Sharif Digital Repository

In static PET/CT imaging, the Standardized Uptake Value (SUV) parameter is used to evaluate diseases. The use of this parameter provides valuable information to physicians in many cases. However, this parameter has limitations and is not suitable for certain clinical applications, such as assessing treatment response and differentiating between benign and malignant tumors. In contrast, utilizing dynamic imaging systems can yield significant information through the extraction of kinetic features and quantitative analysis based on temporal data. However, the use of dynamic PET imaging in a clinical setting can be challenging due to factors such as prolonged scan times (> 60 minutes),... 

Breast cancer is the second leading cause of cancer death among women. Mammography is considered the “gold standard” in the evaluation of the breast lesions from an imaging perspective. But this modality has limitations. Completed studies are used to overcome these limitations. The Positron Emission Mammography (PEM) is the one of these complementary methods. PEM imaging is a molecular imaging modality for the diagnosis of breast cancer. In this thesis, a commercial PEM system as Naviscan PEM has been simulated using the GATE program. This system consists of two parallel planes of detectors, each detector consists of 12 blocks with 6 × 2 array and each block consists of 169 crystals with 13... 

The purpose of designing the foundation is to transfer the load of the structure to the subsoil without creating shear failure and additional settlement in the soil. Therefore, choosing the appropriate bearing capacity is an important point that should be considered in any project. Determining the bearing capacity of foundations is one of the topics that has long been considered by researchers and geotechnical engineering designers. For this reason, its design is not considered a new issue, but the application of new methods and the development of computers, raises new perspectives on this issue that justifies new studies.Most of the recent study, which have done so far on bearing capacity,... 

Density Functional Theory is one of the most robust Ab-intio methods for describing the structural and electronic properties of a wide range of materials. The ability to predict the material properties changes due to targeted material manipulation at the atomic scale has reduced the cost of many empirical experiments. It has improved the knowledge and understanding of the investigation and producing new materials and devices. Tow dimensional heterostructures are highly regarded due to their unique optoelectronic properties, potential application in nanoelectronic devices, energy storage devices, solid-state devices, and photovoltaic devices. In this study, the two-dimensional materials...