Sharif Digital Repository

Dissimilar Al/Cu joints were produced through simple cold compression technique. The influence of different reductions (40, 53 and 66 %) on the joint strength was studied. Also, the effect of heat treatment on the joints’ mechanical characteristics was investigated using a modified miniature shear test. Microscopical examinations by means of optical and scanning electron microscopes were conducted and results confirmed that acceptable joints produced through 53 and 66 % deformations. According to the shear test results, it was revealed that post-weld heat treatment influenced the joint’s strength and caused strength enhancement in the samples which were not subjected to annealing prior to... 

Surface tension driven passive micro-pumping relies mainly on the surface tension properties. To have control over surface tension driven passive micro-pumps (STD-PMPs), it is essential to understand the physical background of the fluid flow in these pumps. Hence, the purpose of this work is to give an exploration of the flow physics of a STD-PMP. In this regard, computer simulation is used to give detailed information about the flow pattern and physical phenomena at different conditions. To this end, a droplet of water, with a specified diameter, is placed onto an entry port connected to another droplet at the exit port via a microchannel. The results indicate that the pumping process, in... 

In this paper, we propose a two dimensional optimal linear detector (2-D OLD) for slowly fluctuating target in Gaussian interference. We assume that the samples of received signal in the range and in the successive pulsation times are collected in a two dimensional array. In conventional detectors, each column of this matrix (the Samples of the same pulsation time) is detected separately and the binary results may be integrated for successive pulsation times in order to improve the detection performance. In fact, by applying binary integration, we ignore the considerable correlation among 2-D data in the azimuth direction. In the proposed 2-D OLD detector, this correlation is considered,... 

In this paper, implosion of a micron-sized air bubble was studied numerically using OpenFoam software package. Then a parametric investigation on the flow physics of the problem was performed. The results show that as the initial pressure of the liquid increases, the pressure and the temperature inside the bubble increases such that in some cases, the temperature is as high as the one required for luminescence. Also, increasing the density and the temperature of the liquid solely, decreases the intensity of the collapse. © 2018  

In this paper, we evaluate the capacity of Multiple-Input Multiple-Output (MIMO) systems using directional antennas in non-isotropic scattering environments. Our analytical analysis approach results in closed-form approximate formulas in low Signal to Noise Ratio (SNR) regime (in contrast to previous research works which have investigated the same problem by employing experimental or simulation frameworks). We propose an upper bound for the introduced approximate error. Our results show that MIMO systems equipped with directional antennas may have much higher capacity in nonisotropic scattering environments compared to MIMO systems equipped with omni-directional antennas. We also evaluate... 

This paper addresses dynamic cell formation problem (DCFP) which has been explored vastly for several years. Although a considerable body of literature in this filed, two remarkable aspects have been significantly ignored so far, as uncertainty and human-related issues. In order to compensate such a shortage, this paper develops a bi-objective stochastic model. The first objective function of the developed model seeks to minimize total cost of machine procurement, machine relocation, inter-cell moves, overtime utilization, worker hiring/laying-off, and worker moves between cells; while the second objective function maximizes labor utilization of the cellular manufacturing system. In the... 

In this paper, trace locality of reference (LoR) is identified as a mechanism to predict the behavior of a variety of systems. If two objects were accessed nearby in the past and the first one is accessed again, trace LoR predicts that the second one will be accessed in near future. To capture trace LoR, trace graph is introduced. Although trace LoR can be observed in a variety of systems, but the focus of this paper is to characterize it for data accesses in memory management systems. In this field, it is compared with recency-based prediction (LRU stack) and it is shown that not only the model is much simpler, but also it outperforms recency-based prediction in all cases. The paper... 

