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Engineering of mature human induced pluripotent stem cell-derived cardiomyocytes using substrates with multiscale topography
, Article Advanced Functional Materials ; Volume 28, Issue 19 , 2018 ; 1616301X (ISSN) ; Garbern, J. C ; Behzadi, S ; Hill, M. J ; Tresback, J. S ; Heydari, T ; Ejtehadi, M. R ; Ahmed, N ; Copley, E ; Aghaverdi, H ; Lee, R. T ; Farokhzad, O. C ; Mahmoudi, M ; Sharif University of Technology
Wiley-VCH Verlag
2018
Abstract
Producing mature and functional cardiomyocytes (CMs) by in vitro differentiation of induced pluripotent stem cells (iPSCs) using only biochemical cues is challenging. To mimic the biophysical and biomechanical complexity of the native in vivo environment during the differentiation and maturation process, polydimethylsiloxane substrates with 3D topography at the micrometer and sub-micrometer levels are developed and used as cell-culture substrates. The results show that while cylindrical patterns on the substrates resembling mature CMs enhance the maturation of iPSC-derived CMs, sub-micrometer-level topographical features derived by imprinting primary human CMs further accelerate both the...
The influence of annealing temperature on the graphitisation of CK 45 steel
, Article Journal of Alloys and Compounds ; Volume 475, Issue 1-2 , 2009 , Pages 822-826 ; 09258388 (ISSN) ; Issa Abadi Bozchalooi, G ; Azzat pour, H. R ; Sharif University of Technology
2009
Abstract
Graphitization in steels is a subject which has been studied temporarily in past decades. The importance of this phenomenon is due to the fact that graphite formation in steels can ease machining treatment and increase cold-work capability of steels. Weight reduction of the parts and the dedicated bioenvironmental properties of these steels are considered as a valuable replacement for lead containing steels for researchers. Anyway there has been always the assumption that this operation is long and not economically cost effective. For this reason due to the different conditions of applied heat treatments, the effects of the temperature and the time period of heat treatment on the...
Geometric optimization of a double pipe heat exchanger with combined vortex generator and twisted tape: A CFD and response surface methodology (RSM) study
, Article Thermal Science and Engineering Progress ; Volume 18 , 2020 ; Amiri, P ; Saffari Pour, M ; Sharif University of Technology
Elsevier Ltd
2020
Abstract
In this research, a numerical investigation is done on the effect of employing the new combined vortex generators, the twisted tape turbulator and Al2O3-H2O nanofluid as the involved base fluid. Such study is carried out on the behavior of the heat transfer rate and the pressure drop of a double pipe heat exchanger. Accordingly, the response surface methodology (RSM) grounded on the central composite design (CCD) is used for acquiring the optimized geometry of the combined vortex generator and twisted tape turbulator. In order to have the maximum Nusselt number and minimum friction factor, twenty cases with different pitches ratio Pil=0.09-0.18, angles (θ=0-30°) and Reynolds numbers (Re =...
Elimination of Signal Distortion Using Generative Adversarial Network
, M.Sc. Thesis Sharif University of Technology ; Bagheri Shouraki, Saeed (Supervisor) ; Pour Mohammad Namvar, Mehrzad (Supervisor)
Abstract
Nowadays millions of images are shared on social media every day , So image inpainting has become an important issue . After advent of Generative adversarial network image inpainting methodes based on deep learning has been revived and significant progress has been made . For a proper image inpainting , The inpainted image must benefit from the appropriate structure and texture in the missing regions . Therefore, in this project , an attempt is made to use a two-stage structure by using Generative adversarial network .in first stage first by using Gabor filters , the image structure is extracted and then the image structure is completed , while the second stage focuses only on the...
Simplified model predictive current control of four-level nested neutral point clamped converter
, Article Sustainability (Switzerland) ; Volume 15, Issue 2 , 2023 ; 20711050 (ISSN) ; Hassan, M ; Bilal Shahid, M ; Mudassir Munir, H ; Saeed, M. S. R ; Shahzad, M ; Isik, S ; Alharbi, M ; Sharif University of Technology
Multidisciplinary Digital Publishing Institute (MDPI)
2023
Abstract
Model predictive control (MPC) is an efficient and growing approach to power converter control. This paper proposes an improved and simplified model predictive current control (MPCC) technique for a four-level nested neutral point clamped (4L-NNPC) converter. Conventional MPCC exhibits better performances as compared to the conventional linear control system such as fast dynamic response, consideration of the system constraints, and nonlinearities. However, the application of the conventional model predictive current control (MPCC) approach on complex systems provokes a significant number of calculations, which is the main hurdle to its practical implementation. To fix this flaw, this paper...
