during the stroke or a accident like that (my research in karaj/iran shows that it is possible by just movement of the specific body part). The focus is on hand in this thesis because Injuries to the hand are common and can be very debilitating since our hands are our primary means for interacting with our world. For rehabilitation in case of human hand there are several practices that should be done for patients either in home or in a rehabilitation center, time and money that is supposed to... 

In the past few decades, shaking tables are widely used to evaluate system response of structures under seismic excitations. These devices are used without any fundamental research performed on a shaking table system as an entity model. In most of these studies for simplicity, it is assumed that there exist no considerable vibration and displacement around the shaking tables, and no attention is paid to the peripheral substances such as soil settled under the foundation.
In this thesis, result of ambient vibration test on shaking table system (solid deck, concrete foundation and soil layer) has been presented. Precise sensors known as low frequency and high accuracy accelerometers have... 

Out of several ground improvement techniques available, stone columns have been widely used. This technique has been successfully applied to increase the bearing capacity and to reduce the settlement for foundation of structures like liquid storage tanks, earthen embankments, raft foundations, etc., where a relatively large settlement is permissible. This technique has, generally, been proven successful in increasing the stiffness of weak soils, upgrading their safe bearing capacity, and reducing their total and differential settlements, as well as speeding up their consolidation process. The beneficial effects of stone column installation in weak deposits is manifested in the form of... 

Laminar forced convection flow through a channel partially filled with a porous material was numerically studied in this thesis. The Navier-Stokes and Brinkman-Forchheimer equations were used to model the fluid flow in the free and porous regions, respectively. Coupling of the pressure and velocity fields was resolved using the SIMPLEC algorithm. The local thermal equilibrium was adopted in the energy equation. The effects of the thermal conductivity ratio, Darcy number, porosity, Reynolds number and height of the porous insert on velocity and temperature field were investigated. The results show that the flow behavior and its associated heat transfer are susceptible to the variation of the... 

In the present study, a new version of haptic devices is presented in which user’s hand is in contact with the device just while collision with virtual surface. In this system, the position of user’s finger can be traced by using a camera and the haptic device follows user’s finger at the distance of about two centimeters. While the haptic device approaches to the virtual surface, gradually reduces its speed and stops about two centimeters distant of virtual plane. Then user’s hand collides with the haptic device which is static. Greater fidelity, transparency, more stability and also no need to large actuators are of the advantages of this system. In this project, first we present a new...