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Mesoporous silica nanoparticles (MCM-41) coated PEGylated chitosan as a pH-Responsive nanocarrier for triggered release of erythromycin [electronic resource]
, Article International Journal of Polymeric Materials and Polymeric Biomaterials ; 2014, Volume 63, Issue 13, Pages 692-697 ; Mazaheri Tehrani, Zahra ; Sharif University of Technology
Abstract
A pH-responsive drug delivery system based on core shell structure of mesoporous silica nanoparticle (MSN) and chitosan-PEG copolymer was prepared and characterized by Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), scanning electron microscope (SEM), and high-resolution transmission microscope (HR-TEM) techniques. In order to improve compatibility MSN and drug, mesoporous nanosilica was modified by 3-aminopropyl triethoxysilane. The release of erythromycin (a macrolide antibiotic) as a model drug was investigated in two pHs, 7.4 and 5.5
Using Nonlinear Effects of Light for Optical Signal Processing
, M.Sc. Thesis Sharif University of Technology ; Kavehvash, Zahra (Supervisor)
Abstract
Ultrafast signal processing in time-domain with high resolution and reconfigura-bility is a challenging task. This paper, for the first time, introduces a time-varying metasurface consisting of graphene microribbon array for implementing time-lens in the terahertz domain. Given that the surface conductivity of graphene is proportional to the Fermi energy level in the THz regime, it is possible to change the phase property of the incident electromagnetic pulse by changing the Fermi level while the Fermi level itself is a function of voltage. Upon this fact, a quadratic temporal phase modulator, namely time-lens has been realized. This phase modulation is applied to the impinging signal in the...
Theoretical and Computational Investigation of Quantum Plasmonic Properties of Nanocluster Dimers
, M.Sc. Thesis Sharif University of Technology ; Jamshidi, Zahra (Supervisor)
Abstract
In today's era, metal nanoparticles play an important role in technologies emerging from different sciences, such as chemistry, physics, optics, material science, due to their unique characteristics. In the development of nanooptics science, it can be said that metal nanoparticles play an important role. The ability of conductive electrons collective oscillation causes surface charge density fluctuations in nanoparticles, this phenomenon is known as surface plasmons. Surface plasmons are surprisingly coupled with light and cause the significant increase in the intensity of optical fields induced in nanoparticles. Therefore, with the presence of localized surface plasmons or plasmon...
Theoretical Investigation of Ab-initio MD Approach to Increase the Efficiency and Accuracy of VCD Spectrum Calculation
, M.Sc. Thesis Sharif University of Technology ; Jamshidi, Zahra (Supervisor)
Abstract
Understanding of the Molecules is the main purpose of the chemistry. Ab-initio molecular dynamics (AIMD) as a branch of the computational chemistry, tries to give us a deep comprehension of the molecule, and its chemical, physical and optical activities. This comprehension, relies on the accuracy of quantum mechanics, in addition to the speed of the classical mechanics. The mixing of the quantum mechanics and the classical mechanics could simulate activities of the atoms in the time-domain, provided the mixing is done with precaution. This, in turn, helps us to forecast the response of a molecule in different situations, and also translating the macroscopic phenomena in a nanoscopic...
Investigation of Plasmonic Excitation in Carbonic Nanostructures Within Near-IR
, M.Sc. Thesis Sharif University of Technology ; Jamshidi, Zahra (Supervisor)
Abstract
To date, the plasmonic properties of many metallic and semi-conducting materials have been investigated and used in various industries. One of the plasmonic material categories that have always been considered is polycyclic aromatic hydrocarbon or PAH, whose plasmonic resonance energy depends on the charge state of the molecule. In this regard, it is easy to change the plasmonic resonance energy via changing the induced charge, which is a unique feature of the mentioned materials. In addition, plasmonic structures with excitations in the infrared region are able to enhance the vibration intensity of absorbed molecules by increasing the electric field around themselves. Therefore, they have...
Using Simulation-Optimization Approach for Fire Station Location and Vehicle Assignment Problem: a Case Study in Tehran, Iran
, M.Sc. Thesis Sharif University of Technology ; Amini, Zahra (Supervisor)
Abstract
In this research, the problem of locating fire stations and allocating equipment has been studied and a simulation-optimization approach has been presented to solve the problem. The mathematical models of this research were developed based on the idea of the randomness of the covered demand and the maximum expected coverage model. In these models, the issue of non-availability of equipment to cover accidents, the random nature of accidents, various fire incidents and the equipment needed to cover them are considered. Two mathematical models with deterministic and non-deterministic approach with different scenarios for demand are proposed. The non-deterministic model is developed with the aim...
Introducing An Integrated Framework For Solving The Fleet Planning Problem Using A Simulation-Optimization Approach
, M.Sc. Thesis Sharif University of Technology ; Amini, Zahra (Supervisor)
Abstract
One of the main concerns of industrial companies’ managers is providing an efficient logistics system. To achieve an efficient logistics system, the fleet planning problem is studied by many researchers in recent years. This problem consists of multiple sub-problems at three levels: operational, tactical, and strategic. These sub-problems are closely related to each other and need to be studied and addressed in an integrated manner. In this research, an attempt is made to provide an integrated framework to solve the vehicle routing problem (operational), outsourcing problem (tactical), and fleet composition problem (strategic). These problems have various uncertainties, including customer...