Recent advances in spatial analog optical computing
, Article 5th International Conference on Millimeter-Wave and Terahertz Technologies, MMWaTT 2018, 18 December 2018 through 20 December 2018 ; Volume 2018-December , 2019 , Pages 6-11 ; 21570965 (ISSN); 9781538677179 (ISBN) ; Karimi, P ; Khavasi, A ; Sharif University of Technology
Institute of Electrical and Electronics Engineers Inc
2019
Abstract
Traditional analog computers that perform mathematical operations electronically or mechanically suffer from their relatively large size and slow response. Recently, the idea of spatial analog optical computing has overcome these restrictions. The different techniques to implement spatial analog optical computation can be categorized into two fundamental approaches: (I) metasurface (MS) approach and (II) Green's function (GF) approach. In the first approach, a metasurface is designed to implement the Green's function of the desired operator in the spatial domain. This means that this approach needs two sub-blocks to perform Fourier and inverse Fourier transform. On the other hand, in the...
Design and Characterization of Silica based Mud for Shale Drilling
, M.Sc. Thesis Sharif University of Technology ; Ramezani Saadat Abadi, Ahmad (Supervisor) ; Jamshidi, Saeed (Supervisor)
Abstract
Constant drilling in the shale formation causes many problems such as shale swelling and well instability. Annually many costs are spent dealing with these problems in the drilling industry. Many factors can affect this issue. The most important factor is the type of drilling fluid and its additives. The use of oil-based mud is the best option to deal with the clays instability but, due to environmental problems resulting from OBM, their use has been banned in most parts of the world. Therefore, the water-based mud is the only option for the oil industry that can modify its property by use of additives. In this study, the muds contain Nano silica have been introduced. Silicate as shale...
Effects of magnetoelastic loads on free vibration characteristics of the magnetorheological-based sandwich beam
, Article Journal of Intelligent Material Systems and Structures ; Volume 31, Issue 7 , 2020 , Pages 1015-1028 ; Shahali, P ; Haddadpour, H ; Sharif University of Technology
SAGE Publications Ltd
2020
Abstract
In this contribution, we have investigated the effects of magnetoelastic loads on free vibration characteristics of the magnetorheological-based sandwich beam. The considered sandwich beam consists of a magnetorheological core with elastic top and base layers. For these means, the structural governing equations are derived using the Hamilton principle and solved by the finite element method. The results are validated in comparison with the existing results in the literature. The effects of variation in the parameters such as magnetic field intensity and the thickness of the core and top layers on the deviation of the first natural frequency and the corresponding loss factor are studied as...
Regularity of Area-Minimizing Currents
, M.Sc. Thesis Sharif University of Technology ; Safdari, Mohammad (Supervisor)
Abstract
This research introduces temperature measurement by a non-intrusive pyrometric method of the ratio of two colors of soot. For pyrometry, the spectral sensitivity of the Nikon D7100 camera was obtained by developing a neural network based on the results of photographing colored papers and their spectrum, and this camera was used for temperature measurement. Based on the dependence of soot radiation on temperature and the spectral sensitivity of the camera, a calibration chart has been extracted on the ratio of the green channel to the red channel of the camera with the soot temperature, which is used to produce the temperature contour using the flame image. The temperature contour of...
Experimental and Numerical Study of Pulse Shaper Geometry Effects in Split Hopkinson Pressure Bar Test
,
M.Sc. Thesis
Sharif University of Technology
;
Naghdabadi, Reza
(Supervisor)
;
Sohrabpour, Saeed
(Supervisor)
Abstract
Split Hopkinson pressure bar (SHPB) test is one of the tests used for characterizing the mechanical behavior of materials at high strain rates between and s -1. A SHPB test consists of a gas gun, a striker bar, an incident bar, a transmission bar and a specimen which is sandwiched between the incident and transmission bars. In order to achieve constant strain rate during the test which is necessary in SHPB test, the incident pulse should obey the stress-strain curve of the specimen. For shaping the incident pulse usually a thin deformable disk -called pulse shaper- is placed between the striker and incident bars. In this thesis, first we designed, implemented and calibrated the measuring...
