Sharif Digital Repository

In this thesis, a multi-stage project portfolio selection and scheduling problem in an uncertain environment is modeled, analyzed and solved. Moreover, we investigate the situations in which a project manager is confronted to a large number of projects to be selected and scheduled while the required resources of the projects are limited and renewable. The aim is to maximize objective function which is the net present value of the profit of the projects. To solve the mentioned problem, we introduce a multi-stage stochastic programming. For the reason that, in real problems, optimization problems that included all restraints are large scale and have computational complexity, these problems are... 

Profile Monitoring is a new research topics in the field of statistical process control. In many applications of statistical quality control, sometimes quality of a process or product described by a relationship between a response variable and one or more independent variables.The researchers call this relationship profile. The study seeks to demonstrate that monitoring profiles In addition, the industry can be effective in medical field and improves control of the patient's condition by a doctor. Profiles are usually modeled with a linear regression equation, non-linear or polynomial. finally, the results of this study, using actual data, models and methods to predict and control... 

As a method of cancer treatment or improvement of cancer-related complications, external radiation therapy is prescribed by physicians, in case of detection of a tumor in a region of patient’s body. Over time, various techniques have been developed for external beam radiation therapy. Among which, Intensity Modulated Radiation Therapy (IMRT), due to its ability to adjust the intensity of radiation beams, has a higher capacity to generate appropriate dose distribution based on tumor size and volume and it is one of the most widely used techniques in cancer treatment centers.The core process in treatment planning is using appropriate computer algorithms which results in posing enough damage to... 

The aim of Emergency Medical Services (EMS) is to provide fast medical care and to transport patients to hospitals at the earliest possible time, so as to reduce injury and fatality rate. Healthcare managers try to improve healthcare systems by reducing the response time to demands. In this thesis, we present mathematical models for the problem of location and relocation of emergency vehicles after the end of their service time or after they have returned to a hospital. We believe that implementing these models can help managers improve the performance of emergency medical services. In the first part of this study, we present a two-level deterministic optimization model considering demand... 

At the present, End-stage renal disease(ESRD) is the ninth-leading cause of death in the USA.according methods of medical treatment for End-stage renal disease (ESRD), transplantation is the most viable renal replacement therapy for ESRD patients, there is a disparity between the demand for kidneys for transplantion and the supply. Incompatible inblood-type and antigen matching between patient-donor pairs is cause of shortage in disparity between the demand and the supply.paired kidney exchange of kidney among incompatible patient-donor pairs.PKE can be solve many difficulties in matching patient with incompatible donors. Kidney transplant surgeries in PKE must take place simultaneously... 

Operating rooms have always been the most expensive and also the most profitable section in hospitals which include approximately one third of cost and two third of income. The management always wants to decrease the cost of hospitals. On the other hand, usually this goal stands against other goals such as patient’s satisfaction. So the manager should make a balance between these goals. In this research, we will propose an integer programming model for operating room scheduling problem without uncertainty for elective patients. In order to make the model more realistic, we want to make connection between operating room theatre and intensive care units. Also, we will consider desirable...