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Synthesis of a novel magnetic starch-alginic acid-based biomaterial for drug delivery
, Article Carbohydrate Research ; Volume 487 , 2020 ; Forouzandehdel, S ; Rezghi Rami, M ; Sharif University of Technology
Elsevier Ltd
2020
Abstract
The magnetic composite hydrogel was fabricated by the graft copolymerization of itaconic acid (IA) onto starch and Alginic acid in the presence graphene sheets (Gr) and Fe3O4 nanoparticles (Fe3O4@Gr-IA/St-Alg) for Guaifenesin (GFN) delivery and wound healing. The Fe3O4@Gr-IA/St-Alg biomaterial is a hydrogel network endowed the material with magnetic property. In addition, GFN not only achieved effectively bound to the magnetic hydrogel, but also released in a controlled manner. The using external magnetic field has significantly positive influence on the drug release rate. To close, these hydrogel drug carriers offer a favorable platform for magnetically targeted drug delivery as well as a...
Measuring of the Barrier around of the C-N Band in the Molecule of 2-Cyano Ethyl Morpholine-4-Carbo Dithioate by DNMR
, M.Sc. Thesis Sharif University of Technology ; Tafazzoli, Mohsen (Supervisor)
Abstract
In this research, the barrier around C-N bond in the molecule of 2-cyano ethyl morpholine-4-carbo dithioate was calculated by dynamic NMR. The 1H-NMR spectra of sample were recorded between temperatures of 240-332 K and 240-328 K in chloroform and acetone solvents, respectively. By analyzing the spectra by SpinWorks software, thermodynamic parameters (ΔG# , ΔH# , ΔS# ) extracded and compared with the data of quantum calculations . In quantum calculations, we compared data in two level (HF and B3LYP ).Consequently, the data of B3LYP method was better .Experimental ΔG# for internal rotation around C-N bond in 2-cyano ethyl morpholine-4-carbo dithioate was 14.04 kcal mol -1 and compared to...
Synthesis of magnetic bio-nanocomposites for drug release and adsorption applications
, Article South African Journal of Chemical Engineering ; Volume 42 , 2022 , Pages 115-126 ; 10269185 (ISSN) ; Meskini, M ; Qarebaghi, L. M ; Salami, M ; Forouzandehdel, S ; Cheraghali, M ; Sharif University of Technology
Elsevier B.V
2022
Abstract
Aims: Synthesis of nanocarrier Fe3O4/silica-starch/PNVCL for drug delivery and Fe3O4/GO-starch for antibiotic removal applications Background: In the first part, the new magnetic nanocomposite including Fe3O4 nanoparticles coated with silica, anchored starch nanoparticles, and poly(N-vinylcaprolactam) and then, loaded by acetazolamide. In the second part, magnetic starch nanocomposites were synthesized and modified with graphene oxide. Methods: The drug loading, release and intrinsic cytotoxicity were measured. Also, the potential of Fe3O4/GO-starch as an adsorbent to remove cephalexin antibiotics from aqueous solutions was evaluated. Result: In the first part, the maximum drug adsorption...
Therapeutic Potentials and Candidates for COVID-19
, Article Iranian Journal of Science ; Volume 47, Issue 4 , 2023 , Pages 1283-1297 ; 27318095 (ISSN) ; Meskini, M ; Rezaei Khozani, N ; Forouzandehdel, S ; Momtaz, S ; Ghosh, S ; Rezaei, N ; Abdolghaffari, A. H ; Sharif University of Technology
Springer Science and Business Media Deutschland GmbH
2023
Abstract
The current coronavirus disease 2019 (COVID-19) outbreak spread rapidly worldwide. Yet, there is no identifiable antiviral treatment, so an effective drug is urgently needed. Preventive strategies and oxygen therapy are the main practical approaches to prevent and treat COVID-19. Clinical trials are in progress for the antiviral and immunomodulation agents that eventually are being developed for COVID-19 treatment. Pharmacological, immunotherapies, natural-based supplements, biologics, and combination therapies interventions have been established. The concept of drug repurposing was re-visited, and many conventional antivirals or immunosuppresses were evaluated for Efficacy against COVID-19...