Evaluation of the Behaviorof Earth and Rockfill Dams during Construction and First Impounding using Instrumentation data and Numerical Modeling (Case Study: Dam Gavoshan)
, M.Sc. Thesis Sharif University of Technology ; Haeri, Mohsen (Supervisor)
Abstract
Monitoring is of particular importance after impounding and during dam operation. In all large dams, by installation of the required instruments the pore pressure, soil mass pressure and displacement during construction, first impounding and operation are measured, then the performance of dam will be analyzed and evaluated. The aim of this study is to evaluate the performance of the "Gavoshan" dam, which has an important role on agriculture development and drinking water supply at west part of Country. To reach this, the values resulting from instruments have been implemented by FLAC software, using "Back Analysis" method. However, this assessment is complete when "back analysis" method is...
Joint Pricing and Inventory Control of Deteriorating Items under Conditions of Finite Production, Partial Backlogging and Lost Sale
, M.Sc. Thesis Sharif University of Technology ; Haji, Alireza (Supervisor)
Abstract
When demand for a product is price sensitive, pricing and lot sizing decisions are interdependent. Similarly, when a product is highly perishable, the demand may need to be backlogged to avoid costs due to deterioration, i.e., perishability and backlogging are complementary conditions.In this thesis we stablish two economic production quantity models for deteriorating items under conditions of finite production, exponential decay and partial backordering and lost sale. Two joint pricing inventory control models are developed for the problem by employing different modeling approaches over an infinite planning horizon. In two models, customer is viewed to be impatient and the fraction of the...
Visual Simultaneous Localization and Mapping using an RGB-D Camera
, M.Sc. Thesis Sharif University of Technology ; Kasaei, Shohreh (Supervisor)
Abstract
Simultaneous localization and mapping (SLAM) is the action of detecting robot pose in an unknown environment and building the environment map by use of input data that captured from robot sensors. In visual SLAM, the input data for the robot, is limited to camera sensors. Nowadays, SLAM is one of the main challenges in robotic research.For autonomous action, we need robot pose in the map of the environment. The map production in the indoor environment, there is no GPS data, is one of the research issue in robotic community, in last decade. In this thesis, a new and efficient method is proposed for SLAM at the level of objects. The maps produced by state of the art methods don’t have a...
Numerical Investigation on Oil/Water Separation through Coalescence in Membrane Pores
, M.Sc. Thesis Sharif University of Technology ; Moosavi, Ali (Supervisor)
Abstract
Oil/water separation is an important field, not only for scientific research, but also for environmental, economic, and social issues. On the one hand, oily wastewater, resulting from industries such as steel, aluminum, food, textile, leather, petrochemical and metal finishing, has become the most common pollutant all over the world. On the other hand, frequent oil spill accidents are of great concern since the discharge can lead not only to serious environmental pollution, but also a great loss of energy.
In crude oil removing water is necessary due to reducing corrosion, increasing thermal values of fuels obtained from crude oil, preventing catalists from destruction by water and...
In crude oil removing water is necessary due to reducing corrosion, increasing thermal values of fuels obtained from crude oil, preventing catalists from destruction by water and...
Feasibility Study of Improving the Quality of PEM Images by Considering TOF and the DOI Correction
, M.Sc. Thesis Sharif University of Technology ; Hosseini, Abolfazle (Supervisor)
Abstract
Breast cancer is the most common type of cancer in women and the second cause of death among them. The chance of successful treatment would be significantly increased if the disease is diagnosed at its early stages. There are numerous methods to diagnose breast cancer. One of the most important methods is positron emission mammography (PEM).The main aim of this study is to investigate the feasibility of improving PEM images by considering the time of flight corrections and the penetration depth of the rays in the crystals.In this study, a commercial PEM system, Naviscan PEM, is simulated using the GATE software. In the first phase of the study, two opposing planar detectors are used to study...
Improving Speech-to-Speech Translation in Audio Dubbing Systems
, M.Sc. Thesis Sharif University of Technology ; Sameti, Hossein (Supervisor)
Abstract
Direct speech-to-speech translation, in which all compontents are trained jointly, is advantageous over cascaded approaches, because this method employs a simple yet effective pipeline to produce the outputs with a little inference time. Direct speech-to-speech translation models suffer from data scarcity issue, because they need parallel speech data in source and target languages. In this thesis, we present a novel direct speech-to-speech translation model to translate Persian speech to English, which is based on discrete speech units and uses a conformer-based encoder which is pretrained and a transformer-based causal decoder which uses relative position multi-head attention to do the task...