It is now known that at least 10% of samples with pancreatic cancers (PC) contain a causative mutation in the known susceptibility genes, suggesting the importance of identifying cancer-associated genes that carry the causative mutations in high-risk individuals for early detection of PC. In this study, we develop a statistical pipeline using a new concept, called gene-motif, that utilizes both mutated genes and mutational processes to identify 4211 3-nucleotide PC-associated gene-motifs within 203 significantly mutated genes in PC. Using these gene-motifs as distinguishable features for pancreatic cancer subtyping results in identifying five PC subtypes with distinguishable phenotypes and... 

This paper has been prepared, based on reports regarding extraordinary induced ac voltage on buried gas pipelines in residential and industrial areas of the capital city of Tehran, especially in densely populated central areas. Also, some reports are considered on the existence of ac induced voltage in buried gas pipelines under the overhead transmission lines, for example, one case located 80 Km to the west of Tehran, in an agricultural region of the town of Abyek. In this paper, the results of an extensive theoretical, experimental and practical investigation and implementation of methods carried out during the last two years are introduced. Furthermore, this paper includes evaluation of... 

The axial turbine is one of the most challenging components of gas turbines for industrial and aerospace applications. With the ever-increasing requirement for high-aerodynamic performance blades, three-dimensional aerodynamic shape optimization is of great importance. In this research, the rear part of a gas turbine consisting of a one-stage axial turbine is optimized numerically. A useful optimization algorithm is presented to improve the efficiency and/or pressure ratio of the axial turbine with two different objective functions. The three-dimensional blade-shape optimization is employed to study the effects of the turbine stator and rotor lean and sweep angles on the turbine performance.... 

A high quality joint of zinc based pressure die cast alloys can be hardly achieved by conventional fusion welding. In this study, a novel technique to achieve the globular weld structure using stirring the localized semisolid zone during butt joining of Zamak-3 pressure die cast alloy is proposed and effect of welding parameters on mechanical and microstructural properties are investigated. A gas heating system was designed to heat up the nitrogen gas to desired temperature accurately to create a localized semisolid pool. At this stage a fine stirrer was introduced into the weld seam in order to mix the two sides into a single uniform joint. By presented process, globular microstructure of... 

The human protein disulfide isomerase (hPDI), is an essential four-domain multifunctional enzyme. As a result of disulfide shuffling in its terminal domains, hPDI exists in two oxidation states with different conformational preferences which are important for substrate binding and functional activities. Here, we address the redox-dependent conformational dynamics of hPDI through molecular dynamics (MD) simulations. Collective domain motions are identified by the principal component analysis of MD trajectories and redox-dependent opening-closing structure variations are highlighted on projected free energy landscapes. Then, important structural features that exhibit considerable differences... 

Background MicroRNAs (miRNAs) are frequently deregulated in various types of cancer. While antisense oligonucleotides are used to block oncomiRs, delivery of tumour-suppressive miRNAs holds great potential as a potent anti-cancer strategy. Here, we aim to determine, and functionally analyse, miRNAs that are lowly expressed in various types of tumour but abundantly expressed in multiple normal tissues. Methods The miRNA sequencing data of 14 cancer types were downloaded from the TCGA dataset. Significant differences in miRNA expression between tumor and normal samples were calculated using limma package (R programming). An adjusted p value < 0.05 was used to compare normal versus tumor miRNA... 

As noteworthy properties of amine aqueous solutions, the densities and viscosities of aqueous N-Methyldiethanolamine (MDEA) solutions and mixtures of MDEA with 2-Amino-2-methyl-1-propanol (AMP), Diisopropanolamine (DIPA), Monoethanolamine (MEA), and Diethanolamine (DEA) were estimated under CO2 gas loading using Adaptive Neuro-Fuzzy Inference System (ANFIS), Multi-Layer Perceptron Artificial Neural Network (MLPANN), Support Vector Machine (SVM), and Least Square Support Vector Machine (LSSVM). The density and viscosity were estimated as a function of temperature, CO2 loading, pressure, and molecular weight of mixtures. In this regard, the actual data points were collected from the...