Design and application of (Fe3O4)-GOTfOH based AgNPs doped starch/PEG-poly (acrylic acid) nanocomposite as the magnetic nanocatalyst and the wound dress
, Article Journal of Molecular Structure ; Volume 1214 , 2020 ; Meskini, M ; Rami, M. R ; Sharif University of Technology
Elsevier B.V
2020
Abstract
As a novel, recyclable nanocatalyst, (Fe3O4)-GOTfOH based Ag nanoparticles doped Starch/PEG-poly (acrylic acid) nanocomposite (Fe3O4@GOTfOH/Ag/St-PEG-AcA) was applied for one-pot synthesis of 2,4,6-triarylpyridine derivatives under water solvent conditions. The prepared nanocomposite was also evaluated in terms of biocompatibility for wound healing. Fe3O4@GOTfOH/Ag/St-PEG-AcA could be easily removed from the mixture of the reaction by an external magnet and recycled without a considerable decrease of activity even after 10 runs. The new nanocatalyst offered better efficiencies than other commercially available sulfonic acid catalysts. In terms of the bioactivity of nanocatalyst, good...
Synthesis of the core/shell structure of polycaprolactone@curcumin-gluten for drug delivery applications
, Article Biointerface Research in Applied Chemistry ; Volume 13, Issue 1 , 2023 ; 20695837 (ISSN) ; Forouzandehdel, S ; Salami, M ; Hataminejad, E ; Jafar, M ; Sharif University of Technology
AMG Transcend Association
2023
Abstract
In this study, polycaprolactone (PCL) nanoparticles were effectively synthesized as novel drug delivery systems by the electrospray method. Curcumin (Cur) was selected as the model drug with further enhanced stability of its composition with gluten (GLU). The physical-chemical characterization, including FTIR, UV-vis, and thermal analysis of PCL@Cur-GLU nanocapsules, are explored. The in vitro release profiles described by Ritger–Peppas models were also investigated, showing sustained release for 15 h after a burst release within the first five hours. © 2022 by the authors
The Effect of Teaching Critico-Creative Thinking Skills on Iranian In-Service EFL Teachers’ Critical Thinking, Perception, and Attitude
, M.Sc. Thesis Sharif University of Technology ; Alemi, Minoo (Supervisor)
Abstract
In this millennium there has been a thought-provoking dispute over the inclusion of Critical Thinking (CT) programs into teaching syllabi; this inspiring challenge of change has led researcher to investigate the teachability and transferability of Critical Thinking. Thus, this study investigated whether explicit critical thinking instruction can foster critical thinking skills of in-service EFL teachers and enhance their disposition, perception and attitude. To fulfill the purposes of this study, California Critical Thinking Skill Tests (CCTST), EMI Critical Thinking Disposition Inventory, as well as perception and attitude questionnaires were utilized. The participants of this research were...
Simulation-based Service Allocation in Cloud Manufacturing Environments for a Specific Product Type Considering Focusing on Uncertainty in Services' Supply Demand
, M.Sc. Thesis Sharif University of Technology ; Fatahi Valilai, Omid (Supervisor)
Abstract
Nowadays, both academic and industrial environment have come to the conclusion that recent manufacturing paradigms are probably no longer applicable to the ever-changing today’s business environments. That is why manufacturing is moving gradually from production-oriented to service-oriented approaches. Service-oriented manufacturing results in a variety of services through a product life cycle which create an abundance of high value-added markets promoting efficient collaboration and amazing innovation. Cloud Manufacturing as an intelligent newly developed service-oriented manufacturing paradigm provides platforms of shared and interconnected distributed manufacturing resources and...
Moral Hazard in New Models of Islamic Banking
, M.Sc. Thesis Sharif University of Technology ; Nilli, Farhad (Supervisor)
Abstract
This paper by using the basic Principal-Agent model, investigate the possibility of moral hazard in relation of the bank-borrower, meaning the deviation of the granted facility - for the three proposed models in the Islamic Banking (interest free). These models include the use of only authorized exchange contracts, the use of partnership contracts and the combined use of authorized exchange contracts and partnership. This study, by accepting the Mirakhor (2011) model as the optimal case, make sure that in Islamic society, by establishing assumptions such as honesty, the probability of occurrence of moral hazard is low; Hence, moral hazard is not an inherent problem of the Islamic banking...