Analytical Modelling and Optimization of Disk Type, Slot Less Resolver
, M.Sc. Thesis Sharif University of Technology ; Nasiri Gheidari, Zahra (Supervisor)
Abstract
Resolvers, due to their robust structure, are widely used in automation systems. Among the types of resolvers, the accuracy of the Wound Rotor (WR) resolver in the occurrence of common mechanical errors is higher than other types of resolvers. therefore, in this thesis, an AFWRR is studied to improve the performance. Increasing the number of poles in WR resolvers is a good solution for increasing the accuracy of these electromagnetic position sensors. However, high-speed WR resolvers due to employing fractional slot windings suffer from rich sub-harmonics in the induced voltages. A common solution for suppressing the undesirable sub-harmonics is using multi-layer winding with appropriate...
A Survey on Searchable Symmetric Encryption Schemes
, M.Sc. Thesis Sharif University of Technology ; Khazaei, Shahram (Supervisor)
Abstract
Using “Searchable Encryption” enables us to encrypt the data, while preserving the possibility of running search queries. One of the most important applications of the mentioned is in Cloud Storage. As users do not trust the Cloud space, they are not inclined to store their data on the Could. The solution to this problem is of course, Cryptography. However, ordinary Cryptography methods, eliminate the data’s searchability. Hence, we need encryption schemes that code the data while retaining their searchability. So far, various schemes has been proposed that differ in their performance, security level, and usage. In this thesis, we aim to discuss and analyze these methods
Temporal Depth Imaging Based on Dispersion
, M.Sc. Thesis Sharif University of Technology ; Kavehvash, Zahra (Supervisor)
Abstract
In this thesis, the aim is designing an optical temporal imaging system. In recent years, due to many applications, including the receipt of high-rate data by slow receivers and compensation of dispersion in telecommunication systems, researchers have considered the topic of temporal imaging. This field of research is based on dispersion, electro-optical modulators or time lenses and space-time theory. By modeling dispersion properties as a depth dimension and taking ideas from three-dimensional spatial imaging systems we intended to increase the temporal resolution and depth of focus of the structure. We also present a novel technique for multiplexing and demultiplexing telecommunication...
Time Domain Optical Signal Processing Based on the Duality Between Dispersion and Diffraction
, M.Sc. Thesis Sharif University of Technology ; Kavehvash, Zahra (Supervisor)
Abstract
In the last decades, due to the growing demand of transferring information with high transmission rates, the complexity and development of telecommunication and optical systems is remarkable. Researchers around the world attempt to explore extraordinary potential of light to process information. In the mid-19th century, scientists discovered a mathematical symmetry between the spatial and temporal optics fields, which originated from the similarity of equations governing the paraxial diffraction of beams and the dispersion of narrow-band pulses known as space– time duality in scientific texts. This new approach provides more advanced and potent methods to temporal processing and...
Improving the Stability of an Urban Traffic Network with Limited Data by Using Percolation Theory and Dynamic Clustering
, M.Sc. Thesis Sharif University of Technology ; Amini, Zahra (Supervisor)
Abstract
One of the most vital aspects of understanding the traffic phenomenon is scrutinizing the traffic transition status, such as the transition from free flow to congestion. The Percolation Theory is a renowned theory focusing on analyzing various network types to detect the critical zones, which are the zones including links that are important to control to improve stability. By calculating the quality indices of network links, the Percolation Theory can simulate the traffic percolation propagation in the network and determine possible critical zones for further analysis. Most studies in this field assume access to data of several traffic parameters for the entire transportation network, such...
Modification of Biomedical Imaging Methods in Short Wavelength Infrared Window
, Ph.D. Dissertation Sharif University of Technology ; Kavehvash, Zahra (Supervisor)
Abstract
In recent years, optical biomedical imaging techniques show great potential in noninvasive imaging. Although these methods have many advantages over other biomedical imaging methods (such as Computerized Tomography (CT), Magnetic Resonance Imaging (MRI) and etc.), these techniques confront with some problems such as optical scattering, light absorption and etc. For in vivo imaging, the short-wavelength infrared region (SWIR; 1,000–2,000 nm) provides several advantages over the visible and near-infrared regions: general lack of auto-fluorescence, low light absorption by blood and tissue, and reduced scattering. In this thesis we want to analyze the traditional IR imaging techniques and...
Upgrading the Ultrasound Imaging System Based on The Implementation of the Strain Imaging Mode
, M.Sc. Thesis Sharif University of Technology ; Kavehvash, Zahra (Supervisor)
Abstract
Strain imaging is a non-invasive ultrasound modality for assessing cardiac function in echocardiography systems. In this thesis, we implemented a fully automated strain imaging system containing 5 steps: 1) echocardiographic view recognition, 2) cardiac cycle phase detection, i.e., the events of end-diastole (ED) and end-systole (ES), 3) segmentation of left ventricular (LV) myocardium, 4) motion estimation of this wall and 5) strain calculation. In this work, we propose a novel deep learning-based framework for phase detection of cardiac cycle by the use of echocardiographic images in multibeat videos. Further, by applying the augmentation technique, the model has been able to detect events...