Effect of thrust on the aeroelastic instability of a composite swept wing with two engines in subsonic compressible flow
, Article Journal of Fluids and Structures ; Volume 36 , 2013 , Pages 18-31 ; 08899746 (ISSN) ; Askarian, A. R ; Zarifian, P ; Sharif University of Technology
2013
Abstract
This paper aims to investigate aeroelastic stability boundary of subsonic wings under the effect of thrust of two engines. The wing structure is modeled as a tapered composite box-beam. Moreover, an indicial function based model is used to calculate the unsteady lift and moment distribution along the wing span in subsonic compressible flow. The two jet engines mounted on the wing are modeled as concentrated masses and the effect of thrust of each engine is applied as a follower force. Using Hamilton's principle along with Galerkin's method, the governing equations of motion are derived, then the obtained equations are solved in frequency domain using the K-method and the aeroelastic...
Optimization of nonlinear unbalanced flexible rotating shaft passing through critical speeds
, Article International Journal of Structural Stability and Dynamics ; Volume 22, Issue 1 , 2022 ; 02194554 (ISSN) ; Rokn Abadi, M ; Firouz Abadi, R. D ; Sharif University of Technology
World Scientific
2022
Abstract
This work studies the nonlinear oscillations of an elastic rotating shaft with acceleration to pass through the critical speeds. A mathematical model incorporating the Von-Karman higher-order deformations in bending is developed to investigate the nonlinear dynamics of rotors. A flexible shaft on flexible bearings with springs and dampers is considered as rotor system for this work. The shaft is modeled as a beam and the Euler-Bernoulli beam theory is applied. The kinetic and strain energies of the rotor system are derived and Lagrange method is then applied to obtain the coupled nonlinear differential equations of motion for 6 degrees of freedom. In order to solve these equations...
Nonlinear responses of unbalanced flexible rotating shaft passing through critical speeds
, Article Meccanica ; 2021 ; 00256455 (ISSN) ; Rokn Abadi, M ; Firouz Abadi, R.D ; Mehralian, F ; Sharif University of Technology
Springer Science and Business Media B.V
2021
Abstract
This work studies the nonlinear oscillations of an elastic rotating shaft with acceleration to pass through the critical speeds. A mathematical model incorporating the Von-Karman higher-order deformations in bending is developed and analyzed to investigate the nonlinear dynamics of rotors. A flexible shaft on flexible bearings with springs and dampers is considered as rotor system for the present work. The shaft is modeled as a beam with a circular cross-section and the Euler Bernoulli beam theory is applied. The kinetic and strain energies of the rotor system are derived and Lagrange method is then applied to obtain the coupled nonlinear differential equations of motion for 6° of freedom....
Synthesis of tin oxide nanoparticles in order to study its properties
, Article Digest Journal of Nanomaterials and Biostructures ; Volume 16, Issue 1 , 2021 , Pages 41-49 ; 18423582 (ISSN) ; Ali, N ; Shahid, A ; Khan, S ; Alrobei, H ; Sharif University of Technology
S.C. Virtual Company of Phisics S.R.L
2021
Abstract
Pure tin oxide nanoparticles ware synthesized via Co-precipitation method. The as-synthesized nanoparticles were characterized by Fourier transform infrared spectroscopy (FTIR), thermo-gravimetric analysis (TGA), X-ray diffraction (XRD) and diffuse reflectance spectroscopy (DRS). X-ray diffraction shows that tetrahedral shaped nanoparticles of crystallite size 47.35nm were prepared successfully. The crystallinity was established due the reduction in distortion ratio and dislocation density. The value of strain showed that the nanoparticles fabricated were of high stability. The direct and indirect optical band gap of as-synthesized SnO2 nanoparticles were determined from the reflectance...
Nonlinear responses of unbalanced flexible rotating shaft passing through critical speeds
, Article Meccanica ; Volume 57, Issue 1 , 2022 , Pages 193-212 ; 00256455 (ISSN) ; Rokn Abadi, M ; Firouz Abadi, R. D ; Mehralian, F ; Sharif University of Technology
Springer Science and Business Media B.V
2022
Abstract
This work studies the nonlinear oscillations of an elastic rotating shaft with acceleration to pass through the critical speeds. A mathematical model incorporating the Von-Karman higher-order deformations in bending is developed and analyzed to investigate the nonlinear dynamics of rotors. A flexible shaft on flexible bearings with springs and dampers is considered as rotor system for the present work. The shaft is modeled as a beam with a circular cross-section and the Euler Bernoulli beam theory is applied. The kinetic and strain energies of the rotor system are derived and Lagrange method is then applied to obtain the coupled nonlinear differential equations of motion for 6° of freedom....