Probability of missed detection as a criterion for receiver placement in MIMO PCL
, Article IEEE National Radar Conference - Proceedings, 7 May 2012 through 11 May 2012, Atlanta, GA ; 2012 , Pages 0924-0927 ; 10975659 (ISSN) ; 9781467306584 (ISBN) ; Chitgarha, M. M ; Radmard, M ; Nayebi, M. M ; Sharif University of Technology
IEEE
2012
Abstract
Using multiple antennas at the transmit and receive sides of a passive radar brings both the benefits of MIMO radar and passive radar. However one of the obstacles arisen in such configuration is the receive antennas placement in proper positions so that the radar performance is improved. Here we just consider the case of positioning one receiver among multiple illuminators of opportunity. Indeed it is a start for the solution of optimizing the geometry of the multiple receivers in a passive radar
An efficient method for the ring opening of epoxides with aromatic amines by Sb(III) chloride under microwave irradiation
, Article Journal of Chemical Research ; Issue 4 , 2008 , Pages 220-221 ; 03082342 (ISSN) ; Hashemi, M. M ; Mottaghi, M. M ; Foroughi, M. M ; Sharif University of Technology
2008
Abstract
SbCl3 supported on montmorillonite K-10 is an efficient catalyst for the ring opening of epoxides with aromatic amines under solvent-free conditions and microwave irradiation to give the corresponding b-amino alcohols in high yields with high regioselectivity
Resource allocation for uav-enabled integrated sensing and communication (isac) via multi-objective optimization
, Article ICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings ; Volume 2023-June , 2023 ; 15206149 (ISSN); 978-172816327-7 (ISBN) ; Naghsh, M. M ; Karbasi, M ; Nayebi, M. M ; Sharif University of Technology
Institute of Electrical and Electronics Engineers Inc
2023
Abstract
In this paper, we consider an integrated sensing and communication (ISAC) system with wireless power transfer (WPT) where an unmanned aerial vehicle (UAV)-based radar serves a group of energy-limited communication users in addition to its sensing functionality. In this architecture, the radar senses the environment in phase 1 (namely sensing phase) and mean-while, the communications users (nodes) harvest and store the energy from the radar transmit signal. The stored energy is then used for information transmission from the nodes to UAV in phase 2, i.e., uplink phase. Performance of the radar system depends on the transmit signal as well as the receive filter; the energy of the transmit...
MIMO radar signal design to improve the MIMO ambiguity function via maximizing its peak
, Article Signal Processing ; Volume 118 , 2016 , Pages 139-152 ; 01651684 (ISSN) ; Radmard, M ; Nazari Majd, M ; Karbasi, S. M ; Nayebi, M. M ; Sharif University of Technology
Elsevier
2016
Abstract
One of the important obstacles in MIMO (Multiple Input Multiple Output) radars is the issue of designing proper transmit signals. Indeed, the capability of signal design is a significant advantage in MIMO radars, through which, the system can achieve much better performance. Many different aspects of this performance improvement have been considered yet, and the transmit signals have been designed to attain such goal, e.g., getting higher SNR or better detector's performance at the receiver. However, an important tool for evaluating the radar's performance is its ambiguity function. In this paper, we consider the problem of transmit signal design, in order to optimize the ambiguity function...
Detection-localization tradeoff in MIMO radars
, Article Radioengineering ; Volume 26, Issue 2 , 2017 , Pages 581-587 ; 12102512 (ISSN) ; Radmard, M ; Chitgarha, M. M ; Bastani, M. H ; Nayebi, M. M ; Sharif University of Technology
2017
Abstract
Two gains play key roles in recently developed MIMO wireless communication systems: "spatial diversity" gain and "spatial multiplexing" gain. The diversity gain refers to the capability to decrease the error rate of the MIMO channel, while the multiplexing gain implicitly refers to the amount of increase in the capacity of the MIMO channel. It has been shown that there is a fundamental tradeoff between these two types of gains, meaning interplay between increasing reliability (via an increase in the diversity gain) and increasing data rate (via an increase in the multiplexing gain). On the other hand, recently, MIMO radars have attracted much attention for their superior ability to enhance...
Antenna placement and power allocation optimization in MIMO detection
, Article IEEE Transactions on Aerospace and Electronic Systems ; Vol. 50, Issue 2 , April , 2014 , pp. 1468-1478 ; Chitgarha, M. M ; Majd, M. N ; Nayebi, M. M ; Sharif University of Technology
2014
Abstract
It is a well known fact that using multiple antennas at transmit and receive sides improves the detection performance. However, in such multiple-input multiple-output (MIMO) configuration, proper positioning of transmitters and receivers is a big challenge that can have significant influence on the performance of the overall system. In addition, determining the power of each transmitter under a total power constraint is a problem that should be solved in order to enhance the performance and coverage of such a system. In this paper, we design the Neyman-Pearson detector under the Rayleigh scatter model and use it to introduce a criterion for the antenna placement at both transmit and receive...
Ambiguity function of MIMO radar with widely separated antennas
, Article Proceedings International Radar Symposium ; 16 -18 June , 2014 ; ISSN: 21555753 ; Chitgarha, M. M ; Nazari Majd, M ; Nayebi, M. M ; Sharif University of Technology
2014
Abstract
There has been much interest, recently, towards exploiting the Multiple-Input Multiple-Output (MIMO) technique in radar. It is shown that using multiple antennas at transmit and receive sides can improve the performance of the system. However, in order to analyze the system's performance, its ambiguity function, i.e. the ambiguity function of a MIMO radar, is needed to be defined. In this paper, beginning from the information theoretic definitions, we derive such function, specifically for a MIMO radar with widely separated antennas
Choosing the position of the receiver in a MISO passive radar system
, Article European Microwave Week 2012: "Space for Microwaves", EuMW 2012, Conference Proceedings - 9th European Radar Conference, EuRAD 2012 ; 2012 , Pages 318-321 ; 9782874870293 (ISBN) ; Majd, M. N ; Radmard, M ; Nayebi, M. M ; Sharif University of Technology
2012
Abstract
By combining the two ideas of MIMO (Multiple Input Multiple Output) and PCL (Passive Coherent Location) in radar, one can achieve the advantages of both recently developed techniques simultaneously. While using multiple antennas at the receive side provides a spatial diversity of the object to be detected, using multiple illuminators of opportunity, most importantly, makes the radar covert to the interceptors. One obstacle in such MIMO configuration is choosing the positions of the receive antennas. In this paper, after analyzing the Neyman-Pearson detector for the DVB-T based PCL, we introduce the probability of missed detection as a criterion to place the receive antenna. Here, we only...
Adaptive filtering techniques in passive radar
, Article Proceedings International Radar Symposium, Dresden ; Volume 2 , June , 2013 , Pages 1067-1078 ; 21555753 (ISSN) ; 9783954042234 (ISBN) ; Radmard, M ; Majd, M. N ; Nayebi, M. M ; Sharif University of Technology
2013
Abstract
One of the most important obstacles in passive radar applications is removing the direct signal from the target channel. Otherwise, week echoes from the targets in the target channel would be ignored due to the limited dynamic range of the system. One of the most effective techniques in this field is using adaptive filters. In this paper various adaptive filters are introduced and their performances are shown and compared
Ambiguity function based receiver placement in multi-site radar
, Article 2016 CIE International Conference on Radar, RADAR 2016, 10 October 2016 through 13 October 2016 ; 2017 ; 9781509048281 (ISBN) ; Chitgarha, M. M ; Nazari Majd, M ; Nayebi, M. M ; Sharif University of Technology
2017
Abstract
It has been shown that using multiple antennas in a radar system improves the performance considerably, since multiple target echoes are received from different aspect angles of the target. In this way, the target detection is improved. However, when using multiple antennas, some problems, such as designing the transmit signals, synchronization, etc. emerge that should be solved. One of such problems is the receiver placement. Receiver placement deals with choosing a proper position for the receive antenna in order to optimize the whole system's performance. In this paper, a receiver placement procedure based on improving the radar ambiguity function is proposed for the case of a multisite...
Improving MIMO radar's performance through receivers' positioning
, Article IET Signal Processing ; Volume 11, Issue 5 , 2017 , Pages 622-630 ; 17519675 (ISSN) ; Radmard, M ; Nazari Majd, M ; Nayebi, M. M ; Sharif University of Technology
Institution of Engineering and Technology
2017
Abstract
By employing the MIMO (multiple-input-multiple-output) technology in radar, some new problems emerged, that, in order to benefit the MIMO gains in radar, it was necessary to solve them suitably. One of such obstacles is determining the positions of receive antennas in a MIMO radar system with widely separated antennas (WS MIMO radar), since it is shown that the antennas' positions affect the whole system's performance considerably. In this study, a proper receivers' positioning procedure is proposed. To do this end, four criteria are developed based on the proposed MIMO detector and the MIMO ambiguity function. The simulations verify that the proposed positioning procedure improves the...