Numerical investigation of thermal performance augmentation of nanofluid flow in microchannel heat sinks by using of novel nozzle structure: sinusoidal cavities and rectangular ribs
, Article Journal of the Brazilian Society of Mechanical Sciences and Engineering ; Volume 41, Issue 10 , 2019 ; 16785878 (ISSN) ; Akbari, O. A ; Toghraie, D ; Pour, M. S ; Jönsson, P. G ; Ersson, M ; Sharif University of Technology
Springer Verlag
2019
Abstract
In this paper, we present a numerical simulation of a laminar, steady and Newtonian flow of f-graphene nanoplatelet/water nanofluid in a new microchannel design with factors for increasing heat transfer such as presence of ribs, curves to enable satisfactory fluid mixing and changing fluid course at the inlet and exit sections. The results of this study show that Nusselt number is dependent on nanoparticles concentration, inlet geometry and Reynolds number. As the nanofluid concentration increases from 0 to 0.1% and Reynolds number from 50 to 1000, the Nusselt number enhances nearly up to 3% for increase in fluid concentration and averagely from 15.45 to 54.1 and from 14.5 to 55.9 for...
Stable trans isomer as the kinetic and theromodynamic product for the oxidative addition of MeI to cycloplatinated(II) complexes comprising isocyanide ligands
, Article Applied Organometallic Chemistry ; Volume 32, Issue 4 , 2018 ; 02682605 (ISSN) ; Babadi Aghakhanpour, R ; Hossein Abadi, M ; Kia, R ; Raithby, P. R ; Sharif University of Technology
John Wiley and Sons Ltd
2018
Abstract
The present investigation introduces a new series of cycloplatinated(II) complexes, with the general formula Pt(O-bpy)(Me)(CN-R)] (R = benzyl, 2-naphtyl and tert-butyl), which are able to generate the stable trans-Pt(IV) product in the solution after the reaction with iodomethane. In fact, the trans product is both the kinetic and thermodynamic product of the reaction; this observation was supported by DFT calculations. These Pt(II) complexes are supported by 2,2'-bipyridine N-oxide (O-bpy) and one of several isocyanides as the cyclometalated and ancillary ligands, respectively. These new Pt(II) complexes undergo oxidative addition with MeI to give the corresponding trans-Pt(IV) complexes....
Observation of cosmic rays by Alborz -1 array
, Article Iranian Journal of Physics Research ; Volume 17, Issue 3 , 2017 , Pages 473-484 ; 16826957 (ISSN) ; Sharif University of Technology
Isfahan University of Technology
2017
Abstract
The first phase of the Alborz Observatory Array (Alborz-1) consists of 20 plastic scintillation detectors each one with surface area of 0.25 m2 spread over an area of 40×40 m2 realized to the study of Extensive Air Showers around the knee at the Sharif University of Technology campus. The first stage of the project including construction and operation of a prototype system has now been completed and the electronics that will be used in the array instrument has been tested under field conditions. In order to achieve a realistic estimate of the array performance, a large number of simulated CORSIKA showers have been used. In the present work, theoretical results obtained in the study of...
Prediction and Compensation of Intraoperative Brain Shift Using Biomechanical Modeling
, M.Sc. Thesis Sharif University of Technology ; Farahmand, Farzam (Supervisor)
Abstract
The human brain is the most sensitive and important human organ and surgery must be done with high precision and without risk. During surgery, brain tissue deform continuously due to gravity, out of the cerebrospinal fluid and the changing pressure of the cerebrospinal fluid and the surgical maneuvers. Because the surgeon has no direct view on brain internal, the ways to solve this problem is to pay attention. This method makes it possible to the surgeon see in the brain and the brain tissue deformation. This thesis method is based on biomechanical modeling. After forming finite element model from the pre-operative MRI, brain surface and volume datasets during surgery as a load, apply to the...
Natural frequencies of C60, C70, and C80 fullerenes
, Article Applied Physics Letters ; Volume 96, Issue 2 , 2010 ; 00036951 (ISSN) ; Vafai, A ; Sharif University of Technology
2010
Abstract
This letter adopts an atomistic modeling approach to study free vibrational characteristics of C60, C70, and C80 fullerenes. In this regard, we use the molecular structural mechanics consisting of equivalent structural beams to calculate the nonzero natural frequencies. The simulation results indicate that the first natural frequency of the fullerene is in the order terahertz and decreases nonlinearly with respect to the number of the carbon